REACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_DEATH_GENES Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 PINK1 Serine/threonine-protein kinase PINK1, mitochondrial [1] -1.03[2] -0.50[3] -3.43[4] -0.94[5] -1.26[6] 0.18[7]
2 DDIT3 DNA damage-inducible transcript 3 protein [8] -1.89[9] -1.38[10] -1.53[11] -2.01[12] -1.25[13] -2.44[14]
3 CITED2 Cbp/p300-interacting transactivator 2 [15] -0.94[16] -1.38[17] 0.03[18] 0.00[19] -0.89[20] -1.73[21]
4 STK11 Serine/threonine-protein kinase STK11 [22] 0.00[23] -0.31[24] -0.03[25] -0.61[26] -0.37[27] -1.12[28]
5 NFYC Nuclear transcription factor Y subunit gamma [29] -0.21[30] -0.61[31] -0.50[32] -0.16[33] -0.97[34] -0.68[35]
6 BCL6 B-cell lymphoma 6 protein [36] -0.81[37] 1.18[38] -0.31[39] -0.45[40] 0.18[41] -0.23[42]
7 NFYB Nuclear transcription factor Y subunit beta [43] -0.55[44] 0.80[45] 0.20[46] 0.49[47] 0.71[48] -0.26[49]
8 BBC3 Bcl-2-binding component 3 [50] 0.82[51] 0.45[52] -0.02[53] -2.71[54] -2.07[55] -4.59[56]
9 NFYA Nuclear transcription factor Y subunit alpha [57] 1.63[58] 1.60[59] 1.50[60] 1.53[61] 0.87[62] 0.21[63]
10 FOXO3 Forkhead box protein O3 [64] 0.54[65] 0.37[66] 1.04[67] 0.50[68] 1.62[69] 2.08[70]
11 EP300 Histone acetyltransferase p300 [71] 2.81[72] 2.14[73] 3.07[74] 2.67[75] 2.60[76] 2.50[77]
12 CREBBP CREB-binding protein [78] 2.98[79] 1.94[80] 2.58[81] 2.85[82] 2.74[83] 2.98[84]
13 FOXO1 Forkhead box protein O1 [85] 1.78[86] 1.19[87] 1.36[88] 1.27[89] 3.17[90] 2.83[91]
14 BCL2L11 Bcl-2-like protein 11 [92] 1.59[93] 1.34[94] 1.70[95] 1.96[96] 0.82[97] 1.73[98]
15 FOXO4 Forkhead box protein O4 [99] 0.81[100] 0.96[101] 0.82[102] 0.26[103] 0.36[104] -0.95[105]
16 FASLG Tumor necrosis factor ligand superfamily member 6 [106] -3.73[107] -2.11[108] -6.05[109] [110] [111] 0.33[112]
[1]
ref_hepatocyte PINK1
Mean 28.5
Standard deviation 14
Values 12 23 24 48 35
[2]
HepG2 PINK1
Mean 29.1
Standard deviation 3.2
Values 31 27
[3]
HepG2.C3A PINK1
Mean 44.8
Standard deviation 19
Values 58 31
[4]
HuH.7 PINK1
Mean 5.5
Standard deviation 1.6
Values 4.7 7.3 4.5
[5]
SNU475 PINK1
Mean 25.6
Standard deviation 2.7
Values 28 24
[6]
THLE PINK1
Mean 24.8
Standard deviation 0.42
Values 25 24
[7]
liver PINK1
Mean 54.8
Standard deviation 20
Values 62 42 79 36
[8]
ref_hepatocyte DDIT3
Mean 23.4
Standard deviation 23
Values 7.5 13 17 64 15
[9]
HepG2 DDIT3
Mean 13.1
Standard deviation 8.7
Values 19 7
[10]
HepG2.C3A DDIT3
Mean 19.9
Standard deviation 9
Values 26 14
[11]
HuH.7 DDIT3
Mean 16.9
Standard deviation 6.4
Values 10 23 18
[12]
SNU475 DDIT3
Mean 10
Standard deviation 0.8
Values 9.5 11
[13]
THLE DDIT3
Mean 20.6
Standard deviation 4
Values 23 18
[14]
liver DDIT3
Mean 7.31
Standard deviation 5.6
Values 12 2.7 12 2.3
[15]
ref_hepatocyte CITED2
Mean 22.2
Standard deviation 7.4
Values 12 17 22 30 29
[16]
HepG2 CITED2
Mean 24
Standard deviation 6.9
Values 29 19
[17]
HepG2.C3A CITED2
Mean 18.8
Standard deviation 1.9
Values 20 17
[18]
HuH.7 CITED2
Mean 47.1
Standard deviation 14
Values 40 63 39
[19]
SNU475 CITED2
Mean 38.2
Standard deviation 1.3
Values 37 39
[20]
THLE CITED2
Mean 24.9
Standard deviation 4
Values 22 28
[21]
liver CITED2
Mean 11.3
Standard deviation 4.5
Values 12 17 10 6.3
[22]
ref_hepatocyte STK11
Mean 12.8
Standard deviation 5.7
Values 22 15 8 10 8.8
[23]
HepG2 STK11
Mean 26.5
Standard deviation 9.5
Values 33 20
[24]
HepG2.C3A STK11
Mean 22.8
Standard deviation 6.5
Values 27 18
[25]
HuH.7 STK11
Mean 25.9
Standard deviation 2.8
Values 26 23 29
[26]
SNU475 STK11
Mean 14.3
Standard deviation 1.5
Values 15 13
[27]
THLE STK11
Mean 20.5
Standard deviation 0.22
Values 21 20
[28]
liver STK11
Mean 9.97
Standard deviation 7.5
Values 3.6 17 3.3 16
[29]
ref_hepatocyte NFYC
Mean 10
Standard deviation 3.8
Values 16 5.5 8.7 11 9.2
[30]
HepG2 NFYC
Mean 18
Standard deviation 1.9
Values 17 19
[31]
HepG2.C3A NFYC
Mean 14.6
Standard deviation 0.89
Values 15 14
[32]
HuH.7 NFYC
Mean 14.8
Standard deviation 0.42
Values 15 15 15
[33]
SNU475 NFYC
Mean 15.5
Standard deviation 1
Values 16 15
[34]
THLE NFYC
Mean 10.7
Standard deviation 1.4
Values 9.7 12
[35]
liver NFYC
Mean 10.6
Standard deviation 6.2
Values 19 5 12 6.6
[36]
ref_hepatocyte BCL6
Mean 7.16
Standard deviation 3.9
Values 12 2 4.6 10 7.3
[37]
HepG2 BCL6
Mean 8.5
Standard deviation 0.79
Values 9.1 7.9
[38]
HepG2.C3A BCL6
Mean 36
Standard deviation 26
Values 55 17
[39]
HuH.7 BCL6
Mean 12
Standard deviation 6.8
Values 8.1 20 8.1
[40]
SNU475 BCL6
Mean 9.02
Standard deviation 1.2
Values 8.2 9.9
[41]
THLE BCL6
Mean 16.9
Standard deviation 0.91
Values 18 16
[42]
liver BCL6
Mean 10.4
Standard deviation 5.1
Values 7.1 11 6.1 17
[43]
ref_hepatocyte NFYB
Mean 4.68
Standard deviation 1.8
Values 4.3 7.4 2.9 3.6 5.2
[44]
HepG2 NFYB
Mean 6.64
Standard deviation 1.1
Values 5.8 7.5
[45]
HepG2.C3A NFYB
Mean 18
Standard deviation 5.3
Values 14 22
[46]
HuH.7 NFYB
Mean 11.1
Standard deviation 3
Values 12 7.7 13
[47]
SNU475 NFYB
Mean 11.3
Standard deviation 0.64
Values 12 11
[48]
THLE NFYB
Mean 16
Standard deviation 0.47
Values 16 16
[49]
liver NFYB
Mean 6.62
Standard deviation 2.1
Values 9.6 4.9 6.5 5.4
[50]
ref_hepatocyte BBC3
Mean 4.09
Standard deviation 4.3
Values 3.6 0.92 11 3.2 1.3
[51]
HepG2 BBC3
Mean 15.1
Standard deviation 11
Values 23 7
[52]
HepG2.C3A BBC3
Mean 12.4
Standard deviation 9.8
Values 19 5.5
[53]
HuH.7 BBC3
Mean 8.39
Standard deviation 3.1
Values 5.7 12 7.8
[54]
SNU475 BBC3
Mean 1.08
Standard deviation 0.44
Values 1.4 0.77
[55]
THLE BBC3
Mean 2.04
Standard deviation 0.082
Values 2.1 2
[56]
liver BBC3
Mean 0.288
Standard deviation 0.11
Values 0.24 0.3 0.18 0.44
[57]
ref_hepatocyte NFYA
Mean 3.88
Standard deviation 3.9
Values 11 3.4 1.1 2.2 1.9
[58]
HepG2 NFYA
Mean 25.1
Standard deviation 8.5
Values 19 31
[59]
HepG2.C3A NFYA
Mean 26
Standard deviation 6.6
Values 21 31
[60]
HuH.7 NFYA
Mean 22.9
Standard deviation 2.6
Values 26 20 23
[61]
SNU475 NFYA
Mean 19.3
Standard deviation 0.21
Values 19 19
[62]
THLE NFYA
Mean 14.8
Standard deviation 1.4
Values 14 16
[63]
liver NFYA
Mean 7.61
Standard deviation 3.9
Values 3.6 9.7 5.2 12
[64]
ref_hepatocyte FOXO3
Mean 2.79
Standard deviation 0.38
Values 3.3 2.7 2.3 2.8 2.9
[65]
HepG2 FOXO3
Mean 8.44
Standard deviation 1
Values 7.7 9.2
[66]
HepG2.C3A FOXO3
Mean 8
Standard deviation 2.4
Values 9.7 6.3
[67]
HuH.7 FOXO3
Mean 11.9
Standard deviation 3.6
Values 13 15 7.9
[68]
SNU475 FOXO3
Mean 6.76
Standard deviation 0.76
Values 7.3 6.2
[69]
THLE FOXO3
Mean 17.9
Standard deviation 3.1
Values 16 20
[70]
liver FOXO3
Mean 20
Standard deviation 5.5
Values 24 21 12 23
[71]
ref_hepatocyte EP300
Mean 2.46
Standard deviation 1.2
Values 3 1.8 4.4 1.4 1.8
[72]
HepG2 EP300
Mean 35.9
Standard deviation 5.7
Values 32 40
[73]
HepG2.C3A EP300
Mean 24.1
Standard deviation 1.4
Values 23 25
[74]
HuH.7 EP300
Mean 43
Standard deviation 15
Values 55 48 26
[75]
SNU475 EP300
Mean 26.9
Standard deviation 1.3
Values 28 26
[76]
THLE EP300
Mean 31.2
Standard deviation 11
Values 23 39
[77]
liver EP300
Mean 23.6
Standard deviation 8
Values 20 27 15 33
[78]
ref_hepatocyte CREBBP
Mean 1.78
Standard deviation 0.69
Values 1.8 0.72 2.6 1.9 1.9
[79]
HepG2 CREBBP
Mean 29.3
Standard deviation 2.8
Values 27 31
[80]
HepG2.C3A CREBBP
Mean 15.2
Standard deviation 1
Values 16 14
[81]
HuH.7 CREBBP
Mean 22.2
Standard deviation 7.2
Values 28 24 14
[82]
SNU475 CREBBP
Mean 22.1
Standard deviation 0.2
Values 22 22
[83]
THLE CREBBP
Mean 24.9
Standard deviation 7.3
Values 20 30
[84]
liver CREBBP
Mean 23.8
Standard deviation 6
Values 30 21 17 28
[85]
ref_hepatocyte FOXO1
Mean 1.77
Standard deviation 0.68
Values 0.71 1.7 2 1.9 2.6
[86]
HepG2 FOXO1
Mean 12.6
Standard deviation 1.8
Values 11 14
[87]
HepG2.C3A FOXO1
Mean 8.92
Standard deviation 1.5
Values 10 7.9
[88]
HuH.7 FOXO1
Mean 9.41
Standard deviation 1.6
Values 10 10 7.6
[89]
SNU475 FOXO1
Mean 7.33
Standard deviation 1.8
Values 8.6 6
[90]
THLE FOXO1
Mean 33.2
Standard deviation 1.9
Values 32 35
[91]
liver FOXO1
Mean 21.4
Standard deviation 7
Values 25 19 13 29
[92]
ref_hepatocyte BCL2L11
Mean 1.6
Standard deviation 0.72
Values 2.4 0.45 1.7 2 1.5
[93]
HepG2 BCL2L11
Mean 10.1
Standard deviation 0.76
Values 11 9.5
[94]
HepG2.C3A BCL2L11
Mean 9.01
Standard deviation 0.3
Values 8.8 9.2
[95]
HuH.7 BCL2L11
Mean 10.8
Standard deviation 1
Values 11 12 9.7
[96]
SNU475 BCL2L11
Mean 10.7
Standard deviation 3
Values 13 8.6
[97]
THLE BCL2L11
Mean 5.92
Standard deviation 0.75
Values 5.4 6.4
[98]
liver BCL2L11
Mean 9.03
Standard deviation 4.2
Values 7.8 6.5 6.5 15
[99]
ref_hepatocyte FOXO4
Mean 1.56
Standard deviation 0.85
Values 2.8 1.6 0.42 1.7 1.3
[100]
HepG2 FOXO4
Mean 5.71
Standard deviation 1.3
Values 6.6 4.8
[101]
HepG2.C3A FOXO4
Mean 6.69
Standard deviation 3.6
Values 9.2 4.2
[102]
HuH.7 FOXO4
Mean 5.72
Standard deviation 1.5
Values 5.1 7.5 4.6
[103]
SNU475 FOXO4
Mean 3.21
Standard deviation 1.1
Values 4 2.4
[104]
THLE FOXO4
Mean 4.17
Standard deviation 0.02
Values 4.2 4.2
[105]
liver FOXO4
Mean 1.37
Standard deviation 1.1
Values 0.54 2 0.33 2.6
[106]
ref_hepatocyte FASLG
Mean 0.0683
Standard deviation 0.15
Values 0 0 0 0 0.34
[107]
HepG2 FASLG
Mean 0.0107
Standard deviation 0.0091
Values 0.017 0.0043
[108]
HepG2.C3A FASLG
Mean 0.035
Standard deviation 0.019
Values 0.049 0.021
[109]
HuH.7 FASLG
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[110]
SNU475 FASLG
Mean 0
Standard deviation 0
Values 0 0
[111]
THLE FASLG
Mean 0
Standard deviation 0
Values 0 0
[112]
liver FASLG
Mean 0.145
Standard deviation 0.073
Values 0.19 0.043 0.21 0.15