REACTOME_GLYCOGEN_STORAGE_DISEASES Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 UBB Polyubiquitin-B [1] -0.32[2] -0.41[3] -0.54[4] -0.36[5] -0.18[6] -0.19[7]
2 RPS27A Ubiquitin-40S ribosomal protein S27a [8] [9] [10] [11] [12] [13] [14]
3 UBC Polyubiquitin-C [15] 0.12[16] 0.34[17] -0.18[18] 0.49[19] 0.20[20] 0.26[21]
4 UBA52 Ubiquitin-60S ribosomal protein L40 [22] 2.56[23] 2.57[24] 3.33[25] 1.89[26] 2.42[27] 1.03[28]
5 GBE1 1,4-alpha-glucan-branching enzyme [29] 0.65[30] 0.99[31] -0.30[32] 1.41[33] 1.72[34] 0.97[35]
6 SLC37A4 Glucose-6-phosphate exchanger SLC37A4 [36] 0.34[37] 1.16[38] 0.76[39] 0.04[40] -0.22[41] 2.29[42]
7 PPP1R3C Protein phosphatase 1 regulatory subunit 3C [43] 0.72[44] -0.04[45] 0.06[46] 0.34[47] -0.76[48] 2.42[49]
8 GYS2 Glycogen [starch] synthase, liver [50] -9.30[51] [52] -4.72[53] [54] -8.29[55] 3.22[56]
9 GAA Lysosomal alpha-glucosidase [57] 3.93[58] 3.38[59] 3.67[60] 2.58[61] 2.90[62] 2.67[63]
10 GYG1 Glycogenin-1 [64] 1.88[65] 2.28[66] 1.53[67] 2.43[68] 2.07[69] 0.50[70]
11 GYG2 Glycogenin-2 [71] 1.09[72] 1.61[73] 3.57[74] 1.88[75] -0.27[76] 2.03[77]
12 G6PC3 Glucose-6-phosphatase 3 [78] 3.54[79] 3.25[80] 1.37[81] 3.47[82] 3.11[83] 0.40[84]
13 GYS1 Glycogen [starch] synthase, muscle [85] 5.03[86] 3.47[87] 4.43[88] 5.42[89] 5.05[90] 2.19[91]
14 EPM2A Laforin, isoform 9 [92] 1.73[93] 2.16[94] 0.33[95] 2.72[96] 1.55[97] 2.87[98]
15 NHLRC1 E3 ubiquitin-protein ligase NHLRC1 [99] -0.23[100] -4.85[101] -1.84[102] 3.03[103] 0.14[104] 2.03[105]
16 G6PC1 [106] [107] [108] [109] [110] [111] [112]
[1]
ref_hepatocyte UBB
Mean 764
Standard deviation 4.8e+02
Values 3.8e+02 3.5e+02 5.3e+02 1.2e+03 1.3e+03
[2]
HepG2 UBB
Mean 368
Standard deviation 39
Values 4e+02 3.4e+02
[3]
HepG2.C3A UBB
Mean 285
Standard deviation 14
Values 2.8e+02 3e+02
[4]
HuH.7 UBB
Mean 304
Standard deviation 40
Values 2.9e+02 2.7e+02 3.5e+02
[5]
SNU475 UBB
Mean 204
Standard deviation 3.3
Values 2.1e+02 2e+02
[6]
THLE UBB
Mean 315
Standard deviation 34
Values 2.9e+02 3.4e+02
[7]
liver UBB
Mean 296
Standard deviation 1.3e+02
Values 4.3e+02 2.1e+02 3.9e+02 1.5e+02
[8]
ref_hepatocyte RPS27A
Mean 499
Standard deviation 2.2e+02
Values 6.6e+02 6.1e+02 1.7e+02 6.8e+02 3.8e+02
[9]
HepG2 RPS27A
Missing
[10]
HepG2.C3A RPS27A
Missing
[11]
HuH.7 RPS27A
Missing
[12]
SNU475 RPS27A
Missing
[13]
THLE RPS27A
Missing
[14]
liver RPS27A
Missing
[15]
ref_hepatocyte UBC
Mean 480
Standard deviation 2.8e+02
Values 1.8e+02 3.5e+02 9.1e+02 5.8e+02 3.8e+02
[16]
HepG2 UBC
Mean 314
Standard deviation 38
Values 3.4e+02 2.9e+02
[17]
HepG2.C3A UBC
Mean 302
Standard deviation 41
Values 3.3e+02 2.7e+02
[18]
HuH.7 UBC
Mean 246
Standard deviation 64
Values 2.4e+02 3.1e+02 1.9e+02
[19]
SNU475 UBC
Mean 232
Standard deviation 63
Values 2.8e+02 1.9e+02
[20]
THLE UBC
Mean 257
Standard deviation 41
Values 2.3e+02 2.9e+02
[21]
liver UBC
Mean 254
Standard deviation 78
Values 2.2e+02 3.1e+02 3.3e+02 1.6e+02
[22]
ref_hepatocyte UBA52
Mean 57.3
Standard deviation 43
Values 14 23 49 1.2e+02 81
[23]
HepG2 UBA52
Mean 203
Standard deviation 20
Values 2.2e+02 1.9e+02
[24]
HepG2.C3A UBA52
Mean 169
Standard deviation 3.3
Values 1.7e+02 1.7e+02
[25]
HuH.7 UBA52
Mean 334
Standard deviation 46
Values 3.4e+02 2.8e+02 3.7e+02
[26]
SNU475 UBA52
Mean 72.9
Standard deviation 11
Values 65 81
[27]
THLE UBA52
Mean 144
Standard deviation 15
Values 1.3e+02 1.5e+02
[28]
liver UBA52
Mean 51.7
Standard deviation 26
Values 79 32 68 28
[29]
ref_hepatocyte GBE1
Mean 41.7
Standard deviation 56
Values 12 1.4e+02 18 13 23
[30]
HepG2 GBE1
Mean 39.4
Standard deviation 3.6
Values 42 37
[31]
HepG2.C3A GBE1
Mean 41.1
Standard deviation 4.6
Values 38 44
[32]
HuH.7 GBE1
Mean 19.6
Standard deviation 8.4
Values 15 29 14
[33]
SNU475 GBE1
Mean 38.1
Standard deviation 11
Values 46 30
[34]
THLE GBE1
Mean 64.2
Standard deviation 4.3
Values 67 61
[35]
liver GBE1
Mean 36.1
Standard deviation 10
Values 43 25 30 47
[36]
ref_hepatocyte SLC37A4
Mean 31.9
Standard deviation 40
Values 3.2 2 4.4 81 69
[37]
HepG2 SLC37A4
Mean 24.3
Standard deviation 0.11
Values 24 24
[38]
HepG2.C3A SLC37A4
Mean 35.6
Standard deviation 3.3
Values 38 33
[39]
HuH.7 SLC37A4
Mean 31.3
Standard deviation 7.3
Values 32 24 38
[40]
SNU475 SLC37A4
Mean 11.3
Standard deviation 0.43
Values 11 12
[41]
THLE SLC37A4
Mean 12.8
Standard deviation 0.78
Values 12 13
[42]
liver SLC37A4
Mean 69
Standard deviation 23
Values 89 37 79 70
[43]
ref_hepatocyte PPP1R3C
Mean 18
Standard deviation 14
Values 10 19 1 20 40
[44]
HepG2 PPP1R3C
Mean 17.9
Standard deviation 3.3
Values 16 20
[45]
HepG2.C3A PPP1R3C
Mean 8.72
Standard deviation 1.2
Values 7.9 9.6
[46]
HuH.7 PPP1R3C
Mean 10.9
Standard deviation 5.8
Values 7.5 18 7.6
[47]
SNU475 PPP1R3C
Mean 7.87
Standard deviation 3.6
Values 10 5.4
[48]
THLE PPP1R3C
Mean 4.97
Standard deviation 1.7
Values 6.1 3.8
[49]
liver PPP1R3C
Mean 42.6
Standard deviation 34
Values 91 28 39 12
[50]
ref_hepatocyte GYS2
Mean 11.3
Standard deviation 16
Values 0 1.1 1.1 17 37
[51]
HepG2 GYS2
Mean 0.0107
Standard deviation 0.015
Values 0 0.021
[52]
HepG2.C3A GYS2
Mean 0
Standard deviation 0
Values 0 0
[53]
HuH.7 GYS2
Mean 0.248
Standard deviation 0.029
Values 0.27 0.26 0.22
[54]
SNU475 GYS2
Mean 0
Standard deviation 0
Values 0 0
[55]
THLE GYS2
Mean 0.0169
Standard deviation 0.0013
Values 0.018 0.016
[56]
liver GYS2
Mean 46.5
Standard deviation 21
Values 71 33 26 56
[57]
ref_hepatocyte GAA
Mean 10.4
Standard deviation 7.9
Values 8.9 2.6 3.6 17 20
[58]
HepG2 GAA
Mean 95.6
Standard deviation 35
Values 1.2e+02 71
[59]
HepG2.C3A GAA
Mean 54.2
Standard deviation 24
Values 71 38
[60]
HuH.7 GAA
Mean 77
Standard deviation 11
Values 84 65 82
[61]
SNU475 GAA
Mean 21.5
Standard deviation 6.3
Values 26 17
[62]
THLE GAA
Mean 36.4
Standard deviation 5.3
Values 40 33
[63]
liver GAA
Mean 29.3
Standard deviation 14
Values 37 17 46 17
[64]
ref_hepatocyte GYG1
Mean 8.46
Standard deviation 4.2
Values 13 12 8.2 5.7 3.2
[65]
HepG2 GYG1
Mean 18.7
Standard deviation 2.6
Values 17 21
[66]
HepG2.C3A GYG1
Mean 20.4
Standard deviation 2.4
Values 22 19
[67]
HuH.7 GYG1
Mean 14.2
Standard deviation 0.7
Values 15 14 14
[68]
SNU475 GYG1
Mean 15.6
Standard deviation 0.8
Values 16 15
[69]
THLE GYG1
Mean 16.6
Standard deviation 2.9
Values 15 19
[70]
liver GYG1
Mean 5.27
Standard deviation 2.7
Values 7.9 2.7 7.4 3.1
[71]
ref_hepatocyte GYG2
Mean 7.7
Standard deviation 4.3
Values 12 9.2 1.1 9.5 6.4
[72]
HepG2 GYG2
Mean 9.85
Standard deviation 2.2
Values 8.3 11
[73]
HepG2.C3A GYG2
Mean 11.7
Standard deviation 0.64
Values 12 11
[74]
HuH.7 GYG2
Mean 52.9
Standard deviation 10
Values 61 42 56
[75]
SNU475 GYG2
Mean 9.78
Standard deviation 4.3
Values 13 6.8
[76]
THLE GYG2
Mean 2.99
Standard deviation 0.36
Values 3.2 2.7
[77]
liver GYG2
Mean 13.9
Standard deviation 6.8
Values 21 6.6 10 17
[78]
ref_hepatocyte G6PC3
Mean 4.81
Standard deviation 1.9
Values 7 1.8 5 5.4 4.9
[79]
HepG2 G6PC3
Mean 33.8
Standard deviation 2.2
Values 35 32
[80]
HepG2.C3A G6PC3
Mean 22.8
Standard deviation 1
Values 24 22
[81]
HuH.7 G6PC3
Mean 7.22
Standard deviation 2.9
Values 9.3 3.9 8.4
[82]
SNU475 G6PC3
Mean 18.4
Standard deviation 1.6
Values 20 17
[83]
THLE G6PC3
Mean 19.4
Standard deviation 3.3
Values 17 22
[84]
liver G6PC3
Mean 2.8
Standard deviation 1.5
Values 4.1 1.4 4 1.6
[85]
ref_hepatocyte GYS1
Mean 2
Standard deviation 0.6
Values 2.1 1.6 2.9 1.4 2
[86]
HepG2 GYS1
Mean 39.3
Standard deviation 13
Values 30 48
[87]
HepG2.C3A GYS1
Mean 11
Standard deviation 4.1
Values 8.1 14
[88]
HuH.7 GYS1
Mean 24.8
Standard deviation 7.5
Values 31 16 27
[89]
SNU475 GYS1
Mean 29.4
Standard deviation 0.52
Values 29 30
[90]
THLE GYS1
Mean 31
Standard deviation 0.41
Values 31 31
[91]
liver GYS1
Mean 4.02
Standard deviation 0.6
Values 4.1 3.2 4.6 4.1
[92]
ref_hepatocyte EPM2A
Mean 1.26
Standard deviation 1.3
Values 3.3 0.47 0 1.1 1.5
[93]
HepG2 EPM2A
Mean 2.53
Standard deviation 0.43
Values 2.2 2.8
[94]
HepG2.C3A EPM2A
Mean 2.81
Standard deviation 0.14
Values 2.9 2.7
[95]
HuH.7 EPM2A
Mean 0.917
Standard deviation 0.23
Values 1.1 0.66 0.97
[96]
SNU475 EPM2A
Mean 2.87
Standard deviation 0.47
Values 3.2 2.5
[97]
THLE EPM2A
Mean 1.73
Standard deviation 0.21
Values 1.6 1.9
[98]
liver EPM2A
Mean 4.08
Standard deviation 0.65
Values 4.4 3.7 3.4 4.9
[99]
ref_hepatocyte NHLRC1
Mean 1.24
Standard deviation 1.1
Values 0 0.38 1.8 1.2 2.8
[100]
HepG2 NHLRC1
Mean 0.636
Standard deviation 0.081
Values 0.69 0.58
[101]
HepG2.C3A NHLRC1
Mean 0.0215
Standard deviation 0.03
Values 0 0.043
[102]
HuH.7 NHLRC1
Mean 0.201
Standard deviation 0.13
Values 0.23 0.064 0.31
[103]
SNU475 NHLRC1
Mean 3.5
Standard deviation 0.023
Values 3.5 3.5
[104]
THLE NHLRC1
Mean 0.64
Standard deviation 0.027
Values 0.62 0.66
[105]
liver NHLRC1
Mean 2.24
Standard deviation 0.96
Values 3.6 1.5 2.1 1.7
[106]
ref_hepatocyte G6PC1
Missing
[107]
HepG2 G6PC1
Missing
[108]
HepG2.C3A G6PC1
Missing
[109]
HuH.7 G6PC1
Missing
[110]
SNU475 G6PC1
Missing
[111]
THLE G6PC1
Missing
[112]
liver G6PC1
Missing