REACTOME_HDR_THROUGH_MMEJ_ALT_NHEJ Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 PARP1 Poly [ADP-ribose] polymerase 1 [1] -0.20[2] -0.72[3] -0.41[4] -0.23[5] -0.71[6] -0.49[7]
2 PARP2 Poly [ADP-ribose] polymerase 2 [8] -0.40[9] -1.05[10] -0.72[11] -1.03[12] -0.25[13] -1.55[14]
3 FEN1 Flap endonuclease 1 [15] 0.70[16] 0.21[17] 0.64[18] -0.08[19] 0.83[20] -1.17[21]
4 NBN Nibrin [22] -0.75[23] 0.16[24] -0.52[25] 0.75[26] -0.13[27] 1.19[28]
5 RAD50 DNA repair protein RAD50 [29] -0.18[30] 1.68[31] 0.40[32] 0.51[33] 1.01[34] 2.13[35]
6 XRCC1 DNA repair protein XRCC1 [36] 0.31[37] 0.22[38] 0.87[39] 0.01[40] 0.00[41] -1.00[42]
7 RBBP8 DNA endonuclease RBBP8 [43] -0.14[44] 1.00[45] -0.80[46] 0.68[47] 0.89[48] 0.17[49]
8 LIG3 DNA ligase 3 [50] 0.85[51] 0.62[52] 1.26[53] 0.32[54] -0.62[55] 0.79[56]
9 POLQ DNA polymerase theta [57] 2.14[58] 2.93[59] 2.87[60] 2.60[61] 3.27[62] 0.43[63]
10 MRE11 Double-strand break repair protein MRE11 [64] [65] [66] [67] [68] [69] [70]
[1]
ref_hepatocyte PARP1
Mean 36.6
Standard deviation 31
Values 26 91 33 17 16
[2]
HepG2 PARP1
Mean 88.3
Standard deviation 6.6
Values 84 93
[3]
HepG2.C3A PARP1
Mean 66.3
Standard deviation 14
Values 56 76
[4]
HuH.7 PARP1
Mean 106
Standard deviation 38
Values 1.3e+02 62 1.3e+02
[5]
SNU475 PARP1
Mean 96.8
Standard deviation 5.2
Values 1e+02 93
[6]
THLE PARP1
Mean 77.5
Standard deviation 13
Values 68 87
[7]
liver PARP1
Mean 39.1
Standard deviation 10
Values 31 44 51 31
[8]
ref_hepatocyte PARP2
Mean 9.38
Standard deviation 6.1
Values 15 17 5.5 4.8 4.6
[9]
HepG2 PARP2
Mean 19.7
Standard deviation 5.2
Values 16 23
[10]
HepG2.C3A PARP2
Mean 13.6
Standard deviation 4
Values 11 16
[11]
HuH.7 PARP2
Mean 22
Standard deviation 9.2
Values 24 12 30
[12]
SNU475 PARP2
Mean 14.2
Standard deviation 3.8
Values 12 17
[13]
THLE PARP2
Mean 27.3
Standard deviation 2.1
Values 29 26
[14]
liver PARP2
Mean 4.8
Standard deviation 3.1
Values 8 2.1 6.9 2.2
[15]
ref_hepatocyte FEN1
Mean 8.88
Standard deviation 4.9
Values 17 9.6 7.8 7 3.4
[16]
HepG2 FEN1
Mean 40
Standard deviation 13
Values 31 49
[17]
HepG2.C3A FEN1
Mean 30.8
Standard deviation 20
Values 17 45
[18]
HuH.7 FEN1
Mean 53.6
Standard deviation 31
Values 63 19 79
[19]
SNU475 FEN1
Mean 26.1
Standard deviation 5.2
Values 22 30
[20]
THLE FEN1
Mean 54.6
Standard deviation 11
Values 47 62
[21]
liver FEN1
Mean 5.91
Standard deviation 2.9
Values 3.7 5.8 10 4.1
[22]
ref_hepatocyte NBN
Mean 5.99
Standard deviation 3.6
Values 7.6 11 3.9 2.7 4.3
[23]
HepG2 NBN
Mean 9.9
Standard deviation 6.3
Values 5.4 14
[24]
HepG2.C3A NBN
Mean 20
Standard deviation 9.1
Values 14 26
[25]
HuH.7 NBN
Mean 16.2
Standard deviation 4.2
Values 20 12 17
[26]
SNU475 NBN
Mean 31.2
Standard deviation 0.96
Values 30 32
[27]
THLE NBN
Mean 19
Standard deviation 0.88
Values 20 18
[28]
liver NBN
Mean 20.5
Standard deviation 4.2
Values 19 24 24 16
[29]
ref_hepatocyte RAD50
Mean 3.85
Standard deviation 2.1
Values 3.9 7.4 2.3 2.9 2.8
[30]
HepG2 RAD50
Mean 9.45
Standard deviation 2.3
Values 7.9 11
[31]
HepG2.C3A RAD50
Mean 36.9
Standard deviation 0.99
Values 38 36
[32]
HuH.7 RAD50
Mean 19.7
Standard deviation 4.1
Values 22 22 15
[33]
SNU475 RAD50
Mean 17
Standard deviation 2.2
Values 15 19
[34]
THLE RAD50
Mean 26.8
Standard deviation 8.4
Values 33 21
[35]
liver RAD50
Mean 25.2
Standard deviation 5.7
Values 32 26 25 18
[36]
ref_hepatocyte XRCC1
Mean 3.8
Standard deviation 1.2
Values 5.2 3.1 5 2.8 3
[37]
HepG2 XRCC1
Mean 13
Standard deviation 0.87
Values 12 14
[38]
HepG2.C3A XRCC1
Mean 13.2
Standard deviation 1.4
Values 14 12
[39]
HuH.7 XRCC1
Mean 26.8
Standard deviation 4.3
Values 31 22 27
[40]
SNU475 XRCC1
Mean 11.8
Standard deviation 1.2
Values 11 13
[41]
THLE XRCC1
Mean 13.1
Standard deviation 0.99
Values 12 14
[42]
liver XRCC1
Mean 2.84
Standard deviation 1.8
Values 3.7 1.7 5 1
[43]
ref_hepatocyte RBBP8
Mean 3.69
Standard deviation 1.9
Values 3.5 6.7 3.6 3.4 1.2
[44]
HepG2 RBBP8
Mean 9.31
Standard deviation 4.7
Values 6 13
[45]
HepG2.C3A RBBP8
Mean 22.1
Standard deviation 12
Values 14 31
[46]
HuH.7 RBBP8
Mean 8.18
Standard deviation 3.3
Values 9.6 4.4 10
[47]
SNU475 RBBP8
Mean 18.3
Standard deviation 4.9
Values 15 22
[48]
THLE RBBP8
Mean 23.6
Standard deviation 4.7
Values 27 20
[49]
liver RBBP8
Mean 6.21
Standard deviation 1.4
Values 8.1 5.9 6.2 4.6
[50]
ref_hepatocyte LIG3
Mean 3.12
Standard deviation 1.4
Values 3.1 3.1 5.3 2.2 1.8
[51]
HepG2 LIG3
Mean 15.6
Standard deviation 1.4
Values 15 17
[52]
HepG2.C3A LIG3
Mean 14.3
Standard deviation 1.2
Values 15 13
[53]
HuH.7 LIG3
Mean 28.9
Standard deviation 9.5
Values 36 18 32
[54]
SNU475 LIG3
Mean 12.1
Standard deviation 1.6
Values 13 11
[55]
THLE LIG3
Mean 7.01
Standard deviation 1.3
Values 6.1 7.9
[56]
liver LIG3
Mean 8.07
Standard deviation 3.2
Values 3.9 9.5 7.4 11
[57]
ref_hepatocyte POLQ
Mean 0.391
Standard deviation 0.45
Values 0.85 0.91 0.03 0.052 0.11
[58]
HepG2 POLQ
Mean 4.77
Standard deviation 3.4
Values 2.4 7.1
[59]
HepG2.C3A POLQ
Mean 8.94
Standard deviation 7.3
Values 3.8 14
[60]
HuH.7 POLQ
Mean 11
Standard deviation 5.7
Values 16 4.9 12
[61]
SNU475 POLQ
Mean 7.36
Standard deviation 2
Values 6 8.8
[62]
THLE POLQ
Mean 13.1
Standard deviation 1.3
Values 14 12
[63]
liver POLQ
Mean 0.792
Standard deviation 0.81
Values 0.4 2 0.64 0.16
[64]
ref_hepatocyte MRE11
Missing
[65]
HepG2 MRE11
Missing
[66]
HepG2.C3A MRE11
Missing
[67]
HuH.7 MRE11
Missing
[68]
SNU475 MRE11
Missing
[69]
THLE MRE11
Missing
[70]
liver MRE11
Missing