REACTOME_EPHRIN_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 MYL12A Myosin regulatory light chain 12A [1] -1.38[2] -1.11[3] -1.04[4] -1.26[5] -1.85[6] -1.17[7]
2 RAC1 Ras-related C3 botulinum toxin substrate 1 [8] 0.01[9] -0.08[10] 0.50[11] 0.23[12] 0.25[13] -0.31[14]
3 SDCBP Syntenin-1 [15] -0.61[16] -0.68[17] -1.46[18] 1.25[19] 0.91[20] 0.64[21]
4 PAK2 Serine/threonine-protein kinase PAK 2 [22] 1.85[23] 1.84[24] 2.00[25] 0.97[26] 1.55[27] 2.02[28]
5 EPHB4 Ephrin type-B receptor 4 [29] 2.32[30] 1.94[31] 2.07[32] -0.35[33] 0.47[34] 2.34[35]
6 NCK2 Cytoplasmic protein NCK2 [36] 1.20[37] 1.03[38] -0.69[39] -0.11[40] 0.67[41] -0.17[42]
7 SRC Proto-oncogene tyrosine-protein kinase Src [43] 3.42[44] 3.65[45] 2.52[46] 2.62[47] 1.83[48] -0.20[49]
8 GIT1 ARF GTPase-activating protein GIT1 [50] 2.37[51] 2.49[52] 1.77[53] 2.18[54] 1.92[55] 0.18[56]
9 ARHGEF7 Rho guanine nucleotide exchange factor 7 [57] 2.02[58] 2.26[59] 1.98[60] 2.03[61] 1.82[62] 3.00[63]
10 PAK1 Serine/threonine-protein kinase PAK 1 [64] 0.39[65] -0.12[66] 2.15[67] -1.64[68] 2.18[69] 0.92[70]
11 FYN Tyrosine-protein kinase Fyn [71] 1.34[72] -7.01[73] 1.42[74] 1.69[75] 3.25[76] 1.62[77]
12 EFNB1 Ephrin-B1 [78] 1.74[79] -0.02[80] -7.24[81] 1.83[82] 1.94[83] 1.57[84]
13 EPHB2 Ephrin type-B receptor 2 [85] -0.43[86] -5.25[87] 1.04[88] 2.59[89] 3.37[90] -0.92[91]
14 EPHB6 Ephrin type-B receptor 6 [92] -4.70[93] [94] -7.53[95] -2.47[96] 0.55[97] 1.45[98]
15 EPHB1 Ephrin type-B receptor 1 [99] 1.18[100] -4.26[101] -5.26[102] [103] -5.36[104] 2.42[105]
16 EFNB2 Ephrin-B2 [106] -0.18[107] -2.11[108] 0.69[109] -0.69[110] 5.35[111] 4.48[112]
17 PAK3 Serine/threonine-protein kinase PAK 3 [113] -6.01[114] [115] [116] -1.38[117] 0.37[118] 1.44[119]
18 EPHB3 Ephrin type-B receptor 3 [120] 1.00[121] -3.28[122] 3.87[123] 3.59[124] 3.49[125] 3.66[126]
19 EFNB3 Ephrin-B3 [127] 3.43[128] 0.14[129] 1.62[130] 3.95[131] 6.28[132] 4.32[133]
[1]
ref_hepatocyte MYL12A
Mean 191
Standard deviation 1.4e+02
Values 1.3e+02 4.4e+02 1.5e+02 1.3e+02 97
[2]
HepG2 MYL12A
Mean 122
Standard deviation 3.2
Values 1.2e+02 1.2e+02
[3]
HepG2.C3A MYL12A
Mean 111
Standard deviation 0.56
Values 1.1e+02 1.1e+02
[4]
HuH.7 MYL12A
Mean 123
Standard deviation 22
Values 1.2e+02 1e+02 1.5e+02
[5]
SNU475 MYL12A
Mean 125
Standard deviation 67
Values 1.7e+02 78
[6]
THLE MYL12A
Mean 91.5
Standard deviation 12
Values 83 1e+02
[7]
liver MYL12A
Mean 76.5
Standard deviation 47
Values 1.2e+02 43 1.2e+02 29
[8]
ref_hepatocyte RAC1
Mean 52
Standard deviation 20
Values 28 59 81 45 47
[9]
HepG2 RAC1
Mean 87.4
Standard deviation 1.9
Values 89 86
[10]
HepG2.C3A RAC1
Mean 62
Standard deviation 7.4
Values 67 57
[11]
HuH.7 RAC1
Mean 97.2
Standard deviation 9.7
Values 1e+02 86 1e+02
[12]
SNU475 RAC1
Mean 96.5
Standard deviation 10
Values 89 1e+02
[13]
THLE RAC1
Mean 107
Standard deviation 19
Values 94 1.2e+02
[14]
liver RAC1
Mean 37.8
Standard deviation 32
Values 63 12 67 9.5
[15]
ref_hepatocyte SDCBP
Mean 31.5
Standard deviation 17
Values 29 61 18 19 31
[16]
HepG2 SDCBP
Mean 34.4
Standard deviation 8.7
Values 28 41
[17]
HepG2.C3A SDCBP
Mean 24.7
Standard deviation 4.7
Values 21 28
[18]
HuH.7 SDCBP
Mean 15.2
Standard deviation 3.5
Values 12 19 14
[19]
SNU475 SDCBP
Mean 118
Standard deviation 3.7
Values 1.2e+02 1.2e+02
[20]
THLE SDCBP
Mean 102
Standard deviation 7.2
Values 97 1.1e+02
[21]
liver SDCBP
Mean 44.3
Standard deviation 22
Values 58 30 68 21
[22]
ref_hepatocyte PAK2
Mean 10.9
Standard deviation 2.8
Values 11 15 11 7.6 9.9
[23]
HepG2 PAK2
Mean 65.6
Standard deviation 14
Values 56 75
[24]
HepG2.C3A PAK2
Mean 49.1
Standard deviation 0.79
Values 49 50
[25]
HuH.7 PAK2
Mean 57.7
Standard deviation 11
Values 66 61 46
[26]
SNU475 PAK2
Mean 33.8
Standard deviation 4.3
Values 37 31
[27]
THLE PAK2
Mean 55.3
Standard deviation 9.9
Values 48 62
[28]
liver PAK2
Mean 39.9
Standard deviation 5.7
Values 44 41 43 32
[29]
ref_hepatocyte EPHB4
Mean 7.09
Standard deviation 3.9
Values 5.6 3.6 5.7 14 6.8
[30]
HepG2 EPHB4
Mean 59.2
Standard deviation 7.9
Values 65 54
[31]
HepG2.C3A EPHB4
Mean 34.1
Standard deviation 9.2
Values 41 28
[32]
HuH.7 EPHB4
Mean 39.4
Standard deviation 8.9
Values 48 30 40
[33]
SNU475 EPHB4
Mean 8.79
Standard deviation 1.7
Values 7.6 10
[34]
THLE EPHB4
Mean 17
Standard deviation 0.56
Values 17 17
[35]
liver EPHB4
Mean 32.4
Standard deviation 11
Values 24 46 22 37
[36]
ref_hepatocyte NCK2
Mean 4.8
Standard deviation 3.5
Values 9.1 5.5 7 1.3 1
[37]
HepG2 NCK2
Mean 18.4
Standard deviation 3.6
Values 21 16
[38]
HepG2.C3A NCK2
Mean 12.3
Standard deviation 3.8
Values 15 9.6
[39]
HuH.7 NCK2
Mean 3.94
Standard deviation 0.32
Values 3.8 4.3 3.7
[40]
SNU475 NCK2
Mean 7.02
Standard deviation 0.0081
Values 7 7
[41]
THLE NCK2
Mean 13.2
Standard deviation 0.15
Values 13 13
[42]
liver NCK2
Mean 3.85
Standard deviation 2.3
Values 3.3 3.9 1.3 6.9
[43]
ref_hepatocyte SRC
Mean 3.67
Standard deviation 3.6
Values 9.6 4.7 2.2 0.77 1.2
[44]
HepG2 SRC
Mean 66
Standard deviation 21
Values 81 51
[45]
HepG2.C3A SRC
Mean 58.1
Standard deviation 18
Values 71 45
[46]
HuH.7 SRC
Mean 27.9
Standard deviation 2
Values 28 29 26
[47]
SNU475 SRC
Mean 35.6
Standard deviation 3.5
Values 38 33
[48]
THLE SRC
Mean 22.5
Standard deviation 2.7
Values 21 24
[49]
liver SRC
Mean 2.9
Standard deviation 1
Values 4.1 2.5 1.7 3.2
[50]
ref_hepatocyte GIT1
Mean 3.28
Standard deviation 2.2
Values 5.7 2.2 5.7 1.6 1.2
[51]
HepG2 GIT1
Mean 28.4
Standard deviation 7.9
Values 34 23
[52]
HepG2.C3A GIT1
Mean 23.2
Standard deviation 4.7
Values 26 20
[53]
HuH.7 GIT1
Mean 14.8
Standard deviation 0.47
Values 15 15 14
[54]
SNU475 GIT1
Mean 23.4
Standard deviation 0.14
Values 24 23
[55]
THLE GIT1
Mean 21.4
Standard deviation 1.3
Values 21 22
[56]
liver GIT1
Mean 3.36
Standard deviation 0.78
Values 3.4 3.5 2.3 4.2
[57]
ref_hepatocyte ARHGEF7
Mean 2.72
Standard deviation 0.57
Values 2 2.5 3.3 3.2 2.6
[58]
HepG2 ARHGEF7
Mean 18.5
Standard deviation 3.4
Values 16 21
[59]
HepG2.C3A ARHGEF7
Mean 16.4
Standard deviation 1.2
Values 17 16
[60]
HuH.7 ARHGEF7
Mean 14.2
Standard deviation 1.4
Values 14 13 15
[61]
SNU475 ARHGEF7
Mean 17.6
Standard deviation 3.5
Values 20 15
[62]
THLE ARHGEF7
Mean 16.6
Standard deviation 2.5
Values 15 18
[63]
liver ARHGEF7
Mean 19.7
Standard deviation 3.9
Values 24 19 15 21
[64]
ref_hepatocyte PAK1
Mean 2.3
Standard deviation 0.59
Values 1.7 3 2.9 2.1 1.9
[65]
HepG2 PAK1
Mean 5.05
Standard deviation 1.5
Values 6.1 4
[66]
HepG2.C3A PAK1
Mean 2.65
Standard deviation 0.51
Values 3 2.3
[67]
HuH.7 PAK1
Mean 13.5
Standard deviation 2.2
Values 12 16 12
[68]
SNU475 PAK1
Mean 1.17
Standard deviation 0.24
Values 1 1.3
[69]
THLE PAK1
Mean 18
Standard deviation 0.72
Values 18 17
[70]
liver PAK1
Mean 3.94
Standard deviation 1.1
Values 5.3 4 3.9 2.6
[71]
ref_hepatocyte FYN
Mean 2.1
Standard deviation 2.2
Values 2.2 0.039 0.23 2.6 5.5
[72]
HepG2 FYN
Mean 8.91
Standard deviation 0.7
Values 9.4 8.4
[73]
HepG2.C3A FYN
Mean 0.0204
Standard deviation 0.0014
Values 0.019 0.021
[74]
HuH.7 FYN
Mean 7.43
Standard deviation 2.2
Values 8.9 4.8 8.5
[75]
SNU475 FYN
Mean 10.7
Standard deviation 2.5
Values 12 8.9
[76]
THLE FYN
Mean 34.5
Standard deviation 4.9
Values 38 31
[77]
liver FYN
Mean 5.84
Standard deviation 2.1
Values 8.9 4.4 5.1 5
[78]
ref_hepatocyte EFNB1
Mean 1.73
Standard deviation 0.97
Values 0.32 1.6 3 1.6 2.1
[79]
HepG2 EFNB1
Mean 9.67
Standard deviation 2
Values 11 8.3
[80]
HepG2.C3A EFNB1
Mean 2.14
Standard deviation 0.18
Values 2 2.3
[81]
HuH.7 EFNB1
Mean 0.0152
Standard deviation 0.017
Values 0.033 0.013 0
[82]
SNU475 EFNB1
Mean 9.73
Standard deviation 3.1
Values 12 7.6
[83]
THLE EFNB1
Mean 11.4
Standard deviation 1.7
Values 10 13
[84]
liver EFNB1
Mean 4.63
Standard deviation 1.4
Values 5.6 4.6 2.6 5.7
[85]
ref_hepatocyte EPHB2
Mean 0.766
Standard deviation 0.96
Values 0 1.7 2 0.15 0.065
[86]
HepG2 EPHB2
Mean 0.949
Standard deviation 0.65
Values 1.4 0.49
[87]
HepG2.C3A EPHB2
Mean 0.0253
Standard deviation 0.0055
Values 0.029 0.021
[88]
HuH.7 EPHB2
Mean 2.09
Standard deviation 1.4
Values 3.2 0.54 2.5
[89]
SNU475 EPHB2
Mean 7.27
Standard deviation 2.9
Values 5.2 9.3
[90]
THLE EPHB2
Mean 13.6
Standard deviation 2
Values 12 15
[91]
liver EPHB2
Mean 0.366
Standard deviation 0.19
Values 0.19 0.37 0.28 0.62
[92]
ref_hepatocyte EPHB6
Mean 0.68
Standard deviation 0.59
Values 0 1.4 1 0.84 0.15
[93]
HepG2 EPHB6
Mean 0.0436
Standard deviation 0.029
Values 0.023 0.064
[94]
HepG2.C3A EPHB6
Mean 0
Standard deviation 0
Values 0 0
[95]
HuH.7 EPHB6
Mean 0.00487
Standard deviation 0.0043
Values 0.0082 0.0064 0
[96]
SNU475 EPHB6
Mean 0.194
Standard deviation 0.23
Values 0.032 0.35
[97]
THLE EPHB6
Mean 1.72
Standard deviation 0.045
Values 1.7 1.8
[98]
liver EPHB6
Mean 1.68
Standard deviation 1
Values 3.1 0.66 1.4 1.5
[99]
ref_hepatocyte EPHB1
Mean 0.401
Standard deviation 0.55
Values 0 0.1 0.21 1.4 0.34
[100]
HepG2 EPHB1
Mean 1.53
Standard deviation 1.4
Values 2.5 0.51
[101]
HepG2.C3A EPHB1
Mean 0.0263
Standard deviation 0.023
Values 0.0097 0.043
[102]
HuH.7 EPHB1
Mean 0.0139
Standard deviation 0.0065
Values 0.016 0.0064 0.019
[103]
SNU475 EPHB1
Mean 0
Standard deviation 0
Values 0 0
[104]
THLE EPHB1
Mean 0.0169
Standard deviation 0.0013
Values 0.018 0.016
[105]
liver EPHB1
Mean 1.93
Standard deviation 1.4
Values 0.94 3.1 3.2 0.48
[106]
ref_hepatocyte EFNB2
Mean 0.21
Standard deviation 0.26
Values 0 0.026 0.55 0.41 0.057
[107]
HepG2 EFNB2
Mean 0.31
Standard deviation 0.11
Values 0.23 0.39
[108]
HepG2.C3A EFNB2
Mean 0.0613
Standard deviation 0.0043
Values 0.058 0.064
[109]
HuH.7 EFNB2
Mean 0.448
Standard deviation 0.17
Values 0.64 0.39 0.32
[110]
SNU475 EFNB2
Mean 0.206
Standard deviation 0.16
Values 0.093 0.32
[111]
THLE EFNB2
Mean 14.8
Standard deviation 4.4
Values 12 18
[112]
liver EFNB2
Mean 4.22
Standard deviation 2
Values 6.7 3.4 2 4.8
[113]
ref_hepatocyte PAK3
Mean 0.0826
Standard deviation 0.14
Values 0 0 0.33 0 0.081
[114]
HepG2 PAK3
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[115]
HepG2.C3A PAK3
Mean 0
Standard deviation 0
Values 0 0
[116]
HuH.7 PAK3
Mean 0
Standard deviation 0
Values 0 0 0
[117]
SNU475 PAK3
Mean 0.05
Standard deviation 0.051
Values 0.014 0.086
[118]
THLE PAK3
Mean 0.185
Standard deviation 0.065
Values 0.23 0.14
[119]
liver PAK3
Mean 0.202
Standard deviation 0.041
Values 0.24 0.14 0.21 0.23
[120]
ref_hepatocyte EPHB3
Mean 0.0375
Standard deviation 0.057
Values 0 0.14 0 0.026 0.024
[121]
HepG2 EPHB3
Mean 0.126
Standard deviation 0.089
Values 0.063 0.19
[122]
HepG2.C3A EPHB3
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[123]
HuH.7 EPHB3
Mean 0.727
Standard deviation 0.098
Values 0.75 0.81 0.62
[124]
SNU475 EPHB3
Mean 0.712
Standard deviation 0.3
Values 0.5 0.92
[125]
THLE EPHB3
Mean 0.727
Standard deviation 0.18
Values 0.85 0.6
[126]
liver EPHB3
Mean 0.427
Standard deviation 0.16
Values 0.28 0.46 0.33 0.64
[127]
ref_hepatocyte EFNB3
Mean 0.0179
Standard deviation 0.025
Values 0 0 0.049 0 0.041
[128]
HepG2 EFNB3
Mean 0.324
Standard deviation 0.29
Values 0.53 0.12
[129]
HepG2.C3A EFNB3
Mean 0.0248
Standard deviation 0.02
Values 0.039 0.011
[130]
HuH.7 EFNB3
Mean 0.0727
Standard deviation 0.04
Values 0.11 0.083 0.028
[131]
SNU475 EFNB3
Mean 0.435
Standard deviation 0.051
Values 0.4 0.47
[132]
THLE EFNB3
Mean 2.4
Standard deviation 0.14
Values 2.3 2.5
[133]
liver EFNB3
Mean 0.322
Standard deviation 0.1
Values 0.31 0.2 0.33 0.45