REACTOME_ERYTHROPOIETIN_ACTIVATES_PHOSPHOLIPASE_C_GAMMA_PLCG Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 LYN Tyrosine-protein kinase Lyn [1] -2.29[2] -2.42[3] -1.36[4] -0.13[5] -1.57[6] -1.16[7]
2 EPO Erythropoietin [8] -2.56[9] -0.35[10] -3.67[11] -10.86[12] -12.93[13] -1.19[14]
3 PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 2.06[15] 1.73[16] 1.59[17] 1.63[18] 0.94[19] -0.84[20]
4 IRS2 Insulin receptor substrate 2 [21] -7.08[22] [23] -3.65[24] -1.86[25] 1.78[26] 1.20[27]
5 PLCG2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 -2.71[28] -8.41[29] -0.43[30] -3.92[31] -2.96[32] 1.54[33]
6 JAK2 Tyrosine-protein kinase JAK2 [34] -1.20[35] -1.16[36] -1.07[37] -0.43[38] -0.02[39] 1.53[40]
7 EPOR Erythropoietin receptor [41] -0.16[42] 1.01[43] 2.56[44] -0.02[45] 0.62[46] 1.40[47]
[1]
ref_hepatocyte LYN
Mean 5.33
Standard deviation 4.4
Values 0.29 6.8 12 3.7 3.8
[2]
HepG2 LYN
Mean 6.48
Standard deviation 1
Values 5.8 7.2
[3]
HepG2.C3A LYN
Mean 5.11
Standard deviation 2.1
Values 3.6 6.6
[4]
HuH.7 LYN
Mean 7.08
Standard deviation 0.67
Values 7.4 7.5 6.3
[5]
SNU475 LYN
Mean 20.4
Standard deviation 4.4
Values 17 23
[6]
THLE LYN
Mean 9.65
Standard deviation 1.4
Values 8.7 11
[7]
liver LYN
Mean 7.66
Standard deviation 1.7
Values 7.2 9.4 5.5 8.6
[8]
ref_hepatocyte EPO
Mean 4.3
Standard deviation 5.9
Values 1.1 0 0.32 14 6.2
[9]
HepG2 EPO
Mean 4.34
Standard deviation 2.9
Values 2.3 6.4
[10]
HepG2.C3A EPO
Mean 17.3
Standard deviation 2.6
Values 15 19
[11]
HuH.7 EPO
Mean 1.15
Standard deviation 0.76
Values 0.71 2 0.72
[12]
SNU475 EPO
Mean 0.00971
Standard deviation 0.00061
Values 0.0093 0.01
[13]
THLE EPO
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[14]
liver EPO
Mean 6.05
Standard deviation 8
Values 3.1 2.9 18 0.3
[15]
ref_hepatocyte PLCG1
Mean 3.54
Standard deviation 4.5
Values 11 2.4 1.7 0.91 1.2
[16]
HepG2 PLCG1
Mean 87.8
Standard deviation 4.3
Values 91 85
[17]
HepG2.C3A PLCG1
Mean 60.1
Standard deviation 10
Values 67 53
[18]
HuH.7 PLCG1
Mean 36.2
Standard deviation 5.9
Values 40 30 39
[19]
SNU475 PLCG1
Mean 45.9
Standard deviation 1.9
Values 47 45
[20]
THLE PLCG1
Mean 36.2
Standard deviation 0.92
Values 36 37
[21]
liver PLCG1
Mean 6.36
Standard deviation 4.9
Values 2.3 8.9 2.2 12
[22]
ref_hepatocyte IRS2
Mean 2.12
Standard deviation 2.3
Values 0.019 0.61 1.4 5.7 2.9
[23]
HepG2 IRS2
Mean 0.0931
Standard deviation 0.071
Values 0.14 0.043
[24]
HepG2.C3A IRS2
Mean 0
Standard deviation 0
Values 0 0
[25]
HuH.7 IRS2
Mean 0.575
Standard deviation 0.68
Values 0.2 1.4 0.17
[26]
SNU475 IRS2
Mean 2.45
Standard deviation 0.45
Values 2.1 2.8
[27]
THLE IRS2
Mean 39
Standard deviation 5.9
Values 35 43
[28]
liver IRS2
Mean 15.7
Standard deviation 9.9
Values 29 11 6.3 17
[29]
ref_hepatocyte PLCG2
Mean 0.967
Standard deviation 0.77
Values 0 0.93 0.46 1.9 1.6
[30]
HepG2 PLCG2
Mean 0.879
Standard deviation 0.82
Values 1.5 0.3
[31]
HepG2.C3A PLCG2
Mean 0.0146
Standard deviation 0.021
Values 0.029 0
[32]
HuH.7 PLCG2
Mean 2.44
Standard deviation 1.1
Values 1.9 3.7 1.8
[33]
SNU475 PLCG2
Mean 0.267
Standard deviation 0.089
Values 0.2 0.33
[34]
THLE PLCG2
Mean 0.664
Standard deviation 0.061
Values 0.62 0.71
[35]
liver PLCG2
Mean 9.03
Standard deviation 2.5
Values 12 10 5.7 8.7
[36]
ref_hepatocyte JAK2
Mean 0.762
Standard deviation 0.48
Values 1.3 1.3 0.62 0.18 0.5
[37]
HepG2 JAK2
Mean 1.97
Standard deviation 1.3
Values 1 2.9
[38]
HepG2.C3A JAK2
Mean 1.75
Standard deviation 0.67
Values 1.3 2.2
[39]
HuH.7 JAK2
Mean 1.23
Standard deviation 0.34
Values 1.2 1.6 0.9
[40]
SNU475 JAK2
Mean 2.37
Standard deviation 0.1
Values 2.3 2.4
[41]
THLE JAK2
Mean 4.02
Standard deviation 0.77
Values 4.6 3.5
[42]
liver JAK2
Mean 7.06
Standard deviation 3.8
Values 4.7 11 2.9 9.8
[43]
ref_hepatocyte EPOR
Mean 0.552
Standard deviation 0.22
Values 0.24 0.48 0.53 0.69 0.82
[44]
HepG2 EPOR
Mean 2.93
Standard deviation 0.93
Values 3.6 2.3
[45]
HepG2.C3A EPOR
Mean 5.68
Standard deviation 2.7
Values 7.6 3.8
[46]
HuH.7 EPOR
Mean 11.1
Standard deviation 0.46
Values 11 11 11
[47]
SNU475 EPOR
Mean 2.28
Standard deviation 0.26
Values 2.1 2.5
[48]
THLE EPOR
Mean 4.55
Standard deviation 0.058
Values 4.5 4.6
[49]
liver EPOR
Mean 4.7
Standard deviation 1.7
Values 6.5 3.4 5.7 3.1