REACTOME_HEME_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 APOA1 Apolipoprotein A-I [1] -2.05[2] -1.56[3] -3.38[4] -10.27[5] -10.42[6] -1.57[7]
2 APOB Apolipoprotein B-100 [8] 4.13[9] 4.11[10] 4.10[11] -3.65[12] -3.58[13] 4.44[14]
3 HMOX1 Heme oxygenase 1 [15] 1.70[16] -0.01[17] -0.31[18] 2.19[19] 1.96[20] -2.51[21]
4 HBB Hemoglobin subunit beta [22] [23] [24] [25] [26] [27] -2.07[28]
5 NFE2L2 Nuclear factor erythroid 2-related factor 2 [29] 2.95[30] 3.10[31] 3.51[32] 4.25[33] 4.50[34] -0.25[35]
6 RXRA Retinoic acid receptor RXR-alpha [36] 2.13[37] 1.14[38] 2.80[39] 3.80[40] 3.48[41] 1.73[42]
7 XPO1 Exportin-1 [43] 3.55[44] 3.47[45] 4.31[46] 5.92[47] 6.02[48] 0.44[49]
8 HDAC3 Histone deacetylase 3 [50] 2.67[51] 1.93[52] 2.55[53] 3.74[54] 3.91[55] -0.82[56]
9 HBA1 Hemoglobin subunit alpha [57] -5.76[58] -9.29[59] -9.04[60] [61] -6.53[62] -4.02[63]
10 CARM1 Histone-arginine methyltransferase CARM1 [64] 3.64[65] 2.30[66] 3.44[67] 3.54[68] 4.34[69] -1.44[70]
11 ATF2 Cyclic AMP-dependent transcription factor ATF-2 [71] 2.82[72] 3.09[73] 4.13[74] 4.57[75] 4.35[76] 0.60[77]
12 CRTC2 CREB-regulated transcription coactivator 2 [78] 1.55[79] 0.91[80] 2.78[81] 4.26[82] 4.27[83] -1.49[84]
13 NCOR1 Nuclear receptor corepressor 1 [85] 3.27[86] 2.98[87] 4.44[88] 5.36[89] 5.41[90] 2.38[91]
14 MAFK Transcription factor MafK [92] 2.55[93] 1.19[94] 1.50[95] 2.21[96] 3.18[97] -2.57[98]
15 NR1D1 Nuclear receptor subfamily 1 group D member 1 [99] 0.91[100] -0.20[101] 1.12[102] 2.67[103] 2.08[104] -1.38[105]
16 HBA2 [106] [107] [108] [109] -8.53[110] [111] -2.41[112]
17 ARNTL Aryl hydrocarbon receptor nuclear translocator-like protein 1 [113] 0.11[114] -0.17[115] -0.32[116] 2.74[117] 2.94[118] 0.37[119]
18 TBL1XR1 F-box-like/WD repeat-containing protein TBL1XR1 [120] 3.27[121] 3.02[122] 4.47[123] 6.20[124] 5.77[125] 2.45[126]
19 TBL1X F-box-like/WD repeat-containing protein TBL1X [127] 3.53[128] 3.14[129] 5.51[130] -0.61[131] 4.89[132] 1.32[133]
20 SLC46A1 Proton-coupled folate transporter [134] 2.10[135] 1.70[136] 2.25[137] 2.46[138] 2.06[139] 0.79[140]
21 PPARA Peroxisome proliferator-activated receptor alpha [141] 2.86[142] 3.05[143] 4.72[144] 3.82[145] 3.00[146] 3.73[147]
22 MED1 Mediator of RNA polymerase II transcription subunit 1 [148] 4.73[149] 3.27[150] 4.98[151] 5.98[152] 6.15[153] 0.86[154]
23 NPAS2 Neuronal PAS domain-containing protein 2 [155] 3.77[156] 3.65[157] 4.05[158] 1.41[159] 3.64[160] -0.61[161]
24 BACH1 Transcription regulator protein BACH1 [162] 3.23[163] 2.77[164] 4.03[165] 5.91[166] 5.15[167] 2.21[168]
25 NRIP1 Nuclear receptor-interacting protein 1 [169] 3.80[170] 4.30[171] 3.86[172] 6.72[173] 5.92[174] 2.19[175]
26 LY96 Lymphocyte antigen 96 [176] -0.47[177] -1.64[178] -7.25[179] 2.42[180] -1.18[181] -1.78[182]
27 NCOA6 Nuclear receptor coactivator 6 [183] 4.39[184] 3.45[185] 4.47[186] 6.35[187] 5.61[188] 0.99[189]
28 EP300 Histone acetyltransferase p300 [190] 4.91[191] 3.71[192] 5.42[193] 6.36[194] 6.42[195] 2.33[196]
29 MEF2D Myocyte-specific enhancer factor 2D [197] 2.93[198] 2.00[199] 3.53[200] 6.37[201] 5.96[202] 0.43[203]
30 TGS1 Trimethylguanosine synthase [204] 2.78[205] 2.43[206] 3.78[207] 5.50[208] 5.34[209] 0.56[210]
31 NCOA1 Nuclear receptor coactivator 1 [211] 2.65[212] 2.43[213] 3.44[214] 5.58[215] 5.04[216] 2.23[217]
32 PPARGC1A Peroxisome proliferator-activated receptor gamma coactivator 1-alpha 1.10[218] 3.20[219] -6.77[220] 4.55[221] 1.26[222] 3.01[223]
33 SIRT1 NAD-dependent protein deacetylase sirtuin-1 [224] 2.69[225] 3.00[226] 3.36[227] 5.35[228] 5.61[229] 0.92[230]
34 CREB1 Cyclic AMP-responsive element-binding protein 1 [231] 3.91[232] 4.28[233] 5.58[234] 6.33[235] 6.28[236] 1.92[237]
35 CREBBP CREB-binding protein [238] 5.09[239] 3.51[240] 4.93[241] 6.54[242] 6.56[243] 2.81[244]
36 CLOCK Circadian locomoter output cycles protein kaput [245] 2.97[246] 3.39[247] 3.95[248] 6.13[249] 6.76[250] 3.00[251]
37 CRTC3 CREB-regulated transcription coactivator 3 [252] 3.57[253] 2.41[254] 3.62[255] 5.88[256] 5.80[257] 0.87[258]
38 RORA Nuclear receptor ROR-alpha [259] 2.47[260] 3.87[261] 2.89[262] 0.59[263] 1.99[264] 3.92[265]
39 CHD9 Chromodomain-helicase-DNA-binding protein 9 [266] 3.51[267] 4.82[268] 4.87[269] 6.17[270] 7.19[271] 4.51[272]
40 NCOA2 Nuclear receptor coactivator 2 [273] 3.76[274] 3.79[275] 6.43[276] 6.99[277] 5.29[278] 4.18[279]
41 USP46 Ubiquitin carboxyl-terminal hydrolase 46 [280] 4.41[281] 3.45[282] 5.77[283] 5.98[284] 6.49[285] 1.70[286]
42 CLEC1B C-type lectin domain family 1 member B [287] [288] [289] [290] -3.92[291] [292] 2.68[293]
43 RAI1 Retinoic acid-induced protein 1 [294] 6.16[295] 4.73[296] 5.74[297] 8.31[298] 7.82[299] 1.76[300]
44 TLR4 Toll-like receptor 4 [301] 2.46[302] -3.48[303] -3.56[304] -1.31[305] 9.12[306] 4.04[307]
45 CRTC1 CREB-regulated transcription coactivator 1 [308] 4.88[309] 4.60[310] 6.48[311] 6.18[312] 5.96[313] 1.53[314]
46 SMARCD3 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 3.66[315] 1.20[316] 4.06[317] 7.05[318] 7.25[319] 0.94[320]
47 MEF2C Myocyte-specific enhancer factor 2C [321] -0.92[322] -0.58[323] 5.19[324] 9.40[325] 5.39[326] 4.87[327]
48 HELZ2 Helicase with zinc finger domain 2 [328] [329] [330] [331] [332] [333] [334]
[1]
ref_hepatocyte APOA1
Mean 5.54e+03
Standard deviation 5.9e+03
Values 4.7e+03 1.6e+02 9e+02 7.3e+03 1.5e+04
[2]
HepG2 APOA1
Mean 647
Standard deviation 1.1e+02
Values 5.7e+02 7.2e+02
[3]
HepG2.C3A APOA1
Mean 1.4e+03
Standard deviation 4.2e+02
Values 1.7e+03 1.1e+03
[4]
HuH.7 APOA1
Mean 217
Standard deviation 31
Values 1.8e+02 2.4e+02 2.3e+02
[5]
SNU475 APOA1
Mean 0.596
Standard deviation 0.16
Values 0.48 0.71
[6]
THLE APOA1
Mean 0.598
Standard deviation 0.26
Values 0.78 0.41
[7]
liver APOA1
Mean 3.55e+03
Standard deviation 3.2e+03
Values 6.9e+03 8.6e+02 5.7e+03 7.4e+02
[8]
ref_hepatocyte APOB
Mean 165
Standard deviation 1.5e+02
Values 2.4e+02 15 8.3 2.2e+02 3.4e+02
[9]
HepG2 APOB
Mean 1.41e+03
Standard deviation 6.5e+02
Values 9.5e+02 1.9e+03
[10]
HepG2.C3A APOB
Mean 2.13e+03
Standard deviation 5.8e+02
Values 1.7e+03 2.5e+03
[11]
HuH.7 APOB
Mean 1.16e+03
Standard deviation 4.8e+02
Values 1.4e+03 1.5e+03 6.1e+02
[12]
SNU475 APOB
Mean 1.75
Standard deviation 0.12
Values 1.7 1.8
[13]
THLE APOB
Mean 2.04
Standard deviation 0.96
Values 2.7 1.4
[14]
liver APOB
Mean 6.85e+03
Standard deviation 4.5e+03
Values 2.9e+03 1.2e+04 3.6e+03 8.5e+03
[15]
ref_hepatocyte HMOX1
Mean 45.4
Standard deviation 44
Values 19 4.5 1.2e+02 47 37
[16]
HepG2 HMOX1
Mean 71.8
Standard deviation 29
Values 92 52
[17]
HepG2.C3A HMOX1
Mean 33.6
Standard deviation 4.7
Values 30 37
[18]
HuH.7 HMOX1
Mean 14.9
Standard deviation 6.3
Values 10 22 12
[19]
SNU475 HMOX1
Mean 27.6
Standard deviation 4.6
Values 24 31
[20]
THLE HMOX1
Mean 26.2
Standard deviation 9.7
Values 19 33
[21]
liver HMOX1
Mean 15.2
Standard deviation 2.1
Values 16 13 18 15
[22]
ref_hepatocyte HBB
Mean 27.3
Standard deviation 31
Values 0 0 16 59 61
[23]
HepG2 HBB
Mean 0
Standard deviation 0
Values 0 0
[24]
HepG2.C3A HBB
Mean 0
Standard deviation 0
Values 0 0
[25]
HuH.7 HBB
Mean 0
Standard deviation 0
Values 0 0 0
[26]
SNU475 HBB
Mean 0
Standard deviation 0
Values 0 0
[27]
THLE HBB
Mean 0
Standard deviation 0
Values 0 0
[28]
liver HBB
Mean 12.4
Standard deviation 20
Values 3 4 42 0.4
[29]
ref_hepatocyte NFE2L2
Mean 15.6
Standard deviation 4.9
Values 18 9.4 11 21 19
[30]
HepG2 NFE2L2
Mean 58.6
Standard deviation 25
Values 41 76
[31]
HepG2.C3A NFE2L2
Mean 99.8
Standard deviation 19
Values 86 1.1e+02
[32]
HuH.7 NFE2L2
Mean 72.7
Standard deviation 3
Values 69 75 74
[33]
SNU475 NFE2L2
Mean 39.6
Standard deviation 2.1
Values 38 41
[34]
THLE NFE2L2
Mean 52.3
Standard deviation 3.2
Values 55 50
[35]
liver NFE2L2
Mean 25
Standard deviation 9.2
Values 28 21 36 15
[36]
ref_hepatocyte RXRA
Mean 14.5
Standard deviation 6.1
Values 15 7.5 9.4 22 18
[37]
HepG2 RXRA
Mean 30.9
Standard deviation 2.8
Values 33 29
[38]
HepG2.C3A RXRA
Mean 23.9
Standard deviation 6.1
Values 28 20
[39]
HuH.7 RXRA
Mean 41.2
Standard deviation 10
Values 42 51 30
[40]
SNU475 RXRA
Mean 26.9
Standard deviation 8.3
Values 33 21
[41]
THLE RXRA
Mean 23.9
Standard deviation 7.5
Values 19 29
[42]
liver RXRA
Mean 91.4
Standard deviation 37
Values 1.3e+02 72 49 1.2e+02
[43]
ref_hepatocyte XPO1
Mean 13.2
Standard deviation 5.7
Values 20 19 8.6 8.1 11
[44]
HepG2 XPO1
Mean 74.7
Standard deviation 37
Values 48 1e+02
[45]
HepG2.C3A XPO1
Mean 109
Standard deviation 54
Values 71 1.5e+02
[46]
HuH.7 XPO1
Mean 107
Standard deviation 26
Values 1.3e+02 77 1.2e+02
[47]
SNU475 XPO1
Mean 106
Standard deviation 0.46
Values 1.1e+02 1.1e+02
[48]
THLE XPO1
Mean 127
Standard deviation 5.2
Values 1.2e+02 1.3e+02
[49]
liver XPO1
Mean 34
Standard deviation 14
Values 22 53 24 37
[50]
ref_hepatocyte HDAC3
Mean 12.4
Standard deviation 2.7
Values 17 10 11 14 10
[51]
HepG2 HDAC3
Mean 38.3
Standard deviation 1.2
Values 37 39
[52]
HepG2.C3A HDAC3
Mean 35.4
Standard deviation 3.2
Values 33 38
[53]
HuH.7 HDAC3
Mean 29.6
Standard deviation 5.9
Values 28 24 36
[54]
SNU475 HDAC3
Mean 22
Standard deviation 2.2
Values 24 20
[55]
THLE HDAC3
Mean 27.5
Standard deviation 0.73
Values 27 28
[56]
liver HDAC3
Mean 13.3
Standard deviation 5.1
Values 19 8.2 16 10
[57]
ref_hepatocyte HBA1
Mean 9.02
Standard deviation 9.5
Values 0 0 7.4 20 18
[58]
HepG2 HBA1
Mean 0.0809
Standard deviation 0.023
Values 0.097 0.064
[59]
HepG2.C3A HBA1
Mean 0.0107
Standard deviation 0.015
Values 0 0.021
[60]
HuH.7 HBA1
Mean 0.00701
Standard deviation 0.0065
Values 0.0082 0.013 0
[61]
SNU475 HBA1
Mean 0
Standard deviation 0
Values 0 0
[62]
THLE HBA1
Mean 0.0145
Standard deviation 0.013
Values 0.024 0.0053
[63]
liver HBA1
Mean 1.06
Standard deviation 1.7
Values 0.63 0.014 3.5 0.04
[64]
ref_hepatocyte CARM1
Mean 8
Standard deviation 2.2
Values 5.9 8.2 11 8.8 5.9
[65]
HepG2 CARM1
Mean 48.4
Standard deviation 14
Values 58 38
[66]
HepG2.C3A CARM1
Mean 29.4
Standard deviation 7.1
Values 34 24
[67]
HuH.7 CARM1
Mean 35.4
Standard deviation 7.6
Values 42 27 38
[68]
SNU475 CARM1
Mean 12.4
Standard deviation 1.6
Values 13 11
[69]
THLE CARM1
Mean 24
Standard deviation 2.8
Values 22 26
[70]
liver CARM1
Mean 5.61
Standard deviation 1.3
Values 5.9 5.1 4.1 7.3
[71]
ref_hepatocyte ATF2
Mean 7.65
Standard deviation 3.4
Values 12 6.7 9.4 3.3 6.6
[72]
HepG2 ATF2
Mean 26.3
Standard deviation 12
Values 18 35
[73]
HepG2.C3A ATF2
Mean 48.4
Standard deviation 7.6
Values 43 54
[74]
HuH.7 ATF2
Mean 54.5
Standard deviation 4.5
Values 55 59 50
[75]
SNU475 ATF2
Mean 24.2
Standard deviation 8.8
Values 30 18
[76]
THLE ATF2
Mean 23.1
Standard deviation 0.6
Values 24 23
[77]
liver ATF2
Mean 22
Standard deviation 3.2
Values 19 26 23 20
[78]
ref_hepatocyte CRTC2
Mean 7.28
Standard deviation 7.9
Values 1.4 0.96 20 8.5 5.1
[79]
HepG2 CRTC2
Mean 10.3
Standard deviation 1.4
Values 11 9.4
[80]
HepG2.C3A CRTC2
Mean 10.2
Standard deviation 3.4
Values 13 7.8
[81]
HuH.7 CRTC2
Mean 20.4
Standard deviation 3
Values 18 24 19
[82]
SNU475 CRTC2
Mean 18.6
Standard deviation 1.8
Values 17 20
[83]
THLE CRTC2
Mean 20.7
Standard deviation 1.4
Values 20 22
[84]
liver CRTC2
Mean 4.93
Standard deviation 3.5
Values 9.4 1.7 6.1 2.6
[85]
ref_hepatocyte NCOR1
Mean 7.02
Standard deviation 2.9
Values 10 10 5.5 4.3 5.1
[86]
HepG2 NCOR1
Mean 32.8
Standard deviation 11
Values 25 41
[87]
HepG2.C3A NCOR1
Mean 41.3
Standard deviation 1.3
Values 40 42
[88]
HuH.7 NCOR1
Mean 62.2
Standard deviation 16
Values 78 63 46
[89]
SNU475 NCOR1
Mean 38.2
Standard deviation 4.6
Values 42 35
[90]
THLE NCOR1
Mean 44.2
Standard deviation 1.4
Values 43 45
[91]
liver NCOR1
Mean 69.4
Standard deviation 14
Values 87 68 52 70
[92]
ref_hepatocyte MAFK
Mean 6.99
Standard deviation 6
Values 6.1 7.7 17 3.6 0.9
[93]
HepG2 MAFK
Mean 19.8
Standard deviation 11
Values 28 12
[94]
HepG2.C3A MAFK
Mean 11.9
Standard deviation 6.7
Values 17 7.1
[95]
HuH.7 MAFK
Mean 8.06
Standard deviation 2.2
Values 7.1 11 6.6
[96]
SNU475 MAFK
Mean 4.3
Standard deviation 0.066
Values 4.3 4.3
[97]
THLE MAFK
Mean 9.37
Standard deviation 1.2
Values 8.5 10
[98]
liver MAFK
Mean 2.24
Standard deviation 2.1
Values 0.56 3.8 0.28 4.3
[99]
ref_hepatocyte NR1D1
Mean 6.83
Standard deviation 12
Values 0.3 0.38 28 3.3 1.9
[100]
HepG2 NR1D1
Mean 6.24
Standard deviation 3.5
Values 8.7 3.7
[101]
HepG2.C3A NR1D1
Mean 4.42
Standard deviation 2.4
Values 6.1 2.7
[102]
HuH.7 NR1D1
Mean 6.06
Standard deviation 2.4
Values 5.6 8.7 4
[103]
SNU475 NR1D1
Mean 5.79
Standard deviation 1.3
Values 4.9 6.7
[104]
THLE NR1D1
Mean 4.28
Standard deviation 0.22
Values 4.1 4.4
[105]
liver NR1D1
Mean 4.99
Standard deviation 4
Values 9.9 2.1 6.7 1.3
[106]
ref_hepatocyte HBA2
Mean 6.42
Standard deviation 10
Values 0 0 1 7.1 24
[107]
HepG2 HBA2
Mean 0
Standard deviation 0
Values 0 0
[108]
HepG2.C3A HBA2
Mean 0
Standard deviation 0
Values 0 0
[109]
HuH.7 HBA2
Mean 0
Standard deviation 0
Values 0 0 0
[110]
SNU475 HBA2
Mean 0.00232
Standard deviation 0.0033
Values 0.0046 0
[111]
THLE HBA2
Mean 0
Standard deviation 0
Values 0 0
[112]
liver HBA2
Mean 2.3
Standard deviation 4.1
Values 0.61 0.2 8.4 0.013
[113]
ref_hepatocyte ARNTL
Mean 5.32
Standard deviation 2.6
Values 1.3 5.3 4.6 7.9 7.5
[114]
HepG2 ARNTL
Mean 2.79
Standard deviation 0.22
Values 2.6 2.9
[115]
HepG2.C3A ARNTL
Mean 3.53
Standard deviation 0.11
Values 3.6 3.5
[116]
HuH.7 ARNTL
Mean 1.74
Standard deviation 0.12
Values 1.6 1.8 1.8
[117]
SNU475 ARNTL
Mean 4.73
Standard deviation 0.49
Values 4.4 5.1
[118]
THLE ARNTL
Mean 6.03
Standard deviation 0.14
Values 5.9 6.1
[119]
liver ARNTL
Mean 13.1
Standard deviation 2.3
Values 12 12 17 12
[120]
ref_hepatocyte TBL1XR1
Mean 4.61
Standard deviation 1.6
Values 4.2 6.5 3.3 3.1 6
[121]
HepG2 TBL1XR1
Mean 21.5
Standard deviation 5.1
Values 18 25
[122]
HepG2.C3A TBL1XR1
Mean 27.8
Standard deviation 0.088
Values 28 28
[123]
HuH.7 TBL1XR1
Mean 41.7
Standard deviation 12
Values 37 55 33
[124]
SNU475 TBL1XR1
Mean 45
Standard deviation 0.79
Values 46 44
[125]
THLE TBL1XR1
Mean 37.2
Standard deviation 0.85
Values 38 37
[126]
liver TBL1XR1
Mean 47.9
Standard deviation 6.3
Values 46 56 41 48
[127]
ref_hepatocyte TBL1X
Mean 4.34
Standard deviation 1.4
Values 6.3 5.1 2.8 3.5 4
[128]
HepG2 TBL1X
Mean 24.3
Standard deviation 2.7
Values 22 26
[129]
HepG2.C3A TBL1X
Mean 28.6
Standard deviation 4.5
Values 32 25
[130]
HuH.7 TBL1X
Mean 80.9
Standard deviation 15
Values 88 92 63
[131]
SNU475 TBL1X
Mean 0.377
Standard deviation 0.13
Values 0.28 0.47
[132]
THLE TBL1X
Mean 19
Standard deviation 0.42
Values 19 19
[133]
liver TBL1X
Mean 20.7
Standard deviation 8.5
Values 33 18 19 13
[134]
ref_hepatocyte SLC46A1
Mean 4.01
Standard deviation 2.2
Values 5.3 1.5 1.7 6.2 5.3
[135]
HepG2 SLC46A1
Mean 8.35
Standard deviation 1.4
Values 7.4 9.4
[136]
HepG2.C3A SLC46A1
Mean 9.72
Standard deviation 1.6
Values 11 8.6
[137]
HuH.7 SLC46A1
Mean 7.78
Standard deviation 1.9
Values 7.2 9.9 6.3
[138]
SNU475 SLC46A1
Mean 2.94
Standard deviation 0.048
Values 2.9 3
[139]
THLE SLC46A1
Mean 2.47
Standard deviation 0.27
Values 2.3 2.7
[140]
liver SLC46A1
Mean 13.2
Standard deviation 3.5
Values 16 9.6 11 16
[141]
ref_hepatocyte PPARA
Mean 3.95
Standard deviation 2.1
Values 4.6 1.9 1.6 5.5 6.2
[142]
HepG2 PPARA
Mean 13.9
Standard deviation 0.43
Values 14 14
[143]
HepG2.C3A PPARA
Mean 24.4
Standard deviation 5.6
Values 28 20
[144]
HuH.7 PPARA
Mean 42.3
Standard deviation 18
Values 42 60 25
[145]
SNU475 PPARA
Mean 7.44
Standard deviation 1.6
Values 8.5 6.3
[146]
THLE PPARA
Mean 4.68
Standard deviation 0.38
Values 4.9 4.4
[147]
liver PPARA
Mean 99.6
Standard deviation 24
Values 88 1.3e+02 97 79
[148]
ref_hepatocyte MED1
Mean 3.71
Standard deviation 3.1
Values 8.9 3.7 3.2 1.1 1.6
[149]
HepG2 MED1
Mean 47.9
Standard deviation 11
Values 40 56
[150]
HepG2.C3A MED1
Mean 26.7
Standard deviation 5
Values 23 30
[151]
HuH.7 MED1
Mean 47.9
Standard deviation 9.7
Values 59 46 40
[152]
SNU475 MED1
Mean 31.3
Standard deviation 2.2
Values 30 33
[153]
THLE MED1
Mean 39.1
Standard deviation 2.7
Values 37 41
[154]
liver MED1
Mean 12.8
Standard deviation 1.3
Values 13 14 11 13
[155]
ref_hepatocyte NPAS2
Mean 3.6
Standard deviation 1.4
Values 3.9 2 3.5 5.7 2.9
[156]
HepG2 NPAS2
Mean 23.8
Standard deviation 0.38
Values 24 24
[157]
HepG2.C3A NPAS2
Mean 33.8
Standard deviation 11
Values 42 26
[158]
HuH.7 NPAS2
Mean 24.3
Standard deviation 6.4
Values 30 17 26
[159]
SNU475 NPAS2
Mean 1.27
Standard deviation 1.1
Values 0.47 2.1
[160]
THLE NPAS2
Mean 6.67
Standard deviation 0.73
Values 7.2 6.1
[161]
liver NPAS2
Mean 4.49
Standard deviation 1.6
Values 5 3.8 6.4 2.7
[162]
ref_hepatocyte BACH1
Mean 3.37
Standard deviation 1.7
Values 4 6 2.2 2.2 2.4
[163]
HepG2 BACH1
Mean 15.4
Standard deviation 2
Values 14 17
[164]
HepG2.C3A BACH1
Mean 17.2
Standard deviation 0.92
Values 17 18
[165]
HuH.7 BACH1
Mean 22.6
Standard deviation 5.9
Values 24 27 16
[166]
SNU475 BACH1
Mean 26.9
Standard deviation 2.6
Values 29 25
[167]
THLE BACH1
Mean 17.7
Standard deviation 0.89
Values 18 17
[168]
liver BACH1
Mean 29.7
Standard deviation 14
Values 16 48 22 32
[169]
ref_hepatocyte NRIP1
Mean 3.23
Standard deviation 1.9
Values 6.5 2.9 3 1.5 2.2
[170]
HepG2 NRIP1
Mean 21.8
Standard deviation 7
Values 17 27
[171]
HepG2.C3A NRIP1
Mean 47.3
Standard deviation 8.4
Values 41 53
[172]
HuH.7 NRIP1
Mean 19.2
Standard deviation 8.7
Values 17 29 12
[173]
SNU475 NRIP1
Mean 45.2
Standard deviation 4.6
Values 42 48
[174]
THLE NRIP1
Mean 29
Standard deviation 7.8
Values 35 23
[175]
liver NRIP1
Mean 28
Standard deviation 18
Values 15 43 11 44
[176]
ref_hepatocyte LY96
Mean 2.98
Standard deviation 1.7
Values 3 4.2 0 4 3.7
[177]
HepG2 LY96
Mean 1.05
Standard deviation 0.03
Values 1 1.1
[178]
HepG2.C3A LY96
Mean 0.711
Standard deviation 0.08
Values 0.77 0.65
[179]
HuH.7 LY96
Mean 0.008
Standard deviation 0.0015
Values 0.0082 0.0064 0.0094
[180]
SNU475 LY96
Mean 2.13
Standard deviation 0.56
Values 2.5 1.7
[181]
THLE LY96
Mean 0.194
Standard deviation 0.13
Values 0.1 0.29
[182]
liver LY96
Mean 1.65
Standard deviation 1.4
Values 2.6 0.6 3 0.34
[183]
ref_hepatocyte NCOA6
Mean 2.79
Standard deviation 1.7
Values 5.4 2 3.6 1.8 1.1
[184]
HepG2 NCOA6
Mean 28.5
Standard deviation 3.8
Values 26 31
[185]
HepG2.C3A NCOA6
Mean 22.8
Standard deviation 5.6
Values 27 19
[186]
HuH.7 NCOA6
Mean 25.3
Standard deviation 5.4
Values 28 28 19
[187]
SNU475 NCOA6
Mean 30.3
Standard deviation 1.8
Values 29 32
[188]
THLE NCOA6
Mean 20.2
Standard deviation 3.3
Values 18 22
[189]
liver NCOA6
Mean 10.5
Standard deviation 4.7
Values 15 6.1 14 6.9
[190]
ref_hepatocyte EP300
Mean 2.46
Standard deviation 1.2
Values 3 1.8 4.4 1.4 1.8
[191]
HepG2 EP300
Mean 35.9
Standard deviation 5.7
Values 32 40
[192]
HepG2.C3A EP300
Mean 24.1
Standard deviation 1.4
Values 23 25
[193]
HuH.7 EP300
Mean 43
Standard deviation 15
Values 55 48 26
[194]
SNU475 EP300
Mean 26.9
Standard deviation 1.3
Values 28 26
[195]
THLE EP300
Mean 31.2
Standard deviation 11
Values 23 39
[196]
liver EP300
Mean 23.6
Standard deviation 8
Values 20 27 15 33
[197]
ref_hepatocyte MEF2D
Mean 2.42
Standard deviation 1.9
Values 1.3 2 5.7 2 1.1
[198]
HepG2 MEF2D
Mean 8.93
Standard deviation 2.6
Values 11 7.1
[199]
HepG2.C3A MEF2D
Mean 7.23
Standard deviation 3.9
Values 10 4.5
[200]
HuH.7 MEF2D
Mean 11.4
Standard deviation 3.5
Values 11 15 8.3
[201]
SNU475 MEF2D
Mean 26.5
Standard deviation 1.1
Values 26 27
[202]
THLE MEF2D
Mean 22.2
Standard deviation 2.9
Values 20 24
[203]
liver MEF2D
Mean 6.21
Standard deviation 0.85
Values 6.3 5 6.7 6.9
[204]
ref_hepatocyte TGS1
Mean 2.21
Standard deviation 0.84
Values 1.9 3.3 2.8 1.3 1.7
[205]
HepG2 TGS1
Mean 7.35
Standard deviation 1.5
Values 6.3 8.4
[206]
HepG2.C3A TGS1
Mean 8.89
Standard deviation 3.1
Values 6.7 11
[207]
HuH.7 TGS1
Mean 12.4
Standard deviation 1.5
Values 14 11 13
[208]
SNU475 TGS1
Mean 13.3
Standard deviation 0.35
Values 13 14
[209]
THLE TGS1
Mean 13.3
Standard deviation 0.95
Values 13 14
[210]
liver TGS1
Mean 6.17
Standard deviation 1.7
Values 5.2 8.4 4.7 6.3
[211]
ref_hepatocyte NCOA1
Mean 2.09
Standard deviation 0.73
Values 1.8 2 1.1 2.8 2.8
[212]
HepG2 NCOA1
Mean 6.38
Standard deviation 1.4
Values 5.4 7.4
[213]
HepG2.C3A NCOA1
Mean 8.42
Standard deviation 0.79
Values 7.9 9
[214]
HuH.7 NCOA1
Mean 9.25
Standard deviation 2.7
Values 9.2 12 6.6
[215]
SNU475 NCOA1
Mean 13.3
Standard deviation 1
Values 14 13
[216]
THLE NCOA1
Mean 10.2
Standard deviation 0.47
Values 9.9 11
[217]
liver NCOA1
Mean 18.7
Standard deviation 4.8
Values 17 23 13 22
[218]
ref_hepatocyte PPARGC1A
Mean 1.87
Standard deviation 1.7
Values 4 0.26 0.25 3.2 1.6
[219]
HepG2 PPARGC1A
Mean 1.94
Standard deviation 0.37
Values 1.7 2.2
[220]
HepG2.C3A PPARGC1A
Mean 12.8
Standard deviation 3.6
Values 15 10
[221]
HuH.7 PPARGC1A
Mean 0.00701
Standard deviation 0.0065
Values 0.0082 0.013 0
[222]
SNU475 PPARGC1A
Mean 5.83
Standard deviation 1.4
Values 6.8 4.9
[223]
THLE PPARGC1A
Mean 0.662
Standard deviation 0.1
Values 0.73 0.59
[224]
liver PPARGC1A
Mean 28.7
Standard deviation 18
Values 20 54 15 26
[225]
ref_hepatocyte SIRT1
Mean 1.83
Standard deviation 0.67
Values 2.9 1.6 1.2 1.4 2
[226]
HepG2 SIRT1
Mean 5.71
Standard deviation 1.4
Values 4.7 6.7
[227]
HepG2.C3A SIRT1
Mean 10.9
Standard deviation 1
Values 10 12
[228]
HuH.7 SIRT1
Mean 7.67
Standard deviation 1.5
Values 7.5 9.3 6.3
[229]
SNU475 SIRT1
Mean 9.92
Standard deviation 1.6
Values 8.8 11
[230]
THLE SIRT1
Mean 13.2
Standard deviation 0.39
Values 13 13
[231]
liver SIRT1
Mean 6.57
Standard deviation 1.6
Values 7.9 6.2 4.4 7.7
[232]
ref_hepatocyte CREB1
Mean 1.8
Standard deviation 1.2
Values 3.7 2.1 1.5 0.96 0.81
[233]
HepG2 CREB1
Mean 13.1
Standard deviation 2.8
Values 11 15
[234]
HepG2.C3A CREB1
Mean 26.1
Standard deviation 3.2
Values 24 28
[235]
HuH.7 CREB1
Mean 35.1
Standard deviation 4
Values 38 36 31
[236]
SNU475 CREB1
Mean 19.3
Standard deviation 0.081
Values 19 19
[237]
THLE CREB1
Mean 20.8
Standard deviation 2.1
Values 22 19
[238]
liver CREB1
Mean 13
Standard deviation 3.1
Values 12 16 9.3 15
[239]
ref_hepatocyte CREBBP
Mean 1.78
Standard deviation 0.69
Values 1.8 0.72 2.6 1.9 1.9
[240]
HepG2 CREBBP
Mean 29.3
Standard deviation 2.8
Values 27 31
[241]
HepG2.C3A CREBBP
Mean 15.2
Standard deviation 1
Values 16 14
[242]
HuH.7 CREBBP
Mean 22.2
Standard deviation 7.2
Values 28 24 14
[243]
SNU475 CREBBP
Mean 22.1
Standard deviation 0.2
Values 22 22
[244]
THLE CREBBP
Mean 24.9
Standard deviation 7.3
Values 20 30
[245]
liver CREBBP
Mean 23.8
Standard deviation 6
Values 30 21 17 28
[246]
ref_hepatocyte CLOCK
Mean 1.77
Standard deviation 1.8
Values 1.2 4.8 2.2 0.53 0.24
[247]
HepG2 CLOCK
Mean 6.74
Standard deviation 3.1
Values 4.6 8.9
[248]
HepG2.C3A CLOCK
Mean 13.9
Standard deviation 3.4
Values 11 16
[249]
HuH.7 CLOCK
Mean 11.2
Standard deviation 3.9
Values 12 15 7.1
[250]
SNU475 CLOCK
Mean 16.5
Standard deviation 0.94
Values 16 17
[251]
THLE CLOCK
Mean 28.4
Standard deviation 2.1
Values 30 27
[252]
liver CLOCK
Mean 27.1
Standard deviation 6.8
Values 24 31 19 34
[253]
ref_hepatocyte CRTC3
Mean 1.63
Standard deviation 0.77
Values 1.5 0.52 2.5 2.2 1.4
[254]
HepG2 CRTC3
Mean 9.38
Standard deviation 1.6
Values 10 8.3
[255]
HepG2.C3A CRTC3
Mean 6.46
Standard deviation 1.5
Values 7.5 5.4
[256]
HuH.7 CRTC3
Mean 8.16
Standard deviation 4.1
Values 6.8 13 5
[257]
SNU475 CRTC3
Mean 12.7
Standard deviation 0.6
Values 13 12
[258]
THLE CRTC3
Mean 13.4
Standard deviation 1.8
Values 12 15
[259]
liver CRTC3
Mean 5.67
Standard deviation 1
Values 5 6.1 4.7 6.9
[260]
ref_hepatocyte RORA
Mean 1.62
Standard deviation 0.21
Values 1.6 1.4 2 1.5 1.6
[261]
HepG2 RORA
Mean 4.37
Standard deviation 1.2
Values 3.5 5.2
[262]
HepG2.C3A RORA
Mean 17.7
Standard deviation 3.8
Values 20 15
[263]
HuH.7 RORA
Mean 4.91
Standard deviation 5.8
Values 2.1 12 1.1
[264]
SNU475 RORA
Mean 0.325
Standard deviation 0.18
Values 0.2 0.45
[265]
THLE RORA
Mean 0.957
Standard deviation 0.34
Values 1.2 0.72
[266]
liver RORA
Mean 46.9
Standard deviation 25
Values 29 68 22 69
[267]
ref_hepatocyte CHD9
Mean 1.2
Standard deviation 0.54
Values 2 1.4 0.73 0.67 1.2
[268]
HepG2 CHD9
Mean 6.61
Standard deviation 1.9
Values 5.3 7.9
[269]
HepG2.C3A CHD9
Mean 25.2
Standard deviation 3.6
Values 23 28
[270]
HuH.7 CHD9
Mean 14.3
Standard deviation 7.3
Values 14 22 7.2
[271]
SNU475 CHD9
Mean 11.4
Standard deviation 0.14
Values 12 11
[272]
THLE CHD9
Mean 25.9
Standard deviation 7.7
Values 31 20
[273]
liver CHD9
Mean 51.7
Standard deviation 20
Values 38 76 33 59
[274]
ref_hepatocyte NCOA2
Mean 1.14
Standard deviation 0.47
Values 1.5 1.7 1.2 0.47 0.91
[275]
HepG2 NCOA2
Mean 7.51
Standard deviation 4.4
Values 4.4 11
[276]
HepG2.C3A NCOA2
Mean 11.8
Standard deviation 4.3
Values 8.7 15
[277]
HuH.7 NCOA2
Mean 40.1
Standard deviation 18
Values 55 45 21
[278]
SNU475 NCOA2
Mean 19.2
Standard deviation 3.8
Values 22 17
[279]
THLE NCOA2
Mean 6.6
Standard deviation 1.4
Values 5.6 7.6
[280]
liver NCOA2
Mean 39.3
Standard deviation 20
Values 25 56 20 57
[281]
ref_hepatocyte USP46
Mean 0.954
Standard deviation 0.66
Values 2 1.2 0.56 0.53 0.46
[282]
HepG2 USP46
Mean 9.83
Standard deviation 3.3
Values 7.5 12
[283]
HepG2.C3A USP46
Mean 7.79
Standard deviation 1.8
Values 6.5 9.1
[284]
HuH.7 USP46
Mean 21.3
Standard deviation 2.6
Values 24 20 20
[285]
SNU475 USP46
Mean 7.99
Standard deviation 0.78
Values 8.5 7.4
[286]
THLE USP46
Mean 12.7
Standard deviation 0.8
Values 12 13
[287]
liver USP46
Mean 5.89
Standard deviation 1.3
Values 3.9 6.6 6.5 6.6
[288]
ref_hepatocyte CLEC1B
Mean 0.818
Standard deviation 1.3
Values 0 0 0 3 1.1
[289]
HepG2 CLEC1B
Mean 0
Standard deviation 0
Values 0 0
[290]
HepG2.C3A CLEC1B
Mean 0
Standard deviation 0
Values 0 0
[291]
HuH.7 CLEC1B
Mean 0
Standard deviation 0
Values 0 0 0
[292]
SNU475 CLEC1B
Mean 0.00717
Standard deviation 0.003
Values 0.0093 0.0051
[293]
THLE CLEC1B
Mean 0
Standard deviation 0
Values 0 0
[294]
liver CLEC1B
Mean 10
Standard deviation 5.3
Values 13 6.5 16 4.7
[295]
ref_hepatocyte RAI1
Mean 0.617
Standard deviation 0.33
Values 1 0.5 0.92 0.37 0.28
[296]
HepG2 RAI1
Mean 21.4
Standard deviation 4
Values 24 19
[297]
HepG2.C3A RAI1
Mean 12.2
Standard deviation 2.3
Values 14 11
[298]
HuH.7 RAI1
Mean 13.4
Standard deviation 2.7
Values 17 12 12
[299]
SNU475 RAI1
Mean 26.1
Standard deviation 5
Values 30 23
[300]
THLE RAI1
Mean 20.7
Standard deviation 2.2
Values 19 22
[301]
liver RAI1
Mean 3.97
Standard deviation 2.4
Values 1.6 5.3 2.4 6.6
[302]
ref_hepatocyte TLR4
Mean 0.547
Standard deviation 0.41
Values 0 1.1 0.33 0.64 0.66
[303]
HepG2 TLR4
Mean 1.46
Standard deviation 0.9
Values 0.82 2.1
[304]
HepG2.C3A TLR4
Mean 0.0365
Standard deviation 0.024
Values 0.019 0.054
[305]
HuH.7 TLR4
Mean 0.0189
Standard deviation 0.019
Values 0 0.019 0.037
[306]
SNU475 TLR4
Mean 0.0293
Standard deviation 0.0087
Values 0.023 0.035
[307]
THLE TLR4
Mean 45
Standard deviation 10
Values 52 38
[308]
liver TLR4
Mean 17.2
Standard deviation 6.3
Values 13 19 11 25
[309]
ref_hepatocyte CRTC1
Mean 0.39
Standard deviation 0.23
Values 0.46 0.034 0.34 0.64 0.48
[310]
HepG2 CRTC1
Mean 5.58
Standard deviation 0.44
Values 5.9 5.3
[311]
HepG2.C3A CRTC1
Mean 7.08
Standard deviation 3.2
Values 9.3 4.8
[312]
HuH.7 CRTC1
Mean 14.2
Standard deviation 0.84
Values 15 14 13
[313]
SNU475 CRTC1
Mean 3.77
Standard deviation 0.62
Values 4.2 3.3
[314]
THLE CRTC1
Mean 3.58
Standard deviation 0.49
Values 3.9 3.2
[315]
liver CRTC1
Mean 2.14
Standard deviation 0.5
Values 2.7 1.7 1.7 2.4
[316]
ref_hepatocyte SMARCD3
Mean 0.295
Standard deviation 0.37
Values 0.14 0 0 0.84 0.49
[317]
HepG2 SMARCD3
Mean 1.81
Standard deviation 0.37
Values 2.1 1.5
[318]
HepG2.C3A SMARCD3
Mean 0.505
Standard deviation 0.013
Values 0.5 0.51
[319]
HuH.7 SMARCD3
Mean 2.01
Standard deviation 0.75
Values 1.2 2.7 2.1
[320]
SNU475 SMARCD3
Mean 5.2
Standard deviation 0.8
Values 5.8 4.6
[321]
THLE SMARCD3
Mean 6.62
Standard deviation 1.2
Values 7.5 5.8
[322]
liver SMARCD3
Mean 1.08
Standard deviation 0.11
Values 1.1 0.91 1.2 1.1
[323]
ref_hepatocyte MEF2C
Mean 0.12
Standard deviation 0.15
Values 0 0 0.19 0.069 0.34
[324]
HepG2 MEF2C
Mean 0.0308
Standard deviation 0.011
Values 0.023 0.039
[325]
HepG2.C3A MEF2C
Mean 0.0598
Standard deviation 0.039
Values 0.087 0.032
[326]
HuH.7 MEF2C
Mean 1.79
Standard deviation 0.19
Values 2 1.8 1.6
[327]
SNU475 MEF2C
Mean 10.8
Standard deviation 1
Values 10 12
[328]
THLE MEF2C
Mean 0.747
Standard deviation 0.16
Values 0.63 0.86
[329]
liver MEF2C
Mean 6.67
Standard deviation 1.2
Values 7.3 8 6 5.4
[330]
ref_hepatocyte HELZ2
Missing
[331]
HepG2 HELZ2
Mean 28.7
Standard deviation 16
Values 40 17
[332]
HepG2.C3A HELZ2
Mean 8.75
Standard deviation 4.4
Values 12 5.6
[333]
HuH.7 HELZ2
Mean 17.6
Standard deviation 3.8
Values 19 20 13
[334]
SNU475 HELZ2
Mean 16
Standard deviation 2
Values 17 15
[335]
THLE HELZ2
Mean 13.8
Standard deviation 0.66
Values 14 13
[336]
liver HELZ2
Mean 14.6
Standard deviation 11
Values 5.9 24 3.5 25