REACTOME_ER_QUALITY_CONTROL_COMPARTMENT_ERQC Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 UBB Polyubiquitin-B [1] -0.52[2] -0.75[3] -0.74[4] -0.67[5] -0.43[6] -0.76[7]
2 RPS27A Ubiquitin-40S ribosomal protein S27a [8] [9] [10] [11] [12] [13] [14]
3 UBC Polyubiquitin-C [15] -0.08[16] 0.00[17] -0.37[18] 0.19[19] -0.05[20] -0.31[21]
4 OS9 Protein OS-9 [22] 0.92[23] 1.30[24] 0.91[25] 0.50[26] 0.52[27] 1.08[28]
5 UBA52 Ubiquitin-60S ribosomal protein L40 [29] 2.36[30] 2.23[31] 3.14[32] 1.58[33] 2.18[34] 0.46[35]
6 RNF5 E3 ubiquitin-protein ligase RNF5 [36] -8.68[37] -8.04[38] -7.29[39] -8.71[40] -10.23[41] -9.07[42]
7 DERL2 Derlin-2 [43] -0.54[44] 0.07[45] -0.59[46] 0.41[47] -0.07[48] -0.06[49]
8 AMFR E3 ubiquitin-protein ligase AMFR [50] 2.12[51] 1.51[52] 0.56[53] 1.61[54] 1.83[55] 2.72[56]
9 SYVN1 E3 ubiquitin-protein ligase synoviolin [57] 0.71[58] 1.01[59] 0.47[60] 0.72[61] 0.62[62] 1.53[63]
10 SEL1L Protein sel-1 homolog 1 [64] 2.00[65] 2.40[66] 2.19[67] 3.08[68] 2.55[69] 3.94[70]
11 EDEM2 ER degradation-enhancing alpha-mannosidase-like protein 2 [71] 2.32[72] 2.04[73] 0.67[74] 1.63[75] 0.41[76] 0.80[77]
12 MAN1B1 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 2.47[78] 2.09[79] 2.29[80] 2.28[81] 1.81[82] 1.02[83]
13 RNF103 E3 ubiquitin-protein ligase RNF103 [84] 0.58[85] 1.58[86] 1.46[87] 1.44[88] 0.86[89] 1.45[90]
14 RNF185 E3 ubiquitin-protein ligase RNF185 [91] 1.65[92] 1.45[93] 1.78[94] 1.70[95] 1.35[96] 1.95[97]
15 EDEM1 ER degradation-enhancing alpha-mannosidase-like protein 1 [98] 2.66[99] 2.85[100] 2.85[101] 2.23[102] 3.37[103] 4.28[104]
16 RNF139 E3 ubiquitin-protein ligase RNF139 [105] 1.80[106] 2.09[107] 1.69[108] 2.44[109] 1.68[110] 1.36[111]
17 EDEM3 ER degradation-enhancing alpha-mannosidase-like protein 3 [112] 1.33[113] 3.03[114] 3.89[115] 4.00[116] 3.68[117] 4.22[118]
18 UGGT1 UDP-glucose:glycoprotein glucosyltransferase 1 [119] 4.93[120] 4.71[121] 4.78[122] 5.11[123] 4.93[124] 4.69[125]
19 UGGT2 UDP-glucose:glycoprotein glucosyltransferase 2 [126] 2.92[127] 3.89[128] 2.37[129] 3.22[130] 4.01[131] 3.12[132]
20 TRIM13 E3 ubiquitin-protein ligase TRIM13 [133] 3.72[134] 4.22[135] 3.94[136] 3.86[137] 3.82[138] 4.06[139]
21 MARCHF6 [140] [141] [142] [143] [144] [145] [146]
[1]
ref_hepatocyte UBB
Mean 764
Standard deviation 4.8e+02
Values 3.8e+02 3.5e+02 5.3e+02 1.2e+03 1.3e+03
[2]
HepG2 UBB
Mean 368
Standard deviation 39
Values 4e+02 3.4e+02
[3]
HepG2.C3A UBB
Mean 285
Standard deviation 14
Values 2.8e+02 3e+02
[4]
HuH.7 UBB
Mean 304
Standard deviation 40
Values 2.9e+02 2.7e+02 3.5e+02
[5]
SNU475 UBB
Mean 204
Standard deviation 3.3
Values 2.1e+02 2e+02
[6]
THLE UBB
Mean 315
Standard deviation 34
Values 2.9e+02 3.4e+02
[7]
liver UBB
Mean 296
Standard deviation 1.3e+02
Values 4.3e+02 2.1e+02 3.9e+02 1.5e+02
[8]
ref_hepatocyte RPS27A
Mean 499
Standard deviation 2.2e+02
Values 6.6e+02 6.1e+02 1.7e+02 6.8e+02 3.8e+02
[9]
HepG2 RPS27A
Missing
[10]
HepG2.C3A RPS27A
Missing
[11]
HuH.7 RPS27A
Missing
[12]
SNU475 RPS27A
Missing
[13]
THLE RPS27A
Missing
[14]
liver RPS27A
Missing
[15]
ref_hepatocyte UBC
Mean 480
Standard deviation 2.8e+02
Values 1.8e+02 3.5e+02 9.1e+02 5.8e+02 3.8e+02
[16]
HepG2 UBC
Mean 314
Standard deviation 38
Values 3.4e+02 2.9e+02
[17]
HepG2.C3A UBC
Mean 302
Standard deviation 41
Values 3.3e+02 2.7e+02
[18]
HuH.7 UBC
Mean 246
Standard deviation 64
Values 2.4e+02 3.1e+02 1.9e+02
[19]
SNU475 UBC
Mean 232
Standard deviation 63
Values 2.8e+02 1.9e+02
[20]
THLE UBC
Mean 257
Standard deviation 41
Values 2.3e+02 2.9e+02
[21]
liver UBC
Mean 254
Standard deviation 78
Values 2.2e+02 3.1e+02 3.3e+02 1.6e+02
[22]
ref_hepatocyte OS9
Mean 87.3
Standard deviation 51
Values 86 52 24 1.3e+02 1.4e+02
[23]
HepG2 OS9
Mean 114
Standard deviation 14
Values 1.2e+02 1e+02
[24]
HepG2.C3A OS9
Mean 135
Standard deviation 40
Values 1.6e+02 1.1e+02
[25]
HuH.7 OS9
Mean 109
Standard deviation 15
Values 94 1.2e+02 1.1e+02
[26]
SNU475 OS9
Mean 52.4
Standard deviation 4.7
Values 56 49
[27]
THLE OS9
Mean 69.2
Standard deviation 8.7
Values 63 75
[28]
liver OS9
Mean 121
Standard deviation 20
Values 1.3e+02 1.1e+02 1.4e+02 1e+02
[29]
ref_hepatocyte UBA52
Mean 57.3
Standard deviation 43
Values 14 23 49 1.2e+02 81
[30]
HepG2 UBA52
Mean 203
Standard deviation 20
Values 2.2e+02 1.9e+02
[31]
HepG2.C3A UBA52
Mean 169
Standard deviation 3.3
Values 1.7e+02 1.7e+02
[32]
HuH.7 UBA52
Mean 334
Standard deviation 46
Values 3.4e+02 2.8e+02 3.7e+02
[33]
SNU475 UBA52
Mean 72.9
Standard deviation 11
Values 65 81
[34]
THLE UBA52
Mean 144
Standard deviation 15
Values 1.3e+02 1.5e+02
[35]
liver UBA52
Mean 51.7
Standard deviation 26
Values 79 32 68 28
[36]
ref_hepatocyte RNF5
Mean 46.7
Standard deviation 24
Values 42 19 30 66 77
[37]
HepG2 RNF5
Mean 0.0788
Standard deviation 0.075
Values 0.13 0.026
[38]
HepG2.C3A RNF5
Mean 0.111
Standard deviation 0.021
Values 0.13 0.097
[39]
HuH.7 RNF5
Mean 0.197
Standard deviation 0.031
Values 0.23 0.19 0.17
[40]
SNU475 RNF5
Mean 0.0475
Standard deviation 0.031
Values 0.07 0.025
[41]
THLE RNF5
Mean 0.0216
Standard deviation 0.022
Values 0.0059 0.037
[42]
liver RNF5
Mean 0.0572
Standard deviation 0.099
Values 0.024 0 0.21 0
[43]
ref_hepatocyte DERL2
Mean 27.8
Standard deviation 9.8
Values 20 27 20 44 28
[44]
HepG2 DERL2
Mean 13.1
Standard deviation 3.2
Values 11 15
[45]
HepG2.C3A DERL2
Mean 18.3
Standard deviation 2.5
Values 17 20
[46]
HuH.7 DERL2
Mean 12.2
Standard deviation 0.88
Values 11 12 13
[47]
SNU475 DERL2
Mean 15.6
Standard deviation 3.9
Values 18 13
[48]
THLE DERL2
Mean 14.6
Standard deviation 2.6
Values 13 16
[49]
liver DERL2
Mean 17.5
Standard deviation 12
Values 23 8.3 31 7.3
[50]
ref_hepatocyte AMFR
Mean 23.1
Standard deviation 6
Values 19 23 16 32 25
[51]
HepG2 AMFR
Mean 69.4
Standard deviation 13
Values 79 60
[52]
HepG2.C3A AMFR
Mean 41.4
Standard deviation 7.9
Values 47 36
[53]
HuH.7 AMFR
Mean 22.7
Standard deviation 2.5
Values 21 26 21
[54]
SNU475 AMFR
Mean 30
Standard deviation 3.7
Values 33 27
[55]
THLE AMFR
Mean 45.8
Standard deviation 1.6
Values 47 45
[56]
liver AMFR
Mean 100
Standard deviation 51
Values 81 82 63 1.8e+02
[57]
ref_hepatocyte SYVN1
Mean 20.3
Standard deviation 18
Values 2.3 2.6 24 44 29
[58]
HepG2 SYVN1
Mean 22.9
Standard deviation 2.1
Values 24 21
[59]
HepG2.C3A SYVN1
Mean 25.6
Standard deviation 13
Values 35 16
[60]
HuH.7 SYVN1
Mean 18.6
Standard deviation 3.1
Values 16 22 17
[61]
SNU475 SYVN1
Mean 14.1
Standard deviation 1.9
Values 15 13
[62]
THLE SYVN1
Mean 17.3
Standard deviation 0.72
Values 17 18
[63]
liver SYVN1
Mean 38.6
Standard deviation 9.3
Values 43 26 48 38
[64]
ref_hepatocyte SEL1L
Mean 15.3
Standard deviation 6
Values 6.6 15 14 23 17
[65]
HepG2 SEL1L
Mean 42.2
Standard deviation 13
Values 33 51
[66]
HepG2.C3A SEL1L
Mean 50.8
Standard deviation 5.2
Values 47 54
[67]
HuH.7 SEL1L
Mean 46.1
Standard deviation 17
Values 45 64 30
[68]
SNU475 SEL1L
Mean 54.8
Standard deviation 20
Values 69 40
[69]
THLE SEL1L
Mean 49.6
Standard deviation 0.3
Values 49 50
[70]
liver SEL1L
Mean 154
Standard deviation 39
Values 1.1e+02 2e+02 1.4e+02 1.7e+02
[71]
ref_hepatocyte EDEM2
Mean 13.9
Standard deviation 4.1
Values 15 14 9.2 20 12
[72]
HepG2 EDEM2
Mean 48.2
Standard deviation 1.9
Values 50 47
[73]
HepG2.C3A EDEM2
Mean 36.1
Standard deviation 6.9
Values 41 31
[74]
HuH.7 EDEM2
Mean 14.7
Standard deviation 1.3
Values 14 14 16
[75]
SNU475 EDEM2
Mean 18.3
Standard deviation 4.2
Values 21 15
[76]
THLE EDEM2
Mean 10.3
Standard deviation 1.2
Values 9.4 11
[77]
liver EDEM2
Mean 15.9
Standard deviation 4.7
Values 20 11 20 13
[78]
ref_hepatocyte MAN1B1
Mean 12.6
Standard deviation 4
Values 10 18 7.3 15 13
[79]
HepG2 MAN1B1
Mean 48
Standard deviation 5.2
Values 52 44
[80]
HepG2.C3A MAN1B1
Mean 33.8
Standard deviation 8.4
Values 40 28
[81]
HuH.7 MAN1B1
Mean 40.7
Standard deviation 9.9
Values 44 30 48
[82]
SNU475 MAN1B1
Mean 25.9
Standard deviation 7
Values 31 21
[83]
THLE MAN1B1
Mean 24.4
Standard deviation 7.8
Values 19 30
[84]
liver MAN1B1
Mean 16.8
Standard deviation 4.7
Values 18 13 23 13
[85]
ref_hepatocyte RNF103
Mean 11.8
Standard deviation 2.6
Values 13 10 8.7 12 16
[86]
HepG2 RNF103
Mean 12.2
Standard deviation 0.93
Values 12 13
[87]
HepG2.C3A RNF103
Mean 22.2
Standard deviation 5.1
Values 26 19
[88]
HuH.7 RNF103
Mean 21.6
Standard deviation 6.5
Values 17 29 19
[89]
SNU475 RNF103
Mean 13.6
Standard deviation 4.2
Values 17 11
[90]
THLE RNF103
Mean 11.9
Standard deviation 1.8
Values 11 13
[91]
liver RNF103
Mean 21.2
Standard deviation 4.1
Values 25 22 16 22
[92]
ref_hepatocyte RNF185
Mean 11.6
Standard deviation 7.6
Values 3.8 5.5 10 22 17
[93]
HepG2 RNF185
Mean 25.1
Standard deviation 0.51
Values 25 25
[94]
HepG2.C3A RNF185
Mean 20
Standard deviation 0.07
Values 20 20
[95]
HuH.7 RNF185
Mean 26.3
Standard deviation 2.2
Values 24 29 26
[96]
SNU475 RNF185
Mean 15.9
Standard deviation 1.4
Values 17 15
[97]
THLE RNF185
Mean 16.4
Standard deviation 3.6
Values 14 19
[98]
liver RNF185
Mean 29.5
Standard deviation 11
Values 34 19 43 22
[99]
ref_hepatocyte EDEM1
Mean 7.75
Standard deviation 3.2
Values 8.7 6.4 3.1 8.7 12
[100]
HepG2 EDEM1
Mean 33.8
Standard deviation 0.56
Values 34 33
[101]
HepG2.C3A EDEM1
Mean 35
Standard deviation 5.1
Values 39 31
[102]
HuH.7 EDEM1
Mean 36.9
Standard deviation 10
Values 32 49 30
[103]
SNU475 EDEM1
Mean 15.4
Standard deviation 2.9
Values 17 13
[104]
THLE EDEM1
Mean 44.5
Standard deviation 7.7
Values 39 50
[105]
liver EDEM1
Mean 98.6
Standard deviation 29
Values 58 1.2e+02 1.1e+02 1e+02
[106]
ref_hepatocyte RNF139
Mean 6.96
Standard deviation 2.2
Values 9.7 7.3 3.8 6 8
[107]
HepG2 RNF139
Mean 16.7
Standard deviation 4.7
Values 13 20
[108]
HepG2.C3A RNF139
Mean 18.7
Standard deviation 1.9
Values 17 20
[109]
HuH.7 RNF139
Mean 14.8
Standard deviation 0.97
Values 14 15 16
[110]
SNU475 RNF139
Mean 16
Standard deviation 1.6
Values 17 15
[111]
THLE RNF139
Mean 12.4
Standard deviation 1.4
Values 11 13
[112]
liver RNF139
Mean 11.7
Standard deviation 0.75
Values 13 12 11 12
[113]
ref_hepatocyte EDEM3
Mean 4.65
Standard deviation 1.5
Values 2.9 5.5 5.2 3.3 6.4
[114]
HepG2 EDEM3
Mean 8.08
Standard deviation 3.4
Values 5.7 10
[115]
HepG2.C3A EDEM3
Mean 23.9
Standard deviation 3.5
Values 26 21
[116]
HuH.7 EDEM3
Mean 45.7
Standard deviation 9
Values 48 54 36
[117]
SNU475 EDEM3
Mean 31.5
Standard deviation 3.9
Values 34 29
[118]
THLE EDEM3
Mean 33.1
Standard deviation 2
Values 32 34
[119]
liver EDEM3
Mean 56.9
Standard deviation 24
Values 29 86 48 64
[120]
ref_hepatocyte UGGT1
Mean 4.26
Standard deviation 2.2
Values 7.7 3.7 1.9 4.7 3.3
[121]
HepG2 UGGT1
Mean 89.9
Standard deviation 3.3
Values 92 88
[122]
HepG2.C3A UGGT1
Mean 70.2
Standard deviation 17
Values 58 82
[123]
HuH.7 UGGT1
Mean 77.7
Standard deviation 27
Values 1.1e+02 68 58
[124]
SNU475 UGGT1
Mean 62.2
Standard deviation 12
Values 71 54
[125]
THLE UGGT1
Mean 72
Standard deviation 17
Values 60 84
[126]
liver UGGT1
Mean 72.1
Standard deviation 48
Values 28 1.1e+02 33 1.1e+02
[127]
ref_hepatocyte UGGT2
Mean 2
Standard deviation 1.8
Values 5.1 1.6 0.58 1.8 0.99
[128]
HepG2 UGGT2
Mean 10.5
Standard deviation 0.67
Values 10 11
[129]
HepG2.C3A UGGT2
Mean 18.6
Standard deviation 1.3
Values 18 20
[130]
HuH.7 UGGT2
Mean 6.83
Standard deviation 0.3
Values 6.8 7.2 6.6
[131]
SNU475 UGGT2
Mean 7.92
Standard deviation 1.4
Values 8.9 6.9
[132]
THLE UGGT2
Mean 17.9
Standard deviation 0.97
Values 19 17
[133]
liver UGGT2
Mean 11.4
Standard deviation 2.4
Values 9.7 15 11 10
[134]
ref_hepatocyte TRIM13
Mean 1.1
Standard deviation 0.34
Values 1.1 1.4 0.52 1.3 1.1
[135]
HepG2 TRIM13
Mean 10
Standard deviation 0.72
Values 9.5 11
[136]
HepG2.C3A TRIM13
Mean 12.9
Standard deviation 0.63
Values 13 12
[137]
HuH.7 TRIM13
Mean 11.2
Standard deviation 3.4
Values 8.5 15 10
[138]
SNU475 TRIM13
Mean 6.76
Standard deviation 0.77
Values 7.3 6.2
[139]
THLE TRIM13
Mean 8.58
Standard deviation 0.025
Values 8.6 8.6
[140]
liver TRIM13
Mean 12
Standard deviation 0.97
Values 13 11 13 11
[141]
ref_hepatocyte MARCHF6
Missing
[142]
HepG2 MARCHF6
Missing
[143]
HepG2.C3A MARCHF6
Missing
[144]
HuH.7 MARCHF6
Missing
[145]
SNU475 MARCHF6
Missing
[146]
THLE MARCHF6
Missing
[147]
liver MARCHF6
Missing