REACTOME_GRB7_EVENTS_IN_ERBB2_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 ERBB3 Receptor tyrosine-protein kinase erbB-3 [1] -0.13[2] 0.71[3] 0.26[4] -6.11[5] -5.15[6] 0.77[7]
2 ERBB2 Receptor tyrosine-protein kinase erbB-2 [8] 0.24[9] -1.48[10] 0.20[11] 1.01[12] 1.33[13] -1.39[14]
3 GRB7 Growth factor receptor-bound protein 7 [15] 0.28[16] 0.05[17] -2.27[18] -2.89[19] -1.45[20] -1.86[21]
4 NRG1 Pro-neuregulin-1, membrane-bound isoform [22] -1.80[23] -8.47[24] -5.08[25] 1.81[26] -4.95[27] -0.77[28]
5 NRG2 Pro-neuregulin-2, membrane-bound isoform [29] [30] [31] [32] [33] [34] [35]
[1]
ref_hepatocyte ERBB3
Mean 8.22
Standard deviation 4
Values 12 3.8 4.1 11 10
[2]
HepG2 ERBB3
Mean 72.9
Standard deviation 2.6
Values 75 71
[3]
HepG2.C3A ERBB3
Mean 169
Standard deviation 42
Values 2e+02 1.4e+02
[4]
HuH.7 ERBB3
Mean 83.4
Standard deviation 7.8
Values 92 80 78
[5]
SNU475 ERBB3
Mean 0.258
Standard deviation 0.12
Values 0.18 0.34
[6]
THLE ERBB3
Mean 0.344
Standard deviation 0.05
Values 0.38 0.31
[7]
liver ERBB3
Mean 57.8
Standard deviation 20
Values 44 71 39 79
[8]
ref_hepatocyte ERBB2
Mean 6.44
Standard deviation 3.8
Values 13 3.9 4.7 3.7 7.1
[9]
HepG2 ERBB2
Mean 73.6
Standard deviation 10
Values 66 81
[10]
HepG2.C3A ERBB2
Mean 29
Standard deviation 6.9
Values 34 24
[11]
HuH.7 ERBB2
Mean 62.5
Standard deviation 7.1
Values 69 55 63
[12]
SNU475 ERBB2
Mean 28.2
Standard deviation 8.4
Values 34 22
[13]
THLE ERBB2
Mean 24.1
Standard deviation 2.7
Values 22 26
[14]
liver ERBB2
Mean 10.2
Standard deviation 3.4
Values 7.9 8.1 9.6 15
[15]
ref_hepatocyte GRB7
Mean 1.79
Standard deviation 1
Values 1.9 0.17 2.4 1.8 2.8
[16]
HepG2 GRB7
Mean 21
Standard deviation 1.2
Values 20 22
[17]
HepG2.C3A GRB7
Mean 23.3
Standard deviation 14
Values 34 13
[18]
HuH.7 GRB7
Mean 3.15
Standard deviation 1.7
Values 3.5 1.4 4.6
[19]
SNU475 GRB7
Mean 0.525
Standard deviation 0.097
Values 0.59 0.46
[20]
THLE GRB7
Mean 0.975
Standard deviation 0.065
Values 0.93 1
[21]
liver GRB7
Mean 2.04
Standard deviation 1.6
Values 4 0.68 2.5 0.89
[22]
ref_hepatocyte NRG1
Mean 1.2
Standard deviation 1
Values 0 1 2.8 1.5 0.74
[23]
HepG2 NRG1
Mean 3.35
Standard deviation 2.7
Values 1.4 5.3
[24]
HepG2.C3A NRG1
Mean 0.0424
Standard deviation 0.046
Values 0.0097 0.075
[25]
HuH.7 NRG1
Mean 0.302
Standard deviation 0.17
Values 0.16 0.49 0.25
[26]
SNU475 NRG1
Mean 9.16
Standard deviation 3.3
Values 12 6.8
[27]
THLE NRG1
Mean 0.0576
Standard deviation 0.031
Values 0.035 0.08
[28]
liver NRG1
Mean 2.92
Standard deviation 2.1
Values 1.2 5.5 3.6 1.2
[29]
ref_hepatocyte NRG2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[30]
HepG2 NRG2
Mean 0.0236
Standard deviation 0.015
Values 0.034 0.013
[31]
HepG2.C3A NRG2
Mean 0
Standard deviation 0
Values 0 0
[32]
HuH.7 NRG2
Mean 0
Standard deviation 0
Values 0 0 0
[33]
SNU475 NRG2
Mean 0.181
Standard deviation 0.12
Values 0.093 0.27
[34]
THLE NRG2
Mean 0.79
Standard deviation 0.23
Values 0.63 0.95
[35]
liver NRG2
Mean 0.0321
Standard deviation 0.024
Values 0.047 0.029 0 0.053