REACTOME_FGFR2_LIGAND_BINDING_AND_ACTIVATION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 FGF2 Fibroblast growth factor 2 [1] -4.31[2] -4.92[3] -2.82[4] 0.11[5] 0.69[6] -3.08[7]
2 FGFR2 Fibroblast growth factor receptor 2 [8] -0.13[9] 0.21[10] 2.10[11] 0.63[12] -5.20[13] 2.00[14]
3 FGF7 Fibroblast growth factor 7 [15] -6.92[16] -4.08[17] [18] -6.20[19] -2.92[20] -2.87[21]
4 FGFBP3 Fibroblast growth factor-binding protein 3 [22] 2.63[23] 2.18[24] -0.31[25] -2.63[26] -2.70[27] -4.45[28]
5 FGF5 Fibroblast growth factor 5 [29] 1.39[30] 1.85[31] -0.28[32] 0.66[33] -0.65[34] 1.72[35]
6 FGF1 Fibroblast growth factor 1 [36] -0.39[37] -0.46[38] -6.98[39] -0.24[40] 0.35[41] -1.38[42]
7 FGFBP2 Fibroblast growth factor-binding protein 2 [43] -2.65[44] -0.81[45] [46] -5.64[47] [48] -1.87[49]
8 FGF8 Fibroblast growth factor 8 [50] -0.95[51] -1.47[52] 0.97[53] -2.74[54] [55] 1.28[56]
9 FGF18 Fibroblast growth factor 18 [57] 4.16[58] -0.82[59] -0.71[60] -0.21[61] -0.61[62] -0.84[63]
10 FGF9 Fibroblast growth factor 9 [64] 4.64[65] 0.12[66] [67] 1.96[68] -4.15[69] -1.32[70]
11 FGF6 Fibroblast growth factor 6 [71] [72] [73] [74] [75] [76] [77]
12 FGFBP1 Fibroblast growth factor-binding protein 1 [78] [79] [80] [81] [82] [83] [84]
13 FGF4 Fibroblast growth factor 4 [85] [86] [87] [88] [89] [90] [91]
14 FGF16 Fibroblast growth factor 16 [92] [93] [94] [95] [96] [97] [98]
15 FGF20 Fibroblast growth factor 20 [99] [100] [101] [102] [103] [104] [105]
16 FGF23 Fibroblast growth factor 23 [106] [107] [108] [109] [110] [111] [112]
17 FGF3 Fibroblast growth factor 3 [113] [114] [115] [116] [117] [118] [119]
18 FGF17 Fibroblast growth factor 17 [120] [121] [122] [123] [124] [125] [126]
19 FGF22 Fibroblast growth factor 22 [127] [128] [129] [130] [131] [132] [133]
20 FGF10 Fibroblast growth factor 10 [134] [135] [136] [137] [138] [139] [140]
[1]
ref_hepatocyte FGF2
Mean 4.04
Standard deviation 6.5
Values 0.052 15 3.7 0.37 0.73
[2]
HepG2 FGF2
Mean 0.0866
Standard deviation 0.08
Values 0.14 0.03
[3]
HepG2.C3A FGF2
Mean 0.092
Standard deviation 0.0064
Values 0.087 0.097
[4]
HuH.7 FGF2
Mean 1.57
Standard deviation 0.89
Values 0.98 2.6 1.1
[5]
SNU475 FGF2
Mean 14.2
Standard deviation 1.3
Values 13 15
[6]
THLE FGF2
Mean 47.5
Standard deviation 0.66
Values 48 47
[7]
liver FGF2
Mean 1.81
Standard deviation 0.66
Values 1.9 2.5 0.9 2
[8]
ref_hepatocyte FGFR2
Mean 1.34
Standard deviation 1.4
Values 0.47 0.46 0.084 2.4 3.2
[9]
HepG2 FGFR2
Mean 0.519
Standard deviation 0.3
Values 0.3 0.73
[10]
HepG2.C3A FGFR2
Mean 1.07
Standard deviation 0.3
Values 0.86 1.3
[11]
HuH.7 FGFR2
Mean 15.7
Standard deviation 0.71
Values 16 15 16
[12]
SNU475 FGFR2
Mean 6.74
Standard deviation 6.4
Values 11 2.2
[13]
THLE FGFR2
Mean 0.263
Standard deviation 0.0039
Values 0.27 0.26
[14]
liver FGFR2
Mean 20.4
Standard deviation 8
Values 18 19 13 32
[15]
ref_hepatocyte FGF7
Mean 0.61
Standard deviation 0.64
Values 0 0.3 0.46 0.6 1.7
[16]
HepG2 FGF7
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[17]
HepG2.C3A FGF7
Mean 0.0248
Standard deviation 0.02
Values 0.039 0.011
[18]
HuH.7 FGF7
Mean 0
Standard deviation 0
Values 0 0 0
[19]
SNU475 FGF7
Mean 0.027
Standard deviation 0.012
Values 0.019 0.035
[20]
THLE FGF7
Mean 0.584
Standard deviation 0.1
Values 0.66 0.51
[21]
liver FGF7
Mean 0.317
Standard deviation 0.15
Values 0.28 0.31 0.51 0.16
[22]
ref_hepatocyte FGFBP3
Mean 0.557
Standard deviation 0.67
Values 1.6 0 0.83 0.16 0.19
[23]
HepG2 FGFBP3
Mean 1.46
Standard deviation 0.34
Values 1.7 1.2
[24]
HepG2.C3A FGFBP3
Mean 1.73
Standard deviation 0.37
Values 1.5 2
[25]
HuH.7 FGFBP3
Mean 1.23
Standard deviation 0.42
Values 0.77 1.6 1.3
[26]
SNU475 FGFBP3
Mean 0.294
Standard deviation 0.1
Values 0.22 0.36
[27]
THLE FGFBP3
Mean 0.622
Standard deviation 0.068
Values 0.57 0.67
[28]
liver FGFBP3
Mean 0.097
Standard deviation 0.032
Values 0.12 0.1 0.051 0.12
[29]
ref_hepatocyte FGF5
Mean 0.241
Standard deviation 0.27
Values 0.042 0.036 0.09 0.64 0.4
[30]
HepG2 FGF5
Mean 0.268
Standard deviation 0.022
Values 0.25 0.28
[31]
HepG2.C3A FGF5
Mean 0.596
Standard deviation 0.024
Values 0.61 0.58
[32]
HuH.7 FGF5
Mean 0.543
Standard deviation 0.15
Values 0.62 0.65 0.37
[33]
SNU475 FGF5
Mean 1.24
Standard deviation 0.35
Values 0.99 1.5
[34]
THLE FGF5
Mean 1.11
Standard deviation 0.17
Values 0.99 1.2
[35]
liver FGF5
Mean 3.01
Standard deviation 1.5
Values 2.3 4.5 1.2 4.1
[36]
ref_hepatocyte FGF1
Mean 0.126
Standard deviation 0.27
Values 0 0.6 0 0 0.024
[37]
HepG2 FGF1
Mean 0.0408
Standard deviation 0.04
Values 0.069 0.013
[38]
HepG2.C3A FGF1
Mean 0.0628
Standard deviation 0.048
Values 0.029 0.097
[39]
HuH.7 FGF1
Mean 0.00273
Standard deviation 0.0047
Values 0.0082 0 0
[40]
SNU475 FGF1
Mean 0.346
Standard deviation 0.077
Values 0.29 0.4
[41]
THLE FGF1
Mean 1.16
Standard deviation 0.44
Values 0.85 1.5
[42]
liver FGF1
Mean 0.184
Standard deviation 0.042
Values 0.14 0.21 0.15 0.23
[43]
ref_hepatocyte FGFBP2
Mean 0.117
Standard deviation 0.16
Values 0 0 0 0.24 0.34
[44]
HepG2 FGFBP2
Mean 0.00788
Standard deviation 0.0051
Values 0.011 0.0043
[45]
HepG2.C3A FGFBP2
Mean 0.0458
Standard deviation 0.004
Values 0.049 0.043
[46]
HuH.7 FGFBP2
Mean 0
Standard deviation 0
Values 0 0 0
[47]
SNU475 FGFBP2
Mean 0.0076
Standard deviation 0.011
Values 0 0.015
[48]
THLE FGFBP2
Mean 0
Standard deviation 0
Values 0 0
[49]
liver FGFBP2
Mean 0.121
Standard deviation 0.085
Values 0.071 0.14 0.23 0.04
[50]
ref_hepatocyte FGF8
Mean 0.0195
Standard deviation 0.044
Values 0 0 0 0 0.098
[51]
HepG2 FGF8
Mean 0.00429
Standard deviation 0.0061
Values 0 0.0086
[52]
HepG2.C3A FGF8
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[53]
HuH.7 FGF8
Mean 0.105
Standard deviation 0.073
Values 0.19 0.051 0.075
[54]
SNU475 FGF8
Mean 0.00949
Standard deviation 0.0063
Values 0.014 0.0051
[55]
THLE FGF8
Mean 0
Standard deviation 0
Values 0 0
[56]
liver FGF8
Mean 0.18
Standard deviation 0.14
Values 0.047 0.34 0.077 0.25
[57]
ref_hepatocyte FGF18
Mean 0.0138
Standard deviation 0.031
Values 0 0 0 0.069 0
[58]
HepG2 FGF18
Mean 0.105
Standard deviation 0.039
Values 0.13 0.077
[59]
HepG2.C3A FGF18
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[60]
HuH.7 FGF18
Mean 0.0232
Standard deviation 0.02
Values 0 0.032 0.037
[61]
SNU475 FGF18
Mean 0.0388
Standard deviation 0.0024
Values 0.037 0.041
[62]
THLE FGF18
Mean 0.0657
Standard deviation 0.033
Values 0.089 0.043
[63]
liver FGF18
Mean 0.0294
Standard deviation 0.0072
Values 0.024 0.029 0.026 0.04
[64]
ref_hepatocyte FGF9
Mean 0.0065
Standard deviation 0.015
Values 0 0 0 0 0.033
[65]
HepG2 FGF9
Mean 0.0687
Standard deviation 9.1e-05
Values 0.069 0.069
[66]
HepG2.C3A FGF9
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[67]
HuH.7 FGF9
Mean 0
Standard deviation 0
Values 0 0 0
[68]
SNU475 FGF9
Mean 0.0822
Standard deviation 0.08
Values 0.14 0.025
[69]
THLE FGF9
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[70]
liver FGF9
Mean 0.00993
Standard deviation 0.02
Values 0 0 0 0.04
[71]
ref_hepatocyte FGF6
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[72]
HepG2 FGF6
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[73]
HepG2.C3A FGF6
Mean 0
Standard deviation 0
Values 0 0
[74]
HuH.7 FGF6
Mean 0
Standard deviation 0
Values 0 0 0
[75]
SNU475 FGF6
Mean 0
Standard deviation 0
Values 0 0
[76]
THLE FGF6
Mean 0
Standard deviation 0
Values 0 0
[77]
liver FGF6
Mean 0.00357
Standard deviation 0.0071
Values 0 0.014 0 0
[78]
ref_hepatocyte FGFBP1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[79]
HepG2 FGFBP1
Mean 0.00858
Standard deviation 0.012
Values 0 0.017
[80]
HepG2.C3A FGFBP1
Mean 0
Standard deviation 0
Values 0 0
[81]
HuH.7 FGFBP1
Mean 0
Standard deviation 0
Values 0 0 0
[82]
SNU475 FGFBP1
Mean 0.0327
Standard deviation 0.04
Values 0.0046 0.061
[83]
THLE FGFBP1
Mean 0.0166
Standard deviation 0.0067
Values 0.012 0.021
[84]
liver FGFBP1
Mean 0.00357
Standard deviation 0.0071
Values 0 0.014 0 0
[85]
ref_hepatocyte FGF4
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[86]
HepG2 FGF4
Mean 0
Standard deviation 0
Values 0 0
[87]
HepG2.C3A FGF4
Mean 0
Standard deviation 0
Values 0 0
[88]
HuH.7 FGF4
Mean 0
Standard deviation 0
Values 0 0 0
[89]
SNU475 FGF4
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[90]
THLE FGF4
Mean 0
Standard deviation 0
Values 0 0
[91]
liver FGF4
Mean 0
Standard deviation 0
Values 0 0 0 0
[92]
ref_hepatocyte FGF16
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[93]
HepG2 FGF16
Mean 0
Standard deviation 0
Values 0 0
[94]
HepG2.C3A FGF16
Mean 0
Standard deviation 0
Values 0 0
[95]
HuH.7 FGF16
Mean 0
Standard deviation 0
Values 0 0 0
[96]
SNU475 FGF16
Mean 0
Standard deviation 0
Values 0 0
[97]
THLE FGF16
Mean 0
Standard deviation 0
Values 0 0
[98]
liver FGF16
Mean 0.0118
Standard deviation 0.024
Values 0.047 0 0 0
[99]
ref_hepatocyte FGF20
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[100]
HepG2 FGF20
Mean 0.0115
Standard deviation 0.016
Values 0.023 0
[101]
HepG2.C3A FGF20
Mean 0
Standard deviation 0
Values 0 0
[102]
HuH.7 FGF20
Mean 0
Standard deviation 0
Values 0 0 0
[103]
SNU475 FGF20
Mean 0.00485
Standard deviation 0.0003
Values 0.0046 0.0051
[104]
THLE FGF20
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[105]
liver FGF20
Mean 0.0118
Standard deviation 0.024
Values 0.047 0 0 0
[106]
ref_hepatocyte FGF23
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[107]
HepG2 FGF23
Mean 0
Standard deviation 0
Values 0 0
[108]
HepG2.C3A FGF23
Mean 0
Standard deviation 0
Values 0 0
[109]
HuH.7 FGF23
Mean 0.00312
Standard deviation 0.0054
Values 0 0 0.0094
[110]
SNU475 FGF23
Mean 0
Standard deviation 0
Values 0 0
[111]
THLE FGF23
Mean 0
Standard deviation 0
Values 0 0
[112]
liver FGF23
Mean 0.68
Standard deviation 0.31
Values 0.59 0.67 1.1 0.36
[113]
ref_hepatocyte FGF3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[114]
HepG2 FGF3
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[115]
HepG2.C3A FGF3
Mean 0
Standard deviation 0
Values 0 0
[116]
HuH.7 FGF3
Mean 0.00487
Standard deviation 0.0043
Values 0.0082 0.0064 0
[117]
SNU475 FGF3
Mean 0.00717
Standard deviation 0.003
Values 0.0093 0.0051
[118]
THLE FGF3
Mean 0
Standard deviation 0
Values 0 0
[119]
liver FGF3
Mean 0
Standard deviation 0
Values 0 0 0 0
[120]
ref_hepatocyte FGF17
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[121]
HepG2 FGF17
Mean 0.398
Standard deviation 0.15
Values 0.5 0.29
[122]
HepG2.C3A FGF17
Mean 1.23
Standard deviation 1.1
Values 2 0.46
[123]
HuH.7 FGF17
Mean 0.183
Standard deviation 0.2
Values 0.074 0.41 0.066
[124]
SNU475 FGF17
Mean 0.00232
Standard deviation 0.0033
Values 0.0046 0
[125]
THLE FGF17
Mean 0.0228
Standard deviation 0.0096
Values 0.03 0.016
[126]
liver FGF17
Mean 0.00588
Standard deviation 0.012
Values 0.024 0 0 0
[127]
ref_hepatocyte FGF22
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[128]
HepG2 FGF22
Mean 0.01
Standard deviation 0.002
Values 0.011 0.0086
[129]
HepG2.C3A FGF22
Mean 0
Standard deviation 0
Values 0 0
[130]
HuH.7 FGF22
Mean 0.00625
Standard deviation 0.011
Values 0 0 0.019
[131]
SNU475 FGF22
Mean 0.00464
Standard deviation 0.0066
Values 0.0093 0
[132]
THLE FGF22
Mean 0
Standard deviation 0
Values 0 0
[133]
liver FGF22
Mean 0
Standard deviation 0
Values 0 0 0 0
[134]
ref_hepatocyte FGF10
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[135]
HepG2 FGF10
Mean 0
Standard deviation 0
Values 0 0
[136]
HepG2.C3A FGF10
Mean 0
Standard deviation 0
Values 0 0
[137]
HuH.7 FGF10
Mean 0
Standard deviation 0
Values 0 0 0
[138]
SNU475 FGF10
Mean 0
Standard deviation 0
Values 0 0
[139]
THLE FGF10
Mean 0
Standard deviation 0
Values 0 0
[140]
liver FGF10
Mean 0.0234
Standard deviation 0.038
Values 0 0.014 0 0.079