REACTOME_HS_GAG_BIOSYNTHESIS | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | GPC3 | Glypican-3 | [1] | 0.80[2] | 1.12[3] | 0.57[4] | -7.71[5] | -7.03[6] | -8.41[7] |
2 | SDC1 | Syndecan-1 | [8] | -1.87[9] | -2.44[10] | -1.28[11] | -2.16[12] | -3.99[13] | 0.60[14] |
3 | SDC4 | Syndecan-4 | [15] | -1.08[16] | -1.50[17] | -1.91[18] | -1.56[19] | 0.46[20] | -0.29[21] |
4 | SDC2 | Syndecan-2 | [22] | -0.97[23] | -0.13[24] | 0.32[25] | 0.01[26] | -2.73[27] | 0.45[28] |
5 | SLC35D2 | UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter | [29] | -2.60[30] | -1.74[31] | -0.58[32] | -2.18[33] | -2.59[34] | -2.32[35] |
6 | EXT1 | Exostosin-1 | [36] | -2.39[37] | -2.91[38] | -1.14[39] | 0.32[40] | 0.18[41] | -0.17[42] |
7 | HS6ST1 | Heparan-sulfate 6-O-sulfotransferase 1 | [43] | -0.03[44] | -0.23[45] | -1.39[46] | -0.59[47] | 0.36[48] | 0.07[49] |
8 | GPC1 | Glypican-1 | [50] | -0.88[51] | -4.32[52] | -7.52[53] | 2.65[54] | 1.90[55] | -0.71[56] |
9 | EXT2 | Exostosin-2 | [57] | 0.07[58] | -1.16[59] | -1.29[60] | -0.23[61] | 1.73[62] | 0.65[63] |
10 | AGRN | Agrin | [64] | 2.78[65] | 2.10[66] | 2.40[67] | 3.73[68] | 3.24[69] | 0.90[70] |
11 | HS2ST1 | Heparan sulfate 2-O-sulfotransferase 1 | [71] | 2.07[72] | 1.48[73] | 2.32[74] | 2.51[75] | 2.62[76] | 0.86[77] |
12 | NDST1 | Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 | [78] | 0.78[79] | 0.93[80] | 1.85[81] | 2.92[82] | 2.97[83] | 3.07[84] |
13 | HS3ST3B1 | Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 | [85] | -2.34[86] | -2.05[87] | -2.50[88] | -4.51[89] | -1.87[90] | 0.51[91] |
14 | GPC6 | Glypican-6 | [92] | 1.22[93] | 0.30[94] | 1.70[95] | 4.14[96] | 2.69[97] | 3.08[98] |
15 | GLCE | D-glucuronyl C5-epimerase | [99] | -0.46[100] | -0.06[101] | 1.33[102] | 0.63[103] | 2.20[104] | 2.03[105] |
16 | NDST2 | Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 | [106] | 0.28[107] | 0.94[108] | 0.54[109] | 1.52[110] | 2.41[111] | 1.50[112] |
17 | SDC3 | Syndecan-3 | [113] | 1.42[114] | -4.92[115] | -0.09[116] | 3.32[117] | 4.07[118] | 2.57[119] |
18 | HSPG2 | Basement membrane-specific heparan sulfate proteoglycan core protein | 6.23[120] | 4.37[121] | 5.58[122] | 6.24[123] | 6.87[124] | 6.19[125] | |
19 | GPC4 | Glypican-4 | [126] | -2.39[127] | -6.55[128] | -1.96[129] | 5.67[130] | -1.62[131] | 0.76[132] |
20 | HS3ST3A1 | Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 | [133] | -2.07[134] | -2.87[135] | 0.54[136] | 4.13[137] | 3.99[138] | 1.45[139] |
21 | HS6ST2 | Heparan-sulfate 6-O-sulfotransferase 2 | [140] | -1.82[141] | -2.15[142] | 5.93[143] | 0.89[144] | 0.40[145] | -2.17[146] |
22 | GPC5 | Glypican-5 | [147] | -4.57[148] | -5.99[149] | -0.79[150] | -3.05[151] | -2.06[152] | 3.39[153] |
23 | GPC2 | Glypican-2 | [154] | 1.52[155] | 0.86[156] | 3.70[157] | 3.53[158] | 2.85[159] | -3.25[160] |
24 | HS3ST1 | Heparan sulfate glucosamine 3-O-sulfotransferase 1 | [161] | [162] | [163] | -4.05[164] | -0.49[165] | -1.00[166] | 2.31[167] |
25 | NDST3 | Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 | [168] | -0.94[169] | 0.39[170] | 0.56[171] | 0.80[172] | 1.65[173] | 4.52[174] |
26 | HS3ST6 | Heparan sulfate glucosamine 3-O-sulfotransferase 6 | [175] | -3.21[176] | [177] | -3.31[178] | [179] | -2.60[180] | [181] |
27 | HS3ST2 | Heparan sulfate glucosamine 3-O-sulfotransferase 2 | [182] | [183] | [184] | [185] | -3.03[186] | -0.77[187] | -0.66[188] |
28 | HS6ST3 | Heparan-sulfate 6-O-sulfotransferase 3 | [189] | 1.81[190] | -0.74[191] | -0.84[192] | 5.24[193] | 8.88[194] | 0.34[195] |
29 | HS3ST4 | Heparan sulfate glucosamine 3-O-sulfotransferase 4 | [196] | [197] | [198] | [199] | [200] | [201] | [202] |
30 | HS3ST5 | Heparan sulfate glucosamine 3-O-sulfotransferase 5 | [203] | [204] | [205] | [206] | [207] | [208] | [209] |
31 | NDST4 | Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 | [210] | [211] | [212] | [213] | [214] | [215] | [216] |