REACTOME_GLI_PROTEINS_BIND_PROMOTERS_OF_HH_RESPONSIVE_GENES_TO_PROMOTE_TRANSCRIPTION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 PTCH1 Protein patched homolog 1 [1] 0.45[2] 0.22[3] 0.71[4] -2.03[5] -1.69[6] -0.98[7]
2 GLI1 Zinc finger protein GLI1 [8] -3.83[9] -4.46[10] -2.09[11] -6.44[12] -2.84[13] -2.86[14]
3 PTCH2 Protein patched homolog 2 [15] 1.04[16] 1.89[17] -2.57[18] -4.84[19] -2.66[20] -1.90[21]
4 GLI2 Zinc finger protein GLI2 [22] -1.55[23] -5.56[24] -4.69[25] 3.11[26] 3.29[27] -0.94[28]
5 GLI3 Transcriptional activator GLI3 [29] -3.42[30] [31] -3.80[32] 3.58[33] 2.95[34] 0.33[35]
6 BOC Brother of CDO [36] -0.67[37] [38] -3.94[39] 2.41[40] 1.19[41] 0.73[42]
7 HHIP Hedgehog-interacting protein [43] [44] [45] [46] [47] [48] [49]
[1]
ref_hepatocyte PTCH1
Mean 0.253
Standard deviation 0.18
Values 0.17 0.14 0.51 0.078 0.37
[2]
HepG2 PTCH1
Mean 3.48
Standard deviation 2.7
Values 5.4 1.6
[3]
HepG2.C3A PTCH1
Mean 3.66
Standard deviation 0.94
Values 4.3 3
[4]
HuH.7 PTCH1
Mean 9.01
Standard deviation 1
Values 10 9 7.9
[5]
SNU475 PTCH1
Mean 4.67
Standard deviation 0.47
Values 4.3 5
[6]
THLE PTCH1
Mean 3.31
Standard deviation 0.69
Values 2.8 3.8
[7]
liver PTCH1
Mean 2.58
Standard deviation 0.39
Values 2.9 2 2.8 2.6
[8]
ref_hepatocyte GLI1
Mean 0.113
Standard deviation 0.22
Values 0 0 0.5 0.043 0.024
[9]
HepG2 GLI1
Mean 0.0802
Standard deviation 0.041
Values 0.11 0.051
[10]
HepG2.C3A GLI1
Mean 0.0642
Standard deviation 0.06
Values 0.11 0.021
[11]
HuH.7 GLI1
Mean 0.579
Standard deviation 0.11
Values 0.63 0.65 0.45
[12]
SNU475 GLI1
Mean 0.0979
Standard deviation 0.034
Values 0.074 0.12
[13]
THLE GLI1
Mean 0.667
Standard deviation 0.23
Values 0.83 0.51
[14]
liver GLI1
Mean 0.315
Standard deviation 0.33
Values 0.75 0.071 0.051 0.38
[15]
ref_hepatocyte PTCH2
Mean 0.0404
Standard deviation 0.056
Values 0 0.13 0 0.043 0.024
[16]
HepG2 PTCH2
Mean 0.839
Standard deviation 0.48
Values 1.2 0.5
[17]
HepG2.C3A PTCH2
Mean 1.86
Standard deviation 1
Values 2.6 1.1
[18]
HuH.7 PTCH2
Mean 0.148
Standard deviation 0.03
Values 0.18 0.14 0.12
[19]
SNU475 PTCH2
Mean 0.106
Standard deviation 0.065
Values 0.06 0.15
[20]
THLE PTCH2
Mean 0.27
Standard deviation 0.1
Values 0.34 0.2
[21]
liver PTCH2
Mean 0.218
Standard deviation 0.1
Values 0.33 0.086 0.23 0.23
[22]
ref_hepatocyte GLI2
Mean 0.0185
Standard deviation 0.037
Values 0 0 0.084 0 0.0081
[23]
HepG2 GLI2
Mean 0.0637
Standard deviation 0.023
Values 0.08 0.047
[24]
HepG2.C3A GLI2
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[25]
HuH.7 GLI2
Mean 0.0156
Standard deviation 0.02
Values 0.0082 0.039 0
[26]
SNU475 GLI2
Mean 12
Standard deviation 1.6
Values 13 11
[27]
THLE GLI2
Mean 7.63
Standard deviation 1.7
Values 6.4 8.8
[28]
liver GLI2
Mean 0.194
Standard deviation 0.054
Values 0.14 0.23 0.15 0.25
[29]
ref_hepatocyte GLI3
Mean 0.0152
Standard deviation 0.021
Values 0 0 0.043 0 0.033
[30]
HepG2 GLI3
Mean 0.0143
Standard deviation 0.02
Values 0.029 0
[31]
HepG2.C3A GLI3
Mean 0
Standard deviation 0
Values 0 0
[32]
HuH.7 GLI3
Mean 0.0238
Standard deviation 0.021
Values 0.033 0.039 0
[33]
SNU475 GLI3
Mean 13.7
Standard deviation 1.2
Values 14 13
[34]
THLE GLI3
Mean 4.94
Standard deviation 1.2
Values 4.1 5.8
[35]
liver GLI3
Mean 0.384
Standard deviation 0.18
Values 0.59 0.37 0.15 0.42
[36]
ref_hepatocyte BOC
Mean 0.00813
Standard deviation 0.018
Values 0 0 0 0 0.041
[37]
HepG2 BOC
Mean 0.0516
Standard deviation 0.049
Values 0.086 0.017
[38]
HepG2.C3A BOC
Mean 0
Standard deviation 0
Values 0 0
[39]
HuH.7 BOC
Mean 0.0115
Standard deviation 0.015
Values 0 0.0064 0.028
[40]
SNU475 BOC
Mean 3.24
Standard deviation 0.38
Values 3.5 3
[41]
THLE BOC
Mean 0.781
Standard deviation 0.13
Values 0.88 0.69
[42]
liver BOC
Mean 0.271
Standard deviation 0.4
Values 0.024 0.071 0.13 0.86
[43]
ref_hepatocyte HHIP
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[44]
HepG2 HHIP
Mean 0.00788
Standard deviation 0.0051
Values 0.011 0.0043
[45]
HepG2.C3A HHIP
Mean 0
Standard deviation 0
Values 0 0
[46]
HuH.7 HHIP
Mean 0.00586
Standard deviation 0.0051
Values 0.0082 0 0.0094
[47]
SNU475 HHIP
Mean 0.035
Standard deviation 0.036
Values 0.0093 0.061
[48]
THLE HHIP
Mean 1.37
Standard deviation 0.85
Values 0.77 2
[49]
liver HHIP
Mean 5.1
Standard deviation 1.4
Values 3.8 6.3 6.4 4