REACTOME_FREE_FATTY_ACIDS_REGULATE_INSULIN_SECRETION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 ACSL3 Long-chain-fatty-acid--CoA ligase 3 [1] -1.12[2] -0.57[3] -1.39[4] -0.74[5] -1.25[6] -0.20[7]
2 GNA11 Guanine nucleotide-binding protein subunit alpha-11 [8] -1.89[9] -3.56[10] -3.61[11] -2.14[12] -1.34[13] -2.18[14]
3 ACSL4 Long-chain-fatty-acid--CoA ligase 4 [15] 1.50[16] 1.63[17] 1.93[18] 0.60[19] 1.43[20] 0.04[21]
4 GNAQ Guanine nucleotide-binding protein G(q) subunit alpha [22] -1.14[23] -1.96[24] -1.45[25] 0.64[26] 0.86[27] 0.51[28]
5 CD36 Platelet glycoprotein 4 [29] 0.12[30] -2.16[31] -7.24[32] 2.23[33] -6.77[34] 2.16[35]
6 PLCB3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [36] 0.79[37] -1.33[38] -0.86[39] 1.76[40] 1.41[41] -0.20[42]
7 PLCB1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [43] 1.57[44] 1.60[45] 1.03[46] -0.17[47] 0.32[48] 1.57[49]
8 PLCB2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [50] -2.84[51] -9.22[52] -11.06[53] -2.89[54] -3.60[55] 1.31[56]
9 GNA15 Guanine nucleotide-binding protein subunit alpha-15 [57] -4.60[58] -7.91[59] [60] -6.98[61] -3.42[62] -0.83[63]
10 GNA14 Guanine nucleotide-binding protein subunit alpha-14 [64] -7.28[65] -9.27[66] -8.11[67] -7.24[68] -4.15[69] 2.31[70]
11 FFAR1 Free fatty acid receptor 1 [71] [72] [73] [74] [75] [76] [77]
[1]
ref_hepatocyte ACSL3
Mean 17.7
Standard deviation 9.8
Values 33 11 21 10 12
[2]
HepG2 ACSL3
Mean 41.8
Standard deviation 11
Values 34 49
[3]
HepG2.C3A ACSL3
Mean 164
Standard deviation 67
Values 2.1e+02 1.2e+02
[4]
HuH.7 ACSL3
Mean 89.4
Standard deviation 16
Values 89 1.1e+02 74
[5]
SNU475 ACSL3
Mean 37.6
Standard deviation 1.8
Values 36 39
[6]
THLE ACSL3
Mean 29.6
Standard deviation 1.5
Values 29 31
[7]
liver ACSL3
Mean 41.4
Standard deviation 11
Values 28 50 50 37
[8]
ref_hepatocyte GNA11
Mean 10
Standard deviation 6.7
Values 19 12 12 3.8 2.8
[9]
HepG2 GNA11
Mean 14
Standard deviation 0.12
Values 14 14
[10]
HepG2.C3A GNA11
Mean 11.8
Standard deviation 0.77
Values 11 12
[11]
HuH.7 GNA11
Mean 10.9
Standard deviation 2.1
Values 13 11 8.6
[12]
SNU475 GNA11
Mean 8.12
Standard deviation 0.83
Values 8.7 7.5
[13]
THLE GNA11
Mean 15.8
Standard deviation 3.1
Values 14 18
[14]
liver GNA11
Mean 5.97
Standard deviation 1.7
Values 6.1 7 3.6 7.3
[15]
ref_hepatocyte ACSL4
Mean 8.43
Standard deviation 12
Values 30 3.6 4.9 2.5 1.3
[16]
HepG2 ACSL4
Mean 122
Standard deviation 39
Values 95 1.5e+02
[17]
HepG2.C3A ACSL4
Mean 362
Standard deviation 36
Values 3.9e+02 3.4e+02
[18]
HuH.7 ACSL4
Mean 426
Standard deviation 72
Values 4.8e+02 4.5e+02 3.5e+02
[19]
SNU475 ACSL4
Mean 45.3
Standard deviation 4
Values 42 48
[20]
THLE ACSL4
Mean 90.2
Standard deviation 2.5
Values 92 88
[21]
liver ACSL4
Mean 23.4
Standard deviation 10
Values 11 34 20 28
[22]
ref_hepatocyte GNAQ
Mean 1.88
Standard deviation 1
Values 1.6 2 3.6 1.1 1.1
[23]
HepG2 GNAQ
Mean 4.36
Standard deviation 1.2
Values 3.5 5.2
[24]
HepG2.C3A GNAQ
Mean 6.67
Standard deviation 0.93
Values 6 7.3
[25]
HuH.7 GNAQ
Mean 9.12
Standard deviation 3.7
Values 11 11 4.8
[26]
SNU475 GNAQ
Mean 10.4
Standard deviation 1.4
Values 11 9.4
[27]
THLE GNAQ
Mean 13.5
Standard deviation 3.4
Values 11 16
[28]
liver GNAQ
Mean 7.23
Standard deviation 3.8
Values 5.1 11 3 9.6
[29]
ref_hepatocyte CD36
Mean 1.74
Standard deviation 1.4
Values 3.5 0.39 0.28 1.9 2.6
[30]
HepG2 CD36
Mean 9.69
Standard deviation 5.6
Values 5.8 14
[31]
HepG2.C3A CD36
Mean 5.39
Standard deviation 3.6
Values 2.8 8
[32]
HuH.7 CD36
Mean 0.152
Standard deviation 0.061
Values 0.098 0.22 0.14
[33]
SNU475 CD36
Mean 28.9
Standard deviation 5.9
Values 25 33
[34]
THLE CD36
Mean 0.0633
Standard deviation 0.044
Values 0.095 0.032
[35]
liver CD36
Mean 20.9
Standard deviation 5.9
Values 22 24 25 12
[36]
ref_hepatocyte PLCB3
Mean 1.72
Standard deviation 1
Values 3.3 2 1.6 0.84 0.87
[37]
HepG2 PLCB3
Mean 15.2
Standard deviation 2.5
Values 13 17
[38]
HepG2.C3A PLCB3
Mean 9.48
Standard deviation 0.28
Values 9.3 9.7
[39]
HuH.7 PLCB3
Mean 12.5
Standard deviation 4.9
Values 15 6.9 16
[40]
SNU475 PLCB3
Mean 20.7
Standard deviation 4.4
Values 24 18
[41]
THLE PLCB3
Mean 18.1
Standard deviation 1.4
Values 17 19
[42]
liver PLCB3
Mean 4.04
Standard deviation 2.9
Values 1.7 5.4 1.5 7.5
[43]
ref_hepatocyte PLCB1
Mean 0.993
Standard deviation 1.3
Values 3.2 0.71 0.37 0.15 0.52
[44]
HepG2 PLCB1
Mean 15.2
Standard deviation 2.6
Values 13 17
[45]
HepG2.C3A PLCB1
Mean 41.8
Standard deviation 4.5
Values 45 39
[46]
HuH.7 PLCB1
Mean 26.9
Standard deviation 8.9
Values 26 36 19
[47]
SNU475 PLCB1
Mean 3.13
Standard deviation 0.39
Values 3.4 2.9
[48]
THLE PLCB1
Mean 4.93
Standard deviation 0.69
Values 5.4 4.4
[49]
liver PLCB1
Mean 7.93
Standard deviation 2.5
Values 8.6 11 6 6
[50]
ref_hepatocyte PLCB2
Mean 0.44
Standard deviation 0.47
Values 0 0.049 0.42 0.57 1.2
[51]
HepG2 PLCB2
Mean 0.316
Standard deviation 0.31
Values 0.53 0.099
[52]
HepG2.C3A PLCB2
Mean 0.0102
Standard deviation 0.00071
Values 0.0097 0.011
[53]
HuH.7 PLCB2
Mean 0.00273
Standard deviation 0.0047
Values 0.0082 0 0
[54]
SNU475 PLCB2
Mean 0.211
Standard deviation 0.062
Values 0.26 0.17
[55]
THLE PLCB2
Mean 0.145
Standard deviation 0.029
Values 0.12 0.16
[56]
liver PLCB2
Mean 2.94
Standard deviation 1.6
Values 1.8 3.5 1.5 4.9
[57]
ref_hepatocyte GNA15
Mean 0.271
Standard deviation 0.31
Values 0 0 0.27 0.33 0.76
[58]
HepG2 GNA15
Mean 0.0573
Standard deviation 0.081
Values 0.11 0
[59]
HepG2.C3A GNA15
Mean 0.0156
Standard deviation 0.0083
Values 0.0097 0.021
[60]
HuH.7 GNA15
Mean 0
Standard deviation 0
Values 0 0 0
[61]
SNU475 GNA15
Mean 0.0076
Standard deviation 0.011
Values 0 0.015
[62]
THLE GNA15
Mean 0.101
Standard deviation 0.0083
Values 0.095 0.11
[63]
liver GNA15
Mean 0.411
Standard deviation 0.3
Values 0.047 0.6 0.28 0.71
[64]
ref_hepatocyte GNA14
Mean 0.216
Standard deviation 0.25
Values 0 0.19 0 0.28 0.61
[65]
HepG2 GNA14
Mean 0.00716
Standard deviation 0.002
Values 0.0057 0.0086
[66]
HepG2.C3A GNA14
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[67]
HuH.7 GNA14
Mean 0.0103
Standard deviation 0.013
Values 0.025 0.0064 0
[68]
SNU475 GNA14
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[69]
THLE GNA14
Mean 0.0485
Standard deviation 0.023
Values 0.065 0.032
[70]
liver GNA14
Mean 2.89
Standard deviation 0.64
Values 3.5 2.1 3.3 2.7
[71]
ref_hepatocyte FFAR1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[72]
HepG2 FFAR1
Mean 0.0086
Standard deviation 0.012
Values 0.017 0
[73]
HepG2.C3A FFAR1
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[74]
HuH.7 FFAR1
Mean 0
Standard deviation 0
Values 0 0 0
[75]
SNU475 FFAR1
Mean 0
Standard deviation 0
Values 0 0
[76]
THLE FFAR1
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[77]
liver FFAR1
Mean 0
Standard deviation 0
Values 0 0 0 0