REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_CDC42 | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | CDC42 | Cell division control protein 42 homolog | [1] | -0.28[2] | 0.22[3] | -0.57[4] | -0.50[5] | -1.16[6] | -0.82[7] |
2 | GNG5 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 | -0.66[8] | -0.70[9] | -1.34[10] | -1.77[11] | -1.97[12] | -0.33[13] | |
3 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | [14] | 1.56[15] | 1.36[16] | 1.10[17] | 1.32[18] | 1.18[19] | 0.02[20] |
4 | GNB2 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 | [21] | -0.05[22] | -0.53[23] | 0.03[24] | -0.33[25] | -0.21[26] | -0.34[27] |
5 | GNG10 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 | -4.15[28] | -4.09[29] | -4.17[30] | -3.77[31] | -2.90[32] | -3.08[33] | |
6 | GNG12 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 | -4.20[34] | -7.35[35] | 0.82[36] | 1.92[37] | 2.07[38] | 1.74[39] | |
7 | GNB5 | Guanine nucleotide-binding protein subunit beta-5 | [40] | 0.65[41] | 0.46[42] | 1.71[43] | 0.83[44] | 1.01[45] | 2.15[46] |
8 | PAK1 | Serine/threonine-protein kinase PAK 1 | [47] | 0.54[48] | -0.44[49] | 2.19[50] | -1.82[51] | 2.02[52] | 1.53[53] |
9 | GNG11 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 | -7.63[54] | -7.85[55] | -6.94[56] | 2.30[57] | 3.68[58] | 3.49[59] | |
10 | GNG7 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 | 2.10[60] | 1.53[61] | 2.56[62] | -2.20[63] | -1.52[64] | 1.28[65] | |
11 | GNG4 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 | 4.02[66] | 1.56[67] | 5.58[68] | 1.29[69] | -0.76[70] | -1.29[71] | |
12 | ARHGEF6 | Rho guanine nucleotide exchange factor 6 | [72] | -5.47[73] | -3.44[74] | -3.83[75] | 3.27[76] | 1.85[77] | 4.40[78] |
13 | GNB4 | Guanine nucleotide-binding protein subunit beta-4 | [79] | 0.18[80] | 0.45[81] | 1.67[82] | 2.72[83] | 5.51[84] | 5.35[85] |
14 | GNG2 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | -5.73[86] | -6.83[87] | [88] | 3.16[89] | 2.69[90] | 4.04[91] | |
15 | GNGT2 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 | [92] | [93] | [94] | -2.03[95] | -6.64[96] | 1.37[97] | |
16 | GNG3 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 | -0.31[98] | 1.31[99] | -0.70[100] | -0.66[101] | -0.92[102] | 1.18[103] | |
17 | GNB3 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 | [104] | 2.14[105] | 4.17[106] | 3.69[107] | 1.05[108] | 3.82[109] | -0.42[110] |
18 | GNG8 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 | [111] | [112] | [113] | [114] | [115] | [116] | |
19 | GNG13 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 | [117] | [118] | [119] | [120] | [121] | [122] | |
20 | GNGT1 | Guanine nucleotide-binding protein G(T) subunit gamma-T1 | [123] | [124] | [125] | [126] | [127] | [128] | [129] |