REACTOME_GABA_B_RECEPTOR_ACTIVATION | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | GNG5 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 | -1.07[1] | -0.73[2] | -1.73[3] | -2.15[4] | -2.58[5] | -1.33[6] | |
2 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | [7] | 1.15[8] | 1.33[9] | 0.71[10] | 0.94[11] | 0.57[12] | -0.98[13] |
3 | GNB2 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 | [14] | -0.46[15] | -0.56[16] | -0.36[17] | -0.70[18] | -0.82[19] | -1.35[20] |
4 | GNG10 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 | -4.56[21] | -4.12[22] | -4.56[23] | -4.15[24] | -3.51[25] | -4.09[26] | |
5 | GNAI2 | Guanine nucleotide-binding protein G(i) subunit alpha-2 | [27] | 0.20[28] | -0.70[29] | -0.67[30] | -0.51[31] | 0.39[32] | 0.06[33] |
6 | GNG12 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 | -4.61[34] | -7.38[35] | 0.43[36] | 1.54[37] | 1.47[38] | 0.74[39] | |
7 | GNAI3 | Guanine nucleotide-binding protein G(k) subunit alpha | [40] | 0.26[41] | 0.97[42] | 0.93[43] | 0.77[44] | 0.22[45] | 0.49[46] |
8 | GNAI1 | Guanine nucleotide-binding protein G(i) subunit alpha-1 | [47] | -1.51[48] | -2.29[49] | -0.29[50] | 0.88[51] | 0.08[52] | 1.09[53] |
9 | GNB5 | Guanine nucleotide-binding protein subunit beta-5 | [54] | 0.24[55] | 0.44[56] | 1.32[57] | 0.45[58] | 0.40[59] | 1.14[60] |
10 | ADCY9 | Adenylate cyclase type 9 | [61] | 2.76[62] | 2.11[63] | 2.39[64] | 0.62[65] | -0.01[66] | 2.67[67] |
11 | ADCY6 | Adenylate cyclase type 6 | [68] | 2.19[69] | 2.81[70] | 2.63[71] | 2.17[72] | 2.66[73] | 2.89[74] |
12 | GNG11 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 | -8.04[75] | -7.88[76] | -7.33[77] | 1.93[78] | 3.07[79] | 2.49[80] | |
13 | GNG7 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 | 1.69[81] | 1.50[82] | 2.17[83] | -2.57[84] | -2.12[85] | 0.28[86] | |
14 | ADCY1 | Adenylate cyclase type 1 | [87] | -0.70[88] | -2.41[89] | -2.75[90] | -2.45[91] | -2.64[92] | 5.25[93] |
15 | GNG4 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 | 3.61[94] | 1.53[95] | 5.19[96] | 0.92[97] | -1.37[98] | -2.29[99] | |
16 | KCNJ5 | G protein-activated inward rectifier potassium channel 4 | [100] | -2.39[101] | -0.93[102] | -1.57[103] | -2.56[104] | -2.97[105] | -1.82[106] |
17 | ADCY7 | Adenylate cyclase type 7 | [107] | 3.65[108] | 3.43[109] | 2.25[110] | 2.97[111] | 2.27[112] | 3.18[113] |
18 | GNB4 | Guanine nucleotide-binding protein subunit beta-4 | [114] | -0.23[115] | 0.42[116] | 1.28[117] | 2.34[118] | 4.91[119] | 4.35[120] |
19 | GNG2 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | -6.14[121] | -6.86[122] | [123] | 2.78[124] | 2.08[125] | 3.04[126] | |
20 | GNAL | Guanine nucleotide-binding protein G(olf) subunit alpha | [127] | 1.98[128] | 2.94[129] | 3.08[130] | 1.76[131] | 1.56[132] | 2.80[133] |
21 | GNGT2 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 | [134] | [135] | [136] | -2.41[137] | -7.25[138] | 0.36[139] | |
22 | KCNJ4 | Inward rectifier potassium channel 4 | [140] | 0.39[141] | 0.62[142] | 1.96[143] | -5.34[144] | -2.33[145] | -0.89[146] |
23 | GNG3 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 | -0.72[147] | 1.28[148] | -1.09[149] | -1.04[150] | -1.53[151] | 0.17[152] | |
24 | ADCY3 | Adenylate cyclase type 3 | [153] | 1.60[154] | 0.51[155] | 3.70[156] | 4.40[157] | 5.76[158] | 3.77[159] |
25 | ADCY2 | Adenylate cyclase type 2 | [160] | -5.24[161] | -3.15[162] | -4.55[163] | -3.07[164] | -4.36[165] | -3.86[166] |
26 | GNB3 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 | [167] | 1.73[168] | 4.14[169] | 3.30[170] | 0.67[171] | 3.21[172] | -1.42[173] |
27 | KCNJ6 | G protein-activated inward rectifier potassium channel 2 | [174] | [175] | [176] | [177] | 0.46[178] | -5.62[179] | -2.20[180] |
28 | KCNJ15 | ATP-sensitive inward rectifier potassium channel 15 | [181] | -2.29[182] | [183] | [184] | 2.32[185] | 2.84[186] | 5.41[187] |
29 | GABBR1 | Gamma-aminobutyric acid type B receptor subunit 1 | [188] | 2.81[189] | 1.33[190] | 0.43[191] | 6.43[192] | 6.56[193] | 4.30[194] |
30 | KCNJ3 | G protein-activated inward rectifier potassium channel 1 | [195] | -1.96[196] | 0.98[197] | 4.85[198] | -0.78[199] | -2.33[200] | 4.99[201] |
31 | ADCY5 | Adenylate cyclase type 5 | [202] | 0.29[203] | 1.45[204] | 2.34[205] | 0.31[206] | 1.26[207] | 6.63[208] |
32 | KCNJ2 | Inward rectifier potassium channel 2 | [209] | -2.20[210] | [211] | [212] | 2.94[213] | 2.92[214] | 6.13[215] |
33 | KCNJ10 | ATP-sensitive inward rectifier potassium channel 10 | [216] | 8.32[217] | 1.59[218] | 0.46[219] | 2.10[220] | 0.38[221] | 4.89[222] |
34 | KCNJ16 | Inward rectifier potassium channel 16 | [223] | [224] | [225] | -1.44[226] | 2.52[227] | 0.38[228] | 5.96[229] |
35 | ADCY4 | Adenylate cyclase type 4 | [230] | 0.23[231] | -0.68[232] | 1.82[233] | [234] | [235] | 8.62[236] |
36 | GABBR2 | Gamma-aminobutyric acid type B receptor subunit 2 | [237] | 3.48[238] | 1.64[239] | 2.63[240] | 1.80[241] | 5.94[242] | 4.69[243] |
37 | KCNJ12 | ATP-sensitive inward rectifier potassium channel 12 | [244] | [245] | [246] | -0.01[247] | 7.44[248] | 6.61[249] | 5.68[250] |
38 | KCNJ9 | G protein-activated inward rectifier potassium channel 3 | [251] | [252] | [253] | [254] | [255] | [256] | [257] |
39 | ADCY8 | Adenylate cyclase type 8 | [258] | [259] | [260] | [261] | [262] | [263] | [264] |
40 | GNG13 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 | [265] | [266] | [267] | [268] | [269] | [270] | |
41 | GNGT1 | Guanine nucleotide-binding protein G(T) subunit gamma-T1 | [271] | [272] | [273] | [274] | [275] | [276] | [277] |
42 | GNG8 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 | [278] | [279] | [280] | [281] | [282] | [283] | |
43 | GNAT3 | Guanine nucleotide-binding protein G(t) subunit alpha-3 | [284] | [285] | [286] | [287] | [288] | [289] | [290] |