REACTOME_FORMATION_OF_APOPTOSOME | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | DIABLO | Diablo homolog, mitochondrial | [1] | -0.88[2] | -0.95[3] | -1.27[4] | -1.33[5] | -1.34[6] | -1.51[7] |
2 | CYCS | Cytochrome c | [8] | 0.60[9] | 0.47[10] | 0.52[11] | 0.33[12] | 0.97[13] | 0.54[14] |
3 | APIP | Methylthioribulose-1-phosphate dehydratase | [15] | -2.40[16] | -2.01[17] | -1.81[18] | -2.54[19] | -2.83[20] | -2.00[21] |
4 | MAPK1 | Mitogen-activated protein kinase 1 | [22] | 0.98[23] | 0.79[24] | 0.59[25] | 0.85[26] | 0.73[27] | 0.99[28] |
5 | AVEN | Cell death regulator Aven | [29] | -1.71[30] | -2.30[31] | -4.41[32] | -2.06[33] | -1.73[34] | -1.99[35] |
6 | MAPK3 | Mitogen-activated protein kinase 3 | [36] | 1.12[37] | 0.83[38] | 0.86[39] | -0.58[40] | -0.32[41] | -1.82[42] |
7 | UACA | Uveal autoantigen with coiled-coil domains and ankyrin repeats | [43] | -1.03[44] | 0.84[45] | 0.89[46] | 1.87[47] | 0.78[48] | 1.00[49] |
8 | XIAP | E3 ubiquitin-protein ligase XIAP | [50] | 0.78[51] | 1.05[52] | 1.48[53] | 1.59[54] | 1.24[55] | 1.90[56] |
9 | CASP9 | Caspase-9 | [57] | -0.58[58] | 0.05[59] | -0.85[60] | -0.75[61] | -1.21[62] | -1.32[63] |
10 | CARD8 | Caspase recruitment domain-containing protein 8 | [64] | -0.92[65] | -0.45[66] | 0.66[67] | -0.29[68] | -0.04[69] | 0.64[70] |
11 | APAF1 | Apoptotic protease-activating factor 1 | [71] | 0.93[72] | 1.02[73] | 1.25[74] | 1.63[75] | 0.96[76] | 0.71[77] |