REACTOME_GLUCOSE_METABOLISM |
Return to index |
|
|
|
|
|
Order |
Gene |
Description |
ref_hepatocyte |
HepG2 |
HepG2.C3A |
HuH.7 |
SNU475 |
THLE |
liver |
1 |
GAPDH |
Glyceraldehyde-3-phosphate dehydrogenase |
[1] |
-0.30[2] |
-0.46[3] |
0.31[4] |
-0.59[5] |
-0.09[6] |
-1.00[7] |
2 |
ALDOB |
Fructose-bisphosphate aldolase B |
[8] |
-11.39[9] |
-11.03[10] |
-11.07[11] |
-14.96[12] |
-15.70[13] |
0.25[14] |
3 |
ENO1 |
Alpha-enolase |
[15] |
0.46[16] |
1.01[17] |
0.15[18] |
0.58[19] |
0.08[20] |
-1.29[21] |
4 |
TPI1 |
Triosephosphate isomerase |
[22] |
-0.21[23] |
-0.23[24] |
0.35[25] |
-0.86[26] |
0.23[27] |
-0.36[28] |
5 |
PCK1 |
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] |
[29] |
-9.30[30] |
-4.96[31] |
-12.65[32] |
[33] |
-16.56[34] |
1.13[35] |
6 |
PCK2 |
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial |
[36] |
-0.83[37] |
-2.14[38] |
-1.47[39] |
-5.45[40] |
-3.17[41] |
-0.21[42] |
7 |
ALDOA |
Fructose-bisphosphate aldolase A |
[43] |
1.95[44] |
1.67[45] |
0.71[46] |
1.09[47] |
0.89[48] |
-1.11[49] |
8 |
MDH2 |
Malate dehydrogenase, mitochondrial |
[50] |
-1.35[51] |
-1.75[52] |
-1.28[53] |
-1.62[54] |
-1.93[55] |
-0.39[56] |
9 |
PGK1 |
Phosphoglycerate kinase 1 |
[57] |
1.10[58] |
0.34[59] |
0.18[60] |
1.31[61] |
0.91[62] |
-0.17[63] |
10 |
FBP1 |
Fructose-1,6-bisphosphatase 1 |
[64] |
-11.42[65] |
-9.90[66] |
-8.26[67] |
-12.49[68] |
-13.61[69] |
0.74[70] |
11 |
PGAM1 |
Phosphoglycerate mutase 1 |
[71] |
0.44[72] |
0.51[73] |
0.54[74] |
-0.19[75] |
0.58[76] |
-0.69[77] |
12 |
GOT1 |
Aspartate aminotransferase, cytoplasmic |
[78] |
-1.55[79] |
0.19[80] |
-1.38[81] |
-3.90[82] |
-2.72[83] |
0.47[84] |
13 |
MDH1 |
Malate dehydrogenase, cytoplasmic |
[85] |
-0.89[86] |
-0.19[87] |
-0.77[88] |
-0.58[89] |
-0.69[90] |
-0.51[91] |
14 |
SEC13 |
Protein SEC13 homolog |
[92] |
-1.21[93] |
-0.74[94] |
-0.57[95] |
-1.79[96] |
-1.39[97] |
-1.49[98] |
15 |
GOT2 |
Aspartate aminotransferase, mitochondrial |
[99] |
-0.67[100] |
-1.01[101] |
-0.84[102] |
-1.81[103] |
-0.50[104] |
0.79[105] |
16 |
SLC25A1 |
Tricarboxylate transport protein, mitochondrial |
[106] |
-0.70[107] |
-0.35[108] |
-0.41[109] |
-1.14[110] |
-1.67[111] |
-0.32[112] |
17 |
PC |
Pyruvate carboxylase, mitochondrial |
[113] |
-1.52[114] |
-1.22[115] |
-0.05[116] |
-1.64[117] |
-3.86[118] |
2.22[119] |
18 |
SLC37A4 |
Glucose-6-phosphate exchanger SLC37A4 |
[120] |
-1.79[121] |
-0.98[122] |
-1.12[123] |
-2.44[124] |
-2.17[125] |
0.68[126] |
19 |
PPP2R1A |
Serine/threonine-protein phosphatase
2A 65 kDa regulatory subunit A alpha isoform |
0.54[127] |
0.46[128] |
0.38[129] |
1.14[130] |
0.72[131] |
0.22[132] |
20 |
PPP2CA |
Serine/threonine-protein phosphatase
2A catalytic subunit alpha isoform |
0.02[133] |
0.21[134] |
-0.44[135] |
0.68[136] |
1.04[137] |
-0.03[138] |
21 |
GPI |
Glucose-6-phosphate isomerase |
[139] |
1.52[140] |
0.86[141] |
1.65[142] |
1.63[143] |
1.58[144] |
1.91[145] |
22 |
PPP2CB |
Serine/threonine-protein phosphatase
2A catalytic subunit beta isoform |
-0.65[146] |
-0.90[147] |
-0.83[148] |
-0.52[149] |
-0.37[150] |
-0.91[151] |
23 |
ENO3 |
Beta-enolase |
[152] |
-2.52[153] |
-2.30[154] |
-4.38[155] |
-2.21[156] |
-5.40[157] |
-0.76[158] |
24 |
PFKL |
ATP-dependent 6-phosphofructokinase, liver type |
[159] |
0.83[160] |
0.98[161] |
0.82[162] |
0.51[163] |
0.33[164] |
0.78[165] |
25 |
SLC25A10 |
Mitochondrial dicarboxylate carrier |
[166] |
0.35[167] |
0.25[168] |
-1.46[169] |
-2.04[170] |
-1.37[171] |
-0.43[172] |
26 |
SLC25A13 |
Calcium-binding mitochondrial carrier protein Aralar2 |
[173] |
-0.49[174] |
0.08[175] |
0.32[176] |
-0.54[177] |
-1.53[178] |
1.51[179] |
27 |
GCKR |
Glucokinase regulatory protein |
[180] |
-4.52[181] |
-1.59[182] |
-4.97[183] |
-8.59[184] |
-5.82[185] |
1.02[186] |
28 |
ALDOC |
Fructose-bisphosphate aldolase C |
[187] |
-1.80[188] |
-0.18[189] |
0.57[190] |
-1.04[191] |
-2.47[192] |
0.41[193] |
29 |
SLC25A11 |
Mitochondrial 2-oxoglutarate/malate carrier protein |
[194] |
-0.53[195] |
-0.40[196] |
-0.35[197] |
-0.47[198] |
-0.01[199] |
0.25[200] |
30 |
PRKACA |
cAMP-dependent protein kinase catalytic subunit alpha |
[201] |
-0.42[202] |
-0.50[203] |
-0.51[204] |
-0.53[205] |
0.31[206] |
-0.71[207] |
31 |
PPP2R1B |
Serine/threonine-protein phosphatase
2A 65 kDa regulatory subunit A beta isoform |
0.19[208] |
-0.23[209] |
0.17[210] |
0.21[211] |
0.24[212] |
3.00[213] |
32 |
RAE1 |
mRNA export factor |
[214] |
0.32[215] |
0.13[216] |
-1.01[217] |
0.51[218] |
0.07[219] |
-0.94[220] |
33 |
NUP88 |
Nuclear pore complex protein Nup88 |
[221] |
-0.31[222] |
0.31[223] |
0.40[224] |
-0.39[225] |
0.36[226] |
1.19[227] |
34 |
SEH1L |
Nucleoporin SEH1 |
[228] |
-0.03[229] |
0.55[230] |
1.00[231] |
0.51[232] |
-0.02[233] |
0.25[234] |
35 |
PFKP |
ATP-dependent 6-phosphofructokinase, platelet type |
[235] |
-0.45[236] |
-2.11[237] |
-6.78[238] |
3.48[239] |
2.39[240] |
-2.88[241] |
36 |
ADPGK |
ADP-dependent glucokinase |
[242] |
0.51[243] |
0.35[244] |
0.49[245] |
0.01[246] |
1.01[247] |
-0.32[248] |
37 |
NUP35 |
Nucleoporin NUP53 |
[249] |
-1.34[250] |
-0.66[251] |
-0.70[252] |
-1.16[253] |
-1.12[254] |
-1.15[255] |
38 |
GNPDA1 |
Glucosamine-6-phosphate isomerase 1 |
[256] |
0.67[257] |
-0.17[258] |
-0.24[259] |
0.84[260] |
1.06[261] |
-0.87[262] |
39 |
NUP62 |
Nuclear pore glycoprotein p62 |
[263] |
0.91[264] |
0.62[265] |
1.66[266] |
1.14[267] |
1.48[268] |
0.49[269] |
40 |
PPP2R5D |
Serine/threonine-protein phosphatase
2A 56 kDa regulatory subunit delta isoform |
0.99[270] |
0.85[271] |
0.39[272] |
1.22[273] |
1.36[274] |
-0.20[275] |
41 |
PKLR |
Pyruvate kinase PKLR |
[276] |
-2.12[277] |
-0.15[278] |
-1.89[279] |
-10.24[280] |
-9.89[281] |
1.03[282] |
42 |
NUP85 |
Nuclear pore complex protein Nup85 |
[283] |
0.49[284] |
0.94[285] |
1.17[286] |
0.51[287] |
0.97[288] |
0.29[289] |
43 |
AAAS |
Aladin |
[290] |
0.01[291] |
0.42[292] |
0.00[293] |
0.15[294] |
0.44[295] |
-0.11[296] |
44 |
NUP50 |
Nuclear pore complex protein Nup50 |
[297] |
0.51[298] |
1.29[299] |
1.68[300] |
0.92[301] |
1.66[302] |
1.63[303] |
45 |
RANBP2 |
E3 SUMO-protein ligase RanBP2 |
[304] |
0.22[305] |
2.00[306] |
1.73[307] |
1.47[308] |
1.88[309] |
3.02[310] |
46 |
NUP93 |
Nuclear pore complex protein Nup93 |
[311] |
1.42[312] |
1.04[313] |
1.00[314] |
0.87[315] |
1.43[316] |
-0.43[317] |
47 |
NUP98 |
Nuclear pore complex protein Nup98-Nup96 |
[318] |
1.91[319] |
1.70[320] |
1.95[321] |
2.16[322] |
1.97[323] |
1.93[324] |
48 |
NUP54 |
Nucleoporin p54 |
[325] |
-0.15[326] |
0.59[327] |
0.57[328] |
0.27[329] |
0.99[330] |
0.08[331] |
49 |
NUP107 |
Nuclear pore complex protein Nup107 |
[332] |
0.24[333] |
1.45[334] |
1.43[335] |
1.23[336] |
1.40[337] |
0.07[338] |
50 |
BPGM |
Bisphosphoglycerate mutase |
[339] |
-2.25[340] |
-2.03[341] |
-0.83[342] |
-0.40[343] |
-0.23[344] |
-0.89[345] |
51 |
NUP37 |
Nucleoporin Nup37 |
[346] |
0.40[347] |
0.78[348] |
0.86[349] |
0.38[350] |
0.63[351] |
-1.35[352] |
52 |
TPR |
Nucleoprotein TPR |
[353] |
0.38[354] |
2.34[355] |
2.63[356] |
2.48[357] |
2.96[358] |
2.66[359] |
53 |
G6PC3 |
Glucose-6-phosphatase 3 |
[360] |
1.41[361] |
1.11[362] |
-0.51[363] |
0.99[364] |
1.16[365] |
-1.21[366] |
54 |
PFKFB3 |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 |
[367] |
2.36[368] |
-0.15[369] |
0.00[370] |
3.65[371] |
0.93[372] |
-0.26[373] |
55 |
NUP160 |
Nuclear pore complex protein Nup160 |
[374] |
1.60[375] |
1.84[376] |
2.43[377] |
1.11[378] |
1.66[379] |
1.54[380] |
56 |
PFKFB1 |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 |
[381] |
-3.04[382] |
-2.20[383] |
-7.33[384] |
-7.33[385] |
-7.67[386] |
0.44[387] |
57 |
POM121 |
Nuclear envelope pore membrane protein POM 121 |
[388] |
1.19[389] |
1.64[390] |
1.46[391] |
1.48[392] |
1.18[393] |
1.37[394] |
58 |
NUP133 |
Nuclear pore complex protein Nup133 |
[395] |
0.93[396] |
1.37[397] |
2.32[398] |
2.14[399] |
1.74[400] |
1.12[401] |
59 |
NUP153 |
Nuclear pore complex protein Nup153 |
[402] |
2.14[403] |
2.43[404] |
2.06[405] |
3.19[406] |
2.60[407] |
2.01[408] |
60 |
NUP43 |
Nucleoporin Nup43 |
[409] |
1.66[410] |
1.93[411] |
1.67[412] |
2.02[413] |
2.00[414] |
0.38[415] |
61 |
NUP205 |
Nuclear pore complex protein Nup205 |
[416] |
1.93[417] |
1.94[418] |
3.10[419] |
2.71[420] |
3.14[421] |
1.58[422] |
62 |
POM121C |
Nuclear envelope pore membrane protein POM 121C |
[423] |
1.03[424] |
0.39[425] |
0.04[426] |
1.34[427] |
1.01[428] |
0.50[429] |
63 |
PGP |
Glycerol-3-phosphate phosphatase |
[430] |
0.87[431] |
1.41[432] |
1.36[433] |
0.23[434] |
1.16[435] |
0.16[436] |
64 |
NUP214 |
Nuclear pore complex protein Nup214 |
[437] |
1.77[438] |
1.17[439] |
2.29[440] |
2.12[441] |
2.30[442] |
1.83[443] |
65 |
PRKACB |
cAMP-dependent protein kinase catalytic subunit beta |
[444] |
-1.09[445] |
-0.22[446] |
1.05[447] |
2.17[448] |
1.28[449] |
1.78[450] |
66 |
NUP188 |
Nucleoporin NUP188 homolog |
[451] |
3.01[452] |
2.48[453] |
3.11[454] |
2.45[455] |
3.88[456] |
1.90[457] |
67 |
NUP210 |
Nuclear pore membrane glycoprotein 210 |
[458] |
3.45[459] |
3.35[460] |
4.44[461] |
2.04[462] |
0.68[463] |
3.07[464] |
68 |
NUP155 |
Nuclear pore complex protein Nup155 |
[465] |
1.86[466] |
1.56[467] |
2.53[468] |
2.41[469] |
3.53[470] |
1.81[471] |
69 |
HK1 |
Hexokinase-1 |
[472] |
0.66[473] |
-4.14[474] |
-5.42[475] |
4.47[476] |
4.77[477] |
0.99[478] |
70 |
ENO2 |
Gamma-enolase |
[479] |
4.35[480] |
3.20[481] |
0.99[482] |
2.59[483] |
3.81[484] |
-1.65[485] |
71 |
PFKM |
ATP-dependent 6-phosphofructokinase, muscle type |
[486] |
-1.83[487] |
-1.13[488] |
3.86[489] |
3.28[490] |
3.93[491] |
0.98[492] |
72 |
SLC37A1 |
Glucose-6-phosphate exchanger SLC37A1 |
[493] |
-2.70[494] |
-7.27[495] |
-0.81[496] |
0.49[497] |
-2.13[498] |
0.27[499] |
73 |
GNPDA2 |
Glucosamine-6-phosphate isomerase 2 |
[500] |
-0.12[501] |
0.60[502] |
0.37[503] |
1.70[504] |
2.26[505] |
0.22[506] |
74 |
PFKFB2 |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 |
[507] |
1.44[508] |
2.03[509] |
1.32[510] |
2.26[511] |
1.10[512] |
1.95[513] |
75 |
PGM2L1 |
Glucose 1,6-bisphosphate synthase |
[514] |
1.08[515] |
-0.22[516] |
0.58[517] |
3.34[518] |
1.34[519] |
0.88[520] |
76 |
SLC37A2 |
Glucose-6-phosphate exchanger SLC37A2 |
[521] |
1.55[522] |
2.15[523] |
1.52[524] |
0.17[525] |
1.39[526] |
1.97[527] |
77 |
SLC25A12 |
Calcium-binding mitochondrial carrier protein Aralar1 |
[528] |
1.93[529] |
2.20[530] |
-0.48[531] |
3.11[532] |
3.61[533] |
0.34[534] |
78 |
HK2 |
Hexokinase-2 |
[535] |
5.63[536] |
6.07[537] |
5.13[538] |
3.80[539] |
4.83[540] |
0.61[541] |
79 |
GCK |
Glucokinase |
[542] |
-8.21[543] |
-6.11[544] |
-9.32[545] |
-6.99[546] |
-4.79[547] |
2.00[548] |
80 |
HK3 |
Hexokinase-3 |
[549] |
-8.10[550] |
-7.93[551] |
-8.86[552] |
-5.57[553] |
-8.51[554] |
3.04[555] |
81 |
PFKFB4 |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 |
[556] |
5.00[557] |
5.14[558] |
5.60[559] |
2.88[560] |
2.68[561] |
0.41[562] |
82 |
PGAM2 |
Phosphoglycerate mutase 2 |
[563] |
-2.35[564] |
-0.15[565] |
0.12[566] |
-0.68[567] |
-1.40[568] |
0.48[569] |
83 |
FBP2 |
Fructose-1,6-bisphosphatase isozyme 2 |
[570] |
-1.67[571] |
-0.70[572] |
0.43[573] |
-3.21[574] |
-6.27[575] |
-2.49[576] |
84 |
GAPDHS |
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific |
[577] |
2.68[578] |
3.46[579] |
3.69[580] |
2.60[581] |
3.36[582] |
2.98[583] |
85 |
NUP58 |
Nucleoporin p58/p45 |
[584] |
[585] |
[586] |
[587] |
[588] |
[589] |
[590] |
86 |
PGK2 |
Phosphoglycerate kinase 2 |
[591] |
[592] |
[593] |
[594] |
[595] |
[596] |
[597] |
87 |
PKM |
Pyruvate kinase PKM |
[598] |
[599] |
[600] |
[601] |
[602] |
[603] |
[604] |
88 |
G6PC1 |
|
[605] |
[606] |
[607] |
[608] |
[609] |
[610] |
[611] |
89 |
PRKACG |
cAMP-dependent protein kinase catalytic subunit gamma |
[612] |
[613] |
[614] |
[615] |
[616] |
[617] |
[618] |
90 |
G6PC2 |
Glucose-6-phosphatase 2 |
[619] |
[620] |
[621] |
[622] |
[623] |
[624] |
[625] |
91 |
NDC1 |
Nucleoporin NDC1 |
[626] |
[627] |
[628] |
[629] |
[630] |
[631] |
[632] |
92 |
NUP42 |
|
[633] |
[634] |
[635] |
[636] |
[637] |
[638] |
[639] |
|
|
|
|
|
|
|
|
|
|