REACTOME_FGFR1_MUTANT_RECEPTOR_ACTIVATION | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | STAT3 | Signal transducer and activator of transcription 3 | [1] | -0.25[2] | -1.50[3] | -1.25[4] | -0.95[5] | -1.18[6] | 0.83[7] |
2 | GRB2 | Growth factor receptor-bound protein 2 | [8] | 0.39[9] | 0.48[10] | 0.11[11] | -0.64[12] | -0.22[13] | -1.27[14] |
3 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | [15] | -0.88[16] | -1.55[17] | -0.93[18] | 1.34[19] | -0.43[20] | -0.62[21] |
4 | LRRFIP1 | Leucine-rich repeat flightless-interacting protein 1 | [22] | -1.46[23] | -0.71[24] | -1.90[25] | -1.54[26] | -0.45[27] | -0.89[28] |
5 | TRIM24 | Transcription intermediary factor 1-alpha | [29] | 1.03[30] | 0.40[31] | 0.02[32] | -2.89[33] | -2.13[34] | -1.69[35] |
6 | FGFR1OP2 | FGFR1 oncogene partner 2 | [36] | -2.14[37] | -0.77[38] | -1.21[39] | -2.54[40] | -1.29[41] | -1.89[42] |
7 | ERLIN2 | Erlin-2 | [43] | -0.02[44] | 0.38[45] | 0.86[46] | -0.94[47] | -0.53[48] | -0.86[49] |
8 | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha | [50] | -1.28[51] | -0.91[52] | -0.31[53] | 0.87[54] | 0.88[55] | 1.43[56] |
9 | MYO18A | Unconventional myosin-XVIIIa | [57] | 0.27[58] | 0.81[59] | 1.22[60] | -0.16[61] | -0.64[62] | 1.04[63] |
10 | CUX1 | Homeobox protein cut-like 1 | [64] | 0.73[65] | 0.12[66] | 0.26[67] | 0.44[68] | 1.35[69] | -0.09[70] |
11 | CPSF6 | Cleavage and polyadenylation specificity factor subunit 6 | [71] | 0.65[72] | 1.54[73] | 1.24[74] | 0.71[75] | 1.02[76] | 0.21[77] |
12 | FGF2 | Fibroblast growth factor 2 | [78] | -7.49[79] | -6.99[80] | -3.32[81] | -0.26[82] | 1.82[83] | -3.24[84] |
13 | STAT5B | Signal transducer and activator of transcription 5B | [85] | 0.55[86] | 0.43[87] | 0.64[88] | 0.36[89] | 0.00[90] | 0.05[91] |
14 | BCR | Breakpoint cluster region protein | [92] | 1.42[93] | 0.92[94] | 0.68[95] | -0.17[96] | 0.70[97] | 0.13[98] |
15 | BAG4 | BAG family molecular chaperone regulator 4 | [99] | -0.45[100] | 0.75[101] | 1.56[102] | -1.25[103] | -0.53[104] | 0.25[105] |
16 | STAT5A | Signal transducer and activator of transcription 5A | [106] | -2.76[107] | -1.33[108] | -2.75[109] | -2.04[110] | -0.78[111] | -1.34[112] |
17 | ZMYM2 | Zinc finger MYM-type protein 2 | [113] | 0.82[114] | 2.21[115] | 1.24[116] | 1.78[117] | 1.81[118] | 1.71[119] |
18 | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | -1.19[120] | 0.70[121] | 0.40[122] | -0.06[123] | 0.64[124] | 0.34[125] | |
19 | GAB2 | GRB2-associated-binding protein 2 | [126] | 0.76[127] | 0.80[128] | 0.56[129] | -0.27[130] | 0.32[131] | -1.03[132] |
20 | FGFR1 | Fibroblast growth factor receptor 1 | [133] | 3.77[134] | 2.34[135] | 3.50[136] | 3.87[137] | 3.63[138] | 0.09[139] |
21 | CNTRL | Centriolin | [140] | 0.20[141] | 2.69[142] | 3.05[143] | 1.56[144] | 1.77[145] | 1.01[146] |
22 | FGF5 | Fibroblast growth factor 5 | [147] | -1.80[148] | -0.22[149] | -0.79[150] | 0.29[151] | 0.48[152] | 1.56[153] |
23 | FGF1 | Fibroblast growth factor 1 | [154] | -3.57[155] | -2.53[156] | -7.48[157] | -0.61[158] | 1.47[159] | -1.53[160] |
24 | FGF8 | Fibroblast growth factor 8 | [161] | -4.13[162] | -3.54[163] | 0.47[164] | -3.11[165] | [166] | 1.12[167] |
25 | FGF9 | Fibroblast growth factor 9 | [168] | 1.45[169] | -1.95[170] | [171] | 1.59[172] | -3.02[173] | -1.47[174] |
26 | FGF4 | Fibroblast growth factor 4 | [175] | [176] | [177] | [178] | [179] | [180] | [181] |
27 | FGF20 | Fibroblast growth factor 20 | [182] | [183] | [184] | [185] | [186] | [187] | [188] |
28 | FGF23 | Fibroblast growth factor 23 | [189] | [190] | [191] | [192] | [193] | [194] | [195] |
29 | FGF17 | Fibroblast growth factor 17 | [196] | [197] | [198] | [199] | [200] | [201] | [202] |
30 | CEP43 | [203] | [204] | [205] | [206] | [207] | [208] | [209] | |
31 | FGF6 | Fibroblast growth factor 6 | [210] | [211] | [212] | [213] | [214] | [215] | [216] |