REACTOME_FANCONI_ANEMIA_PATHWAY			Return to index
Order	Gene	Description	ref_hepatocyte	HepG2	HepG2.C3A	HuH.7	SNU475	THLE	liver
1	UBB	Polyubiquitin-B	[1]	-0.36[2]	-0.66[3]	-0.79[4]	-0.71[5]	-0.54[6]	-0.04[7]
2	RPS27A	Ubiquitin-40S ribosomal protein S27a	[8]	[9]	[10]	[11]	[12]	[13]	[14]
3	UBC	Polyubiquitin-C	[15]	0.09[16]	0.09[17]	-0.43[18]	0.14[19]	-0.16[20]	0.41[21]
4	UBA52	Ubiquitin-60S ribosomal protein L40	[22]	2.52[23]	2.32[24]	3.08[25]	1.54[26]	2.07[27]	1.18[28]
5	RPA2	Replication protein A 32 kDa subunit	[29]	0.38[30]	0.35[31]	0.63[32]	1.32[33]	1.12[34]	-0.56[35]
6	ERCC1	DNA excision repair protein ERCC-1	[36]	1.35[37]	1.10[38]	0.98[39]	1.41[40]	1.55[41]	0.77[42]
7	SLX1B		[43]	[44]	[45]	[46]	[47]	[48]	[49]
8	SLX1A	Structure-specific endonuclease subunit SLX1	[50]	[51]	[52]	[53]	[54]	[55]	[56]
9	RPA1	Replication protein A 70 kDa DNA-binding subunit	[57]	3.15[58]	2.78[59]	2.78[60]	3.92[61]	3.65[62]	1.84[63]
10	RPA3	Replication protein A 14 kDa subunit	[64]	1.47[65]	2.17[66]	2.61[67]	1.16[68]	1.16[69]	1.15[70]
11	MUS81	Crossover junction endonuclease MUS81	[71]	1.63[72]	1.74[73]	1.20[74]	2.47[75]	1.92[76]	1.27[77]
12	USP1	Ubiquitin carboxyl-terminal hydrolase 1	[78]	2.38[79]	3.66[80]	3.50[81]	3.84[82]	3.92[83]	2.17[84]
13	UBE2T	Ubiquitin-conjugating enzyme E2 T	[85]	2.68[86]	3.18[87]	3.01[88]	3.39[89]	3.51[90]	-0.79[91]
14	WDR48	WD repeat-containing protein 48	[92]	2.89[93]	3.64[94]	3.56[95]	2.56[96]	2.87[97]	3.06[98]
15	FANCL	E3 ubiquitin-protein ligase FANCL	[99]	0.87[100]	2.74[101]	1.37[102]	1.72[103]	1.56[104]	1.74[105]
16	FAN1	Fanconi-associated nuclease 1	[106]	2.85[107]	3.03[108]	2.58[109]	3.60[110]	3.40[111]	3.92[112]
17	FANCA	Fanconi anemia group A protein	[113]	3.51[114]	4.08[115]	3.52[116]	3.38[117]	3.44[118]	1.48[119]
18	FANCF	Fanconi anemia group F protein	[120]	2.84[121]	2.47[122]	3.38[123]	2.89[124]	1.37[125]	3.05[126]
19	FANCI	Fanconi anemia group I protein	[127]	4.27[128]	4.60[129]	4.82[130]	5.41[131]	5.43[132]	1.67[133]
20	FANCC	Fanconi anemia group C protein	[134]	2.86[135]	3.08[136]	1.19[137]	3.61[138]	3.49[139]	4.76[140]
21	DCLRE1A	DNA cross-link repair 1A protein	[141]	2.60[142]	4.45[143]	3.78[144]	3.22[145]	3.29[146]	3.48[147]
22	ATRIP	ATR-interacting protein	[148]	2.09[149]	2.22[150]	2.82[151]	1.72[152]	2.52[153]	1.67[154]
23	ATR	Serine/threonine-protein kinase ATR	[155]	2.94[156]	3.83[157]	3.63[158]	4.60[159]	4.27[160]	5.39[161]
24	FANCE	Fanconi anemia group E protein	[162]	2.63[163]	2.83[164]	2.40[165]	2.88[166]	2.59[167]	-0.74[168]
25	DCLRE1B	5' exonuclease Apollo	[169]	2.92[170]	2.81[171]	2.92[172]	3.58[173]	3.58[174]	1.18[175]
26	FANCG	Fanconi anemia group G protein	[176]	3.81[177]	4.51[178]	5.02[179]	3.78[180]	4.38[181]	1.72[182]
27	FANCD2	Fanconi anemia group D2 protein	[183]	4.27[184]	4.31[185]	5.10[186]	4.48[187]	4.89[188]	1.86[189]
28	ERCC4	DNA repair endonuclease XPF	[190]	4.05[191]	3.63[192]	3.52[193]	4.29[194]	4.16[195]	4.25[196]
29	EME1	Crossover junction endonuclease EME1	[197]	4.41[198]	4.94[199]	5.45[200]	4.94[201]	4.55[202]	0.35[203]
30	FANCM	Fanconi anemia group M protein	[204]	2.71[205]	4.80[206]	5.03[207]	5.04[208]	4.83[209]	4.54[210]
31	SLX4	Structure-specific endonuclease subunit SLX4	[211]	4.75[212]	4.82[213]	5.09[214]	5.16[215]	5.11[216]	4.10[217]
32	EME2	Probable crossover junction endonuclease EME2	[218]	3.59[219]	4.01[220]	3.19[221]	3.41[222]	3.39[223]	4.65[224]
33	FANCB	Fanconi anemia group B protein	[225]	4.09[226]	4.54[227]	5.48[228]	6.17[229]	5.84[230]	3.05[231]
34	POLN	DNA polymerase nu	[232]	0.88[233]	2.78[234]	4.79[235]	4.77[236]	3.67[237]	4.63[238]
35	CENPX	Centromere protein X	[239]	[240]	[241]	[242]	[243]	[244]	[245]
36	FAAP100	Fanconi anemia core complex-associated protein 100	[246]	[247]	[248]	[249]	[250]	[251]	[252]
37	FAAP20	Fanconi anemia core complex-associated protein 20	[253]	[254]	[255]	[256]	[257]	[258]	[259]
38	CENPS	Centromere protein S	[260]	[261]	[262]	[263]	[264]	[265]	[266]
39	FAAP24	Fanconi anemia core complex-associated protein 24	[267]	[268]	[269]	[270]	[271]	[272]	[273]