REACTOME_GAP_JUNCTION_DEGRADATION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 ACTB Actin, cytoplasmic 1 [1] -0.72[2] -0.55[3] -0.28[4] -0.16[5] -0.52[6] -0.04[7]
2 ACTG1 Actin, cytoplasmic 2 [8] 0.56[9] 0.09[10] -0.17[11] -0.36[12] 0.07[13] -0.79[14]
3 CLTA Clathrin light chain A [15] -1.20[16] -0.53[17] -0.78[18] -1.63[19] -1.23[20] -2.12[21]
4 CLTB Clathrin light chain B [22] 0.11[23] -1.04[24] -1.60[25] -1.82[26] -1.42[27] -1.15[28]
5 AP2M1 AP-2 complex subunit mu [29] 0.89[30] 1.55[31] 0.68[32] 1.81[33] 2.35[34] 0.98[35]
6 CLTC Clathrin heavy chain 1 [36] 2.29[37] 3.24[38] 3.05[39] 2.51[40] 2.68[41] 3.60[42]
7 DNM2 Dynamin-2 [43] 2.68[44] 2.47[45] 2.38[46] 1.78[47] 2.08[48] 1.91[49]
8 MYO6 Unconventional myosin-VI [50] 1.16[51] 3.15[52] 3.05[53] 1.96[54] 1.79[55] 3.42[56]
9 DAB2 Disabled homolog 2 [57] 1.96[58] 0.93[59] 3.47[60] 5.13[61] 3.01[62] 3.39[63]
10 GJA1 Gap junction alpha-1 protein [64] -2.18[65] -1.03[66] 5.83[67] 5.79[68] 5.90[69] 0.80[70]
11 CLTCL1 Clathrin heavy chain 2 [71] 2.75[72] 3.16[73] 2.65[74] 2.74[75] 2.21[76] 2.89[77]
12 DNM1 Dynamin-1 [78] 2.91[79] 1.94[80] 3.28[81] 6.43[82] 5.95[83] 3.08[84]
[1]
ref_hepatocyte ACTB
Mean 1.3e+03
Standard deviation 6.4e+02
Values 1.6e+03 1.8e+03 1.9e+03 6.8e+02 5.5e+02
[2]
HepG2 ACTB
Mean 1.1e+03
Standard deviation 45
Values 1.1e+03 1.1e+03
[3]
HepG2.C3A ACTB
Mean 609
Standard deviation 6.4
Values 6e+02 6.1e+02
[4]
HuH.7 ACTB
Mean 903
Standard deviation 3.5e+02
Values 1.1e+03 5e+02 1.1e+03
[5]
SNU475 ACTB
Mean 1.2e+03
Standard deviation 5e+02
Values 1.6e+03 8.5e+02
[6]
THLE ACTB
Mean 1.03e+03
Standard deviation 3.2e+02
Values 8.1e+02 1.3e+03
[7]
liver ACTB
Mean 816
Standard deviation 6.8e+02
Values 1.2e+03 2.3e+02 1.6e+03 2.7e+02
[8]
ref_hepatocyte ACTG1
Mean 733
Standard deviation 4e+02
Values 1.1e+03 1e+03 9.5e+02 3.5e+02 2.4e+02
[9]
HepG2 ACTG1
Mean 1.5e+03
Standard deviation 1.8e+02
Values 1.6e+03 1.4e+03
[10]
HepG2.C3A ACTG1
Mean 534
Standard deviation 1.5e+02
Values 6.4e+02 4.3e+02
[11]
HuH.7 ACTG1
Mean 549
Standard deviation 1.6e+02
Values 6.7e+02 3.7e+02 6e+02
[12]
SNU475 ACTG1
Mean 591
Standard deviation 2.2e+02
Values 7.5e+02 4.3e+02
[13]
THLE ACTG1
Mean 872
Standard deviation 1.9e+02
Values 7.3e+02 1e+03
[14]
liver ACTG1
Mean 273
Standard deviation 78
Values 3.2e+02 1.9e+02 3.6e+02 2.2e+02
[15]
ref_hepatocyte CLTA
Mean 139
Standard deviation 77
Values 2e+02 2.3e+02 1.4e+02 74 53
[16]
HepG2 CLTA
Mean 83.5
Standard deviation 9.9
Values 91 77
[17]
HepG2.C3A CLTA
Mean 65.7
Standard deviation 0.97
Values 66 65
[18]
HuH.7 CLTA
Mean 68.1
Standard deviation 8
Values 60 68 76
[19]
SNU475 CLTA
Mean 46.3
Standard deviation 2.6
Values 48 45
[20]
THLE CLTA
Mean 67.1
Standard deviation 17
Values 55 79
[21]
liver CLTA
Mean 20.5
Standard deviation 13
Values 32 10 31 8.4
[22]
ref_hepatocyte CLTB
Mean 49.9
Standard deviation 29
Values 19 72 89 39 30
[23]
HepG2 CLTB
Mean 74.4
Standard deviation 33
Values 98 51
[24]
HepG2.C3A CLTB
Mean 16.5
Standard deviation 2.8
Values 15 18
[25]
HuH.7 CLTB
Mean 13.9
Standard deviation 2.8
Values 14 11 17
[26]
SNU475 CLTB
Mean 14.6
Standard deviation 1.2
Values 14 15
[27]
THLE CLTB
Mean 21
Standard deviation 2.5
Values 19 23
[28]
liver CLTB
Mean 14.4
Standard deviation 8.2
Values 24 8.6 19 6.4
[29]
ref_hepatocyte AP2M1
Mean 41.6
Standard deviation 13
Values 28 39 35 63 44
[30]
HepG2 AP2M1
Mean 107
Standard deviation 14
Values 97 1.2e+02
[31]
HepG2.C3A AP2M1
Mean 83
Standard deviation 17
Values 71 95
[32]
HuH.7 AP2M1
Mean 56.4
Standard deviation 14
Values 67 40 62
[33]
SNU475 AP2M1
Mean 150
Standard deviation 32
Values 1.7e+02 1.3e+02
[34]
THLE AP2M1
Mean 241
Standard deviation 26
Values 2.2e+02 2.6e+02
[35]
liver AP2M1
Mean 52.8
Standard deviation 26
Values 55 35 89 32
[36]
ref_hepatocyte CLTC
Mean 30
Standard deviation 17
Values 53 42 13 19 24
[37]
HepG2 CLTC
Mean 203
Standard deviation 93
Values 1.4e+02 2.7e+02
[38]
HepG2.C3A CLTC
Mean 193
Standard deviation 28
Values 1.7e+02 2.1e+02
[39]
HuH.7 CLTC
Mean 209
Standard deviation 37
Values 2.5e+02 2.1e+02 1.7e+02
[40]
SNU475 CLTC
Mean 176
Standard deviation 18
Values 1.9e+02 1.6e+02
[41]
THLE CLTC
Mean 218
Standard deviation 18
Values 2.1e+02 2.3e+02
[42]
liver CLTC
Mean 234
Standard deviation 1.1e+02
Values 1.2e+02 3.7e+02 1.8e+02 2.7e+02
[43]
ref_hepatocyte DNM2
Mean 12.4
Standard deviation 3.9
Values 7.7 11 17 16 11
[44]
HepG2 DNM2
Mean 111
Standard deviation 21
Values 1.3e+02 96
[45]
HepG2.C3A DNM2
Mean 47.1
Standard deviation 1.8
Values 48 46
[46]
HuH.7 DNM2
Mean 54.4
Standard deviation 4.5
Values 59 53 51
[47]
SNU475 DNM2
Mean 44.3
Standard deviation 3.3
Values 47 42
[48]
THLE DNM2
Mean 59.7
Standard deviation 7.8
Values 54 65
[49]
liver DNM2
Mean 30.1
Standard deviation 7.9
Values 23 30 26 41
[50]
ref_hepatocyte MYO6
Mean 4.14
Standard deviation 2.1
Values 5.9 6.2 4.6 1.5 2.5
[51]
HepG2 MYO6
Mean 12.8
Standard deviation 1.3
Values 12 14
[52]
HepG2.C3A MYO6
Mean 25
Standard deviation 2.5
Values 27 23
[53]
HuH.7 MYO6
Mean 28.9
Standard deviation 4.2
Values 29 33 24
[54]
SNU475 MYO6
Mean 16.6
Standard deviation 3.3
Values 19 14
[55]
THLE MYO6
Mean 16.2
Standard deviation 2.4
Values 18 15
[56]
liver MYO6
Mean 28.4
Standard deviation 9.3
Values 41 26 29 18
[57]
ref_hepatocyte DAB2
Mean 2.2
Standard deviation 1.3
Values 1 1.9 4.5 2.2 1.4
[58]
HepG2 DAB2
Mean 11.8
Standard deviation 10
Values 4.4 19
[59]
HepG2.C3A DAB2
Mean 2.86
Standard deviation 1.2
Values 2 3.7
[60]
HuH.7 DAB2
Mean 20.6
Standard deviation 5.2
Values 19 26 16
[61]
SNU475 DAB2
Mean 79.5
Standard deviation 40
Values 1.1e+02 51
[62]
THLE DAB2
Mean 20
Standard deviation 0.11
Values 20 20
[63]
liver DAB2
Mean 14.8
Standard deviation 7.4
Values 14 13 25 7.4
[64]
ref_hepatocyte GJA1
Mean 0.931
Standard deviation 1.5
Values 0 0.036 3.6 0.052 0.98
[65]
HepG2 GJA1
Mean 0.285
Standard deviation 0.0024
Values 0.29 0.28
[66]
HepG2.C3A GJA1
Mean 0.31
Standard deviation 0.029
Values 0.33 0.29
[67]
HuH.7 GJA1
Mean 44.5
Standard deviation 9.8
Values 48 33 52
[68]
SNU475 GJA1
Mean 53.2
Standard deviation 4.6
Values 56 50
[69]
THLE GJA1
Mean 63.1
Standard deviation 13
Values 54 72
[70]
liver GJA1
Mean 1.04
Standard deviation 0.55
Values 0.54 1.6 0.62 1.4
[71]
ref_hepatocyte CLTCL1
Mean 0.765
Standard deviation 0.32
Values 1.1 0.77 1.1 0.49 0.4
[72]
HepG2 CLTCL1
Mean 7.14
Standard deviation 1.5
Values 6.1 8.2
[73]
HepG2.C3A CLTCL1
Mean 4.66
Standard deviation 0.92
Values 5.3 4
[74]
HuH.7 CLTCL1
Mean 4.04
Standard deviation 1.1
Values 5.3 3.2 3.6
[75]
SNU475 CLTCL1
Mean 5.26
Standard deviation 1.2
Values 6.1 4.4
[76]
THLE CLTCL1
Mean 4
Standard deviation 0.31
Values 3.8 4.2
[77]
liver CLTCL1
Mean 3.65
Standard deviation 1.7
Values 2.1 6 2.9 3.6
[78]
ref_hepatocyte DNM1
Mean 0.16
Standard deviation 0.16
Values 0 0.15 0 0.35 0.3
[79]
HepG2 DNM1
Mean 1.67
Standard deviation 1.2
Values 2.5 0.85
[80]
HepG2.C3A DNM1
Mean 0.418
Standard deviation 0.29
Values 0.62 0.21
[81]
HuH.7 DNM1
Mean 1.31
Standard deviation 0.22
Values 1.3 1.5 1.1
[82]
SNU475 DNM1
Mean 14.2
Standard deviation 4.2
Values 17 11
[83]
THLE DNM1
Mean 11.2
Standard deviation 0.44
Values 11 11
[84]
liver DNM1
Mean 0.869
Standard deviation 0.9
Values 0.73 0.36 0.21 2.2