REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 FGF2 Fibroblast growth factor 2 [1] -8.53[2] -6.78[3] -4.15[4] -1.76[5] -0.36[6] -2.02[7]
2 FGFR1 Fibroblast growth factor receptor 1 [8] 2.73[9] 2.54[10] 2.67[11] 2.36[12] 1.45[13] 1.31[14]
3 KL Klotho [15] -7.90[16] [17] [18] -4.09[19] -9.52[20] -0.11[21]
4 FGF5 Fibroblast growth factor 5 [22] -2.83[23] -0.02[24] -1.62[25] -1.22[26] -1.71[27] 2.78[28]
5 FGF1 Fibroblast growth factor 1 [29] -4.61[30] -2.33[31] -8.31[32] -2.11[33] -0.71[34] -0.31[35]
6 FGF8 Fibroblast growth factor 8 [36] -5.17[37] -3.33[38] -0.36[39] -4.61[40] [41] 2.34[42]
7 FGF9 Fibroblast growth factor 9 [43] 0.42[44] -1.75[45] [46] 0.09[47] -5.21[48] -0.25[49]
8 ANOS1 Anosmin-1 [50] [51] [52] [53] [54] [55] [56]
9 FGF6 Fibroblast growth factor 6 [57] [58] [59] [60] [61] [62] [63]
10 FGF4 Fibroblast growth factor 4 [64] [65] [66] [67] [68] [69] [70]
11 FGF17 Fibroblast growth factor 17 [71] [72] [73] [74] [75] [76] [77]
12 FGF22 Fibroblast growth factor 22 [78] [79] [80] [81] [82] [83] [84]
13 FGF10 Fibroblast growth factor 10 [85] [86] [87] [88] [89] [90] [91]
14 FGF23 Fibroblast growth factor 23 [92] [93] [94] [95] [96] [97] [98]
15 FGF20 Fibroblast growth factor 20 [99] [100] [101] [102] [103] [104] [105]
16 FGF3 Fibroblast growth factor 3 [106] [107] [108] [109] [110] [111] [112]
[1]
ref_hepatocyte FGF2
Mean 4.04
Standard deviation 6.5
Values 0.052 15 3.7 0.37 0.73
[2]
HepG2 FGF2
Mean 0.0866
Standard deviation 0.08
Values 0.14 0.03
[3]
HepG2.C3A FGF2
Mean 0.092
Standard deviation 0.0064
Values 0.087 0.097
[4]
HuH.7 FGF2
Mean 1.57
Standard deviation 0.89
Values 0.98 2.6 1.1
[5]
SNU475 FGF2
Mean 14.2
Standard deviation 1.3
Values 13 15
[6]
THLE FGF2
Mean 47.5
Standard deviation 0.66
Values 48 47
[7]
liver FGF2
Mean 1.81
Standard deviation 0.66
Values 1.9 2.5 0.9 2
[8]
ref_hepatocyte FGFR1
Mean 0.81
Standard deviation 0.63
Values 1.2 0.49 1.6 0.06 0.62
[9]
HepG2 FGFR1
Mean 42.7
Standard deviation 4
Values 40 46
[10]
HepG2.C3A FGFR1
Mean 11.8
Standard deviation 3.5
Values 9.3 14
[11]
HuH.7 FGFR1
Mean 35.6
Standard deviation 13
Values 43 20 43
[12]
SNU475 FGFR1
Mean 49.5
Standard deviation 1.4
Values 50 49
[13]
THLE FGFR1
Mean 33.4
Standard deviation 3.3
Values 36 31
[14]
liver FGFR1
Mean 3.64
Standard deviation 0.67
Values 3 4.2 3.2 4.3
[15]
ref_hepatocyte KL
Mean 0.258
Standard deviation 0.29
Values 0 0 0.4 0.2 0.69
[16]
HepG2 KL
Mean 0.00858
Standard deviation 0.012
Values 0 0.017
[17]
HepG2.C3A KL
Mean 0
Standard deviation 0
Values 0 0
[18]
HuH.7 KL
Mean 0
Standard deviation 0
Values 0 0 0
[19]
SNU475 KL
Mean 0.181
Standard deviation 0.026
Values 0.2 0.16
[20]
THLE KL
Mean 0.00532
Standard deviation 0.0075
Values 0 0.011
[21]
liver KL
Mean 0.436
Standard deviation 0.32
Values 0.38 0.31 0.15 0.9
[22]
ref_hepatocyte FGF5
Mean 0.241
Standard deviation 0.27
Values 0.042 0.036 0.09 0.64 0.4
[23]
HepG2 FGF5
Mean 0.268
Standard deviation 0.022
Values 0.25 0.28
[24]
HepG2.C3A FGF5
Mean 0.596
Standard deviation 0.024
Values 0.61 0.58
[25]
HuH.7 FGF5
Mean 0.543
Standard deviation 0.15
Values 0.62 0.65 0.37
[26]
SNU475 FGF5
Mean 1.24
Standard deviation 0.35
Values 0.99 1.5
[27]
THLE FGF5
Mean 1.11
Standard deviation 0.17
Values 0.99 1.2
[28]
liver FGF5
Mean 3.01
Standard deviation 1.5
Values 2.3 4.5 1.2 4.1
[29]
ref_hepatocyte FGF1
Mean 0.126
Standard deviation 0.27
Values 0 0.6 0 0 0.024
[30]
HepG2 FGF1
Mean 0.0408
Standard deviation 0.04
Values 0.069 0.013
[31]
HepG2.C3A FGF1
Mean 0.0628
Standard deviation 0.048
Values 0.029 0.097
[32]
HuH.7 FGF1
Mean 0.00273
Standard deviation 0.0047
Values 0.0082 0 0
[33]
SNU475 FGF1
Mean 0.346
Standard deviation 0.077
Values 0.29 0.4
[34]
THLE FGF1
Mean 1.16
Standard deviation 0.44
Values 0.85 1.5
[35]
liver FGF1
Mean 0.184
Standard deviation 0.042
Values 0.14 0.21 0.15 0.23
[36]
ref_hepatocyte FGF8
Mean 0.0195
Standard deviation 0.044
Values 0 0 0 0 0.098
[37]
HepG2 FGF8
Mean 0.00429
Standard deviation 0.0061
Values 0 0.0086
[38]
HepG2.C3A FGF8
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[39]
HuH.7 FGF8
Mean 0.105
Standard deviation 0.073
Values 0.19 0.051 0.075
[40]
SNU475 FGF8
Mean 0.00949
Standard deviation 0.0063
Values 0.014 0.0051
[41]
THLE FGF8
Mean 0
Standard deviation 0
Values 0 0
[42]
liver FGF8
Mean 0.18
Standard deviation 0.14
Values 0.047 0.34 0.077 0.25
[43]
ref_hepatocyte FGF9
Mean 0.0065
Standard deviation 0.015
Values 0 0 0 0 0.033
[44]
HepG2 FGF9
Mean 0.0687
Standard deviation 9.1e-05
Values 0.069 0.069
[45]
HepG2.C3A FGF9
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[46]
HuH.7 FGF9
Mean 0
Standard deviation 0
Values 0 0 0
[47]
SNU475 FGF9
Mean 0.0822
Standard deviation 0.08
Values 0.14 0.025
[48]
THLE FGF9
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[49]
liver FGF9
Mean 0.00993
Standard deviation 0.02
Values 0 0 0 0.04
[50]
ref_hepatocyte ANOS1
Missing
[51]
HepG2 ANOS1
Missing
[52]
HepG2.C3A ANOS1
Missing
[53]
HuH.7 ANOS1
Missing
[54]
SNU475 ANOS1
Missing
[55]
THLE ANOS1
Missing
[56]
liver ANOS1
Missing
[57]
ref_hepatocyte FGF6
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[58]
HepG2 FGF6
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[59]
HepG2.C3A FGF6
Mean 0
Standard deviation 0
Values 0 0
[60]
HuH.7 FGF6
Mean 0
Standard deviation 0
Values 0 0 0
[61]
SNU475 FGF6
Mean 0
Standard deviation 0
Values 0 0
[62]
THLE FGF6
Mean 0
Standard deviation 0
Values 0 0
[63]
liver FGF6
Mean 0.00357
Standard deviation 0.0071
Values 0 0.014 0 0
[64]
ref_hepatocyte FGF4
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[65]
HepG2 FGF4
Mean 0
Standard deviation 0
Values 0 0
[66]
HepG2.C3A FGF4
Mean 0
Standard deviation 0
Values 0 0
[67]
HuH.7 FGF4
Mean 0
Standard deviation 0
Values 0 0 0
[68]
SNU475 FGF4
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[69]
THLE FGF4
Mean 0
Standard deviation 0
Values 0 0
[70]
liver FGF4
Mean 0
Standard deviation 0
Values 0 0 0 0
[71]
ref_hepatocyte FGF17
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[72]
HepG2 FGF17
Mean 0.398
Standard deviation 0.15
Values 0.5 0.29
[73]
HepG2.C3A FGF17
Mean 1.23
Standard deviation 1.1
Values 2 0.46
[74]
HuH.7 FGF17
Mean 0.183
Standard deviation 0.2
Values 0.074 0.41 0.066
[75]
SNU475 FGF17
Mean 0.00232
Standard deviation 0.0033
Values 0.0046 0
[76]
THLE FGF17
Mean 0.0228
Standard deviation 0.0096
Values 0.03 0.016
[77]
liver FGF17
Mean 0.00588
Standard deviation 0.012
Values 0.024 0 0 0
[78]
ref_hepatocyte FGF22
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[79]
HepG2 FGF22
Mean 0.01
Standard deviation 0.002
Values 0.011 0.0086
[80]
HepG2.C3A FGF22
Mean 0
Standard deviation 0
Values 0 0
[81]
HuH.7 FGF22
Mean 0.00625
Standard deviation 0.011
Values 0 0 0.019
[82]
SNU475 FGF22
Mean 0.00464
Standard deviation 0.0066
Values 0.0093 0
[83]
THLE FGF22
Mean 0
Standard deviation 0
Values 0 0
[84]
liver FGF22
Mean 0
Standard deviation 0
Values 0 0 0 0
[85]
ref_hepatocyte FGF10
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[86]
HepG2 FGF10
Mean 0
Standard deviation 0
Values 0 0
[87]
HepG2.C3A FGF10
Mean 0
Standard deviation 0
Values 0 0
[88]
HuH.7 FGF10
Mean 0
Standard deviation 0
Values 0 0 0
[89]
SNU475 FGF10
Mean 0
Standard deviation 0
Values 0 0
[90]
THLE FGF10
Mean 0
Standard deviation 0
Values 0 0
[91]
liver FGF10
Mean 0.0234
Standard deviation 0.038
Values 0 0.014 0 0.079
[92]
ref_hepatocyte FGF23
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[93]
HepG2 FGF23
Mean 0
Standard deviation 0
Values 0 0
[94]
HepG2.C3A FGF23
Mean 0
Standard deviation 0
Values 0 0
[95]
HuH.7 FGF23
Mean 0.00312
Standard deviation 0.0054
Values 0 0 0.0094
[96]
SNU475 FGF23
Mean 0
Standard deviation 0
Values 0 0
[97]
THLE FGF23
Mean 0
Standard deviation 0
Values 0 0
[98]
liver FGF23
Mean 0.68
Standard deviation 0.31
Values 0.59 0.67 1.1 0.36
[99]
ref_hepatocyte FGF20
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[100]
HepG2 FGF20
Mean 0.0115
Standard deviation 0.016
Values 0.023 0
[101]
HepG2.C3A FGF20
Mean 0
Standard deviation 0
Values 0 0
[102]
HuH.7 FGF20
Mean 0
Standard deviation 0
Values 0 0 0
[103]
SNU475 FGF20
Mean 0.00485
Standard deviation 0.0003
Values 0.0046 0.0051
[104]
THLE FGF20
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[105]
liver FGF20
Mean 0.0118
Standard deviation 0.024
Values 0.047 0 0 0
[106]
ref_hepatocyte FGF3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[107]
HepG2 FGF3
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[108]
HepG2.C3A FGF3
Mean 0
Standard deviation 0
Values 0 0
[109]
HuH.7 FGF3
Mean 0.00487
Standard deviation 0.0043
Values 0.0082 0.0064 0
[110]
SNU475 FGF3
Mean 0.00717
Standard deviation 0.003
Values 0.0093 0.0051
[111]
THLE FGF3
Mean 0
Standard deviation 0
Values 0 0
[112]
liver FGF3
Mean 0
Standard deviation 0
Values 0 0 0 0