REACTOME_INTERLEUKIN_23_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 P4HB Protein disulfide-isomerase [1] -0.05[2] 0.01[3] -0.10[4] -0.27[5] -0.20[6] -0.24[7]
2 STAT3 Signal transducer and activator of transcription 3 [8] 0.47[9] -0.80[10] 0.50[11] 1.53[12] 0.76[13] 1.62[14]
3 TYK2 Non-receptor tyrosine-protein kinase TYK2 [15] 1.06[16] 1.65[17] 2.34[18] 2.03[19] 2.92[20] 1.20[21]
4 IL23A Interleukin-23 subunit alpha [22] -2.23[23] -1.88[24] -3.07[25] -3.65[26] -2.62[27] -4.57[28]
5 STAT4 Signal transducer and activator of transcription 4 [29] -4.92[30] -3.62[31] -2.53[32] 2.92[33] 1.69[34] 0.24[35]
6 JAK2 Tyrosine-protein kinase JAK2 [36] 0.15[37] 0.37[38] 0.49[39] 2.05[40] 2.61[41] 1.92[42]
7 IL12RB1 Interleukin-12 receptor subunit beta-1 [43] -2.21[44] -1.79[45] -1.76[46] -1.31[47] -2.24[48] -1.62[49]
8 IL23R Interleukin-23 receptor [50] -2.14[51] -0.73[52] 1.72[53] -1.64[54] -1.93[55] -2.30[56]
9 IL12B Interleukin-12 subunit beta [57] [58] [59] [60] [61] [62] [63]
[1]
ref_hepatocyte P4HB
Mean 450
Standard deviation 2.3e+02
Values 4e+02 2.9e+02 2.9e+02 8.4e+02 4.3e+02
[2]
HepG2 P4HB
Mean 1.02e+03
Standard deviation 1.8e+02
Values 1.1e+03 8.9e+02
[3]
HepG2.C3A P4HB
Mean 803
Standard deviation 1.4e+02
Values 9e+02 7e+02
[4]
HuH.7 P4HB
Mean 483
Standard deviation 9.6
Values 4.7e+02 4.9e+02 4.8e+02
[5]
SNU475 P4HB
Mean 280
Standard deviation 57
Values 3.2e+02 2.4e+02
[6]
THLE P4HB
Mean 340
Standard deviation 46
Values 3.1e+02 3.7e+02
[7]
liver P4HB
Mean 931
Standard deviation 3.2e+02
Values 9.5e+02 6.2e+02 1.4e+03 7.8e+02
[8]
ref_hepatocyte STAT3
Mean 30.1
Standard deviation 11
Values 26 25 18 46 36
[9]
HepG2 STAT3
Mean 97.5
Standard deviation 10
Values 90 1e+02
[10]
HepG2.C3A STAT3
Mean 30.7
Standard deviation 5.2
Values 34 27
[11]
HuH.7 STAT3
Mean 49.1
Standard deviation 15
Values 47 65 35
[12]
SNU475 STAT3
Mean 65.4
Standard deviation 12
Values 74 57
[13]
THLE STAT3
Mean 44.3
Standard deviation 6
Values 40 49
[14]
liver STAT3
Mean 227
Standard deviation 42
Values 1.9e+02 2.3e+02 2.8e+02 2e+02
[15]
ref_hepatocyte TYK2
Mean 4.82
Standard deviation 1.6
Values 2.6 4 5.2 6.8 5.6
[16]
HepG2 TYK2
Mean 23.5
Standard deviation 0.9
Values 23 24
[17]
HepG2.C3A TYK2
Mean 26.8
Standard deviation 2.6
Values 29 25
[18]
HuH.7 TYK2
Mean 28.1
Standard deviation 8.5
Values 35 19 31
[19]
SNU475 TYK2
Mean 14.9
Standard deviation 0.21
Values 15 15
[20]
THLE TYK2
Mean 31.6
Standard deviation 1.6
Values 33 31
[21]
liver TYK2
Mean 27.2
Standard deviation 3.5
Values 31 24 24 30
[22]
ref_hepatocyte IL23A
Mean 1.11
Standard deviation 1.6
Values 0 1 3.9 0.55 0.081
[23]
HepG2 IL23A
Mean 0.557
Standard deviation 0.48
Values 0.9 0.21
[24]
HepG2.C3A IL23A
Mean 0.535
Standard deviation 0.15
Values 0.64 0.43
[25]
HuH.7 IL23A
Mean 0.153
Standard deviation 0.09
Values 0.098 0.26 0.1
[26]
SNU475 IL23A
Mean 0.0669
Standard deviation 0.03
Values 0.088 0.046
[27]
THLE IL23A
Mean 0.158
Standard deviation 0.02
Values 0.17 0.14
[28]
liver IL23A
Mean 0.115
Standard deviation 0.089
Values 0.094 0 0.21 0.16
[29]
ref_hepatocyte STAT4
Mean 0.825
Standard deviation 0.62
Values 0 1.4 0.35 1 1.3
[30]
HepG2 STAT4
Mean 0.0637
Standard deviation 0.025
Values 0.046 0.082
[31]
HepG2.C3A STAT4
Mean 0.119
Standard deviation 0.044
Values 0.087 0.15
[32]
HuH.7 STAT4
Mean 0.164
Standard deviation 0.023
Values 0.16 0.14 0.19
[33]
SNU475 STAT4
Mean 4.7
Standard deviation 1.3
Values 5.6 3.8
[34]
THLE STAT4
Mean 2.3
Standard deviation 1.2
Values 3.1 1.5
[35]
liver STAT4
Mean 2.39
Standard deviation 1.1
Values 3 1.5 1.4 3.7
[36]
ref_hepatocyte JAK2
Mean 0.762
Standard deviation 0.48
Values 1.3 1.3 0.62 0.18 0.5
[37]
HepG2 JAK2
Mean 1.97
Standard deviation 1.3
Values 1 2.9
[38]
HepG2.C3A JAK2
Mean 1.75
Standard deviation 0.67
Values 1.3 2.2
[39]
HuH.7 JAK2
Mean 1.23
Standard deviation 0.34
Values 1.2 1.6 0.9
[40]
SNU475 JAK2
Mean 2.37
Standard deviation 0.1
Values 2.3 2.4
[41]
THLE JAK2
Mean 4.02
Standard deviation 0.77
Values 4.6 3.5
[42]
liver JAK2
Mean 7.06
Standard deviation 3.8
Values 4.7 11 2.9 9.8
[43]
ref_hepatocyte IL12RB1
Mean 0.675
Standard deviation 0.22
Values 0.83 0.53 0.99 0.52 0.51
[44]
HepG2 IL12RB1
Mean 0.342
Standard deviation 0.035
Values 0.37 0.32
[45]
HepG2.C3A IL12RB1
Mean 0.347
Standard deviation 0.0048
Values 0.35 0.34
[46]
HuH.7 IL12RB1
Mean 0.23
Standard deviation 0.036
Values 0.21 0.21 0.27
[47]
SNU475 IL12RB1
Mean 0.205
Standard deviation 0.04
Values 0.18 0.23
[48]
THLE IL12RB1
Mean 0.124
Standard deviation 0.1
Values 0.2 0.053
[49]
liver IL12RB1
Mean 0.536
Standard deviation 0.24
Values 0.35 0.87 0.57 0.36
[50]
ref_hepatocyte IL23R
Mean 0.112
Standard deviation 0.14
Values 0 0.083 0.33 0 0.15
[51]
HepG2 IL23R
Mean 0.0594
Standard deviation 0.019
Values 0.046 0.073
[52]
HepG2.C3A IL23R
Mean 0.12
Standard deviation 0.073
Values 0.068 0.17
[53]
HuH.7 IL23R
Mean 0.426
Standard deviation 0.027
Values 0.4 0.46 0.42
[54]
SNU475 IL23R
Mean 0.027
Standard deviation 0.012
Values 0.019 0.035
[55]
THLE IL23R
Mean 0.0254
Standard deviation 0.0059
Values 0.03 0.021
[56]
liver IL23R
Mean 0.0557
Standard deviation 0.027
Values 0.024 0.043 0.077 0.079
[57]
ref_hepatocyte IL12B
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[58]
HepG2 IL12B
Mean 0
Standard deviation 0
Values 0 0
[59]
HepG2.C3A IL12B
Mean 0
Standard deviation 0
Values 0 0
[60]
HuH.7 IL12B
Mean 0
Standard deviation 0
Values 0 0 0
[61]
SNU475 IL12B
Mean 0
Standard deviation 0
Values 0 0
[62]
THLE IL12B
Mean 0.0139
Standard deviation 0.0029
Values 0.012 0.016
[63]
liver IL12B
Mean 0.0125
Standard deviation 0.014
Values 0.024 0 0 0.026