REACTOME_EGFR_TRANSACTIVATION_BY_GASTRIN Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 GRB2 Growth factor receptor-bound protein 2 [1] 0.76[2] 0.45[3] 0.16[4] 0.04[5] 0.14[6] -0.11[7]
2 NRAS GTPase NRas [8] 0.19[9] 0.48[10] 0.48[11] 0.48[12] 0.24[13] -0.66[14]
3 HRAS GTPase HRas [15] -1.44[16] -2.29[17] -3.50[18] -1.46[19] -1.49[20] -3.07[21]
4 MMP3 Stromelysin-1 [22] -4.95[23] -10.01[24] -12.80[25] -2.26[26] -5.13[27] -8.73[28]
5 KRAS GTPase KRas [29] -0.95[30] -1.11[31] 0.07[32] 0.29[33] 0.13[34] 0.27[35]
6 SOS1 Son of sevenless homolog 1 [36] -0.54[37] 0.85[38] -0.06[39] 0.33[40] -0.25[41] 0.13[42]
7 EGFR Epidermal growth factor receptor [43] -1.13[44] -1.65[45] 0.81[46] -0.08[47] 0.72[48] 2.25[49]
8 PRKCA Protein kinase C alpha type [50] 2.40[51] 2.30[52] 2.24[53] 1.64[54] 2.18[55] 1.51[56]
9 HBEGF Proheparin-binding EGF-like growth factor [57] -1.42[58] -2.38[59] -3.86[60] -0.21[61] -0.34[62] -2.84[63]
[1]
ref_hepatocyte GRB2
Mean 20.7
Standard deviation 5.5
Values 27 26 20 14 17
[2]
HepG2 GRB2
Mean 104
Standard deviation 4.7
Values 1e+02 1.1e+02
[3]
HepG2.C3A GRB2
Mean 83.1
Standard deviation 0.44
Values 83 83
[4]
HuH.7 GRB2
Mean 86.7
Standard deviation 7.6
Values 89 78 93
[5]
SNU475 GRB2
Mean 55.7
Standard deviation 1.4
Values 55 57
[6]
THLE GRB2
Mean 58.8
Standard deviation 3.7
Values 56 61
[7]
liver GRB2
Mean 36.1
Standard deviation 16
Values 50 22 50 22
[8]
ref_hepatocyte NRAS
Mean 14.4
Standard deviation 13
Values 32 23 9.3 3.3 4.6
[9]
HepG2 NRAS
Mean 49.3
Standard deviation 10
Values 42 57
[10]
HepG2.C3A NRAS
Mean 59.2
Standard deviation 18
Values 47 72
[11]
HuH.7 NRAS
Mean 75.6
Standard deviation 9.1
Values 86 70 71
[12]
SNU475 NRAS
Mean 52.9
Standard deviation 9.2
Values 59 46
[13]
THLE NRAS
Mean 44
Standard deviation 8.9
Values 38 50
[14]
liver NRAS
Mean 17.2
Standard deviation 2.6
Values 14 21 18 16
[15]
ref_hepatocyte HRAS
Mean 11.6
Standard deviation 9
Values 4 27 11 7.4 8.8
[16]
HepG2 HRAS
Mean 12.7
Standard deviation 1.1
Values 14 12
[17]
HepG2.C3A HRAS
Mean 6.96
Standard deviation 1.3
Values 6 7.9
[18]
HuH.7 HRAS
Mean 3.85
Standard deviation 1.6
Values 3.6 2.4 5.6
[19]
SNU475 HRAS
Mean 11
Standard deviation 0.62
Values 11 11
[20]
THLE HRAS
Mean 10.7
Standard deviation 2.3
Values 9.1 12
[21]
liver HRAS
Mean 2.6
Standard deviation 1.6
Values 4.1 1.1 3.8 1.4
[22]
ref_hepatocyte MMP3
Mean 9.23
Standard deviation 20
Values 0 0.19 45 1.1 0
[23]
HepG2 MMP3
Mean 0.894
Standard deviation 0.62
Values 1.3 0.46
[24]
HepG2.C3A MMP3
Mean 0.0263
Standard deviation 0.023
Values 0.0097 0.043
[25]
HuH.7 MMP3
Mean 0.00487
Standard deviation 0.0043
Values 0.0082 0.0064 0
[26]
SNU475 MMP3
Mean 5.06
Standard deviation 4.7
Values 1.8 8.4
[27]
THLE MMP3
Mean 0.682
Standard deviation 0.55
Values 0.29 1.1
[28]
liver MMP3
Mean 0.0408
Standard deviation 0.05
Values 0.024 0.11 0.026 0
[29]
ref_hepatocyte KRAS
Mean 8.97
Standard deviation 7.9
Values 18 17 5.4 1.7 2.7
[30]
HepG2 KRAS
Mean 13.9
Standard deviation 3.1
Values 12 16
[31]
HepG2.C3A KRAS
Mean 12.2
Standard deviation 2.3
Values 11 14
[32]
HuH.7 KRAS
Mean 35.4
Standard deviation 4.8
Values 40 30 36
[33]
SNU475 KRAS
Mean 28.7
Standard deviation 5.5
Values 33 25
[34]
THLE KRAS
Mean 25.4
Standard deviation 1.5
Values 24 26
[35]
liver KRAS
Mean 20.4
Standard deviation 8.7
Values 33 16 19 14
[36]
ref_hepatocyte SOS1
Mean 6.81
Standard deviation 11
Values 27 1.9 2.2 1.3 1.5
[37]
HepG2 SOS1
Mean 14
Standard deviation 6.5
Values 9.4 19
[38]
HepG2.C3A SOS1
Mean 36.1
Standard deviation 3.7
Values 39 33
[39]
HuH.7 SOS1
Mean 24.6
Standard deviation 11
Values 22 37 15
[40]
SNU475 SOS1
Mean 22.5
Standard deviation 3.3
Values 25 20
[41]
THLE SOS1
Mean 14.8
Standard deviation 1.4
Values 16 14
[42]
liver SOS1
Mean 14.1
Standard deviation 3.8
Values 13 18 9.3 16
[43]
ref_hepatocyte EGFR
Mean 5.53
Standard deviation 4.2
Values 0.94 8.5 11 3.5 3.5
[44]
HepG2 EGFR
Mean 7.53
Standard deviation 0.89
Values 6.9 8.2
[45]
HepG2.C3A EGFR
Mean 5.18
Standard deviation 0.67
Values 5.7 4.7
[46]
HuH.7 EGFR
Mean 36.6
Standard deviation 25
Values 32 63 15
[47]
SNU475 EGFR
Mean 13.7
Standard deviation 0.74
Values 13 14
[48]
THLE EGFR
Mean 23.6
Standard deviation 4.4
Values 20 27
[49]
liver EGFR
Mean 49.4
Standard deviation 14
Values 39 69 47 42
[50]
ref_hepatocyte PRKCA
Mean 2.45
Standard deviation 2.1
Values 2.7 6 1.1 1.2 1.2
[51]
HepG2 PRKCA
Mean 38.7
Standard deviation 5.6
Values 35 43
[52]
HepG2.C3A PRKCA
Mean 35.5
Standard deviation 4.5
Values 32 39
[53]
HuH.7 PRKCA
Mean 43.7
Standard deviation 11
Values 54 44 33
[54]
SNU475 PRKCA
Mean 20
Standard deviation 4.3
Values 17 23
[55]
THLE PRKCA
Mean 28.8
Standard deviation 11
Values 21 36
[56]
liver PRKCA
Mean 13.2
Standard deviation 7.1
Values 11 17 4.7 21
[57]
ref_hepatocyte HBEGF
Mean 1.81
Standard deviation 1.5
Values 1 3.1 3.8 0.78 0.34
[58]
HepG2 HBEGF
Mean 2.02
Standard deviation 0.16
Values 2.1 1.9
[59]
HepG2.C3A HBEGF
Mean 1.02
Standard deviation 0.3
Values 1.2 0.82
[60]
HuH.7 HBEGF
Mean 0.469
Standard deviation 0.044
Values 0.52 0.43 0.46
[61]
SNU475 HBEGF
Mean 4.11
Standard deviation 0.34
Values 3.9 4.4
[62]
THLE HBEGF
Mean 3.71
Standard deviation 0.17
Values 3.8 3.6
[63]
liver HBEGF
Mean 0.478
Standard deviation 0.29
Values 0.89 0.27 0.28 0.46