REACTOME_INSERTION_OF_TAIL_ANCHORED_PROTEINS_INTO_THE_ENDOPLASMIC_RETICULUM_MEMBRANE Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CYB5A Cytochrome b5 [1] -3.29[2] -2.83[3] -3.75[4] -4.26[5] -4.84[6] 0.01[7]
2 SEC61G Protein transport protein Sec61 subunit gamma [8] -2.09[9] -1.71[10] -1.24[11] -1.87[12] -2.31[13] -2.61[14]
3 SEC61B Protein transport protein Sec61 subunit beta [15] -1.57[16] -0.81[17] -1.31[18] -1.97[19] -1.67[20] -1.41[21]
4 APP Amyloid-beta A4 protein [22] 1.59[23] 1.03[24] 1.95[25] 2.13[26] 2.55[27] 0.87[28]
5 SERP1 Stress-associated endoplasmic reticulum protein 1 [29] 0.52[30] 1.57[31] 1.43[32] 0.41[33] 0.54[34] 1.60[35]
6 HMOX1 Heme oxygenase 1 [36] 0.73[37] -0.21[38] -1.06[39] -0.24[40] -0.47[41] -1.35[42]
7 ALDH3A2 Fatty aldehyde dehydrogenase [43] 1.21[44] 1.10[45] 0.83[46] 0.64[47] -0.21[48] 1.15[49]
8 SGTA Small glutamine-rich tetratricopeptide repeat-containing protein alpha 1.24[50] 0.88[51] 1.53[52] 0.24[53] 1.13[54] -0.30[55]
9 BAG6 Large proline-rich protein BAG6 [56] 3.04[57] 2.83[58] 2.74[59] 2.75[60] 1.73[61] 0.88[62]
10 PRNP Major prion protein [63] 2.68[64] 2.39[65] -3.78[66] 2.75[67] 3.41[68] 0.80[69]
11 GET4 Golgi to ER traffic protein 4 homolog [70] 1.08[71] 1.22[72] 1.01[73] 0.10[74] -0.05[75] 0.16[76]
12 EMD Emerin [77] 0.12[78] 0.06[79] 0.05[80] 0.93[81] 0.93[82] -1.32[83]
13 UBL4A Ubiquitin-like protein 4A [84] 0.83[85] 0.69[86] 1.12[87] 1.43[88] 1.02[89] 0.26[90]
14 STX5 Syntaxin-5 [91] 0.64[92] 1.01[93] 1.34[94] 0.46[95] 0.79[96] 0.04[97]
15 VAPA Vesicle-associated membrane protein-associated protein A [98] 3.08[99] 3.05[100] 3.62[101] 3.80[102] 3.03[103] 2.35[104]
16 UBE2J2 Ubiquitin-conjugating enzyme E2 J2 [105] 1.25[106] 1.62[107] 1.23[108] 1.38[109] 1.53[110] 0.16[111]
17 CAMLG Calcium signal-modulating cyclophilin ligand [112] 0.56[113] 1.49[114] 1.83[115] 0.50[116] 1.23[117] -0.52[118]
18 VAMP2 Vesicle-associated membrane protein 2 [119] -0.14[120] 0.21[121] 0.83[122] 0.89[123] 0.70[124] 0.54[125]
19 STX1A Syntaxin-1A [126] 2.15[127] 2.11[128] 0.88[129] 3.95[130] 2.96[131] -0.43[132]
20 OTOF Otoferlin [133] 4.33[134] 4.25[135] -0.59[136] 4.19[137] 2.71[138] 3.43[139]
21 GET1 [140] [141] [142] [143] [144] [145] [146]
22 GET3 [147] [148] [149] [150] [151] [152] [153]

[1]
ref_hepatocyte CYB5A
Mean 485
Standard deviation 5e+02
Values 1.7e+02 1.3e+02 86 8.6e+02 1.2e+03
[2]
HepG2 CYB5A
Mean 47.2
Standard deviation 8.3
Values 41 53
[3]
HepG2.C3A CYB5A
Mean 58.3
Standard deviation 3.9
Values 55 61
[4]
HuH.7 CYB5A
Mean 24.7
Standard deviation 6.7
Values 22 20 32
[5]
SNU475 CYB5A
Mean 18.2
Standard deviation 3.3
Values 21 16
[6]
THLE CYB5A
Mean 13.5
Standard deviation 0.22
Values 14 13
[7]
liver CYB5A
Mean 416
Standard deviation 2.9e+02
Values 5.6e+02 2.7e+02 7.4e+02 92
[8]
ref_hepatocyte SEC61G
Mean 185
Standard deviation 1.4e+02
Values 2.1e+02 4.2e+02 1e+02 95 93
[9]
HepG2 SEC61G
Mean 41.3
Standard deviation 5.3
Values 37 45
[10]
HepG2.C3A SEC61G
Mean 48.2
Standard deviation 13
Values 39 58
[11]
HuH.7 SEC61G
Mean 53.4
Standard deviation 12
Values 44 49 67
[12]
SNU475 SEC61G
Mean 36.3
Standard deviation 2.6
Values 38 35
[13]
THLE SEC61G
Mean 29.9
Standard deviation 2.6
Values 28 32
[14]
liver SEC61G
Mean 25.7
Standard deviation 19
Values 32 11 49 11
[15]
ref_hepatocyte SEC61B
Mean 141
Standard deviation 1.1e+02
Values 52 47 97 3e+02 2.1e+02
[16]
HepG2 SEC61B
Mean 45.2
Standard deviation 15
Values 34 56
[17]
HepG2.C3A SEC61B
Mean 68.9
Standard deviation 14
Values 59 79
[18]
HuH.7 SEC61B
Mean 38.9
Standard deviation 6.2
Values 35 35 46
[19]
SNU475 SEC61B
Mean 25.8
Standard deviation 5.1
Values 29 22
[20]
THLE SEC61B
Mean 35.4
Standard deviation 0.023
Values 35 35
[21]
liver SEC61B
Mean 45.2
Standard deviation 44
Values 75 7.2 91 7.9
[22]
ref_hepatocyte APP
Mean 58.3
Standard deviation 28
Values 31 1e+02 46 51 59
[23]
HepG2 APP
Mean 167
Standard deviation 49
Values 2e+02 1.3e+02
[24]
HepG2.C3A APP
Mean 102
Standard deviation 27
Values 1.2e+02 83
[25]
HuH.7 APP
Mean 154
Standard deviation 13
Values 1.6e+02 1.7e+02 1.4e+02
[26]
SNU475 APP
Mean 184
Standard deviation 28
Values 2e+02 1.6e+02
[27]
THLE APP
Mean 273
Standard deviation 68
Values 2.3e+02 3.2e+02
[28]
liver APP
Mean 91
Standard deviation 73
Values 32 1.7e+02 28 1.3e+02
[29]
ref_hepatocyte SERP1
Mean 46
Standard deviation 23
Values 29 26 34 73 68
[30]
HepG2 SERP1
Mean 63
Standard deviation 9.8
Values 56 70
[31]
HepG2.C3A SERP1
Mean 117
Standard deviation 20
Values 1.3e+02 1e+02
[32]
HuH.7 SERP1
Mean 84.8
Standard deviation 4.5
Values 81 90 83
[33]
SNU475 SERP1
Mean 44
Standard deviation 10
Values 51 37
[34]
THLE SERP1
Mean 53.6
Standard deviation 6.2
Values 49 58
[35]
liver SERP1
Mean 119
Standard deviation 50
Values 94 1e+02 1.9e+02 87
[36]
ref_hepatocyte HMOX1
Mean 45.4
Standard deviation 44
Values 19 4.5 1.2e+02 47 37
[37]
HepG2 HMOX1
Mean 71.8
Standard deviation 29
Values 92 52
[38]
HepG2.C3A HMOX1
Mean 33.6
Standard deviation 4.7
Values 30 37
[39]
HuH.7 HMOX1
Mean 14.9
Standard deviation 6.3
Values 10 22 12
[40]
SNU475 HMOX1
Mean 27.6
Standard deviation 4.6
Values 24 31
[41]
THLE HMOX1
Mean 26.2
Standard deviation 9.7
Values 19 33
[42]
liver HMOX1
Mean 15.2
Standard deviation 2.1
Values 16 13 18 15
[43]
ref_hepatocyte ALDH3A2
Mean 44.1
Standard deviation 25
Values 41 52 7.1 44 76
[44]
HepG2 ALDH3A2
Mean 97
Standard deviation 12
Values 89 1.1e+02
[45]
HepG2.C3A ALDH3A2
Mean 80.8
Standard deviation 15
Values 70 91
[46]
HuH.7 ALDH3A2
Mean 53.4
Standard deviation 2.9
Values 55 55 50
[47]
SNU475 ALDH3A2
Mean 49.4
Standard deviation 7.9
Values 55 44
[48]
THLE ALDH3A2
Mean 30.6
Standard deviation 2.4
Values 29 32
[49]
liver ALDH3A2
Mean 83.6
Standard deviation 21
Values 85 88 1.1e+02 55
[50]
ref_hepatocyte SGTA
Mean 25
Standard deviation 17
Values 8.8 23 54 24 15
[51]
HepG2 SGTA
Mean 56.1
Standard deviation 10
Values 63 49
[52]
HepG2.C3A SGTA
Mean 39.2
Standard deviation 4
Values 42 36
[53]
HuH.7 SGTA
Mean 49.1
Standard deviation 7.4
Values 54 41 53
[54]
SNU475 SGTA
Mean 21.1
Standard deviation 1.8
Values 20 22
[55]
THLE SGTA
Mean 43.7
Standard deviation 6.3
Values 39 48
[56]
liver SGTA
Mean 17.3
Standard deviation 9.7
Values 20 9 30 10
[57]
ref_hepatocyte BAG6
Mean 22.8
Standard deviation 5.6
Values 23 13 28 24 26
[58]
HepG2 BAG6
Mean 179
Standard deviation 32
Values 2e+02 1.6e+02
[59]
HepG2.C3A BAG6
Mean 139
Standard deviation 36
Values 1.6e+02 1.1e+02
[60]
HuH.7 BAG6
Mean 104
Standard deviation 10
Values 1.1e+02 1e+02 94
[61]
SNU475 BAG6
Mean 110
Standard deviation 18
Values 1.2e+02 98
[62]
THLE BAG6
Mean 60.5
Standard deviation 12
Values 52 69
[63]
liver BAG6
Mean 35.8
Standard deviation 4.5
Values 34 31 41 37
[64]
ref_hepatocyte PRNP
Mean 19.1
Standard deviation 12
Values 9.9 8.6 39 18 20
[65]
HepG2 PRNP
Mean 117
Standard deviation 11
Values 1.2e+02 1.1e+02
[66]
HepG2.C3A PRNP
Mean 86
Standard deviation 14
Values 76 96
[67]
HuH.7 PRNP
Mean 0.95
Standard deviation 0.22
Values 1.2 0.85 0.81
[68]
SNU475 PRNP
Mean 92.4
Standard deviation 29
Values 72 1.1e+02
[69]
THLE PRNP
Mean 163
Standard deviation 47
Values 1.3e+02 2e+02
[70]
liver PRNP
Mean 28.5
Standard deviation 5.5
Values 31 29 34 21
[71]
ref_hepatocyte GET4
Mean 17.9
Standard deviation 7.3
Values 16 18 30 15 11
[72]
HepG2 GET4
Mean 36.1
Standard deviation 0.19
Values 36 36
[73]
HepG2.C3A GET4
Mean 35.7
Standard deviation 6.9
Values 41 31
[74]
HuH.7 GET4
Mean 24.6
Standard deviation 3.7
Values 24 21 29
[75]
SNU475 GET4
Mean 13.8
Standard deviation 1.4
Values 13 15
[76]
THLE GET4
Mean 13.8
Standard deviation 2
Values 12 15
[77]
liver GET4
Mean 17
Standard deviation 11
Values 22 9.2 30 6.6
[78]
ref_hepatocyte EMD
Mean 16.2
Standard deviation 7.9
Values 5.7 10 25 22 19
[79]
HepG2 EMD
Mean 16.8
Standard deviation 2.7
Values 19 15
[80]
HepG2.C3A EMD
Mean 14.4
Standard deviation 1.8
Values 16 13
[81]
HuH.7 EMD
Mean 11.4
Standard deviation 1.3
Values 11 10 13
[82]
SNU475 EMD
Mean 22.2
Standard deviation 4.3
Values 25 19
[83]
THLE EMD
Mean 24.7
Standard deviation 2.2
Values 23 26
[84]
liver EMD
Mean 5.54
Standard deviation 4.4
Values 7.8 1.6 11 2.1
[85]
ref_hepatocyte UBL4A
Mean 13
Standard deviation 8.8
Values 4.9 16 27 9.1 7.8
[86]
HepG2 UBL4A
Mean 22.1
Standard deviation 4.3
Values 25 19
[87]
HepG2.C3A UBL4A
Mean 18
Standard deviation 0.69
Values 18 18
[88]
HuH.7 UBL4A
Mean 19.3
Standard deviation 4.3
Values 21 14 23
[89]
SNU475 UBL4A
Mean 25.1
Standard deviation 0.09
Values 25 25
[90]
THLE UBL4A
Mean 21
Standard deviation 2.3
Values 19 23
[91]
liver UBL4A
Mean 13.2
Standard deviation 5
Values 15 9.6 20 8.8
[92]
ref_hepatocyte STX5
Mean 12.9
Standard deviation 8.7
Values 4.1 3.5 19 22 15
[93]
HepG2 STX5
Mean 19.3
Standard deviation 0.34
Values 19 20
[94]
HepG2.C3A STX5
Mean 22.3
Standard deviation 6.7
Values 27 17
[95]
HuH.7 STX5
Mean 22.3
Standard deviation 2.2
Values 20 24 23
[96]
SNU475 STX5
Mean 12.8
Standard deviation 0.61
Values 13 12
[97]
THLE STX5
Mean 17.9
Standard deviation 0.9
Values 17 19
[98]
liver STX5
Mean 11.4
Standard deviation 3.3
Values 10 8.7 16 10
[99]
ref_hepatocyte VAPA
Mean 11.3
Standard deviation 4.4
Values 18 12 6.3 9 11
[100]
HepG2 VAPA
Mean 91.1
Standard deviation 18
Values 78 1e+02
[101]
HepG2.C3A VAPA
Mean 79.8
Standard deviation 8.1
Values 74 86
[102]
HuH.7 VAPA
Mean 94.5
Standard deviation 11
Values 82 97 1e+02
[103]
SNU475 VAPA
Mean 113
Standard deviation 9.3
Values 1.2e+02 1.1e+02
[104]
THLE VAPA
Mean 73.9
Standard deviation 5.5
Values 70 78
[105]
liver VAPA
Mean 49
Standard deviation 18
Values 61 36 68 31
[106]
ref_hepatocyte UBE2J2
Mean 10
Standard deviation 5.7
Values 4.7 7.7 19 11 7.9
[107]
HepG2 UBE2J2
Mean 22.8
Standard deviation 3.1
Values 25 21
[108]
HepG2.C3A UBE2J2
Mean 26.5
Standard deviation 0.19
Values 27 26
[109]
HuH.7 UBE2J2
Mean 16.1
Standard deviation 3.1
Values 15 14 20
[110]
SNU475 UBE2J2
Mean 18.9
Standard deviation 0.37
Values 19 19
[111]
THLE UBE2J2
Mean 23.2
Standard deviation 1.8
Values 22 25
[112]
liver UBE2J2
Mean 9.57
Standard deviation 5.8
Values 16 3.7 13 5.7
[113]
ref_hepatocyte CAMLG
Mean 9.66
Standard deviation 2.3
Values 12 12 7.5 8.6 8
[114]
HepG2 CAMLG
Mean 13.6
Standard deviation 3.5
Values 16 11
[115]
HepG2.C3A CAMLG
Mean 23.2
Standard deviation 11
Values 31 16
[116]
HuH.7 CAMLG
Mean 23.4
Standard deviation 4.2
Values 19 28 23
[117]
SNU475 CAMLG
Mean 9.82
Standard deviation 0.37
Values 10 9.6
[118]
THLE CAMLG
Mean 18.2
Standard deviation 1.9
Values 17 20
[119]
liver CAMLG
Mean 5.75
Standard deviation 3.3
Values 9.2 3.7 7.8 2.4
[120]
ref_hepatocyte VAMP2
Mean 7.38
Standard deviation 2
Values 9.9 5.1 8 8.2 5.7
[121]
HepG2 VAMP2
Mean 6.41
Standard deviation 1.5
Values 7.4 5.4
[122]
HepG2.C3A VAMP2
Mean 7.34
Standard deviation 3
Values 9.5 5.2
[123]
HuH.7 VAMP2
Mean 8.97
Standard deviation 0.78
Values 8.3 8.8 9.8
[124]
SNU475 VAMP2
Mean 9.81
Standard deviation 1.6
Values 11 8.7
[125]
THLE VAMP2
Mean 9.61
Standard deviation 0.14
Values 9.5 9.7
[126]
liver VAMP2
Mean 9.18
Standard deviation 10
Values 22 1 11 1.9
[127]
ref_hepatocyte STX1A
Mean 0.672
Standard deviation 0.98
Values 0.23 0.39 2.4 0.095 0.24
[128]
HepG2 STX1A
Mean 2.85
Standard deviation 0.85
Values 3.4 2.2
[129]
HepG2.C3A STX1A
Mean 2.48
Standard deviation 0.71
Values 3 2
[130]
HuH.7 STX1A
Mean 0.845
Standard deviation 0.25
Values 0.57 0.91 1.1
[131]
SNU475 STX1A
Mean 7.45
Standard deviation 3.6
Values 4.9 10
[132]
THLE STX1A
Mean 4.19
Standard deviation 1.3
Values 5.1 3.3
[133]
liver STX1A
Mean 0.426
Standard deviation 0.18
Values 0.35 0.31 0.69 0.34
[134]
ref_hepatocyte OTOF
Mean 0.00941
Standard deviation 0.021
Values 0.047 0 0 0 0
[135]
HepG2 OTOF
Mean 0.181
Standard deviation 0.19
Values 0.32 0.047
[136]
HepG2.C3A OTOF
Mean 0.153
Standard deviation 0.0038
Values 0.16 0.15
[137]
HuH.7 OTOF
Mean 0.00428
Standard deviation 0.0074
Values 0 0.013 0
[138]
SNU475 OTOF
Mean 0.124
Standard deviation 0.0043
Values 0.12 0.13
[139]
THLE OTOF
Mean 0.0494
Standard deviation 0.047
Values 0.083 0.016
[140]
liver OTOF
Mean 0.0868
Standard deviation 0.085
Values 0.16 0.029 0.15 0
[141]
ref_hepatocyte GET1
Missing
[142]
HepG2 GET1
Missing
[143]
HepG2.C3A GET1
Missing
[144]
HuH.7 GET1
Missing
[145]
SNU475 GET1
Missing
[146]
THLE GET1
Missing
[147]
liver GET1
Missing
[148]
ref_hepatocyte GET3
Missing
[149]
HepG2 GET3
Missing
[150]
HepG2.C3A GET3
Missing
[151]
HuH.7 GET3
Missing
[152]
SNU475 GET3
Missing
[153]
THLE GET3
Missing
[154]
liver GET3
Missing