REACTOME_INTERLEUKIN_15_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 STAT3 Signal transducer and activator of transcription 3 [1] -0.12[2] -1.47[3] -0.84[4] -0.83[5] -1.26[6] 0.96[7]
2 GRB2 Growth factor receptor-bound protein 2 [8] 0.53[9] 0.51[10] 0.53[11] -0.52[12] -0.31[13] -1.15[14]
3 SHC1 SHC-transforming protein 1 [15] 0.49[16] 0.86[17] 0.83[18] 1.58[19] 1.36[20] -0.66[21]
4 JAK1 Tyrosine-protein kinase JAK1 [22] -0.16[23] -0.52[24] -0.45[25] -0.44[26] 0.49[27] 0.09[28]
5 IL15RA Interleukin-15 receptor subunit alpha [29] -6.56[30] -9.11[31] -9.17[32] -2.54[33] -2.29[34] -2.81[35]
6 SOS1 Son of sevenless homolog 1 [36] -0.77[37] 0.91[38] 0.31[39] -0.23[40] -0.70[41] -0.90[42]
7 STAT5B Signal transducer and activator of transcription 5B [43] 0.69[44] 0.46[45] 1.06[46] 0.48[47] -0.09[48] 0.18[49]
8 SOS2 Son of sevenless homolog 2 [50] -0.70[51] 0.58[52] -0.30[53] 0.62[54] 0.77[55] 0.40[56]
9 STAT5A Signal transducer and activator of transcription 5A [57] -2.62[58] -1.30[59] -2.33[60] -1.92[61] -0.87[62] -1.21[63]
10 GAB2 GRB2-associated-binding protein 2 [64] 0.89[65] 0.83[66] 0.97[67] -0.15[68] 0.23[69] -0.90[70]
11 IL15 Interleukin-15 [71] -2.67[72] -2.39[73] -0.43[74] -3.23[75] -1.28[76] -2.33[77]
12 IL2RG Cytokine receptor common subunit gamma [78] -2.32[79] -4.06[80] -3.52[81] -4.67[82] [83] -1.55[84]
13 IL2RB Interleukin-2 receptor subunit beta [85] -5.44[86] -5.85[87] -6.93[88] -3.89[89] -6.02[90] 0.10[91]
14 JAK3 Tyrosine-protein kinase JAK3 [92] 1.57[93] 4.00[94] -2.12[95] -1.71[96] -0.68[97] 1.65[98]
[1]
ref_hepatocyte STAT3
Mean 30.1
Standard deviation 11
Values 26 25 18 46 36
[2]
HepG2 STAT3
Mean 97.5
Standard deviation 10
Values 90 1e+02
[3]
HepG2.C3A STAT3
Mean 30.7
Standard deviation 5.2
Values 34 27
[4]
HuH.7 STAT3
Mean 49.1
Standard deviation 15
Values 47 65 35
[5]
SNU475 STAT3
Mean 65.4
Standard deviation 12
Values 74 57
[6]
THLE STAT3
Mean 44.3
Standard deviation 6
Values 40 49
[7]
liver STAT3
Mean 227
Standard deviation 42
Values 1.9e+02 2.3e+02 2.8e+02 2e+02
[8]
ref_hepatocyte GRB2
Mean 20.7
Standard deviation 5.5
Values 27 26 20 14 17
[9]
HepG2 GRB2
Mean 104
Standard deviation 4.7
Values 1e+02 1.1e+02
[10]
HepG2.C3A GRB2
Mean 83.1
Standard deviation 0.44
Values 83 83
[11]
HuH.7 GRB2
Mean 86.7
Standard deviation 7.6
Values 89 78 93
[12]
SNU475 GRB2
Mean 55.7
Standard deviation 1.4
Values 55 57
[13]
THLE GRB2
Mean 58.8
Standard deviation 3.7
Values 56 61
[14]
liver GRB2
Mean 36.1
Standard deviation 16
Values 50 22 50 22
[15]
ref_hepatocyte SHC1
Mean 16.6
Standard deviation 7.2
Values 5.8 17 19 26 16
[16]
HepG2 SHC1
Mean 82
Standard deviation 0.099
Values 82 82
[17]
HepG2.C3A SHC1
Mean 84.9
Standard deviation 11
Values 77 93
[18]
HuH.7 SHC1
Mean 85.9
Standard deviation 2.4
Values 89 84 85
[19]
SNU475 SHC1
Mean 191
Standard deviation 36
Values 2.2e+02 1.7e+02
[20]
THLE SHC1
Mean 150
Standard deviation 11
Values 1.4e+02 1.6e+02
[21]
liver SHC1
Mean 40.4
Standard deviation 11
Values 37 32 56 37
[22]
ref_hepatocyte JAK1
Mean 15.2
Standard deviation 7.8
Values 6.8 27 18 14 10
[23]
HepG2 JAK1
Mean 47.8
Standard deviation 11
Values 40 56
[24]
HepG2.C3A JAK1
Mean 29.8
Standard deviation 1.3
Values 31 29
[25]
HuH.7 JAK1
Mean 32.5
Standard deviation 3.3
Values 36 32 29
[26]
SNU475 JAK1
Mean 43.1
Standard deviation 5.5
Values 47 39
[27]
THLE JAK1
Mean 75.4
Standard deviation 6.9
Values 70 80
[28]
liver JAK1
Mean 62.3
Standard deviation 9.1
Values 54 75 58 62
[29]
ref_hepatocyte IL15RA
Mean 7.99
Standard deviation 7
Values 0.38 6.6 18 12 3.1
[30]
HepG2 IL15RA
Mean 0.297
Standard deviation 0.17
Values 0.42 0.18
[31]
HepG2.C3A IL15RA
Mean 0.0409
Standard deviation 0.0028
Values 0.039 0.043
[32]
HuH.7 IL15RA
Mean 0.0405
Standard deviation 0.032
Values 0.016 0.077 0.028
[33]
SNU475 IL15RA
Mean 5.31
Standard deviation 0.015
Values 5.3 5.3
[34]
THLE IL15RA
Mean 5.78
Standard deviation 0.89
Values 5.2 6.4
[35]
liver IL15RA
Mean 4.4
Standard deviation 1.8
Values 5.8 2.5 6.1 3.2
[36]
ref_hepatocyte SOS1
Mean 6.81
Standard deviation 11
Values 27 1.9 2.2 1.3 1.5
[37]
HepG2 SOS1
Mean 14
Standard deviation 6.5
Values 9.4 19
[38]
HepG2.C3A SOS1
Mean 36.1
Standard deviation 3.7
Values 39 33
[39]
HuH.7 SOS1
Mean 24.6
Standard deviation 11
Values 22 37 15
[40]
SNU475 SOS1
Mean 22.5
Standard deviation 3.3
Values 25 20
[41]
THLE SOS1
Mean 14.8
Standard deviation 1.4
Values 16 14
[42]
liver SOS1
Mean 14.1
Standard deviation 3.8
Values 13 18 9.3 16
[43]
ref_hepatocyte STAT5B
Mean 3.99
Standard deviation 1.3
Values 4.1 3.3 2.3 4.6 5.6
[44]
HepG2 STAT5B
Mean 22.6
Standard deviation 6.3
Values 27 18
[45]
HepG2.C3A STAT5B
Mean 15.5
Standard deviation 4
Values 18 13
[46]
HuH.7 STAT5B
Mean 24.2
Standard deviation 2.2
Values 25 22 26
[47]
SNU475 STAT5B
Mean 21.5
Standard deviation 4
Values 24 19
[48]
THLE STAT5B
Mean 13.3
Standard deviation 0.2
Values 13 13
[49]
liver STAT5B
Mean 17.5
Standard deviation 4.7
Values 13 21 14 22
[50]
ref_hepatocyte SOS2
Mean 2.58
Standard deviation 0.97
Values 4 2.6 2.8 1.5 1.9
[51]
HepG2 SOS2
Mean 5.6
Standard deviation 3
Values 3.5 7.7
[52]
HepG2.C3A SOS2
Mean 10.9
Standard deviation 0.059
Values 11 11
[53]
HuH.7 SOS2
Mean 6.11
Standard deviation 1.7
Values 6.5 7.5 4.3
[54]
SNU475 SOS2
Mean 15.3
Standard deviation 6
Values 19 11
[55]
THLE SOS2
Mean 15.6
Standard deviation 2.6
Values 17 14
[56]
liver SOS2
Mean 13.1
Standard deviation 7.3
Values 7.4 19 6.2 20
[57]
ref_hepatocyte STAT5A
Mean 2.36
Standard deviation 1.6
Values 1.8 2.7 5 1.5 0.95
[58]
HepG2 STAT5A
Mean 1.35
Standard deviation 0.098
Values 1.4 1.3
[59]
HepG2.C3A STAT5A
Mean 2.72
Standard deviation 0.23
Values 2.6 2.9
[60]
HuH.7 STAT5A
Mean 1.37
Standard deviation 0.38
Values 1.1 1.8 1.2
[61]
SNU475 STAT5A
Mean 2.42
Standard deviation 0.13
Values 2.5 2.3
[62]
THLE STAT5A
Mean 4.58
Standard deviation 0.3
Values 4.8 4.4
[63]
liver STAT5A
Mean 3.96
Standard deviation 1.5
Values 3 3.5 3.3 6.2
[64]
ref_hepatocyte GAB2
Mean 1.62
Standard deviation 1.7
Values 1.2 1.9 4.5 0.25 0.31
[65]
HepG2 GAB2
Mean 10.6
Standard deviation 4.9
Values 14 7.1
[66]
HepG2.C3A GAB2
Mean 8.12
Standard deviation 3.2
Values 10 5.9
[67]
HuH.7 GAB2
Mean 9.24
Standard deviation 2.5
Values 9.6 12 6.6
[68]
SNU475 GAB2
Mean 5.63
Standard deviation 0.73
Values 6.1 5.1
[69]
THLE GAB2
Mean 6.7
Standard deviation 0.57
Values 7.1 6.3
[70]
liver GAB2
Mean 3.35
Standard deviation 1.3
Values 2.8 4.2 1.8 4.6
[71]
ref_hepatocyte IL15
Mean 1.48
Standard deviation 0.63
Values 1.3 2.4 1.7 1.2 0.69
[72]
HepG2 IL15
Mean 0.817
Standard deviation 0.14
Values 0.92 0.72
[73]
HepG2.C3A IL15
Mean 0.799
Standard deviation 0.19
Values 0.93 0.66
[74]
HuH.7 IL15
Mean 3.19
Standard deviation 0.27
Values 2.9 3.4 3.2
[75]
SNU475 IL15
Mean 0.608
Standard deviation 0.25
Values 0.43 0.79
[76]
THLE IL15
Mean 2.15
Standard deviation 0.51
Values 2.5 1.8
[77]
liver IL15
Mean 1.14
Standard deviation 0.27
Values 1.5 1.2 0.8 1.1
[78]
ref_hepatocyte IL2RG
Mean 1.04
Standard deviation 1.2
Values 0 0 0.89 1.3 3
[79]
HepG2 IL2RG
Mean 0.733
Standard deviation 0.88
Values 1.4 0.11
[80]
HepG2.C3A IL2RG
Mean 0.176
Standard deviation 0.067
Values 0.22 0.13
[81]
HuH.7 IL2RG
Mean 0.264
Standard deviation 0.039
Values 0.25 0.24 0.31
[82]
SNU475 IL2RG
Mean 0.158
Standard deviation 0.092
Values 0.093 0.22
[83]
THLE IL2RG
Mean 0
Standard deviation 0
Values 0 0
[84]
liver IL2RG
Mean 1.37
Standard deviation 1.1
Values 2.4 0.51 2.2 0.41
[85]
ref_hepatocyte IL2RB
Mean 0.407
Standard deviation 0.62
Values 0 0 0.23 0.31 1.5
[86]
HepG2 IL2RB
Mean 0.0329
Standard deviation 0.034
Values 0.057 0.0086
[87]
HepG2.C3A IL2RB
Mean 0.0199
Standard deviation 0.013
Values 0.029 0.011
[88]
HuH.7 IL2RB
Mean 0.00975
Standard deviation 0.0086
Values 0.016 0.013 0
[89]
SNU475 IL2RB
Mean 0.106
Standard deviation 0.065
Values 0.06 0.15
[90]
THLE IL2RB
Mean 0.0222
Standard deviation 0.0063
Values 0.018 0.027
[91]
liver IL2RB
Mean 1.68
Standard deviation 1.1
Values 1.7 0.61 3.3 1.1
[92]
ref_hepatocyte JAK3
Mean 0.235
Standard deviation 0.23
Values 0.61 0.026 0.15 0.078 0.31
[93]
HepG2 JAK3
Mean 2.46
Standard deviation 0.35
Values 2.7 2.2
[94]
HepG2.C3A JAK3
Mean 10.6
Standard deviation 4.3
Values 14 7.6
[95]
HuH.7 JAK3
Mean 0.158
Standard deviation 0.069
Values 0.11 0.24 0.12
[96]
SNU475 JAK3
Mean 0.279
Standard deviation 0.0072
Values 0.27 0.28
[97]
THLE JAK3
Mean 0.519
Standard deviation 0.094
Values 0.59 0.45
[98]
liver JAK3
Mean 2.86
Standard deviation 0.73
Values 2.8 2.2 2.5 3.9