REACTOME_INTERLEUKIN_10_SIGNALING | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | CCL20 | C-C motif chemokine 20 | [1] | -1.57[2] | 0.96[3] | -0.23[4] | -7.82[5] | -4.71[6] | -9.96[7] |
2 | TIMP1 | Metalloproteinase inhibitor 1 | [8] | -1.01[9] | -2.91[10] | -9.57[11] | -0.62[12] | -0.25[13] | 0.02[14] |
3 | CXCL2 | C-X-C motif chemokine 2 | [15] | -6.27[16] | -7.08[17] | -5.23[18] | -5.99[19] | -3.00[20] | 0.48[21] |
4 | TNFRSF1A | Tumor necrosis factor receptor superfamily member 1A | [22] | 0.75[23] | 0.01[24] | 0.82[25] | 1.71[26] | 0.68[27] | 0.15[28] |
5 | STAT3 | Signal transducer and activator of transcription 3 | [29] | 1.77[30] | 0.00[31] | 1.25[32] | 1.58[33] | -0.35[34] | 2.48[35] |
6 | IL1RN | Interleukin-1 receptor antagonist protein | [36] | -2.43[37] | 0.04[38] | -7.63[39] | [40] | -8.59[41] | -0.52[42] |
7 | CXCL1 | Growth-regulated alpha protein | [43] | -5.23[44] | -9.31[45] | -3.88[46] | -4.56[47] | 1.00[48] | -5.43[49] |
8 | IL1R1 | Interleukin-1 receptor type 1 | [50] | 0.65[51] | 0.01[52] | -0.12[53] | 0.52[54] | 1.98[55] | 0.85[56] |
9 | JAK1 | Tyrosine-protein kinase JAK1 | [57] | 1.73[58] | 0.94[59] | 1.64[60] | 1.97[61] | 1.41[62] | 1.60[63] |
10 | CCL3L1 | C-C motif chemokine 3-like 1 | [64] | [65] | [66] | [67] | [68] | [69] | [70] |
11 | IL18 | Interleukin-18 | [71] | 0.35[72] | -3.75[73] | 0.89[74] | 0.17[75] | -1.70[76] | -4.09[77] |
12 | ICAM1 | Intercellular adhesion molecule 1 | [78] | 3.12[79] | 2.22[80] | 3.15[81] | 1.53[82] | 2.50[83] | -0.34[84] |
13 | CCL2 | C-C motif chemokine 2 | [85] | -12.18[86] | [87] | -11.36[88] | -2.77[89] | -1.82[90] | -3.62[91] |
14 | IL10RB | Interleukin-10 receptor subunit beta | [92] | 0.68[93] | 0.22[94] | -0.28[95] | 1.13[96] | 0.05[97] | 0.10[98] |
15 | CCL3 | C-C motif chemokine 3 | [99] | [100] | [101] | [102] | -6.85[103] | [104] | -4.35[105] |
16 | CCL4 | C-C motif chemokine 4 | [106] | [107] | [108] | [109] | [110] | [111] | -3.34[112] |
17 | IL1R2 | Interleukin-1 receptor type 2 | [113] | -1.21[114] | -1.53[115] | -4.99[116] | -4.25[117] | -3.35[118] | -0.77[119] |
18 | CSF1 | Macrophage colony-stimulating factor 1 | [120] | 2.26[121] | -2.72[122] | 1.97[123] | 4.34[124] | 2.60[125] | 0.48[126] |
19 | TYK2 | Non-receptor tyrosine-protein kinase TYK2 | [127] | 2.36[128] | 2.44[129] | 3.09[130] | 2.09[131] | 1.81[132] | 2.06[133] |
20 | CCL5 | C-C motif chemokine 5 | [134] | -3.54[135] | -3.27[136] | -2.60[137] | -2.36[138] | -4.76[139] | 0.80[140] |
21 | TNFRSF1B | Tumor necrosis factor receptor superfamily member 1B | [141] | -0.91[142] | -5.29[143] | -5.44[144] | -2.03[145] | -1.59[146] | 1.53[147] |
22 | IL1B | Interleukin-1 beta | [148] | -7.48[149] | -7.62[150] | -2.78[151] | -2.25[152] | 2.13[153] | -5.13[154] |
23 | CSF3 | Granulocyte colony-stimulating factor | [155] | -0.95[156] | -4.84[157] | -4.73[158] | -5.60[159] | 4.59[160] | -7.35[161] |
24 | LIF | Leukemia inhibitory factor | [162] | 3.50[163] | 3.06[164] | 4.41[165] | 2.96[166] | 2.77[167] | -5.11[168] |
25 | CXCL10 | C-X-C motif chemokine 10 | [169] | -7.93[170] | -5.89[171] | -0.26[172] | -0.22[173] | -9.01[174] | -2.31[175] |
26 | IL6 | Interleukin-6 | [176] | -7.22[177] | [178] | -3.38[179] | 0.49[180] | 1.80[181] | [182] |
27 | FPR1 | fMet-Leu-Phe receptor | [183] | -4.05[184] | [185] | -4.81[186] | -0.12[187] | 4.26[188] | 1.46[189] |
28 | IL10RA | Interleukin-10 receptor subunit alpha | [190] | -4.42[191] | [192] | [193] | -3.30[194] | -5.64[195] | 2.71[196] |
29 | IL10 | Interleukin-10 | [197] | -0.65[198] | -1.18[199] | -0.48[200] | -0.64[201] | -2.31[202] | -1.52[203] |
30 | CCR1 | C-C chemokine receptor type 1 | [204] | -3.80[205] | -6.39[206] | 3.48[207] | 0.74[208] | -6.13[209] | 2.03[210] |
31 | CCL3L3 | [211] | [212] | [213] | [214] | [215] | [216] | [217] | |
32 | CCR2 | C-C chemokine receptor type 2 | [218] | [219] | [220] | 1.18[221] | [222] | [223] | 0.94[224] |
33 | CD86 | T-lymphocyte activation antigen CD86 | [225] | [226] | [227] | -3.25[228] | -2.75[229] | -5.98[230] | 1.42[231] |
34 | PTAFR | Platelet-activating factor receptor | [232] | 4.59[233] | 4.54[234] | 1.31[235] | 1.03[236] | -1.21[237] | 2.18[238] |
35 | CCL22 | C-C motif chemokine 22 | [239] | -0.16[240] | -0.27[241] | -1.10[242] | -0.82[243] | -2.09[244] | -2.61[245] |
36 | IL12A | Interleukin-12 subunit alpha | [246] | -0.19[247] | [248] | 1.55[249] | -0.20[250] | 0.39[251] | -3.10[252] |
37 | TNF | Tumor necrosis factor | [253] | 2.32[254] | -0.09[255] | -4.17[256] | -0.88[257] | -5.31[258] | -1.82[259] |
38 | CCR5 | C-C chemokine receptor type 5 | [260] | -4.90[261] | [262] | 3.55[263] | -4.69[264] | [265] | 0.64[266] |
39 | FCER2 | Low affinity immunoglobulin epsilon Fc receptor | [267] | [268] | [269] | [270] | [271] | [272] | -0.36[273] |
40 | IL1A | Interleukin-1 alpha | [274] | 0.79[275] | 0.12[276] | -0.54[277] | 0.70[278] | 6.25[279] | -1.51[280] |
41 | CD80 | T-lymphocyte activation antigen CD80 | [281] | [282] | [283] | -3.80[284] | 0.19[285] | -2.08[286] | 2.70[287] |
42 | PTGS2 | Prostaglandin G/H synthase 2 | [288] | [289] | -1.68[290] | -0.91[291] | 4.21[292] | 8.82[293] | 2.91[294] |
43 | CSF2 | Granulocyte-macrophage colony-stimulating factor | [295] | 1.68[296] | -2.54[297] | -1.39[298] | -0.37[299] | 6.32[300] | -1.40[301] |
44 | CCL19 | C-C motif chemokine 19 | [302] | [303] | -0.73[304] | [305] | [306] | [307] | 2.99[308] |
45 | IL12B | Interleukin-12 subunit beta | [309] | [310] | [311] | [312] | [313] | [314] | [315] |
46 | CXCL8 | Interleukin-8 | [316] | [317] | [318] | [319] | [320] | [321] | [322] |