REACTOME_HOMOLOGOUS_DNA_PAIRING_AND_STRAND_EXCHANGE | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | RPA2 | Replication protein A 32 kDa subunit | [1] | -1.84[2] | -2.44[3] | -2.08[4] | -1.66[5] | -1.77[6] | -2.70[7] |
2 | RFC4 | Replication factor C subunit 4 | [8] | -1.36[9] | -1.40[10] | -1.01[11] | -1.89[12] | -0.74[13] | -3.06[14] |
3 | RAD51C | DNA repair protein RAD51 homolog 3 | [15] | -0.80[16] | -1.24[17] | -1.60[18] | -3.10[19] | -1.75[20] | -2.56[21] |
4 | RFC2 | Replication factor C subunit 2 | [22] | -0.65[23] | -1.47[24] | -1.62[25] | -0.74[26] | -0.47[27] | -1.08[28] |
5 | RPA1 | Replication protein A 70 kDa DNA-binding subunit | [29] | 0.93[30] | -0.01[31] | 0.07[32] | 0.93[33] | 0.76[34] | -0.30[35] |
6 | RPA3 | Replication protein A 14 kDa subunit | [36] | -0.75[37] | -0.63[38] | -0.10[39] | -1.83[40] | -1.73[41] | -1.00[42] |
7 | RAD17 | Cell cycle checkpoint protein RAD17 | [43] | -1.23[44] | -0.82[45] | -0.96[46] | -1.26[47] | -1.10[48] | -0.74[49] |
8 | KAT5 | Histone acetyltransferase KAT5 | [50] | -1.16[51] | -1.43[52] | -2.65[53] | -1.76[54] | -2.03[55] | -1.37[56] |
9 | NBN | Nibrin | [57] | -0.80[58] | -0.30[59] | -0.74[60] | 0.58[61] | -0.48[62] | 0.97[63] |
10 | RFC5 | Replication factor C subunit 5 | [64] | -0.26[65] | -0.47[66] | -0.47[67] | -0.66[68] | -0.31[69] | -1.18[70] |
11 | RAD51 | DNA repair protein RAD51 homolog 1 | [71] | -0.64[72] | -1.50[73] | -1.59[74] | -1.10[75] | -1.32[76] | -4.25[77] |
12 | RAD50 | DNA repair protein RAD50 | [78] | -0.23[79] | 1.22[80] | 0.18[81] | 0.35[82] | 0.65[83] | 1.90[84] |
13 | RMI2 | RecQ-mediated genome instability protein 2 | [85] | 0.86[86] | -0.53[87] | -0.76[88] | -2.12[89] | -2.00[90] | -4.74[91] |
14 | RBBP8 | DNA endonuclease RBBP8 | [92] | -0.19[93] | 0.55[94] | -1.02[95] | 0.51[96] | 0.53[97] | -0.06[98] |
15 | TOPBP1 | DNA topoisomerase 2-binding protein 1 | [99] | 0.64[100] | 1.00[101] | 0.96[102] | 1.21[103] | 1.43[104] | 0.58[105] |
16 | RFC3 | Replication factor C subunit 3 | [106] | 0.79[107] | 0.98[108] | 0.93[109] | 0.33[110] | 0.74[111] | -1.17[112] |
17 | HUS1 | Checkpoint protein HUS1 | [113] | -1.10[114] | -1.50[115] | -1.15[116] | -1.03[117] | -1.41[118] | 1.07[119] |
18 | CHEK1 | Serine/threonine-protein kinase Chk1 | [120] | 1.15[121] | 0.84[122] | 0.21[123] | 1.23[124] | 1.27[125] | -2.33[126] |
19 | TOP3A | DNA topoisomerase 3-alpha | [127] | 1.58[128] | 0.58[129] | 0.69[130] | 0.93[131] | 1.13[132] | 1.49[133] |
20 | RAD1 | Cell cycle checkpoint protein RAD1 | [134] | 0.98[135] | 0.99[136] | 1.33[137] | 0.88[138] | 1.59[139] | 0.60[140] |
21 | PALB2 | Partner and localizer of BRCA2 | [141] | 1.38[142] | 1.01[143] | 0.44[144] | -0.22[145] | 0.08[146] | 0.37[147] |
22 | RAD9A | Cell cycle checkpoint control protein RAD9A | [148] | -0.32[149] | -0.71[150] | 0.91[151] | 1.41[152] | -0.95[153] | -0.48[154] |
23 | BRCA1 | Breast cancer type 1 susceptibility protein | [155] | 1.28[156] | 1.86[157] | 2.06[158] | 1.22[159] | 1.56[160] | 1.37[161] |
24 | ATRIP | ATR-interacting protein | [162] | -0.14[163] | -0.57[164] | 0.11[165] | -1.27[166] | -0.37[167] | -0.47[168] |
25 | ATR | Serine/threonine-protein kinase ATR | [169] | 0.71[170] | 1.03[171] | 0.92[172] | 1.61[173] | 1.38[174] | 3.24[175] |
26 | WRN | Werner syndrome ATP-dependent helicase | [176] | 0.22[177] | 1.01[178] | 2.76[179] | 0.78[180] | 0.41[181] | 1.66[182] |
27 | RAD51D | DNA repair protein RAD51 homolog 4 | [183] | 0.34[184] | -0.32[185] | 0.22[186] | 0.13[187] | -0.62[188] | -0.55[189] |
28 | RAD51AP1 | RAD51-associated protein 1 | [190] | 1.11[191] | 1.90[192] | 2.40[193] | 1.14[194] | 1.77[195] | -1.82[196] |
29 | RMI1 | RecQ-mediated genome instability protein 1 | [197] | 0.20[198] | 0.76[199] | 1.02[200] | 1.16[201] | 1.82[202] | 0.68[203] |
30 | XRCC2 | DNA repair protein XRCC2 | [204] | -0.21[205] | -0.09[206] | 0.07[207] | -0.12[208] | -0.06[209] | -2.57[210] |
31 | ATM | Serine-protein kinase ATM | [211] | 2.64[212] | 3.57[213] | 3.11[214] | 3.24[215] | 2.53[216] | 4.68[217] |
32 | RAD51B | DNA repair protein RAD51 homolog 2 | [218] | -0.53[219] | -1.09[220] | -1.26[221] | -0.85[222] | -1.23[223] | -0.85[224] |
33 | DNA2 | DNA replication ATP-dependent helicase/nuclease DNA2 | [225] | 1.37[226] | 2.47[227] | 1.48[228] | 1.73[229] | 1.20[230] | 1.26[231] |
34 | EXO1 | Exonuclease 1 | [232] | 1.52[233] | 1.13[234] | 2.11[235] | 2.86[236] | 1.95[237] | -1.78[238] |
35 | XRCC3 | DNA repair protein XRCC3 | [239] | 2.66[240] | 2.16[241] | 1.67[242] | 2.26[243] | 2.53[244] | 1.41[245] |
36 | BRIP1 | Fanconi anemia group J protein | [246] | 1.76[247] | 2.49[248] | 2.30[249] | 2.29[250] | 2.14[251] | 1.65[252] |
37 | BLM | Bloom syndrome protein | [253] | 1.16[254] | 1.84[255] | 2.45[256] | 1.97[257] | 1.87[258] | -0.69[259] |
38 | BARD1 | BRCA1-associated RING domain protein 1 | [260] | 0.93[261] | 1.24[262] | 1.07[263] | 1.78[264] | 1.67[265] | 1.56[266] |
39 | RAD9B | Cell cycle checkpoint control protein RAD9B | [267] | -3.72[268] | -1.19[269] | -2.07[270] | -0.49[271] | -1.34[272] | -1.09[273] |
40 | BRCA2 | Breast cancer type 2 susceptibility protein | [274] | 2.41[275] | 4.23[276] | 4.21[277] | 3.55[278] | 3.52[279] | 3.13[280] |
41 | MRE11 | Double-strand break repair protein MRE11 | [281] | [282] | [283] | [284] | [285] | [286] | [287] |
42 | RHNO1 | RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 | [288] | [289] | [290] | [291] | [292] | [293] | [294] |