REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | GNAS | Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas | 0.26[1] | 0.39[2] | 0.10[3] | 0.33[4] | -0.36[5] | -0.92[6] | |
2 | GNG5 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 | -1.37[7] | -1.10[8] | -1.91[9] | -2.33[10] | -2.51[11] | -1.17[12] | |
3 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | [13] | 0.85[14] | 0.96[15] | 0.53[16] | 0.76[17] | 0.64[18] | -0.82[19] |
4 | GNB2 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 | [20] | -0.77[21] | -0.93[22] | -0.54[23] | -0.89[24] | -0.75[25] | -1.18[26] |
5 | GNG10 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 | -4.87[27] | -4.49[28] | -4.74[29] | -4.33[30] | -3.43[31] | -3.92[32] | |
6 | GNAI2 | Guanine nucleotide-binding protein G(i) subunit alpha-2 | [33] | -0.10[34] | -1.07[35] | -0.85[36] | -0.69[37] | 0.46[38] | 0.23[39] |
7 | GNG12 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 | -4.92[40] | -7.76[41] | 0.24[42] | 1.36[43] | 1.54[44] | 0.90[45] | |
8 | GNAI3 | Guanine nucleotide-binding protein G(k) subunit alpha | [46] | -0.04[47] | 0.60[48] | 0.75[49] | 0.58[50] | 0.29[51] | 0.65[52] |
9 | GNAI1 | Guanine nucleotide-binding protein G(i) subunit alpha-1 | [53] | -1.81[54] | -2.66[55] | -0.47[56] | 0.70[57] | 0.15[58] | 1.25[59] |
10 | GNB5 | Guanine nucleotide-binding protein subunit beta-5 | [60] | -0.07[61] | 0.06[62] | 1.13[63] | 0.27[64] | 0.47[65] | 1.31[66] |
11 | PRKCD | Protein kinase C delta type | [67] | 0.93[68] | 1.27[69] | 0.80[70] | -1.02[71] | 0.21[72] | -0.65[73] |
12 | ADCY9 | Adenylate cyclase type 9 | [74] | 2.45[75] | 1.73[76] | 2.21[77] | 0.44[78] | 0.06[79] | 2.83[80] |
13 | PRKCA | Protein kinase C alpha type | [81] | 2.67[82] | 2.80[83] | 3.22[84] | 1.63[85] | 2.07[86] | 2.34[87] |
14 | ADCY6 | Adenylate cyclase type 6 | [88] | 1.89[89] | 2.44[90] | 2.45[91] | 1.99[92] | 2.74[93] | 3.06[94] |
15 | GNAZ | Guanine nucleotide-binding protein G(z) subunit alpha | [95] | 1.73[96] | 2.29[97] | 1.61[98] | -2.52[99] | -2.01[100] | -2.89[101] |
16 | RGS19 | Regulator of G-protein signaling 19 | [102] | 1.09[103] | 0.90[104] | -0.25[105] | 1.00[106] | -0.52[107] | 0.43[108] |
17 | GNG11 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 | -8.35[109] | -8.25[110] | -7.51[111] | 1.74[112] | 3.14[113] | 2.65[114] | |
18 | GNG7 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 | 1.39[115] | 1.13[116] | 1.99[117] | -2.76[118] | -2.05[119] | 0.44[120] | |
19 | ADRA2C | Alpha-2C adrenergic receptor | [121] | 3.85[122] | -2.46[123] | -0.76[124] | -3.76[125] | -5.40[126] | -2.81[127] |
20 | ADCY1 | Adenylate cyclase type 1 | [128] | -1.00[129] | -2.78[130] | -2.93[131] | -2.63[132] | -2.57[133] | 5.41[134] |
21 | PRKCE | Protein kinase C epsilon type | [135] | 0.48[136] | -0.94[137] | 1.60[138] | 0.46[139] | 0.90[140] | 3.98[141] |
22 | GNG4 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 | 3.30[142] | 1.16[143] | 5.01[144] | 0.74[145] | -1.30[146] | -2.13[147] | |
23 | RGS16 | Regulator of G-protein signaling 16 | [148] | -7.09[149] | [150] | -0.68[151] | -0.66[152] | -2.66[153] | -0.05[154] |
24 | PRKCH | Protein kinase C eta type | [155] | -0.53[156] | -4.25[157] | -2.55[158] | 1.76[159] | 3.46[160] | 3.53[161] |
25 | ADCY7 | Adenylate cyclase type 7 | [162] | 3.35[163] | 3.06[164] | 2.07[165] | 2.79[166] | 2.34[167] | 3.34[168] |
26 | GNB4 | Guanine nucleotide-binding protein subunit beta-4 | [169] | -0.53[170] | 0.05[171] | 1.10[172] | 2.16[173] | 4.98[174] | 4.51[175] |
27 | GNG2 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | -6.44[176] | -7.23[177] | [178] | 2.60[179] | 2.15[180] | 3.20[181] | |
28 | RGS4 | Regulator of G-protein signaling 4 | [182] | [183] | -6.85[184] | -5.59[185] | 0.96[186] | 3.98[187] | 1.32[188] |
29 | PRKCB | Protein kinase C beta type | [189] | -6.98[190] | -5.69[191] | [192] | 1.96[193] | -3.26[194] | 3.96[195] |
30 | RGS20 | Regulator of G-protein signaling 20 | [196] | 1.38[197] | 2.05[198] | 0.14[199] | 1.64[200] | 1.77[201] | -0.79[202] |
31 | GNGT2 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 | [203] | [204] | [205] | -2.59[206] | -7.18[207] | 0.53[208] | |
32 | GNG3 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 | -1.02[209] | 0.91[210] | -1.27[211] | -1.22[212] | -1.46[213] | 0.34[214] | |
33 | ADCY3 | Adenylate cyclase type 3 | [215] | 1.29[216] | 0.14[217] | 3.52[218] | 4.22[219] | 5.83[220] | 3.94[221] |
34 | ADCY2 | Adenylate cyclase type 2 | [222] | -5.55[223] | -3.52[224] | -4.73[225] | -3.25[226] | -4.29[227] | -3.70[228] |
35 | PRKCQ | Protein kinase C theta type | [229] | 0.74[230] | -2.73[231] | [232] | 1.61[233] | 3.19[234] | 2.51[235] |
36 | GNB3 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 | [236] | 1.42[237] | 3.77[238] | 3.12[239] | 0.49[240] | 3.28[241] | -1.26[242] |
37 | ADCY5 | Adenylate cyclase type 5 | [243] | -0.01[244] | 1.08[245] | 2.16[246] | 0.13[247] | 1.33[248] | 6.79[249] |
38 | PRKCG | Protein kinase C gamma type | [250] | -0.99[251] | -0.22[252] | -2.55[253] | -1.58[254] | -1.59[255] | [256] |
39 | ADRA2A | Alpha-2A adrenergic receptor | [257] | -3.31[258] | -1.73[259] | [260] | 0.82[261] | 3.60[262] | 4.41[263] |
40 | ADCY4 | Adenylate cyclase type 4 | [264] | -0.08[265] | -1.06[266] | 1.64[267] | [268] | [269] | 8.79[270] |
41 | RGS17 | Regulator of G-protein signaling 17 | [271] | [272] | [273] | [274] | [275] | [276] | [277] |
42 | GNGT1 | Guanine nucleotide-binding protein G(T) subunit gamma-T1 | [278] | [279] | [280] | [281] | [282] | [283] | [284] |
43 | ADCY8 | Adenylate cyclase type 8 | [285] | [286] | [287] | [288] | [289] | [290] | [291] |
44 | GNG13 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 | [292] | [293] | [294] | [295] | [296] | [297] | |
45 | ADRA2B | Alpha-2B adrenergic receptor | [298] | [299] | [300] | [301] | [302] | [303] | [304] |
46 | GNG8 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 | [305] | [306] | [307] | [308] | [309] | [310] | |
47 | RGSL1 | Regulator of G-protein signaling protein-like | [311] | [312] | [313] | [314] | [315] | [316] | [317] |
48 | GNAT3 | Guanine nucleotide-binding protein G(t) subunit alpha-3 | [318] | [319] | [320] | [321] | [322] | [323] | [324] |