REACTOME_FATTY_ACIDS_BOUND_TO_GPR40_FFAR1_REGULATE_INSULIN_SECRETION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 GNA11 Guanine nucleotide-binding protein subunit alpha-11 [1] -1.18[2] -1.93[3] -1.81[4] -1.76[5] -1.10[6] -1.76[7]
2 GNAQ Guanine nucleotide-binding protein G(q) subunit alpha [8] -0.44[9] -0.33[10] 0.35[11] 1.02[12] 1.09[13] 0.93[14]
3 PLCB3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [15] 1.49[16] 0.30[17] 0.93[18] 2.14[19] 1.64[20] 0.22[21]
4 PLCB1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [22] 2.28[23] 3.23[24] 2.82[25] 0.21[26] 0.55[27] 1.98[28]
5 PLCB2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [29] -2.14[30] -7.59[31] -9.26[32] -2.51[33] -3.36[34] 1.73[35]
6 GNA15 Guanine nucleotide-binding protein subunit alpha-15 [36] -3.90[37] -6.28[38] [39] -6.60[40] -3.19[41] -0.41[42]
7 GNA14 Guanine nucleotide-binding protein subunit alpha-14 [43] -6.57[44] -7.64[45] -6.32[46] -6.86[47] -3.91[48] 2.73[49]
8 FFAR1 Free fatty acid receptor 1 [50] [51] [52] [53] [54] [55] [56]
[1]
ref_hepatocyte GNA11
Mean 10
Standard deviation 6.7
Values 19 12 12 3.8 2.8
[2]
HepG2 GNA11
Mean 14
Standard deviation 0.12
Values 14 14
[3]
HepG2.C3A GNA11
Mean 11.8
Standard deviation 0.77
Values 11 12
[4]
HuH.7 GNA11
Mean 10.9
Standard deviation 2.1
Values 13 11 8.6
[5]
SNU475 GNA11
Mean 8.12
Standard deviation 0.83
Values 8.7 7.5
[6]
THLE GNA11
Mean 15.8
Standard deviation 3.1
Values 14 18
[7]
liver GNA11
Mean 5.97
Standard deviation 1.7
Values 6.1 7 3.6 7.3
[8]
ref_hepatocyte GNAQ
Mean 1.88
Standard deviation 1
Values 1.6 2 3.6 1.1 1.1
[9]
HepG2 GNAQ
Mean 4.36
Standard deviation 1.2
Values 3.5 5.2
[10]
HepG2.C3A GNAQ
Mean 6.67
Standard deviation 0.93
Values 6 7.3
[11]
HuH.7 GNAQ
Mean 9.12
Standard deviation 3.7
Values 11 11 4.8
[12]
SNU475 GNAQ
Mean 10.4
Standard deviation 1.4
Values 11 9.4
[13]
THLE GNAQ
Mean 13.5
Standard deviation 3.4
Values 11 16
[14]
liver GNAQ
Mean 7.23
Standard deviation 3.8
Values 5.1 11 3 9.6
[15]
ref_hepatocyte PLCB3
Mean 1.72
Standard deviation 1
Values 3.3 2 1.6 0.84 0.87
[16]
HepG2 PLCB3
Mean 15.2
Standard deviation 2.5
Values 13 17
[17]
HepG2.C3A PLCB3
Mean 9.48
Standard deviation 0.28
Values 9.3 9.7
[18]
HuH.7 PLCB3
Mean 12.5
Standard deviation 4.9
Values 15 6.9 16
[19]
SNU475 PLCB3
Mean 20.7
Standard deviation 4.4
Values 24 18
[20]
THLE PLCB3
Mean 18.1
Standard deviation 1.4
Values 17 19
[21]
liver PLCB3
Mean 4.04
Standard deviation 2.9
Values 1.7 5.4 1.5 7.5
[22]
ref_hepatocyte PLCB1
Mean 0.993
Standard deviation 1.3
Values 3.2 0.71 0.37 0.15 0.52
[23]
HepG2 PLCB1
Mean 15.2
Standard deviation 2.6
Values 13 17
[24]
HepG2.C3A PLCB1
Mean 41.8
Standard deviation 4.5
Values 45 39
[25]
HuH.7 PLCB1
Mean 26.9
Standard deviation 8.9
Values 26 36 19
[26]
SNU475 PLCB1
Mean 3.13
Standard deviation 0.39
Values 3.4 2.9
[27]
THLE PLCB1
Mean 4.93
Standard deviation 0.69
Values 5.4 4.4
[28]
liver PLCB1
Mean 7.93
Standard deviation 2.5
Values 8.6 11 6 6
[29]
ref_hepatocyte PLCB2
Mean 0.44
Standard deviation 0.47
Values 0 0.049 0.42 0.57 1.2
[30]
HepG2 PLCB2
Mean 0.316
Standard deviation 0.31
Values 0.53 0.099
[31]
HepG2.C3A PLCB2
Mean 0.0102
Standard deviation 0.00071
Values 0.0097 0.011
[32]
HuH.7 PLCB2
Mean 0.00273
Standard deviation 0.0047
Values 0.0082 0 0
[33]
SNU475 PLCB2
Mean 0.211
Standard deviation 0.062
Values 0.26 0.17
[34]
THLE PLCB2
Mean 0.145
Standard deviation 0.029
Values 0.12 0.16
[35]
liver PLCB2
Mean 2.94
Standard deviation 1.6
Values 1.8 3.5 1.5 4.9
[36]
ref_hepatocyte GNA15
Mean 0.271
Standard deviation 0.31
Values 0 0 0.27 0.33 0.76
[37]
HepG2 GNA15
Mean 0.0573
Standard deviation 0.081
Values 0.11 0
[38]
HepG2.C3A GNA15
Mean 0.0156
Standard deviation 0.0083
Values 0.0097 0.021
[39]
HuH.7 GNA15
Mean 0
Standard deviation 0
Values 0 0 0
[40]
SNU475 GNA15
Mean 0.0076
Standard deviation 0.011
Values 0 0.015
[41]
THLE GNA15
Mean 0.101
Standard deviation 0.0083
Values 0.095 0.11
[42]
liver GNA15
Mean 0.411
Standard deviation 0.3
Values 0.047 0.6 0.28 0.71
[43]
ref_hepatocyte GNA14
Mean 0.216
Standard deviation 0.25
Values 0 0.19 0 0.28 0.61
[44]
HepG2 GNA14
Mean 0.00716
Standard deviation 0.002
Values 0.0057 0.0086
[45]
HepG2.C3A GNA14
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[46]
HuH.7 GNA14
Mean 0.0103
Standard deviation 0.013
Values 0.025 0.0064 0
[47]
SNU475 GNA14
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[48]
THLE GNA14
Mean 0.0485
Standard deviation 0.023
Values 0.065 0.032
[49]
liver GNA14
Mean 2.89
Standard deviation 0.64
Values 3.5 2.1 3.3 2.7
[50]
ref_hepatocyte FFAR1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[51]
HepG2 FFAR1
Mean 0.0086
Standard deviation 0.012
Values 0.017 0
[52]
HepG2.C3A FFAR1
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[53]
HuH.7 FFAR1
Mean 0
Standard deviation 0
Values 0 0 0
[54]
SNU475 FFAR1
Mean 0
Standard deviation 0
Values 0 0
[55]
THLE FFAR1
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[56]
liver FFAR1
Mean 0
Standard deviation 0
Values 0 0 0 0