REACTOME_ESTROGEN_BIOSYNTHESIS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 HSD17B11 Estradiol 17-beta-dehydrogenase 11 [1] 0.22[2] 0.40[3] 0.60[4] 0.59[5] 0.78[6] 0.45[7]
2 HSD17B2 Estradiol 17-beta-dehydrogenase 2 [8] -0.88[9] -0.73[10] -0.94[11] -6.80[12] -4.30[13] -0.12[14]
3 HSD17B14 17-beta-hydroxysteroid dehydrogenase 14 [15] -3.21[16] -8.12[17] -1.11[18] -1.65[19] -3.21[20] -2.81[21]
4 HSD17B1 Estradiol 17-beta-dehydrogenase 1 [22] 2.49[23] 1.84[24] 1.45[25] 2.84[26] 3.28[27] 0.01[28]
5 CYP19A1 Aromatase [29] 3.62[30] 3.34[31] -2.90[32] 1.23[33] -0.52[34] -5.89[35]
6 AKR1B15 Aldo-keto reductase family 1 member B15 [36] 2.12[37] 0.02[38] -4.13[39] 4.24[40] -1.32[41] -2.25[42]
[1]
ref_hepatocyte HSD17B11
Mean 49.3
Standard deviation 28
Values 42 42 11 65 86
[2]
HepG2 HSD17B11
Mean 39.3
Standard deviation 1.7
Values 38 41
[3]
HepG2.C3A HSD17B11
Mean 97.5
Standard deviation 3.8
Values 1e+02 95
[4]
HuH.7 HSD17B11
Mean 92.5
Standard deviation 17
Values 86 1.1e+02 80
[5]
SNU475 HSD17B11
Mean 18.4
Standard deviation 2.6
Values 20 17
[6]
THLE HSD17B11
Mean 14.5
Standard deviation 3.3
Values 12 17
[7]
liver HSD17B11
Mean 70.5
Standard deviation 33
Values 1.1e+02 51 78 38
[8]
ref_hepatocyte HSD17B2
Mean 38.5
Standard deviation 40
Values 8.2 9.4 11 81 83
[9]
HepG2 HSD17B2
Mean 14.3
Standard deviation 1.8
Values 16 13
[10]
HepG2.C3A HSD17B2
Mean 34.6
Standard deviation 18
Values 47 22
[11]
HuH.7 HSD17B2
Mean 24.8
Standard deviation 4.5
Values 23 30 22
[12]
SNU475 HSD17B2
Mean 0.0863
Standard deviation 0.029
Values 0.11 0.066
[13]
THLE HSD17B2
Mean 0.334
Standard deviation 0.16
Values 0.45 0.22
[14]
liver HSD17B2
Mean 36.9
Standard deviation 25
Values 51 24 64 8.9
[15]
ref_hepatocyte HSD17B14
Mean 15.8
Standard deviation 23
Values 0.96 0.86 0.77 22 54
[16]
HepG2 HSD17B14
Mean 1.17
Standard deviation 0.26
Values 1.4 0.98
[17]
HepG2.C3A HSD17B14
Mean 0.0846
Standard deviation 0.059
Values 0.13 0.043
[18]
HuH.7 HSD17B14
Mean 9.1
Standard deviation 5.6
Values 4.8 15 7.1
[19]
SNU475 HSD17B14
Mean 1.25
Standard deviation 0.27
Values 1.4 1.1
[20]
THLE HSD17B14
Mean 0.293
Standard deviation 0.046
Values 0.33 0.26
[21]
liver HSD17B14
Mean 2.35
Standard deviation 2.4
Values 5.8 0.54 2.3 0.81
[22]
ref_hepatocyte HSD17B1
Mean 1.84
Standard deviation 1.8
Values 0 0 3.8 3.6 1.8
[23]
HepG2 HSD17B1
Mean 7.09
Standard deviation 0.31
Values 7.3 6.9
[24]
HepG2.C3A HSD17B1
Mean 9.86
Standard deviation 0.69
Values 10 9.4
[25]
HuH.7 HSD17B1
Mean 6.23
Standard deviation 0.45
Values 6 5.9 6.7
[26]
SNU475 HSD17B1
Mean 3.28
Standard deviation 0.071
Values 3.3 3.2
[27]
THLE HSD17B1
Mean 3.07
Standard deviation 0.04
Values 3.1 3
[28]
liver HSD17B1
Mean 1.94
Standard deviation 0.82
Values 2.9 0.98 2.1 1.7
[29]
ref_hepatocyte CYP19A1
Mean 1.13
Standard deviation 2.3
Values 5.3 0.08 0.28 0 0
[30]
HepG2 CYP19A1
Mean 9.51
Standard deviation 0.87
Values 8.9 10
[31]
HepG2.C3A CYP19A1
Mean 17.1
Standard deviation 5.6
Values 21 13
[32]
HuH.7 CYP19A1
Mean 0.188
Standard deviation 0.27
Values 0.016 0.5 0.047
[33]
SNU475 CYP19A1
Mean 0.66
Standard deviation 0.58
Values 0.25 1.1
[34]
THLE CYP19A1
Mean 0.135
Standard deviation 0.018
Values 0.15 0.12
[35]
liver CYP19A1
Mean 0.0199
Standard deviation 0.04
Values 0 0 0 0.079
[36]
ref_hepatocyte AKR1B15
Mean 0.629
Standard deviation 0.82
Values 0 1.2 0 1.8 0.15
[37]
HepG2 AKR1B15
Mean 1.87
Standard deviation 1.3
Values 2.8 0.93
[38]
HepG2.C3A AKR1B15
Mean 0.952
Standard deviation 0.84
Values 0.36 1.5
[39]
HuH.7 AKR1B15
Mean 0.0445
Standard deviation 0.059
Values 0.0082 0.013 0.11
[40]
SNU475 AKR1B15
Mean 2.97
Standard deviation 0.57
Values 3.4 2.6
[41]
THLE AKR1B15
Mean 0.0432
Standard deviation 0.031
Values 0.065 0.021
[42]
liver AKR1B15
Mean 0.138
Standard deviation 0.19
Values 0 0.11 0.41 0.026