REACTOME_INTERFERON_GAMMA_SIGNALING |
Return to index |
|
|
|
|
|
Order |
Gene |
Description |
ref_hepatocyte |
HepG2 |
HepG2.C3A |
HuH.7 |
SNU475 |
THLE |
liver |
1 |
MT2A |
Metallothionein-2 |
[1] |
-3.68[2] |
-3.57[3] |
-7.42[4] |
-7.13[5] |
-1.35[6] |
-1.41[7] |
2 |
B2M |
Beta-2-microglobulin |
[8] |
-0.48[9] |
-0.14[10] |
-0.32[11] |
0.42[12] |
0.30[13] |
0.83[14] |
3 |
HLA-A |
HLA class I histocompatibility antigen, A-68 alpha chain |
[15] |
1.63[16] |
2.01[17] |
-3.50[18] |
1.44[19] |
0.44[20] |
-0.65[21] |
4 |
HLA-C |
HLA class I histocompatibility antigen, Cw-17 alpha chain |
[22] |
0.77[23] |
0.24[24] |
-3.14[25] |
0.66[26] |
0.73[27] |
-0.25[28] |
5 |
HLA-B |
HLA class I histocompatibility antigen, B-73 alpha chain |
[29] |
-0.20[30] |
-1.39[31] |
-5.26[32] |
2.10[33] |
1.11[34] |
0.09[35] |
6 |
HLA-E |
HLA class I histocompatibility antigen, alpha chain E |
[36] |
0.97[37] |
0.96[38] |
1.01[39] |
1.59[40] |
0.25[41] |
1.61[42] |
7 |
SUMO1 |
Small ubiquitin-related modifier 1 |
[43] |
1.20[44] |
1.49[45] |
1.61[46] |
0.23[47] |
0.19[48] |
-0.11[49] |
8 |
IFI30 |
Gamma-interferon-inducible lysosomal thiol reductase |
[50] |
1.08[51] |
0.01[52] |
1.87[53] |
-1.75[54] |
-2.23[55] |
-0.13[56] |
9 |
HLA-DRA |
HLA class II histocompatibility antigen, DR alpha chain |
[57] |
-10.47[58] |
[59] |
-10.86[60] |
-4.05[61] |
-5.96[62] |
0.86[63] |
10 |
IFNGR1 |
Interferon gamma receptor 1 |
[64] |
3.58[65] |
2.60[66] |
1.62[67] |
1.32[68] |
1.09[69] |
1.12[70] |
11 |
GBP2 |
Guanylate-binding protein 2 |
[71] |
-0.67[72] |
-2.13[73] |
-0.77[74] |
0.83[75] |
-1.56[76] |
-0.19[77] |
12 |
PTPN11 |
Tyrosine-protein phosphatase non-receptor type 11 |
[78] |
3.25[79] |
3.81[80] |
4.25[81] |
2.58[82] |
3.24[83] |
2.69[84] |
13 |
STAT1 |
Signal transducer and activator of transcription 1-alpha/beta |
[85] |
2.73[86] |
1.94[87] |
3.53[88] |
4.23[89] |
1.98[90] |
2.38[91] |
14 |
SP100 |
Nuclear autoantigen Sp-100 |
[92] |
1.04[93] |
0.05[94] |
-0.34[95] |
0.90[96] |
1.24[97] |
1.16[98] |
15 |
HLA-DRB1 |
HLA class II histocompatibility antigen, DRB1-15 beta chain |
[99] |
-5.64[100] |
[101] |
[102] |
-4.41[103] |
-9.46[104] |
-0.23[105] |
16 |
GBP1 |
Guanylate-binding protein 1 |
[106] |
-1.70[107] |
-6.59[108] |
-3.18[109] |
2.73[110] |
0.96[111] |
1.21[112] |
17 |
IFNGR2 |
Interferon gamma receptor 2 |
[113] |
2.77[114] |
3.46[115] |
1.92[116] |
0.33[117] |
1.64[118] |
0.85[119] |
18 |
JAK1 |
Tyrosine-protein kinase JAK1 |
[120] |
3.31[121] |
2.93[122] |
3.60[123] |
2.32[124] |
2.99[125] |
2.96[126] |
19 |
ICAM1 |
Intercellular adhesion molecule 1 |
[127] |
4.70[128] |
4.21[129] |
5.10[130] |
1.89[131] |
4.08[132] |
1.02[133] |
20 |
IRF9 |
Interferon regulatory factor 9 |
[134] |
1.99[135] |
0.30[136] |
1.05[137] |
1.33[138] |
0.31[139] |
1.34[140] |
21 |
CD44 |
CD44 antigen |
[141] |
-4.27[142] |
-5.63[143] |
1.28[144] |
3.45[145] |
3.93[146] |
0.15[147] |
22 |
TRIM8 |
Probable E3 ubiquitin-protein ligase TRIM8 |
[148] |
3.52[149] |
3.50[150] |
3.41[151] |
1.50[152] |
1.86[153] |
0.84[154] |
23 |
TRIM21 |
E3 ubiquitin-protein ligase TRIM21 |
[155] |
0.71[156] |
-0.99[157] |
-1.06[158] |
-0.15[159] |
-1.10[160] |
-0.02[161] |
24 |
IRF7 |
Interferon regulatory factor 7 |
[162] |
-6.43[163] |
-5.30[164] |
-3.71[165] |
-1.45[166] |
-1.69[167] |
1.36[168] |
25 |
OAS1 |
2'-5'-oligoadenylate synthase 1 |
[169] |
2.17[170] |
-0.58[171] |
-5.90[172] |
-1.06[173] |
-2.49[174] |
1.00[175] |
26 |
SOCS3 |
Suppressor of cytokine signaling 3 |
[176] |
-1.34[177] |
-1.62[178] |
0.58[179] |
0.90[180] |
-0.16[181] |
1.56[182] |
27 |
IRF3 |
Interferon regulatory factor 3 |
[183] |
3.10[184] |
3.40[185] |
4.61[186] |
2.05[187] |
1.66[188] |
0.25[189] |
28 |
IRF2 |
Interferon regulatory factor 2 |
[190] |
1.71[191] |
2.23[192] |
1.55[193] |
0.60[194] |
0.68[195] |
1.09[196] |
29 |
GBP7 |
Guanylate-binding protein 7 |
[197] |
[198] |
-8.87[199] |
-1.24[200] |
-5.27[201] |
[202] |
1.75[203] |
30 |
PTPN1 |
Tyrosine-protein phosphatase non-receptor type 1 |
[204] |
3.92[205] |
3.71[206] |
3.72[207] |
3.52[208] |
2.84[209] |
1.13[210] |
31 |
TRIM26 |
Tripartite motif-containing protein 26 |
[211] |
3.58[212] |
3.73[213] |
3.66[214] |
2.46[215] |
2.06[216] |
2.06[217] |
32 |
PTPN2 |
Tyrosine-protein phosphatase non-receptor type 2 |
[218] |
1.94[219] |
3.39[220] |
4.26[221] |
1.14[222] |
1.30[223] |
1.17[224] |
33 |
HLA-DPA1 |
HLA class II histocompatibility antigen, DP alpha 1 chain |
[225] |
-4.14[226] |
-7.51[227] |
[228] |
-3.40[229] |
-5.23[230] |
1.15[231] |
34 |
GBP3 |
Guanylate-binding protein 3 |
[232] |
-1.50[233] |
-4.75[234] |
-2.47[235] |
1.86[236] |
1.86[237] |
0.25[238] |
35 |
HLA-DRB5 |
HLA class II histocompatibility antigen, DR beta 5 chain |
[239] |
-8.29[240] |
[241] |
[242] |
-6.66[243] |
[244] |
-4.42[245] |
36 |
TRIM25 |
E3 ubiquitin/ISG15 ligase TRIM25 |
[246] |
4.94[247] |
4.71[248] |
5.02[249] |
2.58[250] |
3.25[251] |
3.25[252] |
37 |
HLA-F |
HLA class I histocompatibility antigen, alpha chain F |
[253] |
0.36[254] |
-0.97[255] |
-4.63[256] |
2.98[257] |
1.13[258] |
1.46[259] |
38 |
CAMK2D |
Calcium/calmodulin-dependent protein kinase type II subunit delta |
[260] |
2.93[261] |
3.37[262] |
5.38[263] |
2.37[264] |
1.58[265] |
2.84[266] |
39 |
IRF1 |
Interferon regulatory factor 1 |
[267] |
2.29[268] |
1.96[269] |
2.58[270] |
2.95[271] |
1.97[272] |
2.26[273] |
40 |
TRIM5 |
Tripartite motif-containing protein 5 |
[274] |
2.62[275] |
1.96[276] |
3.95[277] |
2.27[278] |
0.48[279] |
1.98[280] |
41 |
PTPN6 |
Tyrosine-protein phosphatase non-receptor type 6 |
[281] |
2.34[282] |
2.66[283] |
3.72[284] |
-5.44[285] |
-0.40[286] |
1.25[287] |
42 |
TRIM14 |
Tripartite motif-containing protein 14 |
[288] |
3.77[289] |
3.69[290] |
3.73[291] |
1.63[292] |
2.73[293] |
3.16[294] |
43 |
IRF6 |
Interferon regulatory factor 6 |
[295] |
-3.22[296] |
-3.46[297] |
-3.89[298] |
-1.75[299] |
-1.58[300] |
3.16[301] |
44 |
PML |
Protein PML |
[302] |
3.03[303] |
2.16[304] |
4.34[305] |
3.58[306] |
3.10[307] |
1.67[308] |
45 |
HLA-G |
HLA class I histocompatibility antigen, alpha chain G |
[309] |
-0.22[310] |
-1.09[311] |
-5.30[312] |
0.37[313] |
-5.73[314] |
-2.37[315] |
46 |
PRKCD |
Protein kinase C delta type |
[316] |
3.90[317] |
4.28[318] |
4.24[319] |
1.19[320] |
2.37[321] |
0.36[322] |
47 |
OASL |
2'-5'-oligoadenylate synthase-like protein |
[323] |
-1.43[324] |
-2.68[325] |
-4.04[326] |
-3.27[327] |
-0.98[328] |
0.89[329] |
48 |
TRIM35 |
Tripartite motif-containing protein 35 |
[330] |
3.95[331] |
3.66[332] |
3.43[333] |
1.23[334] |
2.15[335] |
3.43[336] |
49 |
IRF8 |
Interferon regulatory factor 8 |
[337] |
-4.03[338] |
-2.81[339] |
6.29[340] |
-2.73[341] |
0.36[342] |
2.11[343] |
50 |
PIAS1 |
E3 SUMO-protein ligase PIAS1 |
[344] |
2.85[345] |
3.24[346] |
4.62[347] |
2.57[348] |
2.32[349] |
2.61[350] |
51 |
CAMK2G |
Calcium/calmodulin-dependent protein
kinase type II subunit gamma |
3.58[351] |
4.92[352] |
5.02[353] |
3.38[354] |
2.96[355] |
2.38[356] |
52 |
OAS3 |
2'-5'-oligoadenylate synthase 3 |
[357] |
5.07[358] |
2.71[359] |
-3.08[360] |
2.82[361] |
3.60[362] |
2.75[363] |
53 |
HLA-DPB1 |
HLA class II histocompatibility antigen, DP beta 1 chain |
[364] |
-6.24[365] |
-7.17[366] |
[367] |
-2.24[368] |
-0.23[369] |
1.94[370] |
54 |
TRIM38 |
E3 ubiquitin-protein ligase TRIM38 |
[371] |
2.94[372] |
2.86[373] |
-0.19[374] |
3.94[375] |
3.60[376] |
2.79[377] |
55 |
OAS2 |
2'-5'-oligoadenylate synthase 2 |
[378] |
0.65[379] |
-3.33[380] |
-7.10[381] |
0.58[382] |
0.19[383] |
2.61[384] |
56 |
SOCS1 |
Suppressor of cytokine signaling 1 |
[385] |
1.35[386] |
2.35[387] |
3.10[388] |
-0.10[389] |
-1.46[390] |
-0.03[391] |
57 |
TRIM6 |
Tripartite motif-containing protein 6 |
[392] |
-1.27[393] |
-2.58[394] |
4.50[395] |
2.87[396] |
-0.66[397] |
-1.68[398] |
58 |
HLA-DQA1 |
HLA class II histocompatibility antigen, DQ alpha 1 chain |
[399] |
[400] |
[401] |
[402] |
-5.08[403] |
-8.70[404] |
0.56[405] |
59 |
HLA-DQB1 |
HLA class II histocompatibility antigen, DQ beta 1 chain |
[406] |
-2.15[407] |
[408] |
[409] |
-2.09[410] |
[411] |
0.47[412] |
60 |
GBP4 |
Guanylate-binding protein 4 |
[413] |
0.02[414] |
2.05[415] |
1.39[416] |
3.13[417] |
1.24[418] |
3.94[419] |
61 |
TRIM68 |
E3 ubiquitin-protein ligase TRIM68 |
[420] |
-2.93[421] |
-1.79[422] |
2.34[423] |
2.73[424] |
2.18[425] |
2.74[426] |
62 |
GBP5 |
Guanylate-binding protein 5 |
[427] |
1.35[428] |
1.83[429] |
1.75[430] |
2.76[431] |
-1.38[432] |
1.12[433] |
63 |
TRIM22 |
E3 ubiquitin-protein ligase TRIM22 |
[434] |
2.73[435] |
3.07[436] |
-1.50[437] |
3.68[438] |
2.41[439] |
3.11[440] |
64 |
HLA-DQA2 |
HLA class II histocompatibility antigen, DQ alpha 2 chain |
[441] |
[442] |
[443] |
[444] |
-7.04[445] |
[446] |
-2.04[447] |
65 |
TRIM2 |
Tripartite motif-containing protein 2 |
[448] |
2.77[449] |
5.54[450] |
6.95[451] |
4.33[452] |
3.68[453] |
4.63[454] |
66 |
VCAM1 |
Vascular cell adhesion protein 1 |
[455] |
-4.22[456] |
[457] |
-0.37[458] |
2.22[459] |
5.63[460] |
4.96[461] |
67 |
TRIM3 |
Tripartite motif-containing protein 3 |
[462] |
3.72[463] |
2.43[464] |
3.47[465] |
2.79[466] |
2.57[467] |
3.21[468] |
68 |
IRF5 |
Interferon regulatory factor 5 |
[469] |
3.10[470] |
3.02[471] |
2.33[472] |
2.05[473] |
-0.20[474] |
2.41[475] |
69 |
TRIM34 |
Tripartite motif-containing protein 34 |
[476] |
-3.10[477] |
[478] |
-2.33[479] |
-1.35[480] |
-4.09[481] |
-4.20[482] |
70 |
JAK2 |
Tyrosine-protein kinase JAK2 |
[483] |
3.03[484] |
3.16[485] |
3.19[486] |
2.46[487] |
3.07[488] |
4.14[489] |
71 |
TRIM10 |
Tripartite motif-containing protein 10 |
[490] |
3.36[491] |
5.69[492] |
4.24[493] |
1.27[494] |
-5.81[495] |
0.84[496] |
72 |
CAMK2B |
Calcium/calmodulin-dependent protein kinase type II subunit beta |
[497] |
0.26[498] |
-0.92[499] |
-3.40[500] |
-1.17[501] |
-0.51[502] |
2.58[503] |
73 |
IRF4 |
Interferon regulatory factor 4 |
[504] |
-2.03[505] |
-1.56[506] |
-1.70[507] |
-2.61[508] |
-3.70[509] |
2.05[510] |
74 |
PTAFR |
Platelet-activating factor receptor |
[511] |
6.17[512] |
6.53[513] |
3.26[514] |
1.39[515] |
0.37[516] |
3.54[517] |
75 |
TRIM31 |
E3 ubiquitin-protein ligase TRIM31 |
[518] |
2.26[519] |
2.46[520] |
8.30[521] |
0.46[522] |
-2.19[523] |
0.33[524] |
76 |
FCGR1A |
High affinity immunoglobulin gamma Fc receptor I |
[525] |
[526] |
[527] |
[528] |
-5.22[529] |
[530] |
0.91[531] |
77 |
MID1 |
E3 ubiquitin-protein ligase Midline-1 |
[532] |
3.11[533] |
5.16[534] |
5.90[535] |
7.35[536] |
4.51[537] |
5.25[538] |
78 |
TRIM45 |
Tripartite motif-containing protein 45 |
[539] |
4.19[540] |
4.25[541] |
5.33[542] |
4.75[543] |
4.04[544] |
1.95[545] |
79 |
FCGR1B |
High affinity immunoglobulin gamma Fc receptor IB |
[546] |
[547] |
[548] |
-3.74[549] |
[550] |
-2.94[551] |
0.67[552] |
80 |
TRIM62 |
E3 ubiquitin-protein ligase TRIM62 |
[553] |
5.65[554] |
4.30[555] |
3.76[556] |
5.13[557] |
4.91[558] |
3.25[559] |
81 |
IFNG |
Interferon gamma |
[560] |
[561] |
[562] |
[563] |
1.00[564] |
[565] |
-0.87[566] |
82 |
CIITA |
MHC class II transactivator |
[567] |
0.41[568] |
0.37[569] |
-1.06[570] |
1.04[571] |
2.21[572] |
4.34[573] |
83 |
HLA-DQB2 |
HLA class II histocompatibility antigen, DQ beta 2 chain |
[574] |
[575] |
[576] |
[577] |
-1.72[578] |
[579] |
-1.53[580] |
84 |
TRIM29 |
Tripartite motif-containing protein 29 |
[581] |
7.18[582] |
1.31[583] |
3.12[584] |
1.27[585] |
1.01[586] |
0.40[587] |
85 |
GBP6 |
Guanylate-binding protein 6 |
[588] |
1.31[589] |
3.10[590] |
3.59[591] |
5.57[592] |
1.47[593] |
1.46[594] |
86 |
TRIM46 |
Tripartite motif-containing protein 46 |
[595] |
3.82[596] |
6.14[597] |
3.99[598] |
4.06[599] |
6.79[600] |
1.10[601] |
87 |
NCAM1 |
Neural cell adhesion molecule 1 |
[602] |
4.37[603] |
0.38[604] |
0.29[605] |
6.73[606] |
7.78[607] |
6.04[608] |
88 |
TRIM17 |
E3 ubiquitin-protein ligase TRIM17 |
[609] |
6.51[610] |
6.40[611] |
8.80[612] |
7.20[613] |
7.58[614] |
5.60[615] |
89 |
HLA-H |
Putative HLA class I histocompatibility antigen, alpha chain H |
[616] |
[617] |
[618] |
[619] |
[620] |
[621] |
[622] |
90 |
HLA-DRB4 |
HLA class II histocompatibility antigen, DR beta 4 chain |
[623] |
[624] |
[625] |
[626] |
[627] |
[628] |
[629] |
91 |
HLA-DRB3 |
HLA class II histocompatibility antigen, DR beta 3 chain |
[630] |
[631] |
[632] |
[633] |
[634] |
[635] |
[636] |
92 |
TRIM48 |
Tripartite motif-containing protein 48 |
[637] |
[638] |
[639] |
[640] |
[641] |
[642] |
[643] |
93 |
CAMK2A |
Calcium/calmodulin-dependent protein kinase type II subunit alpha |
[644] |
[645] |
[646] |
[647] |
[648] |
[649] |
[650] |
|
|
|
|
|
|
|
|
|
|