REACTOME_INTEGRIN_SIGNALING | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | FGG | Fibrinogen gamma chain | [1] | -3.46[2] | -2.20[3] | -2.06[4] | -9.70[5] | -11.66[6] | -0.71[7] |
2 | FGA | Fibrinogen alpha chain | [8] | -3.12[9] | -2.45[10] | -1.95[11] | -8.91[12] | -11.67[13] | -0.04[14] |
3 | FGB | Fibrinogen beta chain | [15] | -4.33[16] | -3.22[17] | -0.97[18] | -7.03[19] | -10.31[20] | 0.74[21] |
4 | FN1 | Fibronectin | [22] | 6.63[23] | 6.39[24] | 6.16[25] | 6.51[26] | 6.64[27] | 2.14[28] |
5 | RAP1B | Ras-related protein Rap-1b | [29] | 0.83[30] | 1.73[31] | 1.39[32] | 3.06[33] | 2.75[34] | -2.04[35] |
6 | AKT1 | RAC-alpha serine/threonine-protein kinase | [36] | 3.21[37] | 3.27[38] | 2.07[39] | 3.54[40] | 3.49[41] | -0.40[42] |
7 | GRB2 | Growth factor receptor-bound protein 2 | [43] | 4.33[44] | 4.45[45] | 4.46[46] | 4.14[47] | 3.98[48] | 0.15[49] |
8 | CRK | Adapter molecule crk | [50] | 2.93[51] | 3.15[52] | 3.10[53] | 3.35[54] | 3.67[55] | 0.69[56] |
9 | RAP1A | Ras-related protein Rap-1A | [57] | 2.09[58] | 2.31[59] | 3.03[60] | 3.37[61] | 3.06[62] | -1.44[63] |
10 | SHC1 | SHC-transforming protein 1 | [64] | 4.30[65] | 4.80[66] | 4.76[67] | 6.24[68] | 5.65[69] | 0.63[70] |
11 | TLN1 | Talin-1 | [71] | 6.13[72] | 5.04[73] | 5.70[74] | 6.70[75] | 6.64[76] | 3.21[77] |
12 | APBB1IP | Amyloid beta A4 precursor protein-binding family B member 1-interacting protein | -5.40[78] | [79] | -3.30[80] | 0.29[81] | -2.55[82] | -0.69[83] | |
13 | BCAR1 | Breast cancer anti-estrogen resistance protein 1 | [84] | 4.26[85] | 4.43[86] | 3.18[87] | 4.96[88] | 4.61[89] | -0.09[90] |
14 | CSK | Tyrosine-protein kinase CSK | [91] | 3.51[92] | 3.29[93] | 3.55[94] | 3.57[95] | 3.10[96] | -1.02[97] |
15 | PTK2 | Focal adhesion kinase 1 | [98] | 3.87[99] | 4.64[100] | 4.90[101] | 5.53[102] | 4.66[103] | 0.61[104] |
16 | PTPN1 | Tyrosine-protein phosphatase non-receptor type 1 | [105] | 4.25[106] | 4.20[107] | 3.61[108] | 5.41[109] | 4.64[110] | -0.46[111] |
17 | SOS1 | Son of sevenless homolog 1 | [112] | 3.03[113] | 4.85[114] | 4.24[115] | 4.43[116] | 3.59[117] | 0.39[118] |
18 | SRC | Proto-oncogene tyrosine-protein kinase Src | [119] | 6.16[120] | 6.43[121] | 5.31[122] | 5.99[123] | 5.09[124] | -1.00[125] |
19 | PDPK1 | 3-phosphoinositide-dependent protein kinase 1 | [126] | 5.47[127] | 6.94[128] | 5.53[129] | 5.02[130] | 5.35[131] | 2.35[132] |
20 | ITGB3 | Integrin beta-3 | [133] | 1.50[134] | -0.92[135] | 2.48[136] | 6.44[137] | 6.04[138] | 1.18[139] |
21 | RAPGEF4 | Rap guanine nucleotide exchange factor 4 | [140] | -0.89[141] | 1.20[142] | 1.99[143] | 1.92[144] | 4.25[145] | 2.75[146] |
22 | RASGRP2 | RAS guanyl-releasing protein 2 | [147] | -0.95[148] | 1.53[149] | 4.43[150] | 1.05[151] | 1.95[152] | 1.89[153] |
23 | SYK | Tyrosine-protein kinase SYK | [154] | -5.03[155] | 1.13[156] | -2.01[157] | 3.69[158] | 0.10[159] | 3.21[160] |
24 | VWF | von Willebrand factor | [161] | 4.11[162] | 2.24[163] | -0.27[164] | 3.74[165] | 1.09[166] | 5.56[167] |
25 | RAPGEF3 | Rap guanine nucleotide exchange factor 3 | [168] | 4.96[169] | 4.92[170] | 4.24[171] | 5.47[172] | 4.05[173] | 3.66[174] |
26 | ITGA2B | Integrin alpha-IIb | [175] | 6.74[176] | 7.31[177] | 7.19[178] | 6.61[179] | 4.90[180] | 2.47[181] |
27 | RASGRP1 | RAS guanyl-releasing protein 1 | [182] | 4.37[183] | 5.35[184] | 5.87[185] | 7.73[186] | 8.75[187] | 6.65[188] |