REACTOME_GLYOXYLATE_METABOLISM_AND_GLYCINE_DEGRADATION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 AGXT Serine--pyruvate aminotransferase [1] -6.30[2] -2.79[3] -9.29[4] -12.80[5] -14.65[6] 0.09[7]
2 GRHPR Glyoxylate reductase/hydroxypyruvate reductase [8] -0.77[9] -1.12[10] 0.20[11] -0.81[12] -0.23[13] -0.78[14]
3 NDUFAB1 Acyl carrier protein, mitochondrial [15] 0.85[16] 0.05[17] -0.54[18] -0.56[19] -0.20[20] -1.73[21]
4 ALDH4A1 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [22] 1.11[23] 2.24[24] -1.79[25] -1.15[26] -2.17[27] 0.88[28]
5 GNMT Glycine N-methyltransferase [29] -5.32[30] -4.47[31] -9.08[32] -6.56[33] -9.44[34] -1.25[35]
6 HAO1 Hydroxyacid oxidase 1 [36] -8.25[37] [38] [39] [40] [41] -0.22[42]
7 PXMP2 Peroxisomal membrane protein 2 [43] -1.98[44] -2.07[45] -2.76[46] -1.61[47] -1.12[48] -0.71[49]
8 GOT2 Aspartate aminotransferase, mitochondrial [50] 1.68[51] 0.64[52] 1.12[53] 1.01[54] 2.04[55] 0.66[56]
9 PDHB Pyruvate dehydrogenase E1 component subunit beta, mitochondrial [57] 0.26[58] 0.50[59] -0.13[60] 0.53[61] 1.03[62] -1.05[63]
10 GCSH Glycine cleavage system H protein, mitochondrial [64] 0.49[65] 0.94[66] 1.26[67] 0.25[68] 0.32[69] -0.50[70]
11 DLD Dihydrolipoyl dehydrogenase, mitochondrial [71] 0.96[72] 1.07[73] 1.20[74] 2.47[75] 1.92[76] 0.03[77]
12 PRODH2 Hydroxyproline dehydrogenase [78] -1.67[79] 0.51[80] -2.56[81] -10.80[82] -9.41[83] 0.08[84]
13 PDHA1 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial 1.31[85] 0.70[86] 2.02[87] 2.21[88] 1.72[89] 0.09[90]
14 AGXT2 Alanine--glyoxylate aminotransferase 2, mitochondrial [91] -7.58[92] -9.08[93] 0.48[94] -7.88[95] -9.35[96] 0.15[97]
15 GLDC Glycine dehydrogenase (decarboxylating), mitochondrial [98] 2.31[99] 1.07[100] 2.25[101] -5.69[102] -4.82[103] 0.33[104]
16 BCKDHA 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial [105] 0.28[106] 0.02[107] 1.64[108] 0.85[109] 0.96[110] 0.34[111]
17 DLST Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial 2.55[112] 2.46[113] 1.69[114] 3.05[115] 3.14[116] -0.62[117]
18 AMT Aminomethyltransferase, mitochondrial [118] 1.58[119] 1.43[120] 2.66[121] -2.92[122] -2.03[123] -0.45[124]
19 DHTKD1 Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial 0.49[125] 0.13[126] 1.71[127] 2.38[128] 0.92[129] 2.40[130]
20 BCKDHB 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial [131] -0.35[132] -0.36[133] 1.11[134] 1.03[135] 0.29[136] 0.87[137]
21 HOGA1 4-hydroxy-2-oxoglutarate aldolase, mitochondrial [138] -0.40[139] 0.15[140] -3.03[141] -2.81[142] -2.32[143] 0.14[144]
22 PDHX Pyruvate dehydrogenase protein X component, mitochondrial [145] 1.53[146] 1.94[147] 2.19[148] 2.49[149] 1.85[150] 0.09[151]
23 DAO D-amino-acid oxidase [152] -2.08[153] -2.57[154] -3.22[155] -10.17[156] [157] -0.04[158]
24 OGDH 2-oxoglutarate dehydrogenase, mitochondrial [159] 2.84[160] 1.63[161] 2.82[162] 3.79[163] 3.70[164] 1.22[165]
25 DLAT Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial 2.91[166] 2.13[167] 2.89[168] 3.75[169] 3.25[170] 0.29[171]
26 DDO D-aspartate oxidase [172] 0.36[173] -1.98[174] -5.97[175] -0.69[176] -0.89[177] -0.76[178]
27 LIAS Lipoyl synthase, mitochondrial [179] 1.08[180] 1.79[181] 2.47[182] 1.98[183] 2.11[184] -0.48[185]
28 DBT Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial 2.61[186] 2.74[187] 4.52[188] 4.43[189] 4.10[190] 2.99[191]
29 LIPT1 Lipoyltransferase 1, mitochondrial [192] 0.58[193] 1.34[194] 2.15[195] 1.64[196] 0.93[197] -0.98[198]
30 LIPT2 Putative lipoyltransferase 2, mitochondrial [199] 2.18[200] 1.53[201] 2.25[202] 2.53[203] 2.13[204] 1.23[205]
31 PDHA2 Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial [206] [207] [208] [209] [210]
[1]
ref_hepatocyte AGXT
Mean 462
Standard deviation 6.3e+02
Values 3.3 1.8 63 8.8e+02 1.4e+03
[2]
HepG2 AGXT
Mean 3.04
Standard deviation 1.1
Values 2.3 3.8
[3]
HepG2.C3A AGXT
Mean 46.4
Standard deviation 31
Values 68 24
[4]
HuH.7 AGXT
Mean 0.403
Standard deviation 0.23
Values 0.21 0.65 0.36
[5]
SNU475 AGXT
Mean 0.0177
Standard deviation 0.025
Values 0 0.035
[6]
THLE AGXT
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[7]
liver AGXT
Mean 729
Standard deviation 4.3e+02
Values 1.2e+03 3.1e+02 9.9e+02 4.2e+02
[8]
ref_hepatocyte GRHPR
Mean 132
Standard deviation 1.2e+02
Values 54 65 33 1.9e+02 3.1e+02
[9]
HepG2 GRHPR
Mean 39.9
Standard deviation 1.2
Values 41 39
[10]
HepG2.C3A GRHPR
Mean 42.2
Standard deviation 5.7
Values 46 38
[11]
HuH.7 GRHPR
Mean 82.2
Standard deviation 15
Values 77 71 99
[12]
SNU475 GRHPR
Mean 20.5
Standard deviation 4.5
Values 24 17
[13]
THLE GRHPR
Mean 35
Standard deviation 2
Values 34 36
[14]
liver GRHPR
Mean 113
Standard deviation 66
Values 2e+02 48 98 1e+02
[15]
ref_hepatocyte NDUFAB1
Mean 88.6
Standard deviation 32
Values 90 84 38 1.2e+02 1.2e+02
[16]
HepG2 NDUFAB1
Mean 82.6
Standard deviation 12
Values 74 91
[17]
HepG2.C3A NDUFAB1
Mean 63.8
Standard deviation 17
Values 52 76
[18]
HuH.7 NDUFAB1
Mean 33.3
Standard deviation 14
Values 35 18 47
[19]
SNU475 NDUFAB1
Mean 16.4
Standard deviation 0.51
Values 16 17
[20]
THLE NDUFAB1
Mean 24.1
Standard deviation 4.5
Values 21 27
[21]
liver NDUFAB1
Mean 39.5
Standard deviation 40
Values 78 5.9 70 4.2
[22]
ref_hepatocyte ALDH4A1
Mean 76.6
Standard deviation 93
Values 7.7 17 7.4 1.4e+02 2.1e+02
[23]
HepG2 ALDH4A1
Mean 85.5
Standard deviation 16
Values 74 96
[24]
HepG2.C3A ALDH4A1
Mean 251
Standard deviation 61
Values 2.9e+02 2.1e+02
[25]
HuH.7 ALDH4A1
Mean 12.1
Standard deviation 3.6
Values 14 8 14
[26]
SNU475 ALDH4A1
Mean 9.43
Standard deviation 4.6
Values 13 6.2
[27]
THLE ALDH4A1
Mean 5.31
Standard deviation 0.91
Values 4.7 6
[28]
liver ALDH4A1
Mean 209
Standard deviation 57
Values 2.6e+02 1.5e+02 2.5e+02 1.7e+02
[29]
ref_hepatocyte GNMT
Mean 73.6
Standard deviation 1.2e+02
Values 2.1 0.55 3.7 81 2.8e+02
[30]
HepG2 GNMT
Mean 0.952
Standard deviation 0.94
Values 0.29 1.6
[31]
HepG2.C3A GNMT
Mean 2.32
Standard deviation 0.99
Values 3 1.6
[32]
HuH.7 GNMT
Mean 0.0743
Standard deviation 0.035
Values 0.066 0.045 0.11
[33]
SNU475 GNMT
Mean 0.213
Standard deviation 0.079
Values 0.27 0.16
[34]
THLE GNMT
Mean 0.0331
Standard deviation 0.013
Values 0.024 0.043
[35]
liver GNMT
Mean 46
Standard deviation 29
Values 77 18 65 25
[36]
ref_hepatocyte HAO1
Mean 66.1
Standard deviation 88
Values 0 10 5.6 1.2e+02 2e+02
[37]
HepG2 HAO1
Mean 0.112
Standard deviation 0.078
Values 0.057 0.17
[38]
HepG2.C3A HAO1
Mean 0
Standard deviation 0
Values 0 0
[39]
HuH.7 HAO1
Mean 0
Standard deviation 0
Values 0 0 0
[40]
SNU475 HAO1
Mean 0
Standard deviation 0
Values 0 0
[41]
THLE HAO1
Mean 0
Standard deviation 0
Values 0 0
[42]
liver HAO1
Mean 84
Standard deviation 33
Values 1.3e+02 74 81 52
[43]
ref_hepatocyte PXMP2
Mean 58.2
Standard deviation 73
Values 5 6.8 12 98 1.7e+02
[44]
HepG2 PXMP2
Mean 7.67
Standard deviation 0.28
Values 7.5 7.9
[45]
HepG2.C3A PXMP2
Mean 9.67
Standard deviation 4.1
Values 6.8 13
[46]
HuH.7 PXMP2
Mean 4.69
Standard deviation 2.4
Values 4.7 2.2 7.1
[47]
SNU475 PXMP2
Mean 5.23
Standard deviation 2
Values 6.6 3.8
[48]
THLE PXMP2
Mean 8.34
Standard deviation 0.87
Values 7.7 9
[49]
liver PXMP2
Mean 52.9
Standard deviation 44
Values 1e+02 16 79 16
[50]
ref_hepatocyte GOT2
Mean 58.1
Standard deviation 35
Values 32 39 29 86 1e+02
[51]
HepG2 GOT2
Mean 96.4
Standard deviation 0.81
Values 96 97
[52]
HepG2.C3A GOT2
Mean 63.2
Standard deviation 7.6
Values 58 69
[53]
HuH.7 GOT2
Mean 69
Standard deviation 13
Values 80 55 72
[54]
SNU475 GOT2
Mean 31.9
Standard deviation 2.4
Values 34 30
[55]
THLE GOT2
Mean 74.4
Standard deviation 6.4
Values 70 79
[56]
liver GOT2
Mean 136
Standard deviation 87
Values 1.8e+02 77 2.4e+02 50
[57]
ref_hepatocyte PDHB
Mean 48.5
Standard deviation 30
Values 75 85 15 35 33
[58]
HepG2 PDHB
Mean 30
Standard deviation 6.5
Values 25 35
[59]
HepG2.C3A PDHB
Mean 47.6
Standard deviation 2.1
Values 49 46
[60]
HuH.7 PDHB
Mean 24.2
Standard deviation 4.2
Values 24 20 28
[61]
SNU475 PDHB
Mean 19.1
Standard deviation 2.2
Values 21 18
[62]
THLE PDHB
Mean 30.9
Standard deviation 4.1
Values 28 34
[63]
liver PDHB
Mean 34.7
Standard deviation 25
Values 62 15 50 12
[64]
ref_hepatocyte GCSH
Mean 42.4
Standard deviation 27
Values 31 34 11 52 84
[65]
HepG2 GCSH
Mean 30.8
Standard deviation 2.7
Values 29 33
[66]
HepG2.C3A GCSH
Mean 56.6
Standard deviation 19
Values 43 70
[67]
HuH.7 GCSH
Mean 55.3
Standard deviation 22
Values 56 33 76
[68]
SNU475 GCSH
Mean 13.8
Standard deviation 2.7
Values 16 12
[69]
THLE GCSH
Mean 16.5
Standard deviation 3.6
Values 14 19
[70]
liver GCSH
Mean 44.6
Standard deviation 36
Values 71 16 80 11
[71]
ref_hepatocyte DLD
Mean 31.7
Standard deviation 25
Values 39 73 13 16 19
[72]
HepG2 DLD
Mean 31.9
Standard deviation 11
Values 24 39
[73]
HepG2.C3A DLD
Mean 46.4
Standard deviation 13
Values 37 56
[74]
HuH.7 DLD
Mean 39.8
Standard deviation 5.6
Values 44 33 43
[75]
SNU475 DLD
Mean 48.2
Standard deviation 1.7
Values 49 47
[76]
THLE DLD
Mean 37.3
Standard deviation 2.8
Values 35 39
[77]
liver DLD
Mean 47.9
Standard deviation 25
Values 56 37 79 20
[78]
ref_hepatocyte PRODH2
Mean 31.6
Standard deviation 34
Values 14 5.4 2.2 65 71
[79]
HepG2 PRODH2
Mean 5.15
Standard deviation 0.96
Values 4.5 5.8
[80]
HepG2.C3A PRODH2
Mean 31.3
Standard deviation 11
Values 39 24
[81]
HuH.7 PRODH2
Mean 2.92
Standard deviation 1.6
Values 2.8 1.4 4.6
[82]
SNU475 PRODH2
Mean 0.00485
Standard deviation 0.0003
Values 0.0046 0.0051
[83]
THLE PRODH2
Mean 0.0145
Standard deviation 0.013
Values 0.024 0.0053
[84]
liver PRODH2
Mean 49.5
Standard deviation 29
Values 85 26 61 26
[85]
ref_hepatocyte PDHA1
Mean 24.9
Standard deviation 8.4
Values 25 38 16 25 20
[86]
HepG2 PDHA1
Mean 32
Standard deviation 3.7
Values 29 35
[87]
HepG2.C3A PDHA1
Mean 28.2
Standard deviation 0.42
Values 28 28
[88]
HuH.7 PDHA1
Mean 55
Standard deviation 18
Values 64 34 67
[89]
SNU475 PDHA1
Mean 31.4
Standard deviation 0.34
Values 32 31
[90]
THLE PDHA1
Mean 25.6
Standard deviation 3
Values 24 28
[91]
liver PDHA1
Mean 39.1
Standard deviation 23
Values 54 22 63 17
[92]
ref_hepatocyte AGXT2
Mean 23.4
Standard deviation 33
Values 0 0.88 1.4 43 72
[93]
HepG2 AGXT2
Mean 0.0637
Standard deviation 0.05
Values 0.029 0.099
[94]
HepG2.C3A AGXT2
Mean 0.0302
Standard deviation 0.012
Values 0.039 0.021
[95]
HuH.7 AGXT2
Mean 17.8
Standard deviation 1.5
Values 16 18 19
[96]
SNU475 AGXT2
Mean 0.0272
Standard deviation 0.019
Values 0.014 0.041
[97]
THLE AGXT2
Mean 0.0112
Standard deviation 0.00084
Values 0.012 0.011
[98]
liver AGXT2
Mean 38.5
Standard deviation 15
Values 50 25 54 25
[99]
ref_hepatocyte GLDC
Mean 22.4
Standard deviation 12
Values 16 20 6.8 33 36
[100]
HepG2 GLDC
Mean 57.4
Standard deviation 17
Values 45 70
[101]
HepG2.C3A GLDC
Mean 32.7
Standard deviation 7.7
Values 27 38
[102]
HuH.7 GLDC
Mean 58.1
Standard deviation 14
Values 67 42 65
[103]
SNU475 GLDC
Mean 0.119
Standard deviation 0.004
Values 0.12 0.12
[104]
THLE GLDC
Mean 0.246
Standard deviation 0.0053
Values 0.24 0.25
[105]
liver GLDC
Mean 41.7
Standard deviation 17
Values 21 50 36 60
[106]
ref_hepatocyte BCKDHA
Mean 21.2
Standard deviation 23
Values 2.1 5.2 7 48 43
[107]
HepG2 BCKDHA
Mean 13.3
Standard deviation 4.2
Values 16 10
[108]
HepG2.C3A BCKDHA
Mean 15
Standard deviation 6.3
Values 19 10
[109]
HuH.7 BCKDHA
Mean 35.9
Standard deviation 11
Values 42 24 42
[110]
SNU475 BCKDHA
Mean 10.4
Standard deviation 2.4
Values 12 8.7
[111]
THLE BCKDHA
Mean 12.9
Standard deviation 0.022
Values 13 13
[112]
liver BCKDHA
Mean 39.9
Standard deviation 28
Values 56 18 71 14
[113]
ref_hepatocyte DLST
Mean 19.4
Standard deviation 4.5
Values 12 20 24 22 19
[114]
HepG2 DLST
Mean 58.7
Standard deviation 1.6
Values 60 58
[115]
HepG2.C3A DLST
Mean 74.5
Standard deviation 3.3
Values 77 72
[116]
HuH.7 DLST
Mean 34.1
Standard deviation 5.6
Values 36 28 39
[117]
SNU475 DLST
Mean 43.8
Standard deviation 3.5
Values 46 41
[118]
THLE DLST
Mean 53.2
Standard deviation 2.1
Values 52 55
[119]
liver DLST
Mean 18.7
Standard deviation 14
Values 6.4 33 6.7 28
[120]
ref_hepatocyte AMT
Mean 14.4
Standard deviation 9.4
Values 18 5.5 5.5 15 28
[121]
HepG2 AMT
Mean 22.4
Standard deviation 2
Values 21 24
[122]
HepG2.C3A AMT
Mean 27.1
Standard deviation 1.4
Values 26 28
[123]
HuH.7 AMT
Mean 49.9
Standard deviation 15
Values 52 34 64
[124]
SNU475 AMT
Mean 0.521
Standard deviation 0.31
Values 0.74 0.3
[125]
THLE AMT
Mean 1.11
Standard deviation 0.68
Values 1.6 0.63
[126]
liver AMT
Mean 15.7
Standard deviation 10
Values 20 8.5 28 6.2
[127]
ref_hepatocyte DHTKD1
Mean 12.7
Standard deviation 14
Values 1.9 4.8 3.3 18 36
[128]
HepG2 DHTKD1
Mean 9.3
Standard deviation 0.5
Values 9.7 8.9
[129]
HepG2.C3A DHTKD1
Mean 9.71
Standard deviation 0.076
Values 9.8 9.7
[130]
HuH.7 DHTKD1
Mean 22.7
Standard deviation 3.1
Values 25 19 23
[131]
SNU475 DHTKD1
Mean 18.2
Standard deviation 3.3
Values 20 16
[132]
THLE DHTKD1
Mean 7.53
Standard deviation 1.2
Values 6.7 8.4
[133]
liver DHTKD1
Mean 99.9
Standard deviation 9.7
Values 97 1.1e+02 1.1e+02 88
[134]
ref_hepatocyte BCKDHB
Mean 12.3
Standard deviation 13
Values 6.3 7.9 1 12 34
[135]
HepG2 BCKDHB
Mean 5.01
Standard deviation 1.8
Values 3.8 6.3
[136]
HepG2.C3A BCKDHB
Mean 6.65
Standard deviation 1.7
Values 5.4 7.9
[137]
HuH.7 BCKDHB
Mean 14.4
Standard deviation 4.1
Values 16 9.9 18
[138]
SNU475 BCKDHB
Mean 6.85
Standard deviation 3.3
Values 9.2 4.5
[139]
THLE BCKDHB
Mean 4.69
Standard deviation 0.33
Values 4.5 4.9
[140]
liver BCKDHB
Mean 33.2
Standard deviation 14
Values 46 26 44 18
[141]
ref_hepatocyte HOGA1
Mean 11.8
Standard deviation 7.2
Values 18 9 0.43 14 17
[142]
HepG2 HOGA1
Mean 4.63
Standard deviation 0.2
Values 4.5 4.8
[143]
HepG2.C3A HOGA1
Mean 9.08
Standard deviation 1
Values 8.4 9.8
[144]
HuH.7 HOGA1
Mean 0.785
Standard deviation 0.44
Values 0.55 1.3 0.52
[145]
SNU475 HOGA1
Mean 0.458
Standard deviation 0.15
Values 0.57 0.35
[146]
THLE HOGA1
Mean 0.733
Standard deviation 0.032
Values 0.71 0.76
[147]
liver HOGA1
Mean 19.3
Standard deviation 7.8
Values 21 18 28 9.5
[148]
ref_hepatocyte PDHX
Mean 11.4
Standard deviation 4.3
Values 15 17 6.9 8.2 10
[149]
HepG2 PDHX
Mean 17.1
Standard deviation 5.7
Values 13 21
[150]
HepG2.C3A PDHX
Mean 30.4
Standard deviation 1.9
Values 29 32
[151]
HuH.7 PDHX
Mean 28.3
Standard deviation 3.1
Values 30 25 30
[152]
SNU475 PDHX
Mean 17.6
Standard deviation 1.9
Values 16 19
[153]
THLE PDHX
Mean 12.8
Standard deviation 1.1
Values 12 14
[154]
liver PDHX
Mean 18
Standard deviation 6.9
Values 24 14 24 10
[155]
ref_hepatocyte DAO
Mean 9.8
Standard deviation 13
Values 0.74 0.44 0.56 25 23
[156]
HepG2 DAO
Mean 1.2
Standard deviation 0.36
Values 1.5 0.95
[157]
HepG2.C3A DAO
Mean 1.15
Standard deviation 0.41
Values 0.86 1.4
[158]
HuH.7 DAO
Mean 0.574
Standard deviation 0.33
Values 0.43 0.95 0.34
[159]
SNU475 DAO
Mean 0.00232
Standard deviation 0.0033
Values 0.0046 0
[160]
THLE DAO
Mean 0
Standard deviation 0
Values 0 0
[161]
liver DAO
Mean 14.1
Standard deviation 12
Values 31 5.7 9.8 9.5
[162]
ref_hepatocyte OGDH
Mean 9.59
Standard deviation 2.6
Values 6.1 11 12 11 7.8
[163]
HepG2 OGDH
Mean 35.5
Standard deviation 0.48
Values 35 36
[164]
HepG2.C3A OGDH
Mean 20.6
Standard deviation 2.9
Values 23 19
[165]
HuH.7 OGDH
Mean 37
Standard deviation 11
Values 47 26 38
[166]
SNU475 OGDH
Mean 36.2
Standard deviation 8.1
Values 42 31
[167]
THLE OGDH
Mean 38.9
Standard deviation 6
Values 35 43
[168]
liver OGDH
Mean 33.2
Standard deviation 11
Values 21 41 26 45
[169]
ref_hepatocyte DLAT
Mean 7.51
Standard deviation 3.3
Values 6.6 12 9.3 4.2 5.2
[170]
HepG2 DLAT
Mean 29.3
Standard deviation 8.9
Values 23 36
[171]
HepG2.C3A DLAT
Mean 22.9
Standard deviation 4.1
Values 20 26
[172]
HuH.7 DLAT
Mean 30.4
Standard deviation 4
Values 35 26 30
[173]
SNU475 DLAT
Mean 27.6
Standard deviation 0.023
Values 28 28
[174]
THLE DLAT
Mean 22.4
Standard deviation 2.8
Values 20 24
[175]
liver DLAT
Mean 13.6
Standard deviation 1.8
Values 13 13 16 12
[176]
ref_hepatocyte DDO
Mean 4.09
Standard deviation 0.88
Values 4.1 3.8 3 4.1 5.4
[177]
HepG2 DDO
Mean 2.73
Standard deviation 0.26
Values 2.5 2.9
[178]
HepG2.C3A DDO
Mean 0.723
Standard deviation 0.46
Values 1 0.4
[179]
HuH.7 DDO
Mean 0.0356
Standard deviation 0.032
Values 0.0082 0.071 0.028
[180]
SNU475 DDO
Mean 0.692
Standard deviation 0.25
Values 0.87 0.52
[181]
THLE DDO
Mean 0.687
Standard deviation 0.17
Values 0.8 0.57
[182]
liver DDO
Mean 3.57
Standard deviation 1.5
Values 4.6 2.7 5.1 1.9
[183]
ref_hepatocyte LIAS
Mean 3.44
Standard deviation 1.9
Values 1.9 4.1 1.1 5.4 4.7
[184]
HepG2 LIAS
Mean 3.76
Standard deviation 0.33
Values 4 3.5
[185]
HepG2.C3A LIAS
Mean 8.27
Standard deviation 0.031
Values 8.3 8.2
[186]
HuH.7 LIAS
Mean 10.4
Standard deviation 1.5
Values 8.7 11 11
[187]
SNU475 LIAS
Mean 3.73
Standard deviation 1.2
Values 2.9 4.6
[188]
THLE LIAS
Mean 4.63
Standard deviation 0.21
Values 4.5 4.8
[189]
liver LIAS
Mean 3.65
Standard deviation 1.5
Values 4.2 3.2 5.4 1.8
[190]
ref_hepatocyte DBT
Mean 2.27
Standard deviation 1.7
Values 1.9 1.5 0.89 1.9 5.2
[191]
HepG2 DBT
Mean 7.17
Standard deviation 2.1
Values 5.7 8.6
[192]
HepG2.C3A DBT
Mean 10.5
Standard deviation 1.4
Values 9.5 12
[193]
HuH.7 DBT
Mean 28.3
Standard deviation 6.2
Values 32 32 21
[194]
SNU475 DBT
Mean 13.4
Standard deviation 3.1
Values 16 11
[195]
THLE DBT
Mean 12.1
Standard deviation 0.54
Values 12 13
[196]
liver DBT
Mean 26.7
Standard deviation 4.5
Values 30 29 27 20
[197]
ref_hepatocyte LIPT1
Mean 1.7
Standard deviation 0.62
Values 1.1 1.4 2.5 1.3 2.1
[198]
HepG2 LIPT1
Mean 1.32
Standard deviation 0.3
Values 1.1 1.5
[199]
HepG2.C3A LIPT1
Mean 3.01
Standard deviation 0.22
Values 2.8 3.2
[200]
HuH.7 LIPT1
Mean 4.11
Standard deviation 0.94
Values 3.6 3.5 5.2
[201]
SNU475 LIPT1
Mean 1.45
Standard deviation 0.15
Values 1.6 1.3
[202]
THLE LIPT1
Mean 1.01
Standard deviation 0.063
Values 0.96 1.1
[203]
liver LIPT1
Mean 1.28
Standard deviation 0.54
Values 1.3 0.84 2 0.91
[204]
ref_hepatocyte LIPT2
Mean 0.395
Standard deviation 0.49
Values 0.12 0 0 0.91 0.94
[205]
HepG2 LIPT2
Mean 0.926
Standard deviation 0.036
Values 0.95 0.9
[206]
HepG2.C3A LIPT2
Mean 0.794
Standard deviation 0.091
Values 0.73 0.86
[207]
HuH.7 LIPT2
Mean 1.02
Standard deviation 0.26
Values 1.1 0.74 1.2
[208]
SNU475 LIPT2
Mean 0.623
Standard deviation 0.14
Values 0.72 0.52
[209]
THLE LIPT2
Mean 0.541
Standard deviation 0.15
Values 0.44 0.64
[210]
liver LIPT2
Mean 1.37
Standard deviation 1.1
Values 3 0.57 1.1 0.89
[211]
ref_hepatocyte PDHA2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[212]
HepG2 PDHA2
Missing
[213]
HepG2.C3A PDHA2
Missing
[214]
HuH.7 PDHA2
Missing
[215]
SNU475 PDHA2
Missing
[216]
THLE PDHA2
Missing
[217]
liver PDHA2
Missing