REACTOME_INOSITOL_PHOSPHATE_METABOLISM Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CALM1 Calmodulin-1 [1] -0.68[2] -0.86[3] -0.30[4] 0.68[5] 0.25[6] 0.78[7]
2 IMPA2 Inositol monophosphatase 2 [8] -2.17[9] -1.14[10] -0.21[11] -1.55[12] -3.49[13] -1.47[14]
3 NUDT3 Diphosphoinositol polyphosphate phosphohydrolase 1 [15] -1.22[16] -1.77[17] -2.38[18] -2.14[19] -2.42[20] -1.30[21]
4 NUDT4 Diphosphoinositol polyphosphate phosphohydrolase 2 [22] -4.57[23] -5.00[24] -4.60[25] -5.72[26] -5.91[27] -5.07[28]
5 IP6K2 Inositol hexakisphosphate kinase 2 [29] -0.31[30] -0.02[31] 0.55[32] -1.33[33] -0.33[34] -1.00[35]
6 ITPK1 Inositol-tetrakisphosphate 1-kinase [36] 0.52[37] -0.75[38] -2.05[39] -0.88[40] -0.52[41] -0.53[42]
7 ITPKC Inositol-trisphosphate 3-kinase C [43] -1.44[44] -1.18[45] -1.24[46] -2.33[47] -1.66[48] -1.51[49]
8 MINPP1 Multiple inositol polyphosphate phosphatase 1 [50] -0.32[51] 0.39[52] -0.16[53] -1.52[54] -0.13[55] -0.34[56]
9 INPP5A Type I inositol 1,4,5-trisphosphate 5-phosphatase [57] -0.46[58] -0.27[59] -1.22[60] -2.66[61] -1.91[62] -1.51[63]
10 PTEN Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN -1.29[64] -0.12[65] 0.18[66] -1.47[67] 0.08[68] 1.64[69]
11 INPP1 Inositol polyphosphate 1-phosphatase [70] -1.91[71] -0.44[72] -0.73[73] -2.55[74] -0.84[75] -1.51[76]
12 INPPL1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 [77] 1.38[78] 0.42[79] 1.28[80] 2.42[81] 2.00[82] 0.12[83]
13 IMPA1 Inositol monophosphatase 1 [84] -0.67[85] 0.18[86] 0.11[87] 0.41[88] 0.36[89] 0.71[90]
14 PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 2.74[91] 2.13[92] 1.57[93] 1.91[94] 1.70[95] -0.50[96]
15 IPMK Inositol polyphosphate multikinase [97] -1.48[98] -0.10[99] 0.52[100] -0.94[101] -1.16[102] -0.34[103]
16 PPIP5K2 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 -0.77[104] 1.07[105] 1.14[106] 0.71[107] 0.89[108] 1.40[109]
17 IP6K1 Inositol hexakisphosphate kinase 1 [110] 0.99[111] 0.68[112] 1.27[113] 0.50[114] 1.64[115] 0.79[116]
18 OCRL Inositol polyphosphate 5-phosphatase OCRL-1 [117] 1.31[118] 1.40[119] 1.97[120] 1.49[121] 1.71[122] 0.43[123]
19 IPPK Inositol-pentakisphosphate 2-kinase [124] -0.62[125] -0.80[126] -1.39[127] -0.64[128] 0.16[129] -0.88[130]
20 ITPKA Inositol-trisphosphate 3-kinase A [131] 0.94[132] 0.82[133] -0.27[134] -3.26[135] -1.26[136] -4.95[137]
21 IP6K3 Inositol hexakisphosphate kinase 3 [138] -3.02[139] -6.45[140] -9.84[141] -4.74[142] 0.40[143] -0.81[144]
22 PLCD1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 [145] -0.75[146] -0.09[147] 0.04[148] -1.98[149] -1.01[150] -0.13[151]
23 PLCB3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [152] 1.25[153] 0.51[154] 1.08[155] 1.80[156] 1.75[157] -0.11[158]
24 PLCD3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 [159] 3.03[160] 1.40[161] -1.29[162] 3.03[163] 1.69[164] -3.36[165]
25 INPP5B Type II inositol 1,4,5-trisphosphate 5-phosphatase [166] -0.08[167] -0.18[168] 0.14[169] -1.05[170] 0.53[171] 1.76[172]
26 ISYNA1 Inositol-3-phosphate synthase 1 [173] 2.67[174] 2.67[175] 2.13[176] -3.14[177] 0.94[178] 0.00[179]
27 INPP5D Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 [180] 3.10[181] 3.26[182] -6.82[183] -6.57[184] -3.32[185] 0.44[186]
28 PLCB1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [187] 2.03[188] 3.44[189] 2.97[190] -0.13[191] 0.66[192] 1.65[193]
29 PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 -2.04[194] -8.00[195] -0.45[196] -3.64[197] -2.19[198] 1.88[199]
30 MTMR9 Myotubularin-related protein 9 [200] 0.26[201] 0.47[202] 0.37[203] 0.33[204] 1.68[205] 2.04[206]
31 PPIP5K1 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 1.56[207] 1.84[208] 1.59[209] 2.24[210] 1.88[211] 1.63[212]
32 INPP4A Type I inositol 3,4-bisphosphate 4-phosphatase [213] 1.61[214] 1.42[215] 2.18[216] 2.63[217] 2.62[218] 2.15[219]
33 PLCB2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [220] -2.38[221] -7.38[222] -9.12[223] -2.84[224] -3.26[225] 1.39[226]
34 SYNJ1 Synaptojanin-1 [227] 0.64[228] 0.75[229] 1.51[230] 2.24[231] 2.66[232] 2.46[233]
35 PLCH2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 [234] 1.00[235] 2.64[236] -5.46[237] -6.55[238] -6.11[239] 0.92[240]
36 PLCH1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 [241] 1.04[242] 0.76[243] 2.52[244] 1.70[245] -1.84[246] -0.38[247]
37 ITPKB Inositol-trisphosphate 3-kinase B [248] -4.98[249] -6.65[250] -6.10[251] 2.60[252] 3.50[253] 3.28[254]
38 PLD4 Phospholipase D4 [255] -5.43[256] [257] [258] -7.62[259] -3.40[260] -1.42[261]
39 NUDT11 Diphosphoinositol polyphosphate phosphohydrolase 3-beta [262] [263] [264] -7.07[265] 0.49[266] 2.30[267] -3.33[268]
40 MTMR7 Myotubularin-related protein 7 [269] 0.19[270] 2.22[271] 3.02[272] 0.84[273] 1.17[274] 2.41[275]
41 PLCE1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 -1.37[276] -2.58[277] 4.94[278] 5.11[279] 1.74[280] 2.09[281]
42 NUDT10 Diphosphoinositol polyphosphate phosphohydrolase 3-alpha [282] [283] -6.19[284] [285] -1.88[286] -0.30[287] 1.62[288]
43 PLCD4 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 [289] 0.99[290] 0.76[291] 1.57[292] 4.11[293] 3.05[294] 0.63[295]
44 INPP5J Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A [296] 3.12[297] 0.73[298] 4.41[299] 2.41[300] 4.18[301] -1.29[302]
45 PLCB4 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 [303] -0.50[304] -0.88[305] 0.23[306] 8.72[307] 6.74[308] 2.95[309]
46 INPP4B Type II inositol 3,4-bisphosphate 4-phosphatase [310] -0.67[311] -1.82[312] [313] 0.91[314] 8.37[315] 7.16[316]
47 PLCZ1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 [317] [318] [319] [320] [321] [322] [323]
48 MIOX Inositol oxygenase [324] [325] [326] [327] [328] [329] [330]
[1]
ref_hepatocyte CALM1
Mean 29.2
Standard deviation 11
Values 17 40 21 28 40
[2]
HepG2 CALM1
Mean 67.9
Standard deviation 4.3
Values 65 71
[3]
HepG2.C3A CALM1
Mean 62
Standard deviation 16
Values 51 73
[4]
HuH.7 CALM1
Mean 81.9
Standard deviation 15
Values 90 64 92
[5]
SNU475 CALM1
Mean 160
Standard deviation 24
Values 1.8e+02 1.4e+02
[6]
THLE CALM1
Mean 109
Standard deviation 13
Values 1e+02 1.2e+02
[7]
liver CALM1
Mean 127
Standard deviation 70
Values 2.1e+02 80 1.7e+02 57
[8]
ref_hepatocyte IMPA2
Mean 19
Standard deviation 10
Values 27 9.1 7.1 25 28
[9]
HepG2 IMPA2
Mean 15.8
Standard deviation 3.8
Values 18 13
[10]
HepG2.C3A IMPA2
Mean 33.4
Standard deviation 5.2
Values 30 37
[11]
HuH.7 IMPA2
Mean 57
Standard deviation 21
Values 61 34 75
[12]
SNU475 IMPA2
Mean 22.3
Standard deviation 2.6
Values 24 21
[13]
THLE IMPA2
Mean 5.3
Standard deviation 0.48
Values 5.6 5
[14]
liver IMPA2
Mean 17.4
Standard deviation 6.3
Values 24 11 21 13
[15]
ref_hepatocyte NUDT3
Mean 15.3
Standard deviation 13
Values 35 23 8.7 5.7 4.1
[16]
HepG2 NUDT3
Mean 24.4
Standard deviation 3
Values 26 22
[17]
HepG2.C3A NUDT3
Mean 17.3
Standard deviation 3.5
Values 15 20
[18]
HuH.7 NUDT3
Mean 10.1
Standard deviation 2.4
Values 12 7.5 11
[19]
SNU475 NUDT3
Mean 11.9
Standard deviation 1.3
Values 13 11
[20]
THLE NUDT3
Mean 8.94
Standard deviation 2.2
Values 7.4 11
[21]
liver NUDT3
Mean 15.7
Standard deviation 1.7
Values 17 16 17 13
[22]
ref_hepatocyte NUDT4
Mean 13.5
Standard deviation 5.1
Values 21 17 12 8.2 10
[23]
HepG2 NUDT4
Mean 2.12
Standard deviation 0.61
Values 1.7 2.6
[24]
HepG2.C3A NUDT4
Mean 1.63
Standard deviation 0.12
Values 1.7 1.5
[25]
HuH.7 NUDT4
Mean 1.93
Standard deviation 0.56
Values 1.3 2.4 2.1
[26]
SNU475 NUDT4
Mean 0.883
Standard deviation 0.28
Values 0.68 1.1
[27]
THLE NUDT4
Mean 0.705
Standard deviation 0.24
Values 0.54 0.87
[28]
liver NUDT4
Mean 1.03
Standard deviation 0.14
Values 1.1 1.1 0.82 1.1
[29]
ref_hepatocyte IP6K2
Mean 11.1
Standard deviation 5.7
Values 21 7.9 8 8.3 10
[30]
HepG2 IP6K2
Mean 33.5
Standard deviation 1.9
Values 35 32
[31]
HepG2.C3A IP6K2
Mean 42.6
Standard deviation 0.79
Values 43 42
[32]
HuH.7 IP6K2
Mean 56.2
Standard deviation 11
Values 46 55 67
[33]
SNU475 IP6K2
Mean 15.3
Standard deviation 0.2
Values 15 15
[34]
THLE IP6K2
Mean 27.8
Standard deviation 2.2
Values 29 26
[35]
liver IP6K2
Mean 14.2
Standard deviation 9.2
Values 25 7 18 6.2
[36]
ref_hepatocyte ITPK1
Mean 9.61
Standard deviation 4.1
Values 4.5 7 9.1 13 14
[37]
HepG2 ITPK1
Mean 51.3
Standard deviation 10
Values 59 44
[38]
HepG2.C3A ITPK1
Mean 22.1
Standard deviation 0.46
Values 22 22
[39]
HuH.7 ITPK1
Mean 8.02
Standard deviation 1.6
Values 9.6 6.4 8
[40]
SNU475 ITPK1
Mean 18
Standard deviation 3
Values 20 16
[41]
THLE ITPK1
Mean 21
Standard deviation 2.6
Values 19 23
[42]
liver ITPK1
Mean 16.9
Standard deviation 6.6
Values 14 11 16 26
[43]
ref_hepatocyte ITPKC
Mean 8.56
Standard deviation 10
Values 3.9 5.3 27 5 2.1
[44]
HepG2 ITPKC
Mean 11.8
Standard deviation 2.1
Values 13 10
[45]
HepG2.C3A ITPKC
Mean 14.6
Standard deviation 5.3
Values 18 11
[46]
HuH.7 ITPKC
Mean 12.5
Standard deviation 2.6
Values 10 15 12
[47]
SNU475 ITPKC
Mean 5.88
Standard deviation 0.4
Values 6.2 5.6
[48]
THLE ITPKC
Mean 8.52
Standard deviation 0.17
Values 8.4 8.6
[49]
liver ITPKC
Mean 7.64
Standard deviation 1.2
Values 5.9 8 7.9 8.7
[50]
ref_hepatocyte MINPP1
Mean 7.77
Standard deviation 5.6
Values 6.1 2.9 3.1 11 16
[51]
HepG2 MINPP1
Mean 23.2
Standard deviation 5.7
Values 19 27
[52]
HepG2.C3A MINPP1
Mean 39.3
Standard deviation 1.8
Values 38 41
[53]
HuH.7 MINPP1
Mean 24
Standard deviation 2.4
Values 24 22 27
[54]
SNU475 MINPP1
Mean 9.31
Standard deviation 0.47
Values 9.6 9
[55]
THLE MINPP1
Mean 22.3
Standard deviation 1.9
Values 21 24
[56]
liver MINPP1
Mean 15.6
Standard deviation 4.4
Values 22 13 14 14
[57]
ref_hepatocyte INPP5A
Mean 7.74
Standard deviation 7.8
Values 21 8.6 1.6 3.5 4.1
[58]
HepG2 INPP5A
Mean 20.9
Standard deviation 4
Values 18 24
[59]
HepG2.C3A INPP5A
Mean 24.8
Standard deviation 3
Values 23 27
[60]
HuH.7 INPP5A
Mean 11.5
Standard deviation 0.85
Values 12 11 11
[61]
SNU475 INPP5A
Mean 4.22
Standard deviation 0.61
Values 4.7 3.8
[62]
THLE INPP5A
Mean 6.45
Standard deviation 0.31
Values 6.2 6.7
[63]
liver INPP5A
Mean 6.89
Standard deviation 2.6
Values 7 7.9 3.3 9.4
[64]
ref_hepatocyte PTEN
Mean 6.57
Standard deviation 2.4
Values 4.2 5.9 5.2 7 11
[65]
HepG2 PTEN
Mean 9.98
Standard deviation 2.3
Values 8.4 12
[66]
HepG2.C3A PTEN
Mean 23.3
Standard deviation 3.3
Values 26 21
[67]
HuH.7 PTEN
Mean 25.7
Standard deviation 12
Values 19 39 19
[68]
SNU475 PTEN
Mean 8.16
Standard deviation 1.8
Values 9.4 6.9
[69]
THLE PTEN
Mean 21.8
Standard deviation 0.98
Values 22 21
[70]
liver PTEN
Mean 52
Standard deviation 9.3
Values 61 55 39 53
[71]
ref_hepatocyte INPP1
Mean 6.49
Standard deviation 3.7
Values 1.2 8.5 10 8.5 4.2
[72]
HepG2 INPP1
Mean 6.42
Standard deviation 0.55
Values 6.8 6
[73]
HepG2.C3A INPP1
Mean 18.5
Standard deviation 2.7
Values 20 17
[74]
HuH.7 INPP1
Mean 13.5
Standard deviation 1.7
Values 14 12 15
[75]
SNU475 INPP1
Mean 3.83
Standard deviation 0.24
Values 3.7 4
[76]
THLE INPP1
Mean 11.4
Standard deviation 0.22
Values 11 12
[77]
liver INPP1
Mean 5.8
Standard deviation 3.5
Values 9.7 2.7 7.9 2.9
[78]
ref_hepatocyte INPPL1
Mean 3.88
Standard deviation 1.7
Values 2 2.9 6.2 5.2 3.2
[79]
HepG2 INPPL1
Mean 37.7
Standard deviation 3.4
Values 40 35
[80]
HepG2.C3A INPPL1
Mean 20.1
Standard deviation 6.4
Values 25 16
[81]
HuH.7 INPPL1
Mean 32.5
Standard deviation 0.66
Values 33 32 32
[82]
SNU475 INPPL1
Mean 71.4
Standard deviation 11
Values 79 63
[83]
THLE INPPL1
Mean 48.7
Standard deviation 0.9
Values 49 48
[84]
liver INPPL1
Mean 10.7
Standard deviation 5.3
Values 9.6 12 4.4 17
[85]
ref_hepatocyte IMPA1
Mean 3.72
Standard deviation 1.7
Values 3.6 6.6 2.4 2.5 3.4
[86]
HepG2 IMPA1
Mean 8.73
Standard deviation 3.4
Values 6.3 11
[87]
HepG2.C3A IMPA1
Mean 16.3
Standard deviation 4.4
Values 13 19
[88]
HuH.7 IMPA1
Mean 13.9
Standard deviation 1.9
Values 14 12 16
[89]
SNU475 IMPA1
Mean 17.1
Standard deviation 2.7
Values 19 15
[90]
THLE IMPA1
Mean 15
Standard deviation 2
Values 14 16
[91]
liver IMPA1
Mean 15.5
Standard deviation 2.5
Values 18 15 12 17
[92]
ref_hepatocyte PLCG1
Mean 3.54
Standard deviation 4.5
Values 11 2.4 1.7 0.91 1.2
[93]
HepG2 PLCG1
Mean 87.8
Standard deviation 4.3
Values 91 85
[94]
HepG2.C3A PLCG1
Mean 60.1
Standard deviation 10
Values 67 53
[95]
HuH.7 PLCG1
Mean 36.2
Standard deviation 5.9
Values 40 30 39
[96]
SNU475 PLCG1
Mean 45.9
Standard deviation 1.9
Values 47 45
[97]
THLE PLCG1
Mean 36.2
Standard deviation 0.92
Values 36 37
[98]
liver PLCG1
Mean 6.36
Standard deviation 4.9
Values 2.3 8.9 2.2 12
[99]
ref_hepatocyte IPMK
Mean 3.46
Standard deviation 1.8
Values 4.3 4.4 1.4 1.8 5.4
[100]
HepG2 IPMK
Mean 4.63
Standard deviation 2.8
Values 2.7 6.6
[101]
HepG2.C3A IPMK
Mean 12.5
Standard deviation 2.1
Values 11 14
[102]
HuH.7 IPMK
Mean 17.2
Standard deviation 6.9
Values 16 25 11
[103]
SNU475 IPMK
Mean 6.22
Standard deviation 0.78
Values 5.7 6.8
[104]
THLE IPMK
Mean 4.86
Standard deviation 0.41
Values 5.2 4.6
[105]
liver IPMK
Mean 6.97
Standard deviation 2
Values 4.7 9.4 6.2 7.6
[106]
ref_hepatocyte PPIP5K2
Mean 3.26
Standard deviation 1.5
Values 4.5 4.6 1.9 1.4 3.9
[107]
HepG2 PPIP5K2
Mean 7.1
Standard deviation 3.6
Values 4.5 9.7
[108]
HepG2.C3A PPIP5K2
Mean 26.4
Standard deviation 8.5
Values 20 32
[109]
HuH.7 PPIP5K2
Mean 24.8
Standard deviation 3.5
Values 29 22 24
[110]
SNU475 PPIP5K2
Mean 18.4
Standard deviation 4.2
Values 21 15
[111]
THLE PPIP5K2
Mean 18.9
Standard deviation 2.3
Values 21 17
[112]
liver PPIP5K2
Mean 21.9
Standard deviation 3.7
Values 20 27 21 19
[113]
ref_hepatocyte IP6K1
Mean 2.97
Standard deviation 1.3
Values 2.3 2.8 5 3.3 1.6
[114]
HepG2 IP6K1
Mean 22
Standard deviation 0.47
Values 22 22
[115]
HepG2.C3A IP6K1
Mean 18.4
Standard deviation 2.5
Values 20 17
[116]
HuH.7 IP6K1
Mean 24.8
Standard deviation 2.7
Values 27 25 22
[117]
SNU475 IP6K1
Mean 14.5
Standard deviation 0.0032
Values 15 15
[118]
THLE IP6K1
Mean 29.2
Standard deviation 5.1
Values 26 33
[119]
liver IP6K1
Mean 13.1
Standard deviation 2
Values 10 14 14 15
[120]
ref_hepatocyte OCRL
Mean 2.8
Standard deviation 2.1
Values 6.4 2.6 1.7 1.7 1.6
[121]
HepG2 OCRL
Mean 25.8
Standard deviation 4.1
Values 23 29
[122]
HepG2.C3A OCRL
Mean 28.5
Standard deviation 3.8
Values 31 26
[123]
HuH.7 OCRL
Mean 38
Standard deviation 8.2
Values 36 47 31
[124]
SNU475 OCRL
Mean 27.1
Standard deviation 4.9
Values 31 24
[125]
THLE OCRL
Mean 28.8
Standard deviation 1
Values 28 29
[126]
liver OCRL
Mean 9.56
Standard deviation 3.8
Values 6.6 12 6.1 13
[127]
ref_hepatocyte IPPK
Mean 2.74
Standard deviation 2.5
Values 4.8 6 1 0.94 0.92
[128]
HepG2 IPPK
Mean 6.65
Standard deviation 0.28
Values 6.5 6.9
[129]
HepG2.C3A IPPK
Mean 6.08
Standard deviation 1.5
Values 5.1 7.1
[130]
HuH.7 IPPK
Mean 3.62
Standard deviation 0.65
Values 3.9 2.9 4.1
[131]
SNU475 IPPK
Mean 6.05
Standard deviation 0.4
Values 5.8 6.3
[132]
THLE IPPK
Mean 9.63
Standard deviation 1.4
Values 8.6 11
[133]
liver IPPK
Mean 3.8
Standard deviation 1.6
Values 1.6 5.5 4 4.1
[134]
ref_hepatocyte ITPKA
Mean 2.5
Standard deviation 4.1
Values 9.7 0.45 0.56 1.6 0.18
[135]
HepG2 ITPKA
Mean 17.8
Standard deviation 1.2
Values 19 17
[136]
HepG2.C3A ITPKA
Mean 17.1
Standard deviation 0.59
Values 18 17
[137]
HuH.7 ITPKA
Mean 7.14
Standard deviation 2.3
Values 7.6 4.6 9.2
[138]
SNU475 ITPKA
Mean 0.899
Standard deviation 0.26
Values 0.71 1.1
[139]
THLE ITPKA
Mean 3.28
Standard deviation 0.43
Values 3.6 3
[140]
liver ITPKA
Mean 0.205
Standard deviation 0.089
Values 0.28 0.16 0.1 0.28
[141]
ref_hepatocyte IP6K3
Mean 2.42
Standard deviation 2.8
Values 0.35 0.43 4.1 6.6 0.62
[142]
HepG2 IP6K3
Mean 1.11
Standard deviation 0.92
Values 1.8 0.46
[143]
HepG2.C3A IP6K3
Mean 0.108
Standard deviation 0.015
Values 0.097 0.12
[144]
HuH.7 IP6K3
Mean 0.00915
Standard deviation 0.0097
Values 0.0082 0.019 0
[145]
SNU475 IP6K3
Mean 0.312
Standard deviation 0.061
Values 0.27 0.35
[146]
THLE IP6K3
Mean 10
Standard deviation 2.2
Values 12 8.5
[147]
liver IP6K3
Mean 3.51
Standard deviation 2.7
Values 4.3 1.1 1.7 6.9
[148]
ref_hepatocyte PLCD1
Mean 2.06
Standard deviation 0.9
Values 2.2 0.98 3.5 1.9 1.8
[149]
HepG2 PLCD1
Mean 4.58
Standard deviation 0.52
Values 5 4.2
[150]
HepG2.C3A PLCD1
Mean 7.51
Standard deviation 2.9
Values 9.6 5.4
[151]
HuH.7 PLCD1
Mean 7.35
Standard deviation 0.78
Values 8 7.5 6.5
[152]
SNU475 PLCD1
Mean 1.79
Standard deviation 0.4
Values 2.1 1.5
[153]
THLE PLCD1
Mean 3.21
Standard deviation 0.4
Values 3.5 2.9
[154]
liver PLCD1
Mean 4.81
Standard deviation 0.83
Values 4.1 4.1 5.8 5.2
[155]
ref_hepatocyte PLCB3
Mean 1.72
Standard deviation 1
Values 3.3 2 1.6 0.84 0.87
[156]
HepG2 PLCB3
Mean 15.2
Standard deviation 2.5
Values 13 17
[157]
HepG2.C3A PLCB3
Mean 9.48
Standard deviation 0.28
Values 9.3 9.7
[158]
HuH.7 PLCB3
Mean 12.5
Standard deviation 4.9
Values 15 6.9 16
[159]
SNU475 PLCB3
Mean 20.7
Standard deviation 4.4
Values 24 18
[160]
THLE PLCB3
Mean 18.1
Standard deviation 1.4
Values 17 19
[161]
liver PLCB3
Mean 4.04
Standard deviation 2.9
Values 1.7 5.4 1.5 7.5
[162]
ref_hepatocyte PLCD3
Mean 1.67
Standard deviation 1.4
Values 2.1 3.5 2.1 0.25 0.43
[163]
HepG2 PLCD3
Mean 51
Standard deviation 3.1
Values 53 49
[164]
HepG2.C3A PLCD3
Mean 17
Standard deviation 2
Values 18 16
[165]
HuH.7 PLCD3
Mean 2.36
Standard deviation 0.27
Values 2.4 2.1 2.6
[166]
SNU475 PLCD3
Mean 47.1
Standard deviation 10
Values 54 40
[167]
THLE PLCD3
Mean 17
Standard deviation 1.8
Values 16 18
[168]
liver PLCD3
Mean 0.414
Standard deviation 0.22
Values 0.4 0.4 0.15 0.7
[169]
ref_hepatocyte INPP5B
Mean 1.53
Standard deviation 0.74
Values 1.6 1.1 0.51 2.2 2.2
[170]
HepG2 INPP5B
Mean 5.37
Standard deviation 0.56
Values 5.8 5
[171]
HepG2.C3A INPP5B
Mean 5.2
Standard deviation 0.98
Values 5.9 4.5
[172]
HuH.7 INPP5B
Mean 5.83
Standard deviation 1.5
Values 5.5 4.5 7.5
[173]
SNU475 INPP5B
Mean 2.53
Standard deviation 0.2
Values 2.4 2.7
[174]
THLE INPP5B
Mean 6.92
Standard deviation 0.46
Values 6.6 7.2
[175]
liver INPP5B
Mean 13.1
Standard deviation 2.2
Values 13 16 10 13
[176]
ref_hepatocyte ISYNA1
Mean 1.44
Standard deviation 2
Values 5 0.36 0.64 0.62 0.55
[177]
HepG2 ISYNA1
Mean 34.3
Standard deviation 13
Values 44 25
[178]
HepG2.C3A ISYNA1
Mean 35.5
Standard deviation 8.3
Values 41 30
[179]
HuH.7 ISYNA1
Mean 21.8
Standard deviation 7.2
Values 26 14 26
[180]
SNU475 ISYNA1
Mean 0.563
Standard deviation 0.022
Values 0.55 0.58
[181]
THLE ISYNA1
Mean 8.72
Standard deviation 1.7
Values 9.9 7.5
[182]
liver ISYNA1
Mean 3.68
Standard deviation 3.1
Values 8.2 1.1 2.9 2.5
[183]
ref_hepatocyte INPP5D
Mean 1.08
Standard deviation 1.6
Values 3.8 0.096 0.065 0.29 1.1
[184]
HepG2 INPP5D
Mean 34.6
Standard deviation 2.7
Values 36 33
[185]
HepG2.C3A INPP5D
Mean 40.3
Standard deviation 7.8
Values 46 35
[186]
HuH.7 INPP5D
Mean 0.0331
Standard deviation 0.0052
Values 0.033 0.039 0.028
[187]
SNU475 INPP5D
Mean 0.0393
Standard deviation 0.016
Values 0.028 0.051
[188]
THLE INPP5D
Mean 0.34
Standard deviation 0.1
Values 0.41 0.27
[189]
liver INPP5D
Mean 3.74
Standard deviation 0.43
Values 3.6 3.5 3.5 4.4
[190]
ref_hepatocyte PLCB1
Mean 0.993
Standard deviation 1.3
Values 3.2 0.71 0.37 0.15 0.52
[191]
HepG2 PLCB1
Mean 15.2
Standard deviation 2.6
Values 13 17
[192]
HepG2.C3A PLCB1
Mean 41.8
Standard deviation 4.5
Values 45 39
[193]
HuH.7 PLCB1
Mean 26.9
Standard deviation 8.9
Values 26 36 19
[194]
SNU475 PLCB1
Mean 3.13
Standard deviation 0.39
Values 3.4 2.9
[195]
THLE PLCB1
Mean 4.93
Standard deviation 0.69
Values 5.4 4.4
[196]
liver PLCB1
Mean 7.93
Standard deviation 2.5
Values 8.6 11 6 6
[197]
ref_hepatocyte PLCG2
Mean 0.967
Standard deviation 0.77
Values 0 0.93 0.46 1.9 1.6
[198]
HepG2 PLCG2
Mean 0.879
Standard deviation 0.82
Values 1.5 0.3
[199]
HepG2.C3A PLCG2
Mean 0.0146
Standard deviation 0.021
Values 0.029 0
[200]
HuH.7 PLCG2
Mean 2.44
Standard deviation 1.1
Values 1.9 3.7 1.8
[201]
SNU475 PLCG2
Mean 0.267
Standard deviation 0.089
Values 0.2 0.33
[202]
THLE PLCG2
Mean 0.664
Standard deviation 0.061
Values 0.62 0.71
[203]
liver PLCG2
Mean 9.03
Standard deviation 2.5
Values 12 10 5.7 8.7
[204]
ref_hepatocyte MTMR9
Mean 0.96
Standard deviation 0.48
Values 0.85 1.7 1.1 0.59 0.54
[205]
HepG2 MTMR9
Mean 4.28
Standard deviation 0.48
Values 3.9 4.6
[206]
HepG2.C3A MTMR9
Mean 5.16
Standard deviation 0.36
Values 4.9 5.4
[207]
HuH.7 MTMR9
Mean 4.3
Standard deviation 0.84
Values 5.3 3.8 3.9
[208]
SNU475 MTMR9
Mean 4.17
Standard deviation 0.23
Values 4.3 4
[209]
THLE MTMR9
Mean 9.65
Standard deviation 0.37
Values 9.9 9.4
[210]
liver MTMR9
Mean 10
Standard deviation 3.7
Values 6.9 14 7 12
[211]
ref_hepatocyte PPIP5K1
Mean 0.861
Standard deviation 0.24
Values 1.2 0.68 0.77 1 0.63
[212]
HepG2 PPIP5K1
Mean 9.48
Standard deviation 0.37
Values 9.2 9.7
[213]
HepG2.C3A PPIP5K1
Mean 12
Standard deviation 0.86
Values 11 13
[214]
HuH.7 PPIP5K1
Mean 8.96
Standard deviation 2.2
Values 11 7.3 8.1
[215]
SNU475 PPIP5K1
Mean 14
Standard deviation 2.2
Values 16 12
[216]
THLE PPIP5K1
Mean 9.99
Standard deviation 0.22
Values 10 9.8
[217]
liver PPIP5K1
Mean 6.77
Standard deviation 3.9
Values 2.9 12 5.6 6.5
[218]
ref_hepatocyte INPP4A
Mean 0.757
Standard deviation 0.47
Values 1.5 0.91 0.3 0.38 0.74
[219]
HepG2 INPP4A
Mean 8.61
Standard deviation 0.94
Values 7.9 9.3
[220]
HepG2.C3A INPP4A
Mean 7.83
Standard deviation 0.93
Values 8.5 7.2
[221]
HuH.7 INPP4A
Mean 11.9
Standard deviation 2.1
Values 14 11 11
[222]
SNU475 INPP4A
Mean 16.1
Standard deviation 5.3
Values 20 12
[223]
THLE INPP4A
Mean 14.6
Standard deviation 0.67
Values 15 14
[224]
liver INPP4A
Mean 8.57
Standard deviation 2.8
Values 5.9 12 6.5 10
[225]
ref_hepatocyte PLCB2
Mean 0.44
Standard deviation 0.47
Values 0 0.049 0.42 0.57 1.2
[226]
HepG2 PLCB2
Mean 0.316
Standard deviation 0.31
Values 0.53 0.099
[227]
HepG2.C3A PLCB2
Mean 0.0102
Standard deviation 0.00071
Values 0.0097 0.011
[228]
HuH.7 PLCB2
Mean 0.00273
Standard deviation 0.0047
Values 0.0082 0 0
[229]
SNU475 PLCB2
Mean 0.211
Standard deviation 0.062
Values 0.26 0.17
[230]
THLE PLCB2
Mean 0.145
Standard deviation 0.029
Values 0.12 0.16
[231]
liver PLCB2
Mean 2.94
Standard deviation 1.6
Values 1.8 3.5 1.5 4.9
[232]
ref_hepatocyte SYNJ1
Mean 0.438
Standard deviation 0.073
Values 0.45 0.45 0.38 0.36 0.54
[233]
HepG2 SYNJ1
Mean 2.55
Standard deviation 1.1
Values 1.8 3.3
[234]
HepG2.C3A SYNJ1
Mean 2.86
Standard deviation 0.44
Values 2.5 3.2
[235]
HuH.7 SYNJ1
Mean 4.3
Standard deviation 0.6
Values 4.8 4.5 3.6
[236]
SNU475 SYNJ1
Mean 7.11
Standard deviation 0.46
Values 6.8 7.4
[237]
THLE SYNJ1
Mean 8.68
Standard deviation 0.99
Values 8 9.4
[238]
liver SYNJ1
Mean 6.13
Standard deviation 1.1
Values 5.7 7.8 5.2 5.9
[239]
ref_hepatocyte PLCH2
Mean 0.189
Standard deviation 0.15
Values 0.096 0 0.31 0.38 0.16
[240]
HepG2 PLCH2
Mean 1.41
Standard deviation 0.47
Values 1.7 1.1
[241]
HepG2.C3A PLCH2
Mean 4.55
Standard deviation 1.7
Values 5.7 3.4
[242]
HuH.7 PLCH2
Mean 0.0148
Standard deviation 0.013
Values 0 0.026 0.019
[243]
SNU475 PLCH2
Mean 0.00696
Standard deviation 0.0098
Values 0.014 0
[244]
THLE PLCH2
Mean 0.00858
Standard deviation 0.0046
Values 0.012 0.0053
[245]
liver PLCH2
Mean 0.912
Standard deviation 1
Values 0 2.2 0.18 1.3
[246]
ref_hepatocyte PLCH1
Mean 0.163
Standard deviation 0.21
Values 0.51 0.21 0.033 0.052 0.0081
[247]
HepG2 PLCH1
Mean 1.25
Standard deviation 0.31
Values 1 1.5
[248]
HepG2.C3A PLCH1
Mean 1.07
Standard deviation 0.66
Values 0.6 1.5
[249]
HuH.7 PLCH1
Mean 3.23
Standard deviation 1
Values 4.2 2.2 3.3
[250]
SNU475 PLCH1
Mean 1.82
Standard deviation 1
Values 2.6 1.1
[251]
THLE PLCH1
Mean 0.143
Standard deviation 0.061
Values 0.1 0.19
[252]
liver PLCH1
Mean 0.319
Standard deviation 0.062
Values 0.28 0.3 0.28 0.41
[253]
ref_hepatocyte ITPKB
Mean 0.139
Standard deviation 0.12
Values 0 0.018 0.29 0.18 0.21
[254]
HepG2 ITPKB
Mean 0.0165
Standard deviation 0.017
Values 0.029 0.0043
[255]
HepG2.C3A ITPKB
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[256]
HuH.7 ITPKB
Mean 0.00701
Standard deviation 0.0065
Values 0.0082 0.013 0
[257]
SNU475 ITPKB
Mean 2.9
Standard deviation 0.2
Values 2.8 3
[258]
THLE ITPKB
Mean 4.96
Standard deviation 0.15
Values 4.9 5.1
[259]
liver ITPKB
Mean 3.43
Standard deviation 2.1
Values 1.7 4.2 1.8 6
[260]
ref_hepatocyte PLD4
Mean 0.133
Standard deviation 0.26
Values 0 0 0 0.078 0.59
[261]
HepG2 PLD4
Mean 0.0115
Standard deviation 0.016
Values 0.023 0
[262]
HepG2.C3A PLD4
Mean 0
Standard deviation 0
Values 0 0
[263]
HuH.7 PLD4
Mean 0
Standard deviation 0
Values 0 0 0
[264]
SNU475 PLD4
Mean 0.00232
Standard deviation 0.0033
Values 0.0046 0
[265]
THLE PLD4
Mean 0.0393
Standard deviation 0.003
Values 0.041 0.037
[266]
liver PLD4
Mean 0.126
Standard deviation 0.083
Values 0.19 0.071 0.21 0.04
[267]
ref_hepatocyte NUDT11
Mean 0.106
Standard deviation 0.1
Values 0 0.2 0.11 0 0.22
[268]
HepG2 NUDT11
Mean 0
Standard deviation 0
Values 0 0
[269]
HepG2.C3A NUDT11
Mean 0
Standard deviation 0
Values 0 0
[270]
HuH.7 NUDT11
Mean 0.00273
Standard deviation 0.0047
Values 0.0082 0 0
[271]
SNU475 NUDT11
Mean 0.512
Standard deviation 0.042
Values 0.48 0.54
[272]
THLE NUDT11
Mean 1.64
Standard deviation 0.79
Values 1.1 2.2
[273]
liver NUDT11
Mean 0.0269
Standard deviation 0.024
Values 0 0.043 0.051 0.013
[274]
ref_hepatocyte MTMR7
Mean 0.103
Standard deviation 0.13
Values 0 0 0.32 0.1 0.098
[275]
HepG2 MTMR7
Mean 0.439
Standard deviation 0.07
Values 0.39 0.49
[276]
HepG2.C3A MTMR7
Mean 1.86
Standard deviation 0.4
Values 2.1 1.6
[277]
HuH.7 MTMR7
Mean 2.89
Standard deviation 0.92
Values 2.3 3.9 2.5
[278]
SNU475 MTMR7
Mean 0.637
Standard deviation 0.074
Values 0.58 0.69
[279]
THLE MTMR7
Mean 0.729
Standard deviation 0.25
Values 0.91 0.55
[280]
liver MTMR7
Mean 1.4
Standard deviation 0.5
Values 1.1 1.7 0.9 1.9
[281]
ref_hepatocyte PLCE1
Mean 0.102
Standard deviation 0.18
Values 0 0.42 0.033 0.017 0.041
[282]
HepG2 PLCE1
Mean 0.147
Standard deviation 0.078
Values 0.092 0.2
[283]
HepG2.C3A PLCE1
Mean 0.0662
Standard deviation 0.0026
Values 0.068 0.064
[284]
HuH.7 PLCE1
Mean 10.9
Standard deviation 3.4
Values 12 13 6.9
[285]
SNU475 PLCE1
Mean 12.1
Standard deviation 4.5
Values 15 9
[286]
THLE PLCE1
Mean 1.07
Standard deviation 0.3
Values 1.3 0.86
[287]
liver PLCE1
Mean 1.11
Standard deviation 0.7
Values 0.28 1.6 0.8 1.8
[288]
ref_hepatocyte NUDT10
Mean 0.0915
Standard deviation 0.14
Values 0 0 0.33 0.069 0.057
[289]
HepG2 NUDT10
Mean 0
Standard deviation 0
Values 0 0
[290]
HepG2.C3A NUDT10
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[291]
HuH.7 NUDT10
Mean 0
Standard deviation 0
Values 0 0 0
[292]
SNU475 NUDT10
Mean 0.0857
Standard deviation 0.11
Values 0.0093 0.16
[293]
THLE NUDT10
Mean 0.234
Standard deviation 0.11
Values 0.15 0.31
[294]
liver NUDT10
Mean 0.716
Standard deviation 0.11
Values 0.87 0.6 0.72 0.68
[295]
ref_hepatocyte PLCD4
Mean 0.0778
Standard deviation 0.11
Values 0 0 0.049 0.26 0.081
[296]
HepG2 PLCD4
Mean 0.575
Standard deviation 0.091
Values 0.51 0.64
[297]
HepG2.C3A PLCD4
Mean 0.509
Standard deviation 0.037
Values 0.53 0.48
[298]
HuH.7 PLCD4
Mean 0.796
Standard deviation 0.11
Values 0.9 0.68 0.81
[299]
SNU475 PLCD4
Mean 4.61
Standard deviation 1
Values 5.4 3.9
[300]
THLE PLCD4
Mean 2.03
Standard deviation 0.2
Values 2.2 1.9
[301]
liver PLCD4
Mean 0.306
Standard deviation 0.11
Values 0.26 0.46 0.21 0.3
[302]
ref_hepatocyte INPP5J
Mean 0.0311
Standard deviation 0.07
Values 0 0.16 0 0 0
[303]
HepG2 INPP5J
Mean 1
Standard deviation 0.062
Values 1 0.96
[304]
HepG2.C3A INPP5J
Mean 0.199
Standard deviation 0.14
Values 0.3 0.097
[305]
HuH.7 INPP5J
Mean 2.29
Standard deviation 1.3
Values 1.3 3.8 1.8
[306]
SNU475 INPP5J
Mean 0.567
Standard deviation 0.24
Values 0.39 0.74
[307]
THLE INPP5J
Mean 1.76
Standard deviation 0.51
Values 2.1 1.4
[308]
liver INPP5J
Mean 0.0323
Standard deviation 0.05
Values 0.024 0 0 0.11
[309]
ref_hepatocyte PLCB4
Mean 0.0125
Standard deviation 0.024
Values 0 0 0.054 0 0.0081
[310]
HepG2 PLCB4
Mean 0.0329
Standard deviation 0.014
Values 0.023 0.043
[311]
HepG2.C3A PLCB4
Mean 0.0263
Standard deviation 0.023
Values 0.0097 0.043
[312]
HuH.7 PLCB4
Mean 0.0507
Standard deviation 0.032
Values 0.082 0.051 0.019
[313]
SNU475 PLCB4
Mean 18.2
Standard deviation 5.5
Values 22 14
[314]
THLE PLCB4
Mean 4.19
Standard deviation 1.3
Values 5.1 3.2
[315]
liver PLCB4
Mean 0.246
Standard deviation 0.29
Values 0.094 0.1 0.1 0.69
[316]
ref_hepatocyte INPP4B
Mean 0.00488
Standard deviation 0.011
Values 0 0 0 0 0.024
[317]
HepG2 INPP4B
Mean 0.0114
Standard deviation 0.0081
Values 0.0057 0.017
[318]
HepG2.C3A INPP4B
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[319]
HuH.7 INPP4B
Mean 0
Standard deviation 0
Values 0 0 0
[320]
SNU475 INPP4B
Mean 0.0317
Standard deviation 0.0054
Values 0.028 0.035
[321]
THLE INPP4B
Mean 5.09
Standard deviation 0.62
Values 4.6 5.5
[322]
liver INPP4B
Mean 1.78
Standard deviation 1.2
Values 0.71 3.2 0.8 2.5
[323]
ref_hepatocyte PLCZ1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[324]
HepG2 PLCZ1
Mean 0
Standard deviation 0
Values 0 0
[325]
HepG2.C3A PLCZ1
Mean 0
Standard deviation 0
Values 0 0
[326]
HuH.7 PLCZ1
Mean 0.0563
Standard deviation 0.047
Values 0.041 0.11 0.019
[327]
SNU475 PLCZ1
Mean 0.28
Standard deviation 0.1
Values 0.35 0.21
[328]
THLE PLCZ1
Mean 0.00532
Standard deviation 0.0075
Values 0 0.011
[329]
liver PLCZ1
Mean 0.0724
Standard deviation 0.036
Values 0.071 0.11 0.026 0.079
[330]
ref_hepatocyte MIOX
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[331]
HepG2 MIOX
Mean 1.46
Standard deviation 0.12
Values 1.5 1.4
[332]
HepG2.C3A MIOX
Mean 7.26
Standard deviation 1.9
Values 8.6 5.9
[333]
HuH.7 MIOX
Mean 0.267
Standard deviation 0.11
Values 0.15 0.31 0.35
[334]
SNU475 MIOX
Mean 0.0076
Standard deviation 0.011
Values 0 0.015
[335]
THLE MIOX
Mean 0.0115
Standard deviation 0.0088
Values 0.018 0.0053
[336]
liver MIOX
Mean 0.00642
Standard deviation 0.013
Values 0 0 0.026 0