REACTOME_EXTENSION_OF_TELOMERES Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 NOP10 H/ACA ribonucleoprotein complex subunit 3 [1] -1.74[2] -1.96[3] -3.18[4] -2.72[5] -2.49[6] -1.30[7]
2 NHP2 H/ACA ribonucleoprotein complex subunit 2 [8] -1.52[9] -1.80[10] -1.57[11] -2.37[12] -1.87[13] -1.32[14]
3 PCNA Proliferating cell nuclear antigen [15] 0.97[16] 0.77[17] -0.94[18] -0.34[19] -0.08[20] -2.28[21]
4 POLD2 DNA polymerase delta subunit 2 [22] -0.52[23] -0.53[24] -0.32[25] -0.99[26] -0.64[27] 0.67[28]
5 POLD4 DNA polymerase delta subunit 4 [29] -2.05[30] -2.58[31] -0.80[32] 1.32[33] -2.29[34] 0.31[35]
6 RUVBL2 RuvB-like 2 [36] -0.08[37] -0.53[38] -0.11[39] -0.92[40] -0.34[41] -0.33[42]
7 RPA2 Replication protein A 32 kDa subunit [43] -1.38[44] -1.48[45] -1.22[46] -0.87[47] -0.81[48] -1.61[49]
8 TERF2IP Telomeric repeat-binding factor 2-interacting protein 1 [50] -0.53[51] -0.37[52] -0.68[53] -1.03[54] -0.65[55] -0.09[56]
9 DKC1 H/ACA ribonucleoprotein complex subunit 4 [57] 0.77[58] 0.57[59] -0.04[60] -0.28[61] -0.23[62] -0.31[63]
10 CHTF8 Chromosome transmission fidelity protein 8 homolog isoform 2 [64] 0.46[65] 0.12[66] 0.17[67] 0.13[68] 0.11[69] 0.15[70]
11 RUVBL1 RuvB-like 1 [71] 0.50[72] -0.06[73] -0.25[74] -0.77[75] -0.10[76] -0.68[77]
12 CDK2 Cyclin-dependent kinase 2 [78] -0.33[79] -0.35[80] -0.27[81] -0.14[82] 0.42[83] -1.40[84]
13 GAR1 H/ACA ribonucleoprotein complex subunit 1 [85] -1.07[86] -1.70[87] -2.29[88] -1.89[89] -1.58[90] -2.75[91]
14 RFC4 Replication factor C subunit 4 [92] -0.89[93] -0.44[94] -0.16[95] -1.09[96] 0.22[97] -1.96[98]
15 TEN1 CST complex subunit TEN1 [99] [100] [101] [102] [103] [104] [105]
16 PPP6R3 Serine/threonine-protein phosphatase 6 regulatory subunit 3 [106] 0.81[107] 1.09[108] 2.12[109] 2.72[110] 0.99[111] 2.28[112]
17 RFC1 Replication factor C subunit 1 [113] 0.22[114] 1.33[115] 1.41[116] 0.20[117] 1.02[118] 1.57[119]
18 RFC2 Replication factor C subunit 2 [120] -0.18[121] -0.51[122] -0.76[123] 0.06[124] 0.49[125] 0.02[126]
19 FEN1 Flap endonuclease 1 [127] 1.11[128] 0.72[129] 1.28[130] 0.55[131] 1.43[132] -0.31[133]
20 RPA1 Replication protein A 70 kDa DNA-binding subunit [134] 1.39[135] 0.95[136] 0.92[137] 1.73[138] 1.72[139] 0.79[140]
21 RPA3 Replication protein A 14 kDa subunit [141] -0.29[142] 0.34[143] 0.75[144] -1.03[145] -0.77[146] 0.10[147]
22 TINF2 TERF1-interacting nuclear factor 2 [148] 0.85[149] -0.67[150] -0.98[151] -0.22[152] -0.25[153] 0.59[154]
23 PPP6C Serine/threonine-protein phosphatase 6 catalytic subunit [155] 1.04[156] 0.88[157] 1.02[158] 1.21[159] 1.32[160] 1.55[161]
24 RFC5 Replication factor C subunit 5 [162] 0.21[163] 0.49[164] 0.39[165] 0.14[166] 0.65[167] -0.09[168]
25 TERF1 Telomeric repeat-binding factor 1 [169] -0.82[170] 0.15[171] 0.09[172] 1.11[173] 0.16[174] 0.76[175]
26 ANKRD28 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A 0.22[176] 1.15[177] 1.33[178] 0.16[179] 1.23[180] 2.71[181]
27 TERF2 Telomeric repeat-binding factor 2 [182] 0.38[183] 0.22[184] 0.68[185] -0.21[186] 0.17[187] 0.35[188]
28 SHQ1 Protein SHQ1 homolog [189] 0.05[190] -0.22[191] -1.04[192] -0.66[193] 0.44[194] 1.05[195]
29 CCNA2 Cyclin-A2 [196] 2.29[197] 3.12[198] 2.16[199] 1.88[200] 3.25[201] -0.44[202]
30 RFC3 Replication factor C subunit 3 [203] 1.25[204] 1.94[205] 1.78[206] 1.13[207] 1.70[208] -0.08[209]
31 LIG1 DNA ligase 1 [210] 1.71[211] 1.55[212] 1.89[213] 0.39[214] 1.10[215] 0.42[216]
32 POLA2 DNA polymerase alpha subunit B [217] 0.72[218] 0.18[219] 0.44[220] 1.39[221] 1.67[222] -0.05[223]
33 PRIM1 DNA primase small subunit [224] 0.75[225] 1.90[226] 1.93[227] 1.04[228] 1.60[229] -0.12[230]
34 POLD1 DNA polymerase delta catalytic subunit [231] 1.94[232] 1.98[233] 2.50[234] 1.70[235] 2.44[236] 1.46[237]
35 PRIM2 DNA primase large subunit [238] 1.36[239] 0.98[240] 0.30[241] 1.06[242] 1.28[243] -0.80[244]
36 POT1 Protection of telomeres protein 1 [245] 0.09[246] 1.20[247] 1.14[248] 1.64[249] 1.37[250] 1.58[251]
37 WRAP53 Telomerase Cajal body protein 1 [252] 1.03[253] 0.45[254] 1.02[255] 0.11[256] 0.96[257] -0.64[258]
38 ACD Adrenocortical dysplasia protein homolog [259] 1.78[260] 1.87[261] 1.34[262] 0.63[263] 1.34[264] 0.10[265]
39 DSCC1 Sister chromatid cohesion protein DCC1 [266] 0.83[267] 1.36[268] 1.93[269] 1.59[270] 1.06[271] -1.06[272]
40 POLD3 DNA polymerase delta subunit 3 [273] 1.25[274] 0.95[275] 1.62[276] 1.99[277] 2.45[278] 1.77[279]
41 RTEL1 Regulator of telomere elongation helicase 1 [280] -1.62[281] -0.67[282] -2.79[283] -2.41[284] -1.86[285] -0.86[286]
42 WRN Werner syndrome ATP-dependent helicase [287] 0.69[288] 1.97[289] 3.61[290] 1.58[291] 1.37[292] 2.76[293]
43 CTC1 CST complex subunit CTC1 [294] 2.04[295] 2.06[296] 2.73[297] 1.60[298] 1.60[299] 2.87[300]
44 POLA1 DNA polymerase alpha catalytic subunit [301] 2.09[302] 2.02[303] 2.28[304] 2.86[305] 2.81[306] 2.46[307]
45 CHTF18 Chromosome transmission fidelity protein 18 homolog [308] 1.49[309] 2.14[310] 2.44[311] 1.23[312] 2.02[313] 0.52[314]
46 DNA2 DNA replication ATP-dependent helicase/nuclease DNA2 [315] 1.84[316] 3.43[317] 2.33[318] 2.52[319] 2.16[320] 2.35[321]
47 BLM Bloom syndrome protein [322] 1.62[323] 2.80[324] 3.30[325] 2.77[326] 2.83[327] 0.41[328]
48 PIF1 ATP-dependent DNA helicase PIF1 [329] 2.09[330] 3.81[331] 3.56[332] 2.51[333] 3.20[334] 0.60[335]
49 TERT Telomerase reverse transcriptase [336] 3.57[337] 3.15[338] 3.78[339] 2.06[340] -4.01[341] -3.11[342]
50 CCNA1 Cyclin-A1 [343] [344] -3.49[345] [346] -0.91[347] 6.47[348] [349]
51 STN1 CST complex subunit STN1 [350] [351] [352] [353] [354] [355] [356]
[1]
ref_hepatocyte NOP10
Mean 76
Standard deviation 53
Values 13 28 1.3e+02 1.3e+02 87
[2]
HepG2 NOP10
Mean 47.6
Standard deviation 0.51
Values 48 47
[3]
HepG2.C3A NOP10
Mean 41.1
Standard deviation 11
Values 33 49
[4]
HuH.7 NOP10
Mean 20.9
Standard deviation 8.3
Values 19 14 30
[5]
SNU475 NOP10
Mean 23.1
Standard deviation 2.4
Values 25 21
[6]
THLE NOP10
Mean 30.8
Standard deviation 0.77
Values 30 31
[7]
liver NOP10
Mean 25.5
Standard deviation 22
Values 49 8.5 38 5.8
[8]
ref_hepatocyte NHP2
Mean 49.9
Standard deviation 22
Values 28 77 37 70 38
[9]
HepG2 NHP2
Mean 36.4
Standard deviation 5.5
Values 40 32
[10]
HepG2.C3A NHP2
Mean 30.1
Standard deviation 7.3
Values 25 35
[11]
HuH.7 NHP2
Mean 42
Standard deviation 19
Values 47 21 58
[12]
SNU475 NHP2
Mean 19.3
Standard deviation 1.3
Values 20 18
[13]
THLE NHP2
Mean 31
Standard deviation 4.5
Values 28 34
[14]
liver NHP2
Mean 16.4
Standard deviation 14
Values 24 4.8 32 4.1
[15]
ref_hepatocyte PCNA
Mean 36
Standard deviation 33
Values 92 37 14 19 17
[16]
HepG2 PCNA
Mean 147
Standard deviation 54
Values 1.1e+02 1.9e+02
[17]
HepG2.C3A PCNA
Mean 130
Standard deviation 86
Values 69 1.9e+02
[18]
HuH.7 PCNA
Mean 46.8
Standard deviation 33
Values 53 10 76
[19]
SNU475 PCNA
Mean 56.8
Standard deviation 7.7
Values 51 62
[20]
THLE PCNA
Mean 77.4
Standard deviation 13
Values 68 86
[21]
liver PCNA
Mean 6.07
Standard deviation 2.5
Values 7.3 5.2 8.8 3
[22]
ref_hepatocyte POLD2
Mean 32.3
Standard deviation 18
Values 10 23 30 58 40
[23]
HepG2 POLD2
Mean 47
Standard deviation 5.6
Values 51 43
[24]
HepG2.C3A POLD2
Mean 47.2
Standard deviation 5.4
Values 43 51
[25]
HuH.7 POLD2
Mean 64.5
Standard deviation 25
Values 79 36 79
[26]
SNU475 POLD2
Mean 32.5
Standard deviation 4.3
Values 29 35
[27]
THLE POLD2
Mean 47.1
Standard deviation 7.9
Values 41 53
[28]
liver POLD2
Mean 42.1
Standard deviation 24
Values 67 21 57 23
[29]
ref_hepatocyte POLD4
Mean 31.5
Standard deviation 27
Values 1.6 16 19 64 57
[30]
HepG2 POLD4
Mean 15.9
Standard deviation 3.9
Values 19 13
[31]
HepG2.C3A POLD4
Mean 11.1
Standard deviation 4
Values 14 8.3
[32]
HuH.7 POLD4
Mean 45.1
Standard deviation 6.1
Values 39 51 46
[33]
SNU475 POLD4
Mean 157
Standard deviation 53
Values 1.9e+02 1.2e+02
[34]
THLE POLD4
Mean 14.6
Standard deviation 1.8
Values 13 16
[35]
liver POLD4
Mean 32.1
Standard deviation 32
Values 48 6 69 5.3
[36]
ref_hepatocyte RUVBL2
Mean 28.8
Standard deviation 12
Values 12 37 43 30 23
[37]
HepG2 RUVBL2
Mean 56.9
Standard deviation 17
Values 69 45
[38]
HepG2.C3A RUVBL2
Mean 41.9
Standard deviation 2
Values 41 43
[39]
HuH.7 RUVBL2
Mean 66.4
Standard deviation 27
Values 80 35 84
[40]
SNU475 RUVBL2
Mean 30.4
Standard deviation 3.9
Values 28 33
[41]
THLE RUVBL2
Mean 52
Standard deviation 2.8
Values 50 54
[42]
liver RUVBL2
Mean 18.9
Standard deviation 8.4
Values 20 15 30 10
[43]
ref_hepatocyte RPA2
Mean 23.6
Standard deviation 12
Values 23 41 28 15 11
[44]
HepG2 RPA2
Mean 19
Standard deviation 3.9
Values 16 22
[45]
HepG2.C3A RPA2
Mean 17.8
Standard deviation 8.2
Values 12 24
[46]
HuH.7 RPA2
Mean 25.2
Standard deviation 11
Values 27 14 35
[47]
SNU475 RPA2
Mean 25.9
Standard deviation 7.9
Values 20 31
[48]
THLE RPA2
Mean 30.6
Standard deviation 2.7
Values 29 33
[49]
liver RPA2
Mean 6.36
Standard deviation 3.6
Values 6.9 4.2 11 3.2
[50]
ref_hepatocyte TERF2IP
Mean 20.1
Standard deviation 5.4
Values 22 25 25 16 13
[51]
HepG2 TERF2IP
Mean 29
Standard deviation 0.8
Values 30 28
[52]
HepG2.C3A TERF2IP
Mean 32.6
Standard deviation 7.5
Values 38 27
[53]
HuH.7 TERF2IP
Mean 31.3
Standard deviation 5
Values 27 30 37
[54]
SNU475 TERF2IP
Mean 19.6
Standard deviation 0.25
Values 19 20
[55]
THLE TERF2IP
Mean 29.2
Standard deviation 1
Values 28 30
[56]
liver TERF2IP
Mean 15.5
Standard deviation 7.4
Values 23 9.1 21 9.1
[57]
ref_hepatocyte DKC1
Mean 17.8
Standard deviation 9.7
Values 24 30 18 10 6.4
[58]
HepG2 DKC1
Mean 63.7
Standard deviation 6.2
Values 68 59
[59]
HepG2.C3A DKC1
Mean 55.7
Standard deviation 4.5
Values 53 59
[60]
HuH.7 DKC1
Mean 43.3
Standard deviation 19
Values 49 23 58
[61]
SNU475 DKC1
Mean 29.3
Standard deviation 7.8
Values 24 35
[62]
THLE DKC1
Mean 34.8
Standard deviation 4.3
Values 32 38
[63]
liver DKC1
Mean 11.8
Standard deviation 4.9
Values 14 8.4 17 7
[64]
ref_hepatocyte CHTF8
Mean 15.3
Standard deviation 4.6
Values 9.3 12 17 21 17
[65]
HepG2 CHTF8
Mean 44
Standard deviation 2.7
Values 46 42
[66]
HepG2.C3A CHTF8
Mean 35.2
Standard deviation 6.4
Values 31 40
[67]
HuH.7 CHTF8
Mean 43
Standard deviation 8.3
Values 49 33 47
[68]
SNU475 CHTF8
Mean 33.6
Standard deviation 2.5
Values 32 35
[69]
THLE CHTF8
Mean 37.6
Standard deviation 8.5
Values 32 44
[70]
liver CHTF8
Mean 13.9
Standard deviation 2.6
Values 10 15 14 16
[71]
ref_hepatocyte RUVBL1
Mean 14.6
Standard deviation 5.5
Values 14 22 18 10 8.5
[72]
HepG2 RUVBL1
Mean 43.2
Standard deviation 11
Values 51 35
[73]
HepG2.C3A RUVBL1
Mean 29.5
Standard deviation 4.5
Values 26 33
[74]
HuH.7 RUVBL1
Mean 30.5
Standard deviation 13
Values 36 15 40
[75]
SNU475 RUVBL1
Mean 17.1
Standard deviation 3.3
Values 15 19
[76]
THLE RUVBL1
Mean 30.9
Standard deviation 6.8
Values 26 36
[77]
liver RUVBL1
Mean 7.48
Standard deviation 2.4
Values 9.4 6.5 9.5 4.5
[78]
ref_hepatocyte CDK2
Mean 12.1
Standard deviation 11
Values 19 28 3.3 5.7 4.6
[79]
HepG2 CDK2
Mean 20
Standard deviation 3.4
Values 18 22
[80]
HepG2.C3A CDK2
Mean 20
Standard deviation 9.1
Values 14 26
[81]
HuH.7 CDK2
Mean 24.9
Standard deviation 12
Values 30 11 33
[82]
SNU475 CDK2
Mean 21.8
Standard deviation 2.6
Values 20 24
[83]
THLE CDK2
Mean 36.9
Standard deviation 5.3
Values 33 41
[84]
liver CDK2
Mean 3.76
Standard deviation 1.3
Values 4.4 2.3 5.2 3.2
[85]
ref_hepatocyte GAR1
Mean 11
Standard deviation 6.7
Values 4.9 17 20 8.3 5.7
[86]
HepG2 GAR1
Mean 11
Standard deviation 2.3
Values 13 9.4
[87]
HepG2.C3A GAR1
Mean 7.16
Standard deviation 0.84
Values 6.6 7.8
[88]
HuH.7 GAR1
Mean 5.61
Standard deviation 2.2
Values 6.3 3.2 7.4
[89]
SNU475 GAR1
Mean 5.96
Standard deviation 0.37
Values 5.7 6.2
[90]
THLE GAR1
Mean 8.45
Standard deviation 0.75
Values 7.9 9
[91]
liver GAR1
Mean 1.35
Standard deviation 0.93
Values 2.1 0.78 2.2 0.34
[92]
ref_hepatocyte RFC4
Mean 11
Standard deviation 7.9
Values 17 21 9.8 4.7 2.4
[93]
HepG2 RFC4
Mean 12.4
Standard deviation 2.7
Values 10 14
[94]
HepG2.C3A RFC4
Mean 17
Standard deviation 7.7
Values 12 22
[95]
HuH.7 RFC4
Mean 24.4
Standard deviation 12
Values 26 12 35
[96]
SNU475 RFC4
Mean 10.3
Standard deviation 3.5
Values 7.8 13
[97]
THLE RFC4
Mean 29.1
Standard deviation 0.079
Values 29 29
[98]
liver RFC4
Mean 2.31
Standard deviation 1.2
Values 2.3 1.9 4 1
[99]
ref_hepatocyte TEN1
Mean 10
Standard deviation 5.9
Values 3 4.6 13 17 13
[100]
HepG2 TEN1
Missing
[101]
HepG2.C3A TEN1
Missing
[102]
HuH.7 TEN1
Missing
[103]
SNU475 TEN1
Missing
[104]
THLE TEN1
Missing
[105]
liver TEN1
Missing
[106]
ref_hepatocyte PPP6R3
Mean 9.96
Standard deviation 5.4
Values 16 15 7.6 4.3 6.5
[107]
HepG2 PPP6R3
Mean 36.6
Standard deviation 8.2
Values 31 42
[108]
HepG2.C3A PPP6R3
Mean 44.7
Standard deviation 6.4
Values 40 49
[109]
HuH.7 PPP6R3
Mean 108
Standard deviation 10
Values 1.2e+02 1e+02 1e+02
[110]
SNU475 PPP6R3
Mean 131
Standard deviation 1.3
Values 1.3e+02 1.3e+02
[111]
THLE PPP6R3
Mean 45.1
Standard deviation 0.76
Values 45 46
[112]
liver PPP6R3
Mean 39.8
Standard deviation 14
Values 31 48 25 55
[113]
ref_hepatocyte RFC1
Mean 9.26
Standard deviation 5.4
Values 15 15 7.1 4.1 5
[114]
HepG2 RFC1
Mean 22.5
Standard deviation 11
Values 15 30
[115]
HepG2.C3A RFC1
Mean 49.1
Standard deviation 4.6
Values 46 52
[116]
HuH.7 RFC1
Mean 61.4
Standard deviation 8.8
Values 66 67 51
[117]
SNU475 RFC1
Mean 21.2
Standard deviation 2
Values 20 23
[118]
THLE RFC1
Mean 42.7
Standard deviation 3.9
Values 45 40
[119]
liver RFC1
Mean 22.6
Standard deviation 3.4
Values 24 26 18 23
[120]
ref_hepatocyte RFC2
Mean 8.95
Standard deviation 3.2
Values 7.3 13 6.2 11 6.5
[121]
HepG2 RFC2
Mean 16.5
Standard deviation 2.8
Values 14 18
[122]
HepG2.C3A RFC2
Mean 13.3
Standard deviation 5.7
Values 9.3 17
[123]
HuH.7 RFC2
Mean 13.1
Standard deviation 6.2
Values 15 6.1 18
[124]
SNU475 RFC2
Mean 18.6
Standard deviation 4.4
Values 16 22
[125]
THLE RFC2
Mean 28.7
Standard deviation 3.4
Values 26 31
[126]
liver RFC2
Mean 7.44
Standard deviation 4.1
Values 10 4.9 11 3.1
[127]
ref_hepatocyte FEN1
Mean 8.88
Standard deviation 4.9
Values 17 9.6 7.8 7 3.4
[128]
HepG2 FEN1
Mean 40
Standard deviation 13
Values 31 49
[129]
HepG2.C3A FEN1
Mean 30.8
Standard deviation 20
Values 17 45
[130]
HuH.7 FEN1
Mean 53.6
Standard deviation 31
Values 63 19 79
[131]
SNU475 FEN1
Mean 26.1
Standard deviation 5.2
Values 22 30
[132]
THLE FEN1
Mean 54.6
Standard deviation 11
Values 47 62
[133]
liver FEN1
Mean 5.91
Standard deviation 2.9
Values 3.7 5.8 10 4.1
[134]
ref_hepatocyte RPA1
Mean 8.25
Standard deviation 3.9
Values 9.2 15 5.5 5.3 6.7
[135]
HepG2 RPA1
Mean 45.3
Standard deviation 8.3
Values 39 51
[136]
HepG2.C3A RPA1
Mean 33.6
Standard deviation 11
Values 26 41
[137]
HuH.7 RPA1
Mean 39
Standard deviation 14
Values 47 23 48
[138]
SNU475 RPA1
Mean 54.6
Standard deviation 1
Values 55 54
[139]
THLE RPA1
Mean 62.1
Standard deviation 11
Values 54 70
[140]
liver RPA1
Mean 11.7
Standard deviation 1.8
Values 12 12 14 9.5
[141]
ref_hepatocyte RPA3
Mean 8.22
Standard deviation 4.8
Values 6.2 7.6 1.9 11 15
[142]
HepG2 RPA3
Mean 14.1
Standard deviation 4
Values 11 17
[143]
HepG2.C3A RPA3
Mean 21.8
Standard deviation 13
Values 13 31
[144]
HuH.7 RPA3
Mean 34.5
Standard deviation 16
Values 35 18 50
[145]
SNU475 RPA3
Mean 8.05
Standard deviation 1.5
Values 9.1 7
[146]
THLE RPA3
Mean 11
Standard deviation 2.9
Values 8.9 13
[147]
liver RPA3
Mean 7.22
Standard deviation 6.1
Values 13 2.4 12 1.4
[148]
ref_hepatocyte TINF2
Mean 8.21
Standard deviation 1.3
Values 10 7.4 8.3 7.2 7.7
[149]
HepG2 TINF2
Mean 30.8
Standard deviation 1.5
Values 30 32
[150]
HepG2.C3A TINF2
Mean 10.8
Standard deviation 0.3
Values 11 11
[151]
HuH.7 TINF2
Mean 10.4
Standard deviation 1.3
Values 10 9 12
[152]
SNU475 TINF2
Mean 14.1
Standard deviation 0.013
Values 14 14
[153]
THLE TINF2
Mean 15.8
Standard deviation 1.4
Values 15 17
[154]
liver TINF2
Mean 10.2
Standard deviation 2.5
Values 12 7.3 12 8.9
[155]
ref_hepatocyte PPP6C
Mean 6.47
Standard deviation 1.2
Values 8 6.3 4.6 6.6 6.7
[156]
HepG2 PPP6C
Mean 27.9
Standard deviation 5.2
Values 24 32
[157]
HepG2.C3A PPP6C
Mean 25.1
Standard deviation 2.5
Values 23 27
[158]
HuH.7 PPP6C
Mean 32.8
Standard deviation 2.8
Values 33 35 30
[159]
SNU475 PPP6C
Mean 29.9
Standard deviation 1.7
Values 31 29
[160]
THLE PPP6C
Mean 37
Standard deviation 4.1
Values 34 40
[161]
liver PPP6C
Mean 15.5
Standard deviation 7.9
Values 24 9.2 20 8.4
[162]
ref_hepatocyte RFC5
Mean 5.54
Standard deviation 4.9
Values 13 7.4 0.42 3.6 3.2
[163]
HepG2 RFC5
Mean 13.4
Standard deviation 5.4
Values 9.6 17
[164]
HepG2.C3A RFC5
Mean 16.4
Standard deviation 10
Values 9 24
[165]
HuH.7 RFC5
Mean 18.1
Standard deviation 6.8
Values 23 10 21
[166]
SNU475 RFC5
Mean 12.2
Standard deviation 2.4
Values 11 14
[167]
THLE RFC5
Mean 19.8
Standard deviation 2.4
Values 18 22
[168]
liver RFC5
Mean 4.29
Standard deviation 1.7
Values 4.9 3.5 6.3 2.5
[169]
ref_hepatocyte TERF1
Mean 4.67
Standard deviation 2
Values 2.2 3.5 6.2 4.5 6.9
[170]
HepG2 TERF1
Mean 5.51
Standard deviation 1.4
Values 4.5 6.5
[171]
HepG2.C3A TERF1
Mean 10.9
Standard deviation 3
Values 8.8 13
[172]
HuH.7 TERF1
Mean 12.4
Standard deviation 1.1
Values 13 11 12
[173]
SNU475 TERF1
Mean 20.1
Standard deviation 0.86
Values 21 19
[174]
THLE TERF1
Mean 11.9
Standard deviation 0.88
Values 11 13
[175]
liver TERF1
Mean 6.49
Standard deviation 1.9
Values 8.7 6.1 6.9 4.2
[176]
ref_hepatocyte ANKRD28
Mean 4.42
Standard deviation 1.5
Values 4.6 6.5 3.6 2.5 4.9
[177]
HepG2 ANKRD28
Mean 10.7
Standard deviation 1.5
Values 9.7 12
[178]
HepG2.C3A ANKRD28
Mean 20.6
Standard deviation 1.1
Values 20 21
[179]
HuH.7 ANKRD28
Mean 27.6
Standard deviation 4.1
Values 32 26 24
[180]
SNU475 ANKRD28
Mean 9.89
Standard deviation 2.6
Values 8 12
[181]
THLE ANKRD28
Mean 23.6
Standard deviation 0.36
Values 23 24
[182]
liver ANKRD28
Mean 23.8
Standard deviation 12
Values 17 39 11 27
[183]
ref_hepatocyte TERF2
Mean 4.13
Standard deviation 0.67
Values 4.9 4.3 4.6 3.7 3.2
[184]
HepG2 TERF2
Mean 11.3
Standard deviation 0.25
Values 11 11
[185]
HepG2.C3A TERF2
Mean 10.1
Standard deviation 0.26
Values 9.9 10
[186]
HuH.7 TERF2
Mean 16.5
Standard deviation 2.9
Values 17 13 19
[187]
SNU475 TERF2
Mean 7.14
Standard deviation 0.058
Values 7.1 7.2
[188]
THLE TERF2
Mean 10.6
Standard deviation 0.15
Values 11 11
[189]
liver TERF2
Mean 4.32
Standard deviation 1.4
Values 6.4 3.6 3.6 3.7
[190]
ref_hepatocyte SHQ1
Mean 3.82
Standard deviation 1.8
Values 4.8 6.2 3.9 1.7 2.5
[191]
HepG2 SHQ1
Mean 8.25
Standard deviation 1.2
Values 7.4 9.1
[192]
HepG2.C3A SHQ1
Mean 6.92
Standard deviation 2.2
Values 5.4 8.5
[193]
HuH.7 SHQ1
Mean 4.62
Standard deviation 0.69
Values 5.4 4 4.5
[194]
SNU475 SHQ1
Mean 4.84
Standard deviation 1.1
Values 4 5.6
[195]
THLE SHQ1
Mean 11.8
Standard deviation 3
Values 9.7 14
[196]
liver SHQ1
Mean 6.48
Standard deviation 1.1
Values 6.8 6.4 7.8 5
[197]
ref_hepatocyte CCNA2
Mean 3.28
Standard deviation 3.7
Values 7 7.5 0.2 1.1 0.57
[198]
HepG2 CCNA2
Mean 33.4
Standard deviation 16
Values 22 44
[199]
HepG2.C3A CCNA2
Mean 60.1
Standard deviation 42
Values 30 90
[200]
HuH.7 CCNA2
Mean 36.5
Standard deviation 15
Values 47 20 43
[201]
SNU475 CCNA2
Mean 24.1
Standard deviation 0.4
Values 24 24
[202]
THLE CCNA2
Mean 71
Standard deviation 9.4
Values 64 78
[203]
liver CCNA2
Mean 1.99
Standard deviation 1.7
Values 0.85 3.4 3.5 0.21
[204]
ref_hepatocyte RFC3
Mean 3.17
Standard deviation 3.1
Values 6.3 6.7 1.4 0.35 1.1
[205]
HepG2 RFC3
Mean 15.8
Standard deviation 7.8
Values 10 21
[206]
HepG2.C3A RFC3
Mean 25.6
Standard deviation 17
Values 14 37
[207]
HuH.7 RFC3
Mean 27.1
Standard deviation 12
Values 35 14 33
[208]
SNU475 RFC3
Mean 13.8
Standard deviation 3.5
Values 11 16
[209]
THLE RFC3
Mean 23.5
Standard deviation 5.4
Values 20 27
[210]
liver RFC3
Mean 2.46
Standard deviation 0.85
Values 2 2.9 3.4 1.5
[211]
ref_hepatocyte LIG1
Mean 3.08
Standard deviation 2.7
Values 7.4 3.8 0.82 2.1 1.3
[212]
HepG2 LIG1
Mean 21.1
Standard deviation 4.6
Values 18 24
[213]
HepG2.C3A LIG1
Mean 19
Standard deviation 5
Values 15 23
[214]
HuH.7 LIG1
Mean 28.4
Standard deviation 13
Values 35 13 37
[215]
SNU475 LIG1
Mean 8.05
Standard deviation 0.33
Values 8.3 7.8
[216]
THLE LIG1
Mean 15.1
Standard deviation 4
Values 12 18
[217]
liver LIG1
Mean 3.39
Standard deviation 0.66
Values 3.3 3.3 4.3 2.7
[218]
ref_hepatocyte POLA2
Mean 2.46
Standard deviation 0.96
Values 1.8 2.8 3.9 2.3 1.5
[219]
HepG2 POLA2
Mean 8.49
Standard deviation 2.2
Values 6.9 10
[220]
HepG2.C3A POLA2
Mean 5.87
Standard deviation 3.6
Values 3.3 8.4
[221]
HuH.7 POLA2
Mean 8.32
Standard deviation 5.1
Values 11 2.5 11
[222]
SNU475 POLA2
Mean 12.9
Standard deviation 3.1
Values 11 15
[223]
THLE POLA2
Mean 17.9
Standard deviation 4
Values 15 21
[224]
liver POLA2
Mean 1.96
Standard deviation 0.6
Values 1.2 1.9 2.6 2.2
[225]
ref_hepatocyte PRIM1
Mean 2.43
Standard deviation 1.4
Values 4.4 2.6 0.57 2.6 1.9
[226]
HepG2 PRIM1
Mean 8.54
Standard deviation 0.87
Values 7.9 9.2
[227]
HepG2.C3A PRIM1
Mean 19.1
Standard deviation 8.1
Values 13 25
[228]
HuH.7 PRIM1
Mean 23.1
Standard deviation 6.2
Values 27 16 26
[229]
SNU475 PRIM1
Mean 9.98
Standard deviation 3.1
Values 7.8 12
[230]
THLE PRIM1
Mean 16.8
Standard deviation 2.1
Values 15 18
[231]
liver PRIM1
Mean 1.84
Standard deviation 0.34
Values 2.1 1.6 2.1 1.5
[232]
ref_hepatocyte POLD1
Mean 2.41
Standard deviation 0.8
Values 2 3.5 2.7 2.4 1.4
[233]
HepG2 POLD1
Mean 19.3
Standard deviation 1.9
Values 21 18
[234]
HepG2.C3A POLD1
Mean 20.1
Standard deviation 2.3
Values 18 22
[235]
HuH.7 POLD1
Mean 34
Standard deviation 15
Values 42 16 44
[236]
SNU475 POLD1
Mean 15.6
Standard deviation 2.9
Values 14 18
[237]
THLE POLD1
Mean 29.7
Standard deviation 2.6
Values 28 32
[238]
liver POLD1
Mean 5.43
Standard deviation 0.68
Values 6.2 4.7 5.8 5.1
[239]
ref_hepatocyte PRIM2
Mean 2.32
Standard deviation 2.3
Values 6.1 2.9 0.46 1.4 0.78
[240]
HepG2 PRIM2
Mean 12.4
Standard deviation 3.6
Values 9.9 15
[241]
HepG2.C3A PRIM2
Mean 9.66
Standard deviation 4.4
Values 6.5 13
[242]
HuH.7 PRIM2
Mean 7.1
Standard deviation 1.5
Values 7.8 5.4 8.1
[243]
SNU475 PRIM2
Mean 9.65
Standard deviation 1.6
Values 8.5 11
[244]
THLE PRIM2
Mean 12.8
Standard deviation 1.5
Values 12 14
[245]
liver PRIM2
Mean 1.1
Standard deviation 0.41
Values 0.68 1.5 0.82 1.4
[246]
ref_hepatocyte POT1
Mean 2.27
Standard deviation 0.82
Values 3.2 2.4 0.96 2.2 2.5
[247]
HepG2 POT1
Mean 5.04
Standard deviation 1.2
Values 4.2 5.9
[248]
HepG2.C3A POT1
Mean 10.9
Standard deviation 2
Values 9.5 12
[249]
HuH.7 POT1
Mean 12.4
Standard deviation 0.67
Values 12 13 12
[250]
SNU475 POT1
Mean 14.1
Standard deviation 0.62
Values 14 15
[251]
THLE POT1
Mean 13.4
Standard deviation 2.1
Values 15 12
[252]
liver POT1
Mean 5.58
Standard deviation 1.5
Values 4.5 7.1 6.7 4.1
[253]
ref_hepatocyte WRAP53
Mean 2.2
Standard deviation 2.1
Values 0.84 0.88 5.8 1.7 1.8
[254]
HepG2 WRAP53
Mean 9.4
Standard deviation 1
Values 8.7 10
[255]
HepG2.C3A WRAP53
Mean 6.34
Standard deviation 3.1
Values 4.2 8.5
[256]
HuH.7 WRAP53
Mean 11.1
Standard deviation 4
Values 13 6.6 14
[257]
SNU475 WRAP53
Mean 4.75
Standard deviation 0.87
Values 4.1 5.4
[258]
THLE WRAP53
Mean 9.78
Standard deviation 2.1
Values 8.3 11
[259]
liver WRAP53
Mean 1.16
Standard deviation 0.7
Values 1.8 0.41 1.7 0.73
[260]
ref_hepatocyte ACD
Mean 2.1
Standard deviation 0.79
Values 3 2.7 2.2 1.6 1
[261]
HepG2 ACD
Mean 15.1
Standard deviation 1.5
Values 16 14
[262]
HepG2.C3A ACD
Mean 16.2
Standard deviation 0.61
Values 16 17
[263]
HuH.7 ACD
Mean 13.3
Standard deviation 3.4
Values 15 9.4 15
[264]
SNU475 ACD
Mean 6.51
Standard deviation 0.88
Values 5.9 7.1
[265]
THLE ACD
Mean 12.1
Standard deviation 0.43
Values 12 12
[266]
liver ACD
Mean 1.85
Standard deviation 1.2
Values 3.2 0.64 2.5 1
[267]
ref_hepatocyte DSCC1
Mean 1.52
Standard deviation 1.3
Values 2 3.6 0.69 0.56 0.78
[268]
HepG2 DSCC1
Mean 5.65
Standard deviation 2.9
Values 3.6 7.7
[269]
HepG2.C3A DSCC1
Mean 8.23
Standard deviation 5.3
Values 4.5 12
[270]
HuH.7 DSCC1
Mean 14.4
Standard deviation 6.4
Values 19 7.1 18
[271]
SNU475 DSCC1
Mean 9.14
Standard deviation 2.1
Values 7.6 11
[272]
THLE DSCC1
Mean 7.24
Standard deviation 1.1
Values 6.5 8
[273]
liver DSCC1
Mean 0.599
Standard deviation 0.23
Values 0.63 0.7 0.8 0.26
[274]
ref_hepatocyte POLD3
Mean 1.46
Standard deviation 0.56
Values 1.9 1.9 1 1.8 0.71
[275]
HepG2 POLD3
Mean 7.29
Standard deviation 0.95
Values 6.6 8
[276]
HepG2.C3A POLD3
Mean 5.94
Standard deviation 4
Values 3.1 8.8
[277]
HuH.7 POLD3
Mean 11.2
Standard deviation 6.1
Values 15 4.1 14
[278]
SNU475 POLD3
Mean 11.6
Standard deviation 3.7
Values 9 14
[279]
THLE POLD3
Mean 18.3
Standard deviation 1.6
Values 17 19
[280]
liver POLD3
Mean 4.11
Standard deviation 1.1
Values 3.6 4.3 5.6 3
[281]
ref_hepatocyte RTEL1
Mean 1.41
Standard deviation 0.26
Values 1.7 1.2 1.4 1.6 1.1
[282]
HepG2 RTEL1
Mean 0.952
Standard deviation 0.24
Values 0.79 1.1
[283]
HepG2.C3A RTEL1
Mean 1.86
Standard deviation 0.37
Values 2.1 1.6
[284]
HuH.7 RTEL1
Mean 0.508
Standard deviation 0.12
Values 0.61 0.37 0.54
[285]
SNU475 RTEL1
Mean 0.529
Standard deviation 0.019
Values 0.51 0.54
[286]
THLE RTEL1
Mean 0.883
Standard deviation 0.16
Values 0.99 0.77
[287]
liver RTEL1
Mean 0.636
Standard deviation 0.18
Values 0.87 0.47 0.51 0.69
[288]
ref_hepatocyte WRN
Mean 1.33
Standard deviation 0.66
Values 1.8 1.8 1.8 0.68 0.54
[289]
HepG2 WRN
Mean 4.47
Standard deviation 1.6
Values 3.3 5.6
[290]
HepG2.C3A WRN
Mean 11
Standard deviation 2.1
Values 9.5 12
[291]
HuH.7 WRN
Mean 40.4
Standard deviation 6.8
Values 43 46 33
[292]
SNU475 WRN
Mean 7.93
Standard deviation 0.72
Values 8.4 7.4
[293]
THLE WRN
Mean 7.81
Standard deviation 1.9
Values 9.2 6.5
[294]
liver WRN
Mean 7.39
Standard deviation 3.4
Values 4.3 10 4.7 10
[295]
ref_hepatocyte CTC1
Mean 1.16
Standard deviation 0.53
Values 1.5 0.59 1.9 0.9 0.9
[296]
HepG2 CTC1
Mean 10
Standard deviation 1.9
Values 11 8.6
[297]
HepG2.C3A CTC1
Mean 10.2
Standard deviation 0.91
Values 11 9.6
[298]
HuH.7 CTC1
Mean 19.2
Standard deviation 1.9
Values 21 17 19
[299]
SNU475 CTC1
Mean 7.04
Standard deviation 1.1
Values 7.8 6.3
[300]
THLE CTC1
Mean 8.04
Standard deviation 0.32
Values 8.3 7.8
[301]
liver CTC1
Mean 6.96
Standard deviation 0.61
Values 7.1 6.1 7.4 7.2
[302]
ref_hepatocyte POLA1
Mean 0.985
Standard deviation 0.81
Values 1.8 2 0.27 0.52 0.41
[303]
HepG2 POLA1
Mean 8.75
Standard deviation 4.7
Values 5.4 12
[304]
HepG2.C3A POLA1
Mean 8.42
Standard deviation 3.5
Values 5.9 11
[305]
HuH.7 POLA1
Mean 11.9
Standard deviation 5.3
Values 17 6.3 13
[306]
SNU475 POLA1
Mean 14.3
Standard deviation 5.6
Values 10 18
[307]
THLE POLA1
Mean 15.7
Standard deviation 1.1
Values 15 17
[308]
liver POLA1
Mean 4.45
Standard deviation 2.4
Values 1.9 7.6 3.5 4.8
[309]
ref_hepatocyte CHTF18
Mean 0.819
Standard deviation 0.21
Values 0.8 0.76 1.2 0.72 0.64
[310]
HepG2 CHTF18
Mean 4.8
Standard deviation 0.4
Values 4.5 5.1
[311]
HepG2.C3A CHTF18
Mean 7.62
Standard deviation 2
Values 6.2 9
[312]
HuH.7 CHTF18
Mean 11
Standard deviation 6
Values 12 4.6 16
[313]
SNU475 CHTF18
Mean 3.83
Standard deviation 0.59
Values 3.4 4.2
[314]
THLE CHTF18
Mean 7.56
Standard deviation 0.8
Values 8.1 7
[315]
liver CHTF18
Mean 0.964
Standard deviation 0.13
Values 1 0.86 1.1 0.86
[316]
ref_hepatocyte DNA2
Mean 0.686
Standard deviation 0.42
Values 1.2 1.1 0.52 0.36 0.28
[317]
HepG2 DNA2
Mean 5.13
Standard deviation 3.4
Values 2.7 7.6
[318]
HepG2.C3A DNA2
Mean 15.6
Standard deviation 12
Values 7.4 24
[319]
HuH.7 DNA2
Mean 8.62
Standard deviation 3.7
Values 11 4.3 11
[320]
SNU475 DNA2
Mean 7.89
Standard deviation 1.4
Values 6.9 8.9
[321]
THLE DNA2
Mean 7
Standard deviation 0.46
Values 6.7 7.3
[322]
liver DNA2
Mean 2.88
Standard deviation 1.1
Values 2.8 3.6 1.3 3.8
[323]
ref_hepatocyte BLM
Mean 0.47
Standard deviation 0.48
Values 1.3 0.54 0.16 0.18 0.18
[324]
HepG2 BLM
Mean 3.02
Standard deviation 1.6
Values 1.9 4.1
[325]
HepG2.C3A BLM
Mean 6.88
Standard deviation 4.6
Values 3.6 10
[326]
HuH.7 BLM
Mean 11.6
Standard deviation 6.1
Values 16 4.6 14
[327]
SNU475 BLM
Mean 6.41
Standard deviation 2.4
Values 4.7 8.1
[328]
THLE BLM
Mean 7.59
Standard deviation 0.46
Values 7.3 7.9
[329]
liver BLM
Mean 0.512
Standard deviation 0.32
Values 0.38 0.87 0.67 0.13
[330]
ref_hepatocyte PIF1
Mean 0.247
Standard deviation 0.11
Values 0.27 0.4 0.26 0.1 0.21
[331]
HepG2 PIF1
Mean 2.19
Standard deviation 0.27
Values 2 2.4
[332]
HepG2.C3A PIF1
Mean 7.28
Standard deviation 1.3
Values 6.4 8.2
[333]
HuH.7 PIF1
Mean 7.23
Standard deviation 4.1
Values 6.5 3.6 12
[334]
SNU475 PIF1
Mean 2.8
Standard deviation 0.4
Values 3.1 2.5
[335]
THLE PIF1
Mean 5.17
Standard deviation 0.74
Values 4.6 5.7
[336]
liver PIF1
Mean 0.307
Standard deviation 0.13
Values 0.26 0.5 0.26 0.21
[337]
ref_hepatocyte TERT
Mean 0.123
Standard deviation 0.19
Values 0.44 0 0.18 0 0
[338]
HepG2 TERT
Mean 3.05
Standard deviation 0.27
Values 2.9 3.2
[339]
HepG2.C3A TERT
Mean 2.3
Standard deviation 0.4
Values 2 2.6
[340]
HuH.7 TERT
Mean 4.23
Standard deviation 2.5
Values 5.5 1.4 5.9
[341]
SNU475 TERT
Mean 1.03
Standard deviation 0.19
Values 0.89 1.2
[342]
THLE TERT
Mean 0.0175
Standard deviation 0.017
Values 0.03 0.0053
[343]
liver TERT
Mean 0.0118
Standard deviation 0.024
Values 0.047 0 0 0
[344]
ref_hepatocyte CCNA1
Mean 0.0259
Standard deviation 0.058
Values 0.13 0 0 0 0
[345]
HepG2 CCNA1
Mean 0
Standard deviation 0
Values 0 0
[346]
HepG2.C3A CCNA1
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[347]
HuH.7 CCNA1
Mean 0
Standard deviation 0
Values 0 0 0
[348]
SNU475 CCNA1
Mean 0.0274
Standard deviation 0.026
Values 0.0093 0.046
[349]
THLE CCNA1
Mean 5.22
Standard deviation 2.3
Values 3.6 6.9
[350]
liver CCNA1
Mean 0
Standard deviation 0
Values 0 0 0 0
[351]
ref_hepatocyte STN1
Missing
[352]
HepG2 STN1
Missing
[353]
HepG2.C3A STN1
Missing
[354]
HuH.7 STN1
Missing
[355]
SNU475 STN1
Missing
[356]
THLE STN1
Missing
[357]
liver STN1
Missing