REACTOME_ERBB2_REGULATES_CELL_MOTILITY Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 RHOA Transforming protein RhoA [1] -0.76[2] -1.26[3] -1.10[4] -0.47[5] -0.27[6] -1.14[7]
2 DIAPH1 Protein diaphanous homolog 1 [8] 0.79[9] 0.45[10] 0.81[11] 0.67[12] 0.84[13] 1.11[14]
3 MEMO1 Protein MEMO1 [15] -0.55[16] -0.09[17] -0.84[18] 0.14[19] -1.01[20] -0.92[21]
4 ERBB3 Receptor tyrosine-protein kinase erbB-3 [22] 2.19[23] 3.57[24] 2.54[25] -5.12[26] -5.12[27] 2.49[28]
5 ERBB2 Receptor tyrosine-protein kinase erbB-2 [29] 2.55[30] 1.37[31] 2.48[32] 2.01[33] 1.36[34] 0.34[35]
6 EGFR Epidermal growth factor receptor [36] -0.52[37] -0.89[38] 1.92[39] 1.19[40] 1.55[41] 2.84[42]
7 HBEGF Proheparin-binding EGF-like growth factor [43] -0.81[44] -1.62[45] -2.75[46] 1.06[47] 0.49[48] -2.24[49]
8 NRG1 Pro-neuregulin-1, membrane-bound isoform [50] 0.52[51] -5.62[52] -2.80[53] 2.80[54] -4.92[55] 0.96[56]
9 BTC Probetacellulin [57] -7.96[58] -8.35[59] -4.20[60] -2.12[61] -2.40[62] -2.73[63]
10 NRG4 Pro-neuregulin-4, membrane-bound isoform [64] -3.91[65] -1.03[66] -1.15[67] 1.04[68] -1.41[69] -0.75[70]
11 EREG Proepiregulin [71] 1.93[72] 1.86[73] -2.62[74] -0.81[75] 4.19[76] -1.29[77]
12 EGF Pro-epidermal growth factor [78] 2.15[79] 3.94[80] 7.48[81] 9.78[82] 6.95[83] 1.76[84]
13 ERBB4 Receptor tyrosine-protein kinase erbB-4 [85] [86] [87] [88] [89] [90] [91]
14 NRG3 Pro-neuregulin-3, membrane-bound isoform [92] [93] [94] [95] [96] [97] [98]
15 NRG2 Pro-neuregulin-2, membrane-bound isoform [99] [100] [101] [102] [103] [104] [105]
[1]
ref_hepatocyte RHOA
Mean 177
Standard deviation 1.2e+02
Values 2.2e+02 3.8e+02 1.4e+02 75 79
[2]
HepG2 RHOA
Mean 204
Standard deviation 38
Values 2.3e+02 1.8e+02
[3]
HepG2.C3A RHOA
Mean 129
Standard deviation 1.6
Values 1.3e+02 1.3e+02
[4]
HuH.7 RHOA
Mean 144
Standard deviation 23
Values 1.6e+02 1.2e+02 1.6e+02
[5]
SNU475 RHOA
Mean 139
Standard deviation 21
Values 1.5e+02 1.2e+02
[6]
THLE RHOA
Mean 214
Standard deviation 38
Values 1.9e+02 2.4e+02
[7]
liver RHOA
Mean 101
Standard deviation 59
Values 1.6e+02 54 1.4e+02 46
[8]
ref_hepatocyte DIAPH1
Mean 27.3
Standard deviation 11
Values 30 44 27 20 17
[9]
HepG2 DIAPH1
Mean 92.2
Standard deviation 5.3
Values 88 96
[10]
HepG2.C3A DIAPH1
Mean 64.8
Standard deviation 5.9
Values 61 69
[11]
HuH.7 DIAPH1
Mean 83.7
Standard deviation 19
Values 1.1e+02 70 75
[12]
SNU475 DIAPH1
Mean 47.5
Standard deviation 4.1
Values 45 50
[13]
THLE DIAPH1
Mean 71.3
Standard deviation 15
Values 61 82
[14]
liver DIAPH1
Mean 73.8
Standard deviation 23
Values 1e+02 56 79 56
[15]
ref_hepatocyte MEMO1
Mean 16.8
Standard deviation 8.7
Values 16 31 8.2 14 14
[16]
HepG2 MEMO1
Mean 22.3
Standard deviation 0.51
Values 22 23
[17]
HepG2.C3A MEMO1
Mean 27.4
Standard deviation 0.43
Values 27 28
[18]
HuH.7 MEMO1
Mean 16.3
Standard deviation 2.7
Values 14 19 16
[19]
SNU475 MEMO1
Mean 20.1
Standard deviation 2.9
Values 22 18
[20]
THLE MEMO1
Mean 12
Standard deviation 2
Values 11 13
[21]
liver MEMO1
Mean 11.1
Standard deviation 5.2
Values 19 7.4 11 7.7
[22]
ref_hepatocyte ERBB3
Mean 8.22
Standard deviation 4
Values 12 3.8 4.1 11 10
[23]
HepG2 ERBB3
Mean 72.9
Standard deviation 2.6
Values 75 71
[24]
HepG2.C3A ERBB3
Mean 169
Standard deviation 42
Values 2e+02 1.4e+02
[25]
HuH.7 ERBB3
Mean 83.4
Standard deviation 7.8
Values 92 80 78
[26]
SNU475 ERBB3
Mean 0.258
Standard deviation 0.12
Values 0.18 0.34
[27]
THLE ERBB3
Mean 0.344
Standard deviation 0.05
Values 0.38 0.31
[28]
liver ERBB3
Mean 57.8
Standard deviation 20
Values 44 71 39 79
[29]
ref_hepatocyte ERBB2
Mean 6.44
Standard deviation 3.8
Values 13 3.9 4.7 3.7 7.1
[30]
HepG2 ERBB2
Mean 73.6
Standard deviation 10
Values 66 81
[31]
HepG2.C3A ERBB2
Mean 29
Standard deviation 6.9
Values 34 24
[32]
HuH.7 ERBB2
Mean 62.5
Standard deviation 7.1
Values 69 55 63
[33]
SNU475 ERBB2
Mean 28.2
Standard deviation 8.4
Values 34 22
[34]
THLE ERBB2
Mean 24.1
Standard deviation 2.7
Values 22 26
[35]
liver ERBB2
Mean 10.2
Standard deviation 3.4
Values 7.9 8.1 9.6 15
[36]
ref_hepatocyte EGFR
Mean 5.53
Standard deviation 4.2
Values 0.94 8.5 11 3.5 3.5
[37]
HepG2 EGFR
Mean 7.53
Standard deviation 0.89
Values 6.9 8.2
[38]
HepG2.C3A EGFR
Mean 5.18
Standard deviation 0.67
Values 5.7 4.7
[39]
HuH.7 EGFR
Mean 36.6
Standard deviation 25
Values 32 63 15
[40]
SNU475 EGFR
Mean 13.7
Standard deviation 0.74
Values 13 14
[41]
THLE EGFR
Mean 23.6
Standard deviation 4.4
Values 20 27
[42]
liver EGFR
Mean 49.4
Standard deviation 14
Values 39 69 47 42
[43]
ref_hepatocyte HBEGF
Mean 1.81
Standard deviation 1.5
Values 1 3.1 3.8 0.78 0.34
[44]
HepG2 HBEGF
Mean 2.02
Standard deviation 0.16
Values 2.1 1.9
[45]
HepG2.C3A HBEGF
Mean 1.02
Standard deviation 0.3
Values 1.2 0.82
[46]
HuH.7 HBEGF
Mean 0.469
Standard deviation 0.044
Values 0.52 0.43 0.46
[47]
SNU475 HBEGF
Mean 4.11
Standard deviation 0.34
Values 3.9 4.4
[48]
THLE HBEGF
Mean 3.71
Standard deviation 0.17
Values 3.8 3.6
[49]
liver HBEGF
Mean 0.478
Standard deviation 0.29
Values 0.89 0.27 0.28 0.46
[50]
ref_hepatocyte NRG1
Mean 1.2
Standard deviation 1
Values 0 1 2.8 1.5 0.74
[51]
HepG2 NRG1
Mean 3.35
Standard deviation 2.7
Values 1.4 5.3
[52]
HepG2.C3A NRG1
Mean 0.0424
Standard deviation 0.046
Values 0.0097 0.075
[53]
HuH.7 NRG1
Mean 0.302
Standard deviation 0.17
Values 0.16 0.49 0.25
[54]
SNU475 NRG1
Mean 9.16
Standard deviation 3.3
Values 12 6.8
[55]
THLE NRG1
Mean 0.0576
Standard deviation 0.031
Values 0.035 0.08
[56]
liver NRG1
Mean 2.92
Standard deviation 2.1
Values 1.2 5.5 3.6 1.2
[57]
ref_hepatocyte BTC
Mean 0.915
Standard deviation 1.9
Values 0 4.4 0.079 0 0.12
[58]
HepG2 BTC
Mean 0.00716
Standard deviation 0.002
Values 0.0057 0.0086
[59]
HepG2.C3A BTC
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[60]
HuH.7 BTC
Mean 0.087
Standard deviation 0.09
Values 0.066 0.19 0.0094
[61]
SNU475 BTC
Mean 0.229
Standard deviation 0.03
Values 0.25 0.21
[62]
THLE BTC
Mean 0.251
Standard deviation 0.13
Values 0.34 0.16
[63]
liver BTC
Mean 0.172
Standard deviation 0.058
Values 0.21 0.23 0.1 0.15
[64]
ref_hepatocyte NRG4
Mean 0.631
Standard deviation 0.35
Values 0 0.75 0.81 0.78 0.81
[65]
HepG2 NRG4
Mean 0.0816
Standard deviation 0.03
Values 0.1 0.06
[66]
HepG2.C3A NRG4
Mean 0.534
Standard deviation 0.042
Values 0.56 0.5
[67]
HuH.7 NRG4
Mean 0.494
Standard deviation 0.053
Values 0.43 0.51 0.53
[68]
SNU475 NRG4
Mean 1.41
Standard deviation 0.46
Values 1.7 1.1
[69]
THLE NRG4
Mean 0.345
Standard deviation 0.16
Values 0.46 0.23
[70]
liver NRG4
Mean 0.468
Standard deviation 0.12
Values 0.45 0.41 0.64 0.37
[71]
ref_hepatocyte EREG
Mean 0.24
Standard deviation 0.13
Values 0.3 0.18 0.15 0.13 0.45
[72]
HepG2 EREG
Mean 1.79
Standard deviation 1.2
Values 2.6 0.95
[73]
HepG2.C3A EREG
Mean 1.51
Standard deviation 1
Values 0.81 2.2
[74]
HuH.7 EREG
Mean 0.068
Standard deviation 0.032
Values 0.033 0.096 0.075
[75]
SNU475 EREG
Mean 0.149
Standard deviation 0.12
Values 0.065 0.23
[76]
THLE EREG
Mean 6.34
Standard deviation 2.2
Values 7.9 4.8
[77]
liver EREG
Mean 0.123
Standard deviation 0.11
Values 0 0.13 0.26 0.11
[78]
ref_hepatocyte EGF
Mean 0.00415
Standard deviation 0.0093
Values 0 0.021 0 0 0
[79]
HepG2 EGF
Mean 0.0358
Standard deviation 0.014
Values 0.046 0.026
[80]
HepG2.C3A EGF
Mean 0.11
Standard deviation 0.087
Values 0.049 0.17
[81]
HuH.7 EGF
Mean 1.29
Standard deviation 0.44
Values 0.97 1.8 1.1
[82]
SNU475 EGF
Mean 3.97
Standard deviation 0.5
Values 4.3 3.6
[83]
THLE EGF
Mean 0.743
Standard deviation 0.02
Values 0.76 0.73
[84]
liver EGF
Mean 0.0176
Standard deviation 0.027
Values 0 0.057 0 0.013
[85]
ref_hepatocyte ERBB4
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[86]
HepG2 ERBB4
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[87]
HepG2.C3A ERBB4
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[88]
HuH.7 ERBB4
Mean 0.136
Standard deviation 0.15
Values 0.098 0.3 0.0094
[89]
SNU475 ERBB4
Mean 0.0217
Standard deviation 0.0021
Values 0.023 0.02
[90]
THLE ERBB4
Mean 0.0662
Standard deviation 0.027
Values 0.047 0.085
[91]
liver ERBB4
Mean 0.308
Standard deviation 0.33
Values 0.14 0.29 0.026 0.78
[92]
ref_hepatocyte NRG3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[93]
HepG2 NRG3
Mean 0
Standard deviation 0
Values 0 0
[94]
HepG2.C3A NRG3
Mean 0
Standard deviation 0
Values 0 0
[95]
HuH.7 NRG3
Mean 0.376
Standard deviation 0.32
Values 0.18 0.75 0.2
[96]
SNU475 NRG3
Mean 0
Standard deviation 0
Values 0 0
[97]
THLE NRG3
Mean 0
Standard deviation 0
Values 0 0
[98]
liver NRG3
Mean 0.222
Standard deviation 0.073
Values 0.28 0.2 0.13 0.28
[99]
ref_hepatocyte NRG2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[100]
HepG2 NRG2
Mean 0.0236
Standard deviation 0.015
Values 0.034 0.013
[101]
HepG2.C3A NRG2
Mean 0
Standard deviation 0
Values 0 0
[102]
HuH.7 NRG2
Mean 0
Standard deviation 0
Values 0 0 0
[103]
SNU475 NRG2
Mean 0.181
Standard deviation 0.12
Values 0.093 0.27
[104]
THLE NRG2
Mean 0.79
Standard deviation 0.23
Values 0.63 0.95
[105]
liver NRG2
Mean 0.0321
Standard deviation 0.024
Values 0.047 0.029 0 0.053