REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | UBB | Polyubiquitin-B | [1] | -0.94[2] | -1.16[3] | -1.28[4] | -1.28[5] | -1.00[6] | -0.32[7] |
2 | RPS27A | Ubiquitin-40S ribosomal protein S27a | [8] | [9] | [10] | [11] | [12] | [13] | [14] |
3 | UBC | Polyubiquitin-C | [15] | -0.50[16] | -0.41[17] | -0.91[18] | -0.43[19] | -0.62[20] | 0.14[21] |
4 | SUMO1 | Small ubiquitin-related modifier 1 | [22] | -0.34[23] | -0.20[24] | -0.83[25] | 0.03[26] | -0.20[27] | 0.02[28] |
5 | SUMO2 | Small ubiquitin-related modifier 2 | [29] | 1.29[30] | 1.48[31] | 1.25[32] | 0.87[33] | 0.66[34] | -0.02[35] |
6 | UBA52 | Ubiquitin-60S ribosomal protein L40 | [36] | 1.93[37] | 1.83[38] | 2.60[39] | 0.97[40] | 1.61[41] | 0.91[42] |
7 | RBX1 | E3 ubiquitin-protein ligase RBX1 | [43] | -0.80[44] | -0.38[45] | -0.77[46] | -1.20[47] | -0.96[48] | -0.54[49] |
8 | CETN2 | Centrin-2 | [50] | -1.35[51] | -0.98[52] | -2.43[53] | -1.16[54] | -1.76[55] | -1.93[56] |
9 | PARP1 | Poly [ADP-ribose] polymerase 1 | [57] | 1.38[58] | 1.12[59] | 1.59[60] | 2.03[61] | 1.36[62] | 1.15[63] |
10 | RAD23B | UV excision repair protein RAD23 homolog B | [64] | 1.87[65] | 1.71[66] | 1.74[67] | 2.07[68] | 2.39[69] | 1.59[70] |
11 | RAD23A | UV excision repair protein RAD23 homolog A | [71] | 0.85[72] | 0.75[73] | 1.55[74] | 0.56[75] | 1.33[76] | 1.12[77] |
12 | DDB1 | DNA damage-binding protein 1 | [78] | 2.87[79] | 2.22[80] | 3.08[81] | 2.34[82] | 2.19[83] | 2.16[84] |
13 | SUMO3 | Small ubiquitin-related modifier 3 | [85] | 1.21[86] | 1.03[87] | 0.66[88] | 0.93[89] | 0.74[90] | 0.91[91] |
14 | RPA2 | Replication protein A 32 kDa subunit | [92] | -0.20[93] | -0.14[94] | 0.15[95] | 0.76[96] | 0.65[97] | -0.84[98] |
15 | UBE2N | Ubiquitin-conjugating enzyme E2 N | [99] | 1.94[100] | 2.41[101] | 0.96[102] | 1.82[103] | 1.53[104] | 0.84[105] |
16 | UBE2V2 | Ubiquitin-conjugating enzyme E2 variant 2 | [106] | -0.19[107] | 0.80[108] | 1.01[109] | 1.58[110] | 1.19[111] | 0.96[112] |
17 | CUL4A | Cullin-4A | [113] | 1.49[114] | 1.76[115] | 0.79[116] | 1.43[117] | 1.06[118] | 2.14[119] |
18 | CCNH | Cyclin-H | [120] | -0.41[121] | 0.43[122] | -0.45[123] | -0.28[124] | 0.93[125] | 0.64[126] |
19 | ERCC3 | TFIIH basal transcription factor complex helicase XPB subunit | [127] | 1.14[128] | 1.38[129] | 0.52[130] | 1.05[131] | 1.32[132] | 0.86[133] |
20 | ERCC1 | DNA excision repair protein ERCC-1 | [134] | 0.76[135] | 0.61[136] | 0.50[137] | 0.84[138] | 1.09[139] | 0.50[140] |
21 | CDK7 | Cyclin-dependent kinase 7 | [141] | 0.61[142] | 1.61[143] | 1.06[144] | 0.93[145] | 0.43[146] | -0.79[147] |
22 | CHD1L | Chromodomain-helicase-DNA-binding protein 1-like | [148] | 2.35[149] | 2.42[150] | 1.79[151] | 2.48[152] | 0.94[153] | 1.63[154] |
23 | UBE2I | SUMO-conjugating enzyme UBC9 | [155] | 2.55[156] | 2.21[157] | 2.32[158] | 1.83[159] | 2.21[160] | 1.01[161] |
24 | GTF2H2 | General transcription factor IIH subunit 2 | [162] | -4.15[163] | -3.21[164] | -3.70[165] | -3.68[166] | -5.11[167] | -3.11[168] |
25 | PARP2 | Poly [ADP-ribose] polymerase 2 | [169] | 1.18[170] | 0.80[171] | 1.28[172] | 1.22[173] | 1.82[174] | 0.09[175] |
26 | RPA1 | Replication protein A 70 kDa DNA-binding subunit | [176] | 2.57[177] | 2.29[178] | 2.29[179] | 3.35[180] | 3.19[181] | 1.56[182] |
27 | RPA3 | Replication protein A 14 kDa subunit | [183] | 0.89[184] | 1.68[185] | 2.13[186] | 0.59[187] | 0.70[188] | 0.87[189] |
28 | GTF2H1 | General transcription factor IIH subunit 1 | [190] | 1.48[191] | 1.65[192] | 1.32[193] | 2.09[194] | 1.47[195] | 1.72[196] |
29 | GTF2H4 | General transcription factor IIH subunit 4 | [197] | 1.01[198] | 1.46[199] | 1.28[200] | 1.82[201] | 0.86[202] | -0.10[203] |
30 | XPA | DNA repair protein complementing XP-A cells | [204] | -1.08[205] | -0.22[206] | -0.82[207] | -0.42[208] | -0.44[209] | 0.88[210] |
31 | CUL4B | Cullin-4B | [211] | 1.16[212] | 2.53[213] | 3.74[214] | 3.81[215] | 4.57[216] | 2.44[217] |
32 | DDB2 | DNA damage-binding protein 2 | [218] | 2.34[219] | 1.84[220] | 0.26[221] | -0.11[222] | 0.30[223] | 0.04[224] |
33 | ERCC5 | DNA repair protein complementing XP-G cells | [225] | -3.52[226] | -2.74[227] | -3.02[228] | -2.24[229] | -2.61[230] | -0.67[231] |
34 | MNAT1 | CDK-activating kinase assembly factor MAT1 | [232] | 0.64[233] | 1.93[234] | 0.84[235] | 1.88[236] | 1.25[237] | 0.61[238] |
35 | XPC | DNA repair protein complementing XP-C cells | [239] | 2.16[240] | 1.92[241] | 2.53[242] | 1.94[243] | 2.02[244] | 2.80[245] |
36 | GTF2H3 | General transcription factor IIH subunit 3 | [246] | 2.46[247] | 2.87[248] | 2.56[249] | 2.86[250] | 2.46[251] | 1.69[252] |
37 | ERCC2 | TFIIH basal transcription factor complex helicase XPD subunit | [253] | 2.37[254] | 2.41[255] | 2.58[256] | 2.82[257] | 2.56[258] | 0.73[259] |
38 | PIAS1 | E3 SUMO-protein ligase PIAS1 | [260] | 1.30[261] | 1.54[262] | 2.18[263] | 2.38[264] | 1.92[265] | 2.74[266] |
39 | GTF2H5 | General transcription factor IIH subunit 5 | [267] | 2.85[268] | 3.24[269] | 2.79[270] | 2.77[271] | 2.76[272] | 2.59[273] |
40 | RNF111 | E3 ubiquitin-protein ligase Arkadia | [274] | 2.86[275] | 2.67[276] | 2.95[277] | 3.93[278] | 3.43[279] | 3.85[280] |
41 | PIAS3 | E3 SUMO-protein ligase PIAS3 | [281] | 2.56[282] | 1.73[283] | 2.76[284] | 4.22[285] | 3.74[286] | 2.33[287] |
42 | ERCC4 | DNA repair endonuclease XPF | [288] | 3.47[289] | 3.14[290] | 3.04[291] | 3.73[292] | 3.70[293] | 3.97[294] |
43 | USP45 | Ubiquitin carboxyl-terminal hydrolase 45 | [295] | 2.67[296] | 4.25[297] | 3.42[298] | 4.26[299] | 4.12[300] | 4.58[301] |