REACTOME_EXTRA_NUCLEAR_ESTROGEN_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 HSP90AA1 Heat shock protein HSP 90-alpha [1] -0.47[2] 0.36[3] -0.24[4] -0.25[5] -0.23[6] -0.78[7]
2 HSPB1 Heat shock protein beta-1 [8] -3.32[9] -4.28[10] -3.35[11] -1.73[12] -3.57[13] -3.33[14]
3 GNG5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 -1.03[15] -1.00[16] -1.69[17] -2.15[18] -2.08[19] -1.11[20]
4 GNB1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 [21] 1.19[22] 1.06[23] 0.76[24] 0.94[25] 1.07[26] -0.76[27]
5 PRMT1 Protein arginine N-methyltransferase 1 [28] 0.42[29] 0.32[30] 0.97[31] -1.42[32] -0.96[33] -1.47[34]
6 FOS Proto-oncogene c-Fos [35] -5.84[36] -4.72[37] -5.21[38] -6.51[39] -5.11[40] -0.83[41]
7 GNB2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 [42] -0.43[43] -0.82[44] -0.31[45] -0.71[46] -0.32[47] -1.13[48]
8 AKT1 RAC-alpha serine/threonine-protein kinase [49] 0.26[50] -0.12[51] -1.03[52] -0.39[53] -0.04[54] 0.23[55]
9 GNG10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 -4.53[56] -4.38[57] -4.51[58] -4.15[59] -3.00[60] -3.87[61]
10 GNAI2 Guanine nucleotide-binding protein G(i) subunit alpha-2 [62] 0.24[63] -0.96[64] -0.63[65] -0.51[66] 0.89[67] 0.28[68]
11 CALM1 Calmodulin-1 [69] 0.25[70] 0.14[71] 0.78[72] 1.24[73] 0.85[74] 2.09[75]
12 CCND1 G1/S-specific cyclin-D1 [76] 3.23[77] 0.58[78] 1.58[79] 1.54[80] 0.40[81] 1.53[82]
13 CAV1 Caveolin-1 [83] -6.66[84] -9.63[85] -3.18[86] 1.04[87] 0.02[88] -1.52[89]
14 SHC1 SHC-transforming protein 1 [90] 1.34[91] 1.41[92] 1.66[93] 2.31[94] 2.13[95] 1.25[96]
15 GNG12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 -4.58[97] -7.65[98] 0.47[99] 1.54[100] 1.97[101] 0.96[102]
16 GNAI3 Guanine nucleotide-binding protein G(k) subunit alpha [103] 0.30[104] 0.70[105] 0.97[106] 0.76[107] 0.73[108] 0.71[109]
17 NRAS GTPase NRas [110] 0.80[111] 1.09[112] 1.68[113] 0.66[114] 0.56[115] 0.22[116]
18 CDKN1B Cyclin-dependent kinase inhibitor 1B [117] 0.09[118] 0.39[119] 0.76[120] -1.45[121] -0.65[122] -0.43[123]
19 XPO1 Exportin-1 [124] 1.53[125] 2.10[126] 2.31[127] 1.79[128] 2.21[129] 1.33[130]
20 HRAS GTPase HRas [131] -0.83[132] -1.68[133] -2.30[134] -1.29[135] -1.17[136] -2.19[137]
21 SPHK1 Sphingosine kinase 1 [138] 1.75[139] 2.30[140] -0.02[141] -2.54[142] 0.06[143] -4.53[144]
22 CAV2 Caveolin-2 [145] -4.83[146] -7.05[147] -1.47[148] 0.46[149] -0.50[150] 0.96[151]
23 MAPK1 Mitogen-activated protein kinase 1 [152] 1.88[153] 1.88[154] 1.88[155] 1.51[156] 1.49[157] 2.25[158]
24 AKT2 RAC-beta serine/threonine-protein kinase [159] 1.13[160] 1.27[161] 1.57[162] 0.52[163] 0.64[164] 1.60[165]
25 MMP3 Stromelysin-1 [166] -4.34[167] -9.40[168] -11.60[169] -2.08[170] -4.81[171] -7.85[172]
26 KRAS GTPase KRas [173] -0.34[174] -0.50[175] 1.27[176] 0.46[177] 0.45[178] 1.15[179]
27 PTK2 Focal adhesion kinase 1 [180] 0.91[181] 1.25[182] 1.81[183] 1.61[184] 1.14[185] 1.23[186]
28 PRKCZ Protein kinase C zeta type [187] 0.65[188] 0.88[189] -0.94[190] -2.64[191] -4.51[192] -1.17[193]
29 PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha [194] -0.30[195] -0.32[196] 0.94[197] 1.73[198] 1.56[199] 3.48[200]
30 UHMK1 Serine/threonine-protein kinase Kist [201] 1.38[202] 1.34[203] 1.98[204] 2.62[205] 2.59[206] 3.60[207]
31 ELK1 ETS domain-containing protein Elk-1 [208] -0.14[209] -2.42[210] 0.17[211] -0.07[212] 0.85[213] 0.31[214]
32 GNAI1 Guanine nucleotide-binding protein G(i) subunit alpha-1 [215] -1.47[216] -2.56[217] -0.24[218] 0.87[219] 0.58[220] 1.31[221]
33 SRF Serum response factor [222] 1.64[223] 1.06[224] 0.50[225] 1.20[226] 0.62[227] -0.31[228]
34 ZDHHC7 Palmitoyltransferase ZDHHC7 [229] 2.03[230] 1.71[231] 1.48[232] 1.30[233] 1.24[234] 0.18[235]
35 EGFR Epidermal growth factor receptor [236] -0.52[237] -1.04[238] 2.02[239] 0.09[240] 1.04[241] 3.13[242]
36 PIK3R2 Phosphatidylinositol 3-kinase regulatory subunit beta [243] 2.05[244] 2.13[245] 2.91[246] 0.37[247] 1.26[248] 0.18[249]
37 AREG Amphiregulin [250] -2.69[251] -6.07[252] -7.66[253] -10.04[254] 0.60[255] -9.83[256]
38 GNB5 Guanine nucleotide-binding protein subunit beta-5 [257] 0.27[258] 0.17[259] 1.36[260] 0.45[261] 0.90[262] 1.36[263]
39 MAPK3 Mitogen-activated protein kinase 3 [264] 2.03[265] 1.93[266] 2.14[267] 0.08[268] 0.44[269] -0.57[270]
40 SRC Proto-oncogene tyrosine-protein kinase Src [271] 3.20[272] 3.04[273] 2.21[274] 2.06[275] 1.57[276] -0.38[277]
41 PDPK1 3-phosphoinositide-dependent protein kinase 1 [278] 2.51[279] 3.55[280] 2.44[281] 1.10[282] 1.82[283] 2.98[284]
42 FOXO3 Forkhead box protein O3 [285] 0.63[286] 0.57[287] 1.39[288] 0.06[289] 1.63[290] 2.81[291]
43 TGFA Protransforming growth factor alpha [292] 1.97[293] 2.89[294] -7.99[295] -1.30[296] -2.19[297] 0.08[298]
44 PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform -0.20[299] 1.29[300] 1.65[301] 0.79[302] 1.33[303] 2.39[304]
45 HBEGF Proheparin-binding EGF-like growth factor [305] -0.81[306] -1.77[307] -2.66[308] -0.04[309] -0.02[310] -1.96[311]
46 CREB1 Cyclic AMP-responsive element-binding protein 1 [312] 1.90[313] 2.91[314] 3.57[315] 2.20[316] 2.48[317] 2.82[318]
47 ESR1 Estrogen receptor [319] -7.13[320] [321] -5.58[322] -4.51[323] -6.44[324] 2.87[325]
48 GNG11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 -8.01[326] -8.15[327] -7.28[328] 1.92[329] 3.58[330] 2.71[331]
49 STRN Striatin [332] 2.14[333] 2.96[334] 2.76[335] 2.98[336] 3.21[337] 3.37[338]
50 GNG7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 1.73[339] 1.24[340] 2.22[341] -2.58[342] -1.62[343] 0.50[344]
51 BTC Probetacellulin [345] -7.97[346] -8.50[347] -4.10[348] -3.21[349] -2.91[350] -2.44[351]
52 MMP9 Matrix metalloproteinase-9 [352] -2.54[353] -3.74[354] -5.96[355] -1.77[356] -4.00[357] 0.33[358]
53 IGF1R Insulin-like growth factor 1 receptor [359] 4.92[360] 4.08[361] 2.93[362] 4.13[363] 4.01[364] 2.56[365]
54 GNG4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 3.64[366] 1.27[367] 5.24[368] 0.92[369] -0.87[370] -2.08[371]
55 ZDHHC21 Palmitoyltransferase ZDHHC21 [372] 2.04[373] 2.75[374] -2.28[375] 2.95[376] 2.73[377] 4.49[378]
56 PIK3R3 Phosphatidylinositol 3-kinase regulatory subunit gamma [379] 1.90[380] 1.76[381] 2.78[382] 2.83[383] 2.18[384] 3.15[385]
57 GNB4 Guanine nucleotide-binding protein subunit beta-4 [386] -0.19[387] 0.15[388] 1.33[389] 2.34[390] 5.41[391] 4.56[392]
58 AKT3 RAC-gamma serine/threonine-protein kinase [393] -1.67[394] -4.37[395] -3.51[396] 5.50[397] 4.79[398] 4.08[399]
59 S1PR3 Sphingosine 1-phosphate receptor 3 [400] -1.73[401] -2.94[402] -1.32[403] 4.15[404] 5.51[405] 2.84[406]
60 GNG2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 -6.10[407] -7.13[408] [409] 2.78[410] 2.58[411] 3.25[412]
61 NOS3 Nitric oxide synthase, endothelial [413] 4.94[414] 1.90[415] 1.54[416] -0.28[417] 1.39[418] 3.25[419]
62 EREG Proepiregulin [420] 1.93[421] 1.71[422] -2.53[423] -1.91[424] 3.68[425] -1.00[426]
63 MMP7 Matrilysin [427] 0.60[428] -2.33[429] [430] 2.21[431] -2.72[432] 1.19[433]
64 MMP2 72 kDa type IV collagenase [434] 3.61[435] -3.52[436] -2.07[437] 7.10[438] 6.98[439] 4.41[440]
65 GNGT2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 [441] [442] [443] -2.41[444] -6.75[445] 0.58[446]
66 GNG3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 -0.68[447] 1.01[448] -1.05[449] -1.04[450] -1.02[451] 0.39[452]
67 BCL2 Apoptosis regulator Bcl-2 [453] -2.68[454] 2.58[455] -4.65[456] 1.43[457] 1.48[458] 3.70[459]
68 GNB3 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 [460] 1.76[461] 3.87[462] 3.35[463] 0.67[464] 3.71[465] -1.21[466]
69 ESR2 Estrogen receptor beta [467] -0.39[468] -0.16[469] 0.04[470] 0.29[471] 0.72[472] 3.00[473]
70 EGF Pro-epidermal growth factor [474] 2.14[475] 3.79[476] 7.57[477] 8.68[478] 6.44[479] 2.05[480]
71 GNG13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 [481] [482] [483] [484] [485] [486]
72 EPGN Epigen [487] [488] [489] [490] [491] [492] [493]
73 GNGT1 Guanine nucleotide-binding protein G(T) subunit gamma-T1 [494] [495] [496] [497] [498] [499] [500]
74 GNG8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 [501] [502] [503] [504] [505] [506]
75 GNAT3 Guanine nucleotide-binding protein G(t) subunit alpha-3 [507] [508] [509] [510] [511] [512] [513]
[1]
ref_hepatocyte HSP90AA1
Mean 356
Standard deviation 2.5e+02
Values 5.4e+02 6.9e+02 1.3e+02 2.5e+02 1.7e+02
[2]
HepG2 HSP90AA1
Mean 503
Standard deviation 2.6e+02
Values 3.2e+02 6.9e+02
[3]
HepG2.C3A HSP90AA1
Mean 878
Standard deviation 5.2e+02
Values 5.1e+02 1.2e+03
[4]
HuH.7 HSP90AA1
Mean 494
Standard deviation 76
Values 5.4e+02 4.1e+02 5.4e+02
[5]
SNU475 HSP90AA1
Mean 696
Standard deviation 1.5e+02
Values 5.9e+02 8e+02
[6]
THLE HSP90AA1
Mean 627
Standard deviation 16
Values 6.4e+02 6.2e+02
[7]
liver HSP90AA1
Mean 212
Standard deviation 50
Values 2.7e+02 1.9e+02 2.4e+02 1.6e+02
[8]
ref_hepatocyte HSPB1
Mean 337
Standard deviation 2.6e+02
Values 23 4.5e+02 7.1e+02 2.1e+02 2.9e+02
[9]
HepG2 HSPB1
Mean 66.2
Standard deviation 12
Values 74 58
[10]
HepG2.C3A HSPB1
Mean 33.5
Standard deviation 7.2
Values 39 28
[11]
HuH.7 HSPB1
Mean 54.1
Standard deviation 6.5
Values 51 50 62
[12]
SNU475 HSPB1
Mean 236
Standard deviation 31
Values 2.6e+02 2.1e+02
[13]
THLE HSPB1
Mean 58.7
Standard deviation 5.3
Values 55 62
[14]
liver HSPB1
Mean 34.3
Standard deviation 37
Values 73 2 59 3.3
[15]
ref_hepatocyte GNG5
Mean 71
Standard deviation 24
Values 60 35 85 91 85
[16]
HepG2 GNG5
Mean 68.1
Standard deviation 11
Values 60 76
[17]
HepG2.C3A GNG5
Mean 68.6
Standard deviation 10
Values 61 76
[18]
HuH.7 GNG5
Mean 36.1
Standard deviation 6.8
Values 38 28 42
[19]
SNU475 GNG5
Mean 37.2
Standard deviation 3.1
Values 39 35
[20]
THLE GNG5
Mean 34.8
Standard deviation 0.49
Values 34 35
[21]
liver GNG5
Mean 33.6
Standard deviation 38
Values 75 1.4 56 1.4
[22]
ref_hepatocyte GNB1
Mean 42.7
Standard deviation 15
Values 44 60 53 31 24
[23]
HepG2 GNB1
Mean 190
Standard deviation 15
Values 2e+02 1.8e+02
[24]
HepG2.C3A GNB1
Mean 171
Standard deviation 4.5
Values 1.7e+02 1.7e+02
[25]
HuH.7 GNB1
Mean 118
Standard deviation 23
Values 1.4e+02 93 1.2e+02
[26]
SNU475 GNB1
Mean 191
Standard deviation 19
Values 2e+02 1.8e+02
[27]
THLE GNB1
Mean 185
Standard deviation 12
Values 1.8e+02 1.9e+02
[28]
liver GNB1
Mean 25.7
Standard deviation 5
Values 31 25 19 27
[29]
ref_hepatocyte PRMT1
Mean 40.1
Standard deviation 17
Values 45 56 53 32 15
[30]
HepG2 PRMT1
Mean 105
Standard deviation 22
Values 1.2e+02 90
[31]
HepG2.C3A PRMT1
Mean 96.5
Standard deviation 1.5
Values 98 95
[32]
HuH.7 PRMT1
Mean 128
Standard deviation 40
Values 1.4e+02 83 1.6e+02
[33]
SNU475 PRMT1
Mean 34.9
Standard deviation 0.11
Values 35 35
[34]
THLE PRMT1
Mean 42.7
Standard deviation 5.5
Values 39 47
[35]
liver PRMT1
Mean 14.8
Standard deviation 4.4
Values 19 11 18 11
[36]
ref_hepatocyte FOS
Mean 40
Standard deviation 67
Values 4 0.65 9 1.6e+02 27
[37]
HepG2 FOS
Mean 1.37
Standard deviation 1
Values 2.1 0.66
[38]
HepG2.C3A FOS
Mean 2.92
Standard deviation 1.9
Values 4.3 1.6
[39]
HuH.7 FOS
Mean 1.77
Standard deviation 0.38
Values 1.5 1.6 2.2
[40]
SNU475 FOS
Mean 1.02
Standard deviation 0.13
Values 0.93 1.1
[41]
THLE FOS
Mean 2.4
Standard deviation 0.3
Values 2.2 2.6
[42]
liver FOS
Mean 23
Standard deviation 32
Values 71 4.8 10 5.7
[43]
ref_hepatocyte GNB2
Mean 38.8
Standard deviation 20
Values 15 25 41 67 46
[44]
HepG2 GNB2
Mean 56.5
Standard deviation 6.2
Values 61 52
[45]
HepG2.C3A GNB2
Mean 42.3
Standard deviation 7.9
Values 48 37
[46]
HuH.7 GNB2
Mean 51.2
Standard deviation 3.5
Values 50 49 55
[47]
SNU475 GNB2
Mean 55.4
Standard deviation 5.7
Values 59 51
[48]
THLE GNB2
Mean 64.6
Standard deviation 5.2
Values 61 68
[49]
liver GNB2
Mean 18.2
Standard deviation 7.1
Values 24 11 25 13
[50]
ref_hepatocyte AKT1
Mean 37.6
Standard deviation 15
Values 55 50 19 31 32
[51]
HepG2 AKT1
Mean 87.8
Standard deviation 2.3
Values 89 86
[52]
HepG2.C3A AKT1
Mean 66.6
Standard deviation 2.4
Values 65 68
[53]
HuH.7 AKT1
Mean 30.2
Standard deviation 6.6
Values 33 23 35
[54]
SNU475 AKT1
Mean 66.6
Standard deviation 14
Values 76 57
[55]
THLE AKT1
Mean 75.8
Standard deviation 6.1
Values 72 80
[56]
liver AKT1
Mean 45.1
Standard deviation 25
Values 34 48 20 79
[57]
ref_hepatocyte GNG10
Mean 36.1
Standard deviation 25
Values 54 68 12 12 34
[58]
HepG2 GNG10
Mean 3.07
Standard deviation 0.45
Values 2.8 3.4
[59]
HepG2.C3A GNG10
Mean 3.33
Standard deviation 1.3
Values 2.4 4.3
[60]
HuH.7 GNG10
Mean 2.59
Standard deviation 0.11
Values 2.6 2.5 2.7
[61]
SNU475 GNG10
Mean 4.73
Standard deviation 1.4
Values 5.8 3.7
[62]
THLE GNG10
Mean 9.34
Standard deviation 0.66
Values 8.9 9.8
[63]
liver GNG10
Mean 2.53
Standard deviation 1.2
Values 3.6 2.1 3.3 1.1
[64]
ref_hepatocyte GNAI2
Mean 32.9
Standard deviation 13
Values 10 31 41 40 42
[65]
HepG2 GNAI2
Mean 76.1
Standard deviation 11
Values 68 84
[66]
HepG2.C3A GNAI2
Mean 32.5
Standard deviation 8.6
Values 26 39
[67]
HuH.7 GNAI2
Mean 34.9
Standard deviation 7.6
Values 41 26 37
[68]
SNU475 GNAI2
Mean 53.7
Standard deviation 11
Values 62 46
[69]
THLE GNAI2
Mean 126
Standard deviation 19
Values 1.1e+02 1.4e+02
[70]
liver GNAI2
Mean 40.9
Standard deviation 20
Values 61 27 54 21
[71]
ref_hepatocyte CALM1
Mean 29.2
Standard deviation 11
Values 17 40 21 28 40
[72]
HepG2 CALM1
Mean 67.9
Standard deviation 4.3
Values 65 71
[73]
HepG2.C3A CALM1
Mean 62
Standard deviation 16
Values 51 73
[74]
HuH.7 CALM1
Mean 81.9
Standard deviation 15
Values 90 64 92
[75]
SNU475 CALM1
Mean 160
Standard deviation 24
Values 1.8e+02 1.4e+02
[76]
THLE CALM1
Mean 109
Standard deviation 13
Values 1e+02 1.2e+02
[77]
liver CALM1
Mean 127
Standard deviation 70
Values 2.1e+02 80 1.7e+02 57
[78]
ref_hepatocyte CCND1
Mean 23
Standard deviation 14
Values 44 28 19 11 12
[79]
HepG2 CCND1
Mean 421
Standard deviation 48
Values 4.5e+02 3.9e+02
[80]
HepG2.C3A CCND1
Mean 66.1
Standard deviation 12
Values 58 74
[81]
HuH.7 CCND1
Mean 113
Standard deviation 31
Values 1.4e+02 79 1.2e+02
[82]
SNU475 CCND1
Mean 155
Standard deviation 66
Values 1.1e+02 2e+02
[83]
THLE CCND1
Mean 62.5
Standard deviation 6.4
Values 67 58
[84]
liver CCND1
Mean 67.8
Standard deviation 49
Values 26 1.1e+02 1.1e+02 25
[85]
ref_hepatocyte CAV1
Mean 22.6
Standard deviation 36
Values 0 84 28 0.35 0.99
[86]
HepG2 CAV1
Mean 0.438
Standard deviation 0.44
Values 0.75 0.12
[87]
HepG2.C3A CAV1
Mean 0.055
Standard deviation 0.032
Values 0.078 0.032
[88]
HuH.7 CAV1
Mean 4.08
Standard deviation 1.9
Values 3.5 6.2 2.5
[89]
SNU475 CAV1
Mean 108
Standard deviation 15
Values 1.2e+02 98
[90]
THLE CAV1
Mean 47.4
Standard deviation 15
Values 37 58
[91]
liver CAV1
Mean 8.05
Standard deviation 2.9
Values 7.6 8.2 12 4.7
[92]
ref_hepatocyte SHC1
Mean 16.6
Standard deviation 7.2
Values 5.8 17 19 26 16
[93]
HepG2 SHC1
Mean 82
Standard deviation 0.099
Values 82 82
[94]
HepG2.C3A SHC1
Mean 84.9
Standard deviation 11
Values 77 93
[95]
HuH.7 SHC1
Mean 85.9
Standard deviation 2.4
Values 89 84 85
[96]
SNU475 SHC1
Mean 191
Standard deviation 36
Values 2.2e+02 1.7e+02
[97]
THLE SHC1
Mean 150
Standard deviation 11
Values 1.4e+02 1.6e+02
[98]
liver SHC1
Mean 40.4
Standard deviation 11
Values 37 32 56 37
[99]
ref_hepatocyte GNG12
Mean 16.5
Standard deviation 18
Values 0.58 46 23 5.6 7.3
[100]
HepG2 GNG12
Mean 1.35
Standard deviation 0.72
Values 1.9 0.84
[101]
HepG2.C3A GNG12
Mean 0.158
Standard deviation 0.011
Values 0.17 0.15
[102]
HuH.7 GNG12
Mean 37.3
Standard deviation 6.6
Values 44 36 31
[103]
SNU475 GNG12
Mean 111
Standard deviation 32
Values 1.3e+02 89
[104]
THLE GNG12
Mean 133
Standard deviation 28
Values 1.1e+02 1.5e+02
[105]
liver GNG12
Mean 32.7
Standard deviation 9.9
Values 36 32 43 19
[106]
ref_hepatocyte GNAI3
Mean 15.6
Standard deviation 11
Values 15 35 11 6.9 10
[107]
HepG2 GNAI3
Mean 37.5
Standard deviation 8.9
Values 31 44
[108]
HepG2.C3A GNAI3
Mean 48.7
Standard deviation 8.6
Values 43 55
[109]
HuH.7 GNAI3
Mean 50
Standard deviation 3.6
Values 54 47 49
[110]
SNU475 GNAI3
Mean 61.5
Standard deviation 5.4
Values 65 58
[111]
THLE GNAI3
Mean 53.3
Standard deviation 7.7
Values 48 59
[112]
liver GNAI3
Mean 26
Standard deviation 3.5
Values 26 25 31 23
[113]
ref_hepatocyte NRAS
Mean 14.4
Standard deviation 13
Values 32 23 9.3 3.3 4.6
[114]
HepG2 NRAS
Mean 49.3
Standard deviation 10
Values 42 57
[115]
HepG2.C3A NRAS
Mean 59.2
Standard deviation 18
Values 47 72
[116]
HuH.7 NRAS
Mean 75.6
Standard deviation 9.1
Values 86 70 71
[117]
SNU475 NRAS
Mean 52.9
Standard deviation 9.2
Values 59 46
[118]
THLE NRAS
Mean 44
Standard deviation 8.9
Values 38 50
[119]
liver NRAS
Mean 17.2
Standard deviation 2.6
Values 14 21 18 16
[120]
ref_hepatocyte CDKN1B
Mean 13.8
Standard deviation 6
Values 23 13 7.5 10 15
[121]
HepG2 CDKN1B
Mean 28.7
Standard deviation 3.4
Values 31 26
[122]
HepG2.C3A CDKN1B
Mean 34.7
Standard deviation 1.4
Values 34 36
[123]
HuH.7 CDKN1B
Mean 38.2
Standard deviation 3.7
Values 35 42 37
[124]
SNU475 CDKN1B
Mean 11.8
Standard deviation 2.9
Values 14 9.7
[125]
THLE CDKN1B
Mean 18.2
Standard deviation 3.4
Values 16 21
[126]
liver CDKN1B
Mean 10.5
Standard deviation 3.5
Values 9.9 14 5.8 12
[127]
ref_hepatocyte XPO1
Mean 13.2
Standard deviation 5.7
Values 20 19 8.6 8.1 11
[128]
HepG2 XPO1
Mean 74.7
Standard deviation 37
Values 48 1e+02
[129]
HepG2.C3A XPO1
Mean 109
Standard deviation 54
Values 71 1.5e+02
[130]
HuH.7 XPO1
Mean 107
Standard deviation 26
Values 1.3e+02 77 1.2e+02
[131]
SNU475 XPO1
Mean 106
Standard deviation 0.46
Values 1.1e+02 1.1e+02
[132]
THLE XPO1
Mean 127
Standard deviation 5.2
Values 1.2e+02 1.3e+02
[133]
liver XPO1
Mean 34
Standard deviation 14
Values 22 53 24 37
[134]
ref_hepatocyte HRAS
Mean 11.6
Standard deviation 9
Values 4 27 11 7.4 8.8
[135]
HepG2 HRAS
Mean 12.7
Standard deviation 1.1
Values 14 12
[136]
HepG2.C3A HRAS
Mean 6.96
Standard deviation 1.3
Values 6 7.9
[137]
HuH.7 HRAS
Mean 3.85
Standard deviation 1.6
Values 3.6 2.4 5.6
[138]
SNU475 HRAS
Mean 11
Standard deviation 0.62
Values 11 11
[139]
THLE HRAS
Mean 10.7
Standard deviation 2.3
Values 9.1 12
[140]
liver HRAS
Mean 2.6
Standard deviation 1.6
Values 4.1 1.1 3.8 1.4
[141]
ref_hepatocyte SPHK1
Mean 11.5
Standard deviation 14
Values 32 4.8 19 1.4 0.27
[142]
HepG2 SPHK1
Mean 75.9
Standard deviation 8.5
Values 82 70
[143]
HepG2.C3A SPHK1
Mean 109
Standard deviation 8.6
Values 1.2e+02 1e+02
[144]
HuH.7 SPHK1
Mean 18.7
Standard deviation 5.5
Values 19 13 24
[145]
SNU475 SPHK1
Mean 4.6
Standard deviation 3.4
Values 2.2 7
[146]
THLE SPHK1
Mean 24.9
Standard deviation 0.21
Values 25 25
[147]
liver SPHK1
Mean 0.512
Standard deviation 0.41
Values 1.1 0.3 0.18 0.46
[148]
ref_hepatocyte CAV2
Mean 11
Standard deviation 10
Values 0.41 24 19 3.7 7.1
[149]
HepG2 CAV2
Mean 0.756
Standard deviation 0.34
Values 1 0.51
[150]
HepG2.C3A CAV2
Mean 0.159
Standard deviation 0.033
Values 0.14 0.18
[151]
HuH.7 CAV2
Mean 6.47
Standard deviation 3.3
Values 4.9 10 4.3
[152]
SNU475 CAV2
Mean 35.1
Standard deviation 10
Values 42 28
[153]
THLE CAV2
Mean 16
Standard deviation 1.9
Values 15 17
[154]
liver CAV2
Mean 21.9
Standard deviation 11
Values 27 20 33 7.3
[155]
ref_hepatocyte MAPK1
Mean 10.7
Standard deviation 3.7
Values 14 13 13 6.1 7.4
[156]
HepG2 MAPK1
Mean 77.6
Standard deviation 22
Values 62 93
[157]
HepG2.C3A MAPK1
Mean 76.1
Standard deviation 7.2
Values 71 81
[158]
HuH.7 MAPK1
Mean 64.8
Standard deviation 7.4
Values 73 60 61
[159]
SNU475 MAPK1
Mean 71.1
Standard deviation 8
Values 77 65
[160]
THLE MAPK1
Mean 62.4
Standard deviation 14
Values 53 72
[161]
liver MAPK1
Mean 52.3
Standard deviation 14
Values 39 68 41 61
[162]
ref_hepatocyte AKT2
Mean 10.6
Standard deviation 2.8
Values 7.2 8.4 11 13 14
[163]
HepG2 AKT2
Mean 45.6
Standard deviation 3.3
Values 48 43
[164]
HepG2.C3A AKT2
Mean 49.1
Standard deviation 8.9
Values 55 43
[165]
HuH.7 AKT2
Mean 51.5
Standard deviation 9.8
Values 59 41 55
[166]
SNU475 AKT2
Mean 35.3
Standard deviation 5.9
Values 39 31
[167]
THLE AKT2
Mean 34.2
Standard deviation 3.5
Values 32 37
[168]
liver AKT2
Mean 33
Standard deviation 9.4
Values 24 36 27 45
[169]
ref_hepatocyte MMP3
Mean 9.23
Standard deviation 20
Values 0 0.19 45 1.1 0
[170]
HepG2 MMP3
Mean 0.894
Standard deviation 0.62
Values 1.3 0.46
[171]
HepG2.C3A MMP3
Mean 0.0263
Standard deviation 0.023
Values 0.0097 0.043
[172]
HuH.7 MMP3
Mean 0.00487
Standard deviation 0.0043
Values 0.0082 0.0064 0
[173]
SNU475 MMP3
Mean 5.06
Standard deviation 4.7
Values 1.8 8.4
[174]
THLE MMP3
Mean 0.682
Standard deviation 0.55
Values 0.29 1.1
[175]
liver MMP3
Mean 0.0408
Standard deviation 0.05
Values 0.024 0.11 0.026 0
[176]
ref_hepatocyte KRAS
Mean 8.97
Standard deviation 7.9
Values 18 17 5.4 1.7 2.7
[177]
HepG2 KRAS
Mean 13.9
Standard deviation 3.1
Values 12 16
[178]
HepG2.C3A KRAS
Mean 12.2
Standard deviation 2.3
Values 11 14
[179]
HuH.7 KRAS
Mean 35.4
Standard deviation 4.8
Values 40 30 36
[180]
SNU475 KRAS
Mean 28.7
Standard deviation 5.5
Values 33 25
[181]
THLE KRAS
Mean 25.4
Standard deviation 1.5
Values 24 26
[182]
liver KRAS
Mean 20.4
Standard deviation 8.7
Values 33 16 19 14
[183]
ref_hepatocyte PTK2
Mean 8.92
Standard deviation 4.8
Values 15 11 11 4.1 3.9
[184]
HepG2 PTK2
Mean 32.8
Standard deviation 5.2
Values 29 36
[185]
HepG2.C3A PTK2
Mean 40.9
Standard deviation 2.3
Values 43 39
[186]
HuH.7 PTK2
Mean 51.1
Standard deviation 2.8
Values 53 52 48
[187]
SNU475 PTK2
Mean 63.1
Standard deviation 3.5
Values 66 61
[188]
THLE PTK2
Mean 40.6
Standard deviation 3.7
Values 38 43
[189]
liver PTK2
Mean 21.5
Standard deviation 4.9
Values 19 27 16 24
[190]
ref_hepatocyte PRKCZ
Mean 7.98
Standard deviation 3.5
Values 14 4.6 6.7 8.2 6.6
[191]
HepG2 PRKCZ
Mean 24.4
Standard deviation 2
Values 26 23
[192]
HepG2.C3A PRKCZ
Mean 28.4
Standard deviation 7.3
Values 33 23
[193]
HuH.7 PRKCZ
Mean 6.79
Standard deviation 1.7
Values 6.1 8.8 5.5
[194]
SNU475 PRKCZ
Mean 2.98
Standard deviation 1.9
Values 4.4 1.6
[195]
THLE PRKCZ
Mean 0.727
Standard deviation 0.035
Values 0.75 0.7
[196]
liver PRKCZ
Mean 3.64
Standard deviation 0.55
Values 2.9 3.9 4.2 3.5
[197]
ref_hepatocyte PIK3R1
Mean 7.45
Standard deviation 3.9
Values 4.1 7.4 4.2 8.1 14
[198]
HepG2 PIK3R1
Mean 11.9
Standard deviation 3
Values 9.8 14
[199]
HepG2.C3A PIK3R1
Mean 11.5
Standard deviation 2.6
Values 9.6 13
[200]
HuH.7 PIK3R1
Mean 23.4
Standard deviation 8.6
Values 23 32 15
[201]
SNU475 PIK3R1
Mean 57.3
Standard deviation 32
Values 80 35
[202]
THLE PIK3R1
Mean 45.5
Standard deviation 1.5
Values 44 47
[203]
liver PIK3R1
Mean 84.8
Standard deviation 47
Values 64 1e+02 32 1.4e+02
[204]
ref_hepatocyte UHMK1
Mean 7.11
Standard deviation 3.8
Values 6.2 13 5.1 3.1 7.9
[205]
HepG2 UHMK1
Mean 36.1
Standard deviation 19
Values 23 49
[206]
HepG2.C3A UHMK1
Mean 34.8
Standard deviation 11
Values 27 43
[207]
HuH.7 UHMK1
Mean 45.9
Standard deviation 9
Values 52 50 36
[208]
SNU475 UHMK1
Mean 101
Standard deviation 11
Values 1.1e+02 93
[209]
THLE UHMK1
Mean 88.6
Standard deviation 4.2
Values 86 92
[210]
liver UHMK1
Mean 88.3
Standard deviation 28
Values 67 1.2e+02 62 1.1e+02
[211]
ref_hepatocyte ELK1
Mean 6.81
Standard deviation 3.9
Values 1.7 12 7.5 8.5 4.4
[212]
HepG2 ELK1
Mean 12.1
Standard deviation 1.5
Values 13 11
[213]
HepG2.C3A ELK1
Mean 2.45
Standard deviation 0.82
Values 3 1.9
[214]
HuH.7 ELK1
Mean 12.6
Standard deviation 1.8
Values 14 11 13
[215]
SNU475 ELK1
Mean 15.1
Standard deviation 0.2
Values 15 15
[216]
THLE ELK1
Mean 25.4
Standard deviation 3.5
Values 23 28
[217]
liver ELK1
Mean 8.61
Standard deviation 2.4
Values 10 6 11 7.1
[218]
ref_hepatocyte GNAI1
Mean 6.48
Standard deviation 1.5
Values 6.5 8.9 6.3 4.7 6
[219]
HepG2 GNAI1
Mean 4.56
Standard deviation 1
Values 5.3 3.9
[220]
HepG2.C3A GNAI1
Mean 2.12
Standard deviation 0.54
Values 1.7 2.5
[221]
HuH.7 GNAI1
Mean 8.95
Standard deviation 1.2
Values 9.3 7.6 10
[222]
SNU475 GNAI1
Mean 27.6
Standard deviation 3.4
Values 30 25
[223]
THLE GNAI1
Mean 20
Standard deviation 0.41
Values 20 20
[224]
liver GNAI1
Mean 16.4
Standard deviation 11
Values 32 8.4 17 9
[225]
ref_hepatocyte SRF
Mean 6.43
Standard deviation 4.1
Values 9.2 3.7 12 6.2 1.5
[226]
HepG2 SRF
Mean 39.1
Standard deviation 3.7
Values 42 36
[227]
HepG2.C3A SRF
Mean 25.8
Standard deviation 4.2
Values 29 23
[228]
HuH.7 SRF
Mean 14.9
Standard deviation 1.6
Values 16 13 16
[229]
SNU475 SRF
Mean 34.4
Standard deviation 3.7
Values 37 32
[230]
THLE SRF
Mean 20.4
Standard deviation 3.8
Values 18 23
[231]
liver SRF
Mean 5.31
Standard deviation 3.4
Values 3.8 5.8 1.8 9.8
[232]
ref_hepatocyte ZDHHC7
Mean 5.8
Standard deviation 3.5
Values 12 6.3 4.6 4 2.4
[233]
HepG2 ZDHHC7
Mean 46.4
Standard deviation 2.7
Values 44 48
[234]
HepG2.C3A ZDHHC7
Mean 36.6
Standard deviation 8.7
Values 43 30
[235]
HuH.7 ZDHHC7
Mean 26.4
Standard deviation 1.4
Values 26 25 28
[236]
SNU475 ZDHHC7
Mean 33.2
Standard deviation 9.1
Values 40 27
[237]
THLE ZDHHC7
Mean 28.5
Standard deviation 0.37
Values 29 28
[238]
liver ZDHHC7
Mean 6.75
Standard deviation 2.4
Values 3.7 9.5 6.8 7
[239]
ref_hepatocyte EGFR
Mean 5.53
Standard deviation 4.2
Values 0.94 8.5 11 3.5 3.5
[240]
HepG2 EGFR
Mean 7.53
Standard deviation 0.89
Values 6.9 8.2
[241]
HepG2.C3A EGFR
Mean 5.18
Standard deviation 0.67
Values 5.7 4.7
[242]
HuH.7 EGFR
Mean 36.6
Standard deviation 25
Values 32 63 15
[243]
SNU475 EGFR
Mean 13.7
Standard deviation 0.74
Values 13 14
[244]
THLE EGFR
Mean 23.6
Standard deviation 4.4
Values 20 27
[245]
liver EGFR
Mean 49.4
Standard deviation 14
Values 39 69 47 42
[246]
ref_hepatocyte PIK3R2
Mean 5.25
Standard deviation 3.4
Values 11 3.2 3.1 4.9 3.8
[247]
HepG2 PIK3R2
Mean 42.5
Standard deviation 2.8
Values 44 41
[248]
HepG2.C3A PIK3R2
Mean 44.2
Standard deviation 13
Values 53 35
[249]
HuH.7 PIK3R2
Mean 64.7
Standard deviation 10
Values 75 55 64
[250]
SNU475 PIK3R2
Mean 15.7
Standard deviation 3.3
Values 18 13
[251]
THLE PIK3R2
Mean 26
Standard deviation 2.8
Values 24 28
[252]
liver PIK3R2
Mean 6.1
Standard deviation 1.7
Values 7.6 6 3.8 6.9
[253]
ref_hepatocyte AREG
Mean 5.24
Standard deviation 9.3
Values 1.7 22 1.7 0.57 0.4
[254]
HepG2 AREG
Mean 1.59
Standard deviation 1.3
Values 2.5 0.67
[255]
HepG2.C3A AREG
Mean 0.15
Standard deviation 0.061
Values 0.11 0.19
[256]
HuH.7 AREG
Mean 0.0425
Standard deviation 0.021
Values 0.057 0.051 0.019
[257]
SNU475 AREG
Mean 0.0116
Standard deviation 0.016
Values 0.023 0
[258]
THLE AREG
Mean 16.4
Standard deviation 1.7
Values 15 18
[259]
liver AREG
Mean 0.00588
Standard deviation 0.012
Values 0.024 0 0 0
[260]
ref_hepatocyte GNB5
Mean 4.79
Standard deviation 2.5
Values 6.3 6.9 2 6.5 2.2
[261]
HepG2 GNB5
Mean 11.3
Standard deviation 2.9
Values 13 9.2
[262]
HepG2.C3A GNB5
Mean 10.4
Standard deviation 1.2
Values 11 9.5
[263]
HuH.7 GNB5
Mean 20.1
Standard deviation 2.5
Values 20 23 18
[264]
SNU475 GNB5
Mean 15.2
Standard deviation 0.29
Values 15 15
[265]
THLE GNB5
Mean 18.5
Standard deviation 0.68
Values 18 19
[266]
liver GNB5
Mean 12.6
Standard deviation 4.4
Values 13 12 18 7.3
[267]
ref_hepatocyte MAPK3
Mean 4.16
Standard deviation 1.3
Values 5.1 2.8 3.6 6 3.3
[268]
HepG2 MAPK3
Mean 33.1
Standard deviation 5.2
Values 37 29
[269]
HepG2.C3A MAPK3
Mean 30.4
Standard deviation 12
Values 39 22
[270]
HuH.7 MAPK3
Mean 30
Standard deviation 4.8
Values 34 25 32
[271]
SNU475 MAPK3
Mean 10.2
Standard deviation 2.4
Values 12 8.5
[272]
THLE MAPK3
Mean 11.6
Standard deviation 1.1
Values 11 12
[273]
liver MAPK3
Mean 2.87
Standard deviation 2.4
Values 5 0.81 4.8 0.82
[274]
ref_hepatocyte SRC
Mean 3.67
Standard deviation 3.6
Values 9.6 4.7 2.2 0.77 1.2
[275]
HepG2 SRC
Mean 66
Standard deviation 21
Values 81 51
[276]
HepG2.C3A SRC
Mean 58.1
Standard deviation 18
Values 71 45
[277]
HuH.7 SRC
Mean 27.9
Standard deviation 2
Values 28 29 26
[278]
SNU475 SRC
Mean 35.6
Standard deviation 3.5
Values 38 33
[279]
THLE SRC
Mean 22.5
Standard deviation 2.7
Values 21 24
[280]
liver SRC
Mean 2.9
Standard deviation 1
Values 4.1 2.5 1.7 3.2
[281]
ref_hepatocyte PDPK1
Mean 3.54
Standard deviation 2
Values 6.9 3.4 3.6 1.8 2
[282]
HepG2 PDPK1
Mean 39.4
Standard deviation 5.6
Values 35 43
[283]
HepG2.C3A PDPK1
Mean 80.1
Standard deviation 13
Values 89 71
[284]
HuH.7 PDPK1
Mean 31.4
Standard deviation 4.5
Values 35 33 26
[285]
SNU475 PDPK1
Mean 17.6
Standard deviation 0.21
Values 17 18
[286]
THLE PDPK1
Mean 25.9
Standard deviation 4.6
Values 23 29
[287]
liver PDPK1
Mean 28.5
Standard deviation 5.1
Values 34 27 22 31
[288]
ref_hepatocyte FOXO3
Mean 2.79
Standard deviation 0.38
Values 3.3 2.7 2.3 2.8 2.9
[289]
HepG2 FOXO3
Mean 8.44
Standard deviation 1
Values 7.7 9.2
[290]
HepG2.C3A FOXO3
Mean 8
Standard deviation 2.4
Values 9.7 6.3
[291]
HuH.7 FOXO3
Mean 11.9
Standard deviation 3.6
Values 13 15 7.9
[292]
SNU475 FOXO3
Mean 6.76
Standard deviation 0.76
Values 7.3 6.2
[293]
THLE FOXO3
Mean 17.9
Standard deviation 3.1
Values 16 20
[294]
liver FOXO3
Mean 20
Standard deviation 5.5
Values 24 21 12 23
[295]
ref_hepatocyte TGFA
Mean 2
Standard deviation 1.3
Values 3.8 2.7 2.1 0.72 0.76
[296]
HepG2 TGFA
Mean 15.3
Standard deviation 2.1
Values 17 14
[297]
HepG2.C3A TGFA
Mean 28.4
Standard deviation 4.2
Values 25 31
[298]
HuH.7 TGFA
Mean 0.0129
Standard deviation 0.0035
Values 0.016 0.013 0.0094
[299]
SNU475 TGFA
Mean 1.88
Standard deviation 0.53
Values 1.5 2.3
[300]
THLE TGFA
Mean 0.903
Standard deviation 0.47
Values 1.2 0.57
[301]
liver TGFA
Mean 2.16
Standard deviation 0.15
Values 2.1 2.3 2.2 2
[302]
ref_hepatocyte PIK3CA
Mean 1.87
Standard deviation 0.73
Values 2.3 2.6 2.3 1.2 0.94
[303]
HepG2 PIK3CA
Mean 3.17
Standard deviation 1.6
Values 2.1 4.3
[304]
HepG2.C3A PIK3CA
Mean 8.78
Standard deviation 1.1
Values 8 9.6
[305]
HuH.7 PIK3CA
Mean 9.59
Standard deviation 2.4
Values 10 12 7
[306]
SNU475 PIK3CA
Mean 7.49
Standard deviation 0.93
Values 8.1 6.8
[307]
THLE PIK3CA
Mean 9.67
Standard deviation 0.66
Values 10 9.2
[308]
liver PIK3CA
Mean 9.99
Standard deviation 4.7
Values 6.1 15 6 13
[309]
ref_hepatocyte HBEGF
Mean 1.81
Standard deviation 1.5
Values 1 3.1 3.8 0.78 0.34
[310]
HepG2 HBEGF
Mean 2.02
Standard deviation 0.16
Values 2.1 1.9
[311]
HepG2.C3A HBEGF
Mean 1.02
Standard deviation 0.3
Values 1.2 0.82
[312]
HuH.7 HBEGF
Mean 0.469
Standard deviation 0.044
Values 0.52 0.43 0.46
[313]
SNU475 HBEGF
Mean 4.11
Standard deviation 0.34
Values 3.9 4.4
[314]
THLE HBEGF
Mean 3.71
Standard deviation 0.17
Values 3.8 3.6
[315]
liver HBEGF
Mean 0.478
Standard deviation 0.29
Values 0.89 0.27 0.28 0.46
[316]
ref_hepatocyte CREB1
Mean 1.8
Standard deviation 1.2
Values 3.7 2.1 1.5 0.96 0.81
[317]
HepG2 CREB1
Mean 13.1
Standard deviation 2.8
Values 11 15
[318]
HepG2.C3A CREB1
Mean 26.1
Standard deviation 3.2
Values 24 28
[319]
HuH.7 CREB1
Mean 35.1
Standard deviation 4
Values 38 36 31
[320]
SNU475 CREB1
Mean 19.3
Standard deviation 0.081
Values 19 19
[321]
THLE CREB1
Mean 20.8
Standard deviation 2.1
Values 22 19
[322]
liver CREB1
Mean 13
Standard deviation 3.1
Values 12 16 9.3 15
[323]
ref_hepatocyte ESR1
Mean 1.54
Standard deviation 2.3
Values 0 0.17 0 2.2 5.3
[324]
HepG2 ESR1
Mean 0.0215
Standard deviation 0.018
Values 0.034 0.0086
[325]
HepG2.C3A ESR1
Mean 0
Standard deviation 0
Values 0 0
[326]
HuH.7 ESR1
Mean 0.0525
Standard deviation 0.047
Values 0.11 0.032 0.019
[327]
SNU475 ESR1
Mean 0.157
Standard deviation 0.14
Values 0.06 0.25
[328]
THLE ESR1
Mean 0.0367
Standard deviation 0.0067
Values 0.041 0.032
[329]
liver ESR1
Mean 11.5
Standard deviation 7
Values 7.2 11 6.1 22
[330]
ref_hepatocyte GNG11
Mean 1.51
Standard deviation 1.6
Values 0 0 1.3 3.2 3
[331]
HepG2 GNG11
Mean 0.0115
Standard deviation 0.016
Values 0.023 0
[332]
HepG2.C3A GNG11
Mean 0.0102
Standard deviation 0.00071
Values 0.0097 0.011
[333]
HuH.7 GNG11
Mean 0.0158
Standard deviation 0.022
Values 0.041 0.0064 0
[334]
SNU475 GNG11
Mean 13.3
Standard deviation 2
Values 12 15
[335]
THLE GNG11
Mean 37.1
Standard deviation 6.4
Values 33 42
[336]
liver GNG11
Mean 10.1
Standard deviation 8.8
Values 16 3.1 19 2
[337]
ref_hepatocyte STRN
Mean 1.09
Standard deviation 0.66
Values 1 1.8 1.7 0.36 0.54
[338]
HepG2 STRN
Mean 9.37
Standard deviation 2.4
Values 7.7 11
[339]
HepG2.C3A STRN
Mean 16.3
Standard deviation 1.3
Values 15 17
[340]
HuH.7 STRN
Mean 12
Standard deviation 3.1
Values 14 14 8.4
[341]
SNU475 STRN
Mean 20
Standard deviation 0.35
Values 20 20
[342]
THLE STRN
Mean 20.8
Standard deviation 0.87
Values 20 21
[343]
liver STRN
Mean 11.5
Standard deviation 5
Values 9.4 16 5.4 15
[344]
ref_hepatocyte GNG7
Mean 0.972
Standard deviation 0.89
Values 2.2 0.22 0.098 0.76 1.6
[345]
HepG2 GNG7
Mean 6.31
Standard deviation 1.2
Values 7.2 5.5
[346]
HepG2.C3A GNG7
Mean 4.41
Standard deviation 1.7
Values 5.6 3.2
[347]
HuH.7 GNG7
Mean 7.39
Standard deviation 1.1
Values 8.1 6.1 7.9
[348]
SNU475 GNG7
Mean 0.379
Standard deviation 0.19
Values 0.51 0.24
[349]
THLE GNG7
Mean 0.654
Standard deviation 0.35
Values 0.9 0.41
[350]
liver GNG7
Mean 1.4
Standard deviation 0.99
Values 2.8 0.53 1.3 1
[351]
ref_hepatocyte BTC
Mean 0.915
Standard deviation 1.9
Values 0 4.4 0.079 0 0.12
[352]
HepG2 BTC
Mean 0.00716
Standard deviation 0.002
Values 0.0057 0.0086
[353]
HepG2.C3A BTC
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[354]
HuH.7 BTC
Mean 0.087
Standard deviation 0.09
Values 0.066 0.19 0.0094
[355]
SNU475 BTC
Mean 0.229
Standard deviation 0.03
Values 0.25 0.21
[356]
THLE BTC
Mean 0.251
Standard deviation 0.13
Values 0.34 0.16
[357]
liver BTC
Mean 0.172
Standard deviation 0.058
Values 0.21 0.23 0.1 0.15
[358]
ref_hepatocyte MMP9
Mean 0.779
Standard deviation 1.6
Values 0.1 0.049 3.7 0.06 0.033
[359]
HepG2 MMP9
Mean 0.261
Standard deviation 0.18
Values 0.39 0.13
[360]
HepG2.C3A MMP9
Mean 0.112
Standard deviation 0.0078
Values 0.11 0.12
[361]
HuH.7 MMP9
Mean 0.0205
Standard deviation 0.012
Values 0.033 0.019 0.0094
[362]
SNU475 MMP9
Mean 0.53
Standard deviation 0.7
Values 0.037 1
[363]
THLE MMP9
Mean 0.101
Standard deviation 0.076
Values 0.047 0.15
[364]
liver MMP9
Mean 1
Standard deviation 0.93
Values 0.33 0.73 0.59 2.4
[365]
ref_hepatocyte IGF1R
Mean 0.745
Standard deviation 1.4
Values 3.3 0.021 0.29 0.043 0.065
[366]
HepG2 IGF1R
Mean 44
Standard deviation 16
Values 55 33
[367]
HepG2.C3A IGF1R
Mean 24.3
Standard deviation 6.5
Values 29 20
[368]
HuH.7 IGF1R
Mean 9.29
Standard deviation 2.1
Values 12 7.5 8.8
[369]
SNU475 IGF1R
Mean 30.3
Standard deviation 1.7
Values 32 29
[370]
THLE IGF1R
Mean 24.8
Standard deviation 4.5
Values 22 28
[371]
liver IGF1R
Mean 4.51
Standard deviation 2.6
Values 2.4 5.8 2.2 7.6
[372]
ref_hepatocyte GNG4
Mean 0.665
Standard deviation 1.2
Values 2.8 0.17 0.098 0.15 0.11
[373]
HepG2 GNG4
Mean 16.3
Standard deviation 4.5
Values 19 13
[374]
HepG2.C3A GNG4
Mean 3.08
Standard deviation 0.29
Values 2.9 3.3
[375]
HuH.7 GNG4
Mean 41.2
Standard deviation 8.1
Values 48 32 43
[376]
SNU475 GNG4
Mean 2.92
Standard deviation 0.47
Values 3.3 2.6
[377]
THLE GNG4
Mean 0.755
Standard deviation 0.19
Values 0.89 0.62
[378]
liver GNG4
Mean 0.161
Standard deviation 0.098
Values 0.024 0.26 0.18 0.19
[379]
ref_hepatocyte ZDHHC21
Mean 0.524
Standard deviation 0.13
Values 0.67 0.6 0.54 0.32 0.5
[380]
HepG2 ZDHHC21
Mean 4.21
Standard deviation 2.1
Values 2.7 5.7
[381]
HepG2.C3A ZDHHC21
Mean 6.79
Standard deviation 1.4
Values 5.8 7.8
[382]
HuH.7 ZDHHC21
Mean 0.176
Standard deviation 0.13
Values 0.12 0.32 0.084
[383]
SNU475 ZDHHC21
Mean 9.43
Standard deviation 1.3
Values 10 8.5
[384]
THLE ZDHHC21
Mean 7.2
Standard deviation 0.98
Values 7.9 6.5
[385]
liver ZDHHC21
Mean 12.1
Standard deviation 5.7
Values 7.8 20 8.6 12
[386]
ref_hepatocyte PIK3R3
Mean 0.405
Standard deviation 0.3
Values 0.52 0.81 0.47 0.078 0.15
[387]
HepG2 PIK3R3
Mean 2.95
Standard deviation 2.5
Values 1.2 4.7
[388]
HepG2.C3A PIK3R3
Mean 2.65
Standard deviation 1.6
Values 1.5 3.8
[389]
HuH.7 PIK3R3
Mean 4.56
Standard deviation 1.3
Values 5.7 3.1 5
[390]
SNU475 PIK3R3
Mean 6.68
Standard deviation 0.22
Values 6.5 6.8
[391]
THLE PIK3R3
Mean 3.8
Standard deviation 0.9
Values 3.2 4.4
[392]
liver PIK3R3
Mean 3.68
Standard deviation 0.27
Values 3.7 3.8 3.3 4
[393]
ref_hepatocyte GNB4
Mean 0.389
Standard deviation 0.25
Values 0.16 0.31 0.7 0.17 0.61
[394]
HepG2 GNB4
Mean 0.666
Standard deviation 0.063
Values 0.71 0.62
[395]
HepG2.C3A GNB4
Mean 0.835
Standard deviation 0.043
Values 0.87 0.8
[396]
HuH.7 GNB4
Mean 1.6
Standard deviation 0.14
Values 1.6 1.7 1.5
[397]
SNU475 GNB4
Mean 4.59
Standard deviation 0.038
Values 4.6 4.6
[398]
THLE GNB4
Mean 34.3
Standard deviation 7.5
Values 29 40
[399]
liver GNB4
Mean 9.42
Standard deviation 4.4
Values 4.9 15 7 11
[400]
ref_hepatocyte AKT3
Mean 0.387
Standard deviation 0.32
Values 0 0.53 0.83 0.16 0.41
[401]
HepG2 AKT3
Mean 0.238
Standard deviation 0.15
Values 0.34 0.13
[402]
HepG2.C3A AKT3
Mean 0.036
Standard deviation 0.0097
Values 0.029 0.043
[403]
HuH.7 AKT3
Mean 0.0557
Standard deviation 0.031
Values 0.049 0.09 0.028
[404]
SNU475 AKT3
Mean 40.8
Standard deviation 10
Values 48 34
[405]
THLE AKT3
Mean 22.1
Standard deviation 4.4
Values 25 19
[406]
liver AKT3
Mean 6.71
Standard deviation 4.9
Values 2.8 12 2.3 9.4
[407]
ref_hepatocyte S1PR3
Mean 0.365
Standard deviation 0.38
Values 0 0.17 0.78 0.77 0.11
[408]
HepG2 S1PR3
Mean 0.215
Standard deviation 0.02
Values 0.23 0.2
[409]
HepG2.C3A S1PR3
Mean 0.0915
Standard deviation 0.0081
Values 0.097 0.086
[410]
HuH.7 S1PR3
Mean 0.239
Standard deviation 0.08
Values 0.32 0.24 0.16
[411]
SNU475 S1PR3
Mean 15.1
Standard deviation 0.43
Values 15 15
[412]
THLE S1PR3
Mean 34.4
Standard deviation 3.4
Values 37 32
[413]
liver S1PR3
Mean 2.68
Standard deviation 0.32
Values 2.4 2.4 2.9 3
[414]
ref_hepatocyte GNG2
Mean 0.352
Standard deviation 0.41
Values 0 0.06 0.53 0.18 0.99
[415]
HepG2 GNG2
Mean 0.01
Standard deviation 0.002
Values 0.011 0.0086
[416]
HepG2.C3A GNG2
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[417]
HuH.7 GNG2
Mean 0
Standard deviation 0
Values 0 0 0
[418]
SNU475 GNG2
Mean 5.62
Standard deviation 1.4
Values 4.6 6.6
[419]
THLE GNG2
Mean 4.37
Standard deviation 0.87
Values 5 3.8
[420]
liver GNG2
Mean 3.44
Standard deviation 0.91
Values 3.5 3.6 4.4 2.2
[421]
ref_hepatocyte NOS3
Mean 0.251
Standard deviation 0.22
Values 0.58 0.37 0.014 0.12 0.18
[422]
HepG2 NOS3
Mean 15.1
Standard deviation 1.3
Values 14 16
[423]
HepG2.C3A NOS3
Mean 1.81
Standard deviation 0.061
Values 1.8 1.9
[424]
HuH.7 NOS3
Mean 1.2
Standard deviation 0.2
Values 1.4 1 1.2
[425]
SNU475 NOS3
Mean 0.48
Standard deviation 0.28
Values 0.68 0.28
[426]
THLE NOS3
Mean 1.36
Standard deviation 0.21
Values 1.5 1.2
[427]
liver NOS3
Mean 2.44
Standard deviation 1.3
Values 1.5 2.3 1.6 4.3
[428]
ref_hepatocyte EREG
Mean 0.24
Standard deviation 0.13
Values 0.3 0.18 0.15 0.13 0.45
[429]
HepG2 EREG
Mean 1.79
Standard deviation 1.2
Values 2.6 0.95
[430]
HepG2.C3A EREG
Mean 1.51
Standard deviation 1
Values 0.81 2.2
[431]
HuH.7 EREG
Mean 0.068
Standard deviation 0.032
Values 0.033 0.096 0.075
[432]
SNU475 EREG
Mean 0.149
Standard deviation 0.12
Values 0.065 0.23
[433]
THLE EREG
Mean 6.34
Standard deviation 2.2
Values 7.9 4.8
[434]
liver EREG
Mean 0.123
Standard deviation 0.11
Values 0 0.13 0.26 0.11
[435]
ref_hepatocyte MMP7
Mean 0.19
Standard deviation 0.26
Values 0 0 0.62 0.25 0.081
[436]
HepG2 MMP7
Mean 0.561
Standard deviation 0.09
Values 0.62 0.5
[437]
HepG2.C3A MMP7
Mean 0.0726
Standard deviation 0.034
Values 0.049 0.097
[438]
HuH.7 MMP7
Mean 0
Standard deviation 0
Values 0 0 0
[439]
SNU475 MMP7
Mean 2.03
Standard deviation 0.32
Values 1.8 2.3
[440]
THLE MMP7
Mean 0.0594
Standard deviation 0.016
Values 0.071 0.048
[441]
liver MMP7
Mean 0.441
Standard deviation 0.33
Values 0.92 0.16 0.31 0.38
[442]
ref_hepatocyte MMP2
Mean 0.154
Standard deviation 0.2
Values 0.035 0 0.11 0.13 0.5
[443]
HepG2 MMP2
Mean 3.68
Standard deviation 0.49
Values 4 3.3
[444]
HepG2.C3A MMP2
Mean 0.0258
Standard deviation 0.009
Values 0.019 0.032
[445]
HuH.7 MMP2
Mean 0.06
Standard deviation 0.02
Values 0.066 0.077 0.037
[446]
SNU475 MMP2
Mean 49
Standard deviation 13
Values 39 59
[447]
THLE MMP2
Mean 40.2
Standard deviation 12
Values 31 49
[448]
liver MMP2
Mean 3.34
Standard deviation 1.2
Values 4.6 1.8 3.4 3.7
[449]
ref_hepatocyte GNGT2
Mean 0.154
Standard deviation 0.23
Values 0 0 0.06 0.16 0.54
[450]
HepG2 GNGT2
Mean 0
Standard deviation 0
Values 0 0
[451]
HepG2.C3A GNGT2
Mean 0
Standard deviation 0
Values 0 0
[452]
HuH.7 GNGT2
Mean 0
Standard deviation 0
Values 0 0 0
[453]
SNU475 GNGT2
Mean 0.0673
Standard deviation 0.062
Values 0.023 0.11
[454]
THLE GNGT2
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[455]
liver GNGT2
Mean 0.235
Standard deviation 0.19
Values 0.35 0.086 0.44 0.066
[456]
ref_hepatocyte GNG3
Mean 0.127
Standard deviation 0.2
Values 0 0 0 0.46 0.18
[457]
HepG2 GNG3
Mean 0.155
Standard deviation 0.032
Values 0.18 0.13
[458]
HepG2.C3A GNG3
Mean 0.493
Standard deviation 0.33
Values 0.73 0.26
[459]
HuH.7 GNG3
Mean 0.101
Standard deviation 0.06
Values 0.033 0.15 0.12
[460]
SNU475 GNG3
Mean 0.144
Standard deviation 0.053
Values 0.18 0.11
[461]
THLE GNG3
Mean 0.13
Standard deviation 0.018
Values 0.14 0.12
[462]
liver GNG3
Mean 0.17
Standard deviation 0.089
Values 0.047 0.26 0.21 0.17
[463]
ref_hepatocyte BCL2
Mean 0.0984
Standard deviation 0.087
Values 0.019 0 0.15 0.12 0.2
[464]
HepG2 BCL2
Mean 0.0301
Standard deviation 0.0061
Values 0.034 0.026
[465]
HepG2.C3A BCL2
Mean 1.13
Standard deviation 0.21
Values 1.3 0.99
[466]
HuH.7 BCL2
Mean 0.00642
Standard deviation 0.011
Values 0 0.019 0
[467]
SNU475 BCL2
Mean 0.618
Standard deviation 0.094
Values 0.55 0.68
[468]
THLE BCL2
Mean 0.568
Standard deviation 0.0088
Values 0.56 0.57
[469]
liver BCL2
Mean 1.31
Standard deviation 1
Values 0.49 1.8 0.49 2.5
[470]
ref_hepatocyte GNB3
Mean 0.0571
Standard deviation 0.11
Values 0.24 0 0 0 0.041
[471]
HepG2 GNB3
Mean 0.379
Standard deviation 0.11
Values 0.3 0.45
[472]
HepG2.C3A GNB3
Mean 1.61
Standard deviation 0.27
Values 1.4 1.8
[473]
HuH.7 GNB3
Mean 0.95
Standard deviation 0.47
Values 0.98 0.47 1.4
[474]
SNU475 GNB3
Mean 0.211
Standard deviation 0.003
Values 0.21 0.21
[475]
THLE GNB3
Mean 1.55
Standard deviation 0.56
Values 1.9 1.1
[476]
liver GNB3
Mean 0.0253
Standard deviation 0.019
Values 0.047 0.029 0.026 0
[477]
ref_hepatocyte ESR2
Mean 0.0345
Standard deviation 0.077
Values 0 0 0 0.17 0
[478]
HepG2 ESR2
Mean 0.0515
Standard deviation 0.024
Values 0.034 0.069
[479]
HepG2.C3A ESR2
Mean 0.0593
Standard deviation 0.054
Values 0.097 0.021
[480]
HuH.7 ESR2
Mean 0.0579
Standard deviation 0.035
Values 0.049 0.096 0.028
[481]
SNU475 ESR2
Mean 0.0984
Standard deviation 0.047
Values 0.065 0.13
[482]
THLE ESR2
Mean 0.118
Standard deviation 0.00092
Values 0.12 0.12
[483]
liver ESR2
Mean 0.283
Standard deviation 0.18
Values 0.24 0.2 0.15 0.54
[484]
ref_hepatocyte EGF
Mean 0.00415
Standard deviation 0.0093
Values 0 0.021 0 0 0
[485]
HepG2 EGF
Mean 0.0358
Standard deviation 0.014
Values 0.046 0.026
[486]
HepG2.C3A EGF
Mean 0.11
Standard deviation 0.087
Values 0.049 0.17
[487]
HuH.7 EGF
Mean 1.29
Standard deviation 0.44
Values 0.97 1.8 1.1
[488]
SNU475 EGF
Mean 3.97
Standard deviation 0.5
Values 4.3 3.6
[489]
THLE EGF
Mean 0.743
Standard deviation 0.02
Values 0.76 0.73
[490]
liver EGF
Mean 0.0176
Standard deviation 0.027
Values 0 0.057 0 0.013
[491]
ref_hepatocyte GNG13
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[492]
HepG2 GNG13
Mean 0
Standard deviation 0
Values 0 0
[493]
HepG2.C3A GNG13
Mean 0
Standard deviation 0
Values 0 0
[494]
HuH.7 GNG13
Mean 0.0152
Standard deviation 0.017
Values 0.033 0.013 0
[495]
SNU475 GNG13
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[496]
THLE GNG13
Mean 0.0142
Standard deviation 0.005
Values 0.018 0.011
[497]
liver GNG13
Mean 0
Standard deviation 0
Values 0 0 0 0
[498]
ref_hepatocyte EPGN
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[499]
HepG2 EPGN
Mean 0.0544
Standard deviation 0.028
Values 0.074 0.034
[500]
HepG2.C3A EPGN
Mean 0.0501
Standard deviation 0.025
Values 0.068 0.032
[501]
HuH.7 EPGN
Mean 0.127
Standard deviation 0.084
Values 0.082 0.22 0.075
[502]
SNU475 EPGN
Mean 0.503
Standard deviation 0.27
Values 0.31 0.69
[503]
THLE EPGN
Mean 4.76
Standard deviation 1.2
Values 5.6 3.9
[504]
liver EPGN
Mean 0.161
Standard deviation 0.11
Values 0.12 0.17 0.051 0.3
[505]
ref_hepatocyte GNGT1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[506]
HepG2 GNGT1
Mean 0
Standard deviation 0
Values 0 0
[507]
HepG2.C3A GNGT1
Mean 0
Standard deviation 0
Values 0 0
[508]
HuH.7 GNGT1
Mean 0.0409
Standard deviation 0.035
Values 0.0082 0.077 0.037
[509]
SNU475 GNGT1
Mean 0.0679
Standard deviation 0.0043
Values 0.065 0.071
[510]
THLE GNGT1
Mean 0
Standard deviation 0
Values 0 0
[511]
liver GNGT1
Mean 0
Standard deviation 0
Values 0 0 0 0
[512]
ref_hepatocyte GNG8
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[513]
HepG2 GNG8
Mean 0
Standard deviation 0
Values 0 0
[514]
HepG2.C3A GNG8
Mean 0
Standard deviation 0
Values 0 0
[515]
HuH.7 GNG8
Mean 0
Standard deviation 0
Values 0 0 0
[516]
SNU475 GNG8
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[517]
THLE GNG8
Mean 0
Standard deviation 0
Values 0 0
[518]
liver GNG8
Mean 0
Standard deviation 0
Values 0 0 0 0
[519]
ref_hepatocyte GNAT3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[520]
HepG2 GNAT3
Mean 0
Standard deviation 0
Values 0 0
[521]
HepG2.C3A GNAT3
Mean 0
Standard deviation 0
Values 0 0
[522]
HuH.7 GNAT3
Mean 0
Standard deviation 0
Values 0 0 0
[523]
SNU475 GNAT3
Mean 0.0287
Standard deviation 0.012
Values 0.037 0.02
[524]
THLE GNAT3
Mean 0
Standard deviation 0
Values 0 0
[525]
liver GNAT3
Mean 0
Standard deviation 0
Values 0 0 0 0