REACTOME_HYALURONAN_METABOLISM Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 HYAL1 Hyaluronidase-1 [1] -0.76[2] -0.58[3] -6.02[4] -9.17[5] -7.54[6] -1.18[7]
2 HEXB Beta-hexosaminidase subunit beta [8] -0.48[9] -0.94[10] -0.04[11] -0.70[12] -0.52[13] -1.29[14]
3 GUSB Beta-glucuronidase [15] -1.87[16] -1.63[17] -0.78[18] -0.84[19] -1.93[20] -0.75[21]
4 HEXA Beta-hexosaminidase subunit alpha [22] 1.18[23] 0.45[24] 0.49[25] 0.90[26] 0.24[27] -0.73[28]
5 CD44 CD44 antigen [29] -7.32[30] -8.89[31] -2.12[32] 1.80[33] 1.67[34] -2.27[35]
6 HYAL2 Hyaluronidase-2 [36] 2.07[37] 2.23[38] 1.45[39] -0.31[40] 0.07[41] 0.15[42]
7 HMMR Hyaluronan mediated motility receptor [43] -0.56[44] 2.44[45] 2.24[46] 1.47[47] 1.76[48] -2.63[49]
8 LYVE1 Lymphatic vessel endothelial hyaluronic acid receptor 1 [50] -0.45[51] -2.08[52] -10.44[53] -3.78[54] [55] 2.66[56]
9 ABCC5 Multidrug resistance-associated protein 5 [57] 2.30[58] 2.29[59] 2.28[60] 2.49[61] 1.95[62] 1.04[63]
10 HYAL3 Hyaluronidase-3 [64] 1.71[65] 0.71[66] 1.38[67] -0.81[68] -0.50[69] -1.95[70]
11 HAS3 Hyaluronan synthase 3 [71] -1.38[72] -0.41[73] -1.88[74] 0.74[75] -2.40[76] -2.11[77]
12 SLC9A1 Sodium/hydrogen exchanger 1 [78] 2.74[79] 1.59[80] 0.80[81] 4.16[82] 3.49[83] -0.25[84]
13 STAB2 Stabilin-2 [85] -3.92[86] -2.34[87] -2.96[88] -2.22[89] -3.60[90] 6.07[91]
14 HAS1 Hyaluronan synthase 1 [92] [93] [94] [95] [96] [97] [98]
15 HAS2 Hyaluronan synthase 2 [99] [100] [101] [102] [103] [104] [105]
16 CEMIP Cell migration-inducing and hyaluronan-binding protein [106] [107] [108] [109] [110] [111] [112]
17 CHP1 Calcineurin B homologous protein 1 [113] [114] [115] [116] [117] [118] [119]
[1]
ref_hepatocyte HYAL1
Mean 53.9
Standard deviation 39
Values 18 24 36 90 1e+02
[2]
HepG2 HYAL1
Mean 83.6
Standard deviation 4.4
Values 81 87
[3]
HepG2.C3A HYAL1
Mean 88.6
Standard deviation 33
Values 1.1e+02 65
[4]
HuH.7 HYAL1
Mean 1.54
Standard deviation 0.96
Values 0.95 2.7 1
[5]
SNU475 HYAL1
Mean 0.168
Standard deviation 0.058
Values 0.21 0.13
[6]
THLE HYAL1
Mean 0.868
Standard deviation 0.069
Values 0.92 0.82
[7]
liver HYAL1
Mean 66.7
Standard deviation 12
Values 80 54 73 59
[8]
ref_hepatocyte HEXB
Mean 33.9
Standard deviation 11
Values 39 33 16 44 38
[9]
HepG2 HEXB
Mean 64.1
Standard deviation 5.9
Values 68 60
[10]
HepG2.C3A HEXB
Mean 43.4
Standard deviation 2.1
Values 45 42
[11]
HuH.7 HEXB
Mean 61.5
Standard deviation 15
Values 46 77 61
[12]
SNU475 HEXB
Mean 37.4
Standard deviation 0.5
Values 37 38
[13]
THLE HEXB
Mean 71.3
Standard deviation 17
Values 59 83
[14]
liver HEXB
Mean 39
Standard deviation 15
Values 42 34 57 22
[15]
ref_hepatocyte GUSB
Mean 25.3
Standard deviation 23
Values 7 7.5 11 52 49
[16]
HepG2 GUSB
Mean 18.3
Standard deviation 3.5
Values 21 16
[17]
HepG2.C3A GUSB
Mean 20.1
Standard deviation 2
Values 22 19
[18]
HuH.7 GUSB
Mean 27.5
Standard deviation 3.9
Values 26 25 32
[19]
SNU475 GUSB
Mean 25.3
Standard deviation 2.9
Values 23 27
[20]
THLE GUSB
Mean 20
Standard deviation 0.097
Values 20 20
[21]
liver GUSB
Mean 42.1
Standard deviation 30
Values 54 22 79 14
[22]
ref_hepatocyte HEXA
Mean 15.3
Standard deviation 8.5
Values 11 11 6.1 25 24
[23]
HepG2 HEXA
Mean 91.6
Standard deviation 1.4
Values 93 91
[24]
HepG2.C3A HEXA
Mean 51.3
Standard deviation 2.1
Values 53 50
[25]
HuH.7 HEXA
Mean 39.8
Standard deviation 6.4
Values 37 35 47
[26]
SNU475 HEXA
Mean 51.2
Standard deviation 9
Values 58 45
[27]
THLE HEXA
Mean 54.1
Standard deviation 9.1
Values 48 61
[28]
liver HEXA
Mean 25.8
Standard deviation 15
Values 28 17 46 12
[29]
ref_hepatocyte CD44
Mean 12.9
Standard deviation 18
Values 0 19 41 1.6 2.3
[30]
HepG2 CD44
Mean 0.212
Standard deviation 0.15
Values 0.32 0.1
[31]
HepG2.C3A CD44
Mean 0.0667
Standard deviation 0.012
Values 0.058 0.075
[32]
HuH.7 CD44
Mean 5.5
Standard deviation 3
Values 7.8 2.2 6.5
[33]
SNU475 CD44
Mean 79.9
Standard deviation 47
Values 47 1.1e+02
[34]
THLE CD44
Mean 123
Standard deviation 24
Values 1.1e+02 1.4e+02
[35]
liver CD44
Mean 7.49
Standard deviation 3
Values 4 11 9 6.3
[36]
ref_hepatocyte HYAL2
Mean 5.55
Standard deviation 2.1
Values 4.6 3.2 6.6 8.7 4.7
[37]
HepG2 HYAL2
Mean 61.5
Standard deviation 5.1
Values 65 58
[38]
HepG2.C3A HYAL2
Mean 64
Standard deviation 2.5
Values 66 62
[39]
HuH.7 HYAL2
Mean 28.1
Standard deviation 10
Values 28 18 39
[40]
SNU475 HYAL2
Mean 8
Standard deviation 0.042
Values 8 8
[41]
THLE HYAL2
Mean 17.5
Standard deviation 3.3
Values 15 20
[42]
liver HYAL2
Mean 17.2
Standard deviation 2.7
Values 18 13 19 18
[43]
ref_hepatocyte HMMR
Mean 3.2
Standard deviation 4.7
Values 2.9 11 0.45 0.59 0.6
[44]
HepG2 HMMR
Mean 5.74
Standard deviation 2.6
Values 3.9 7.6
[45]
HepG2.C3A HMMR
Mean 42.7
Standard deviation 31
Values 21 65
[46]
HuH.7 HMMR
Mean 28.2
Standard deviation 7.4
Values 33 20 31
[47]
SNU475 HMMR
Mean 15.9
Standard deviation 2.1
Values 14 17
[48]
THLE HMMR
Mean 32.7
Standard deviation 2
Values 34 31
[49]
liver HMMR
Mean 1.45
Standard deviation 1.2
Values 0.75 2.2 2.7 0.093
[50]
ref_hepatocyte LYVE1
Mean 1.6
Standard deviation 2
Values 0 0 0.52 3.4 4
[51]
HepG2 LYVE1
Mean 3.08
Standard deviation 2.9
Values 1 5.1
[52]
HepG2.C3A LYVE1
Mean 0.924
Standard deviation 1
Values 0.18 1.7
[53]
HuH.7 LYVE1
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[54]
SNU475 LYVE1
Mean 0.208
Standard deviation 0.0062
Values 0.2 0.21
[55]
THLE LYVE1
Mean 0
Standard deviation 0
Values 0 0
[56]
liver LYVE1
Mean 28.3
Standard deviation 14
Values 15 46 31 21
[57]
ref_hepatocyte ABCC5
Mean 1.22
Standard deviation 0.91
Values 2.8 1.2 0.55 0.82 0.72
[58]
HepG2 ABCC5
Mean 15.8
Standard deviation 1.1
Values 17 15
[59]
HepG2.C3A ABCC5
Mean 14.6
Standard deviation 2.1
Values 16 13
[60]
HuH.7 ABCC5
Mean 11
Standard deviation 0.75
Values 12 11 10
[61]
SNU475 ABCC5
Mean 12.3
Standard deviation 2.6
Values 14 10
[62]
THLE ABCC5
Mean 14.1
Standard deviation 0.44
Values 14 14
[63]
liver ABCC5
Mean 7.03
Standard deviation 2.3
Values 4.6 10 6 7.5
[64]
ref_hepatocyte HYAL3
Mean 1.18
Standard deviation 1
Values 0.37 0.22 2.6 0.75 2
[65]
HepG2 HYAL3
Mean 10.2
Standard deviation 1.5
Values 9.2 11
[66]
HepG2.C3A HYAL3
Mean 4.74
Standard deviation 0.039
Values 4.8 4.7
[67]
HuH.7 HYAL3
Mean 5.68
Standard deviation 0.29
Values 5.4 5.7 6
[68]
SNU475 HYAL3
Mean 1.21
Standard deviation 0.21
Values 1.1 1.4
[69]
THLE HYAL3
Mean 2.51
Standard deviation 0.14
Values 2.4 2.6
[70]
liver HYAL3
Mean 0.856
Standard deviation 0.5
Values 1.4 0.26 1.1 0.65
[71]
ref_hepatocyte HAS3
Mean 0.939
Standard deviation 1.1
Values 0 1.5 2.6 0.37 0.22
[72]
HepG2 HAS3
Mean 0.948
Standard deviation 0.061
Values 0.99 0.91
[73]
HepG2.C3A HAS3
Mean 1.73
Standard deviation 0.13
Values 1.6 1.8
[74]
HuH.7 HAS3
Mean 0.473
Standard deviation 0.26
Values 0.26 0.76 0.39
[75]
SNU475 HAS3
Mean 2.81
Standard deviation 1.6
Values 1.7 3.9
[76]
THLE HAS3
Mean 0.535
Standard deviation 0.088
Values 0.6 0.47
[77]
liver HAS3
Mean 0.608
Standard deviation 0.62
Values 0.24 0.61 0.1 1.5
[78]
ref_hepatocyte SLC9A1
Mean 0.474
Standard deviation 0.24
Values 0.67 0.47 0.76 0.21 0.27
[79]
HepG2 SLC9A1
Mean 8.38
Standard deviation 0.027
Values 8.4 8.4
[80]
HepG2.C3A SLC9A1
Mean 3.51
Standard deviation 0.46
Values 3.8 3.2
[81]
HuH.7 SLC9A1
Mean 1.53
Standard deviation 0.077
Values 1.6 1.5 1.5
[82]
SNU475 SLC9A1
Mean 15.2
Standard deviation 0.69
Values 15 16
[83]
THLE SLC9A1
Mean 16
Standard deviation 1.1
Values 15 17
[84]
liver SLC9A1
Mean 1.12
Standard deviation 0.5
Values 1.9 0.71 0.98 0.94
[85]
ref_hepatocyte STAB2
Mean 0.234
Standard deviation 0.34
Values 0 0 0 0.44 0.73
[86]
HepG2 STAB2
Mean 0.0408
Standard deviation 0.0091
Values 0.034 0.047
[87]
HepG2.C3A STAB2
Mean 0.113
Standard deviation 0.037
Values 0.087 0.14
[88]
HuH.7 STAB2
Mean 0.0558
Standard deviation 0.029
Values 0.057 0.026 0.084
[89]
SNU475 STAB2
Mean 0.0903
Standard deviation 0.023
Values 0.074 0.11
[90]
THLE STAB2
Mean 0.0583
Standard deviation 0.06
Values 0.1 0.016
[91]
liver STAB2
Mean 44.2
Standard deviation 40
Values 9.1 1e+02 29 36
[92]
ref_hepatocyte HAS1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[93]
HepG2 HAS1
Mean 0.0294
Standard deviation 0.023
Values 0.046 0.013
[94]
HepG2.C3A HAS1
Mean 0.0253
Standard deviation 0.0055
Values 0.029 0.021
[95]
HuH.7 HAS1
Mean 0.0497
Standard deviation 0.0067
Values 0.057 0.045 0.047
[96]
SNU475 HAS1
Mean 0.125
Standard deviation 0.11
Values 0.046 0.2
[97]
THLE HAS1
Mean 67.7
Standard deviation 0.065
Values 68 68
[98]
liver HAS1
Mean 0.0242
Standard deviation 0.033
Values 0.071 0 0 0.026
[99]
ref_hepatocyte HAS2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[100]
HepG2 HAS2
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[101]
HepG2.C3A HAS2
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[102]
HuH.7 HAS2
Mean 0.187
Standard deviation 0.14
Values 0.15 0.35 0.066
[103]
SNU475 HAS2
Mean 0.525
Standard deviation 0.61
Values 0.093 0.96
[104]
THLE HAS2
Mean 5.24
Standard deviation 0.019
Values 5.2 5.3
[105]
liver HAS2
Mean 0.103
Standard deviation 0.054
Values 0.12 0.071 0.051 0.17
[106]
ref_hepatocyte CEMIP
Missing
[107]
HepG2 CEMIP
Missing
[108]
HepG2.C3A CEMIP
Missing
[109]
HuH.7 CEMIP
Missing
[110]
SNU475 CEMIP
Missing
[111]
THLE CEMIP
Missing
[112]
liver CEMIP
Missing
[113]
ref_hepatocyte CHP1
Missing
[114]
HepG2 CHP1
Mean 47
Standard deviation 9.2
Values 40 53
[115]
HepG2.C3A CHP1
Mean 46.4
Standard deviation 6.8
Values 51 42
[116]
HuH.7 CHP1
Mean 78.3
Standard deviation 10
Values 89 77 69
[117]
SNU475 CHP1
Mean 28.5
Standard deviation 3.6
Values 31 26
[118]
THLE CHP1
Mean 42.6
Standard deviation 7
Values 38 48
[119]
liver CHP1
Mean 155
Standard deviation 1e+02
Values 2.5e+02 63 2.3e+02 73