REACTOME_DOWNREGULATION_OF_ERBB4_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 UBB Polyubiquitin-B [1] -0.23[2] -0.47[3] -0.50[4] -0.35[5] -0.10[6] -0.10[7]
2 RPS27A Ubiquitin-40S ribosomal protein S27a [8] [9] [10] [11] [12] [13] [14]
3 UBC Polyubiquitin-C [15] 0.21[16] 0.28[17] -0.13[18] 0.50[19] 0.28[20] 0.36[21]
4 UBA52 Ubiquitin-60S ribosomal protein L40 [22] 2.65[23] 2.51[24] 3.38[25] 1.90[26] 2.51[27] 1.13[28]
5 WWP1 NEDD4-like E3 ubiquitin-protein ligase WWP1 [29] 1.98[30] 2.96[31] 3.17[32] 2.21[33] 1.60[34] 3.94[35]
6 ITCH E3 ubiquitin-protein ligase Itchy homolog [36] 3.32[37] 3.80[38] 2.89[39] 3.96[40] 3.08[41] 3.95[42]
7 SRC Proto-oncogene tyrosine-protein kinase Src [43] 4.99[44] 4.94[45] 3.76[46] 4.83[47] 3.80[48] 0.93[49]
8 NEDD4 E3 ubiquitin-protein ligase NEDD4 [50] 1.51[51] 3.54[52] 3.50[53] 3.43[54] 3.49[55] 3.98[56]
9 ERBB4 Receptor tyrosine-protein kinase erbB-4 [57] [58] [59] [60] [61] [62] [63]
[1]
ref_hepatocyte UBB
Mean 764
Standard deviation 4.8e+02
Values 3.8e+02 3.5e+02 5.3e+02 1.2e+03 1.3e+03
[2]
HepG2 UBB
Mean 368
Standard deviation 39
Values 4e+02 3.4e+02
[3]
HepG2.C3A UBB
Mean 285
Standard deviation 14
Values 2.8e+02 3e+02
[4]
HuH.7 UBB
Mean 304
Standard deviation 40
Values 2.9e+02 2.7e+02 3.5e+02
[5]
SNU475 UBB
Mean 204
Standard deviation 3.3
Values 2.1e+02 2e+02
[6]
THLE UBB
Mean 315
Standard deviation 34
Values 2.9e+02 3.4e+02
[7]
liver UBB
Mean 296
Standard deviation 1.3e+02
Values 4.3e+02 2.1e+02 3.9e+02 1.5e+02
[8]
ref_hepatocyte RPS27A
Mean 499
Standard deviation 2.2e+02
Values 6.6e+02 6.1e+02 1.7e+02 6.8e+02 3.8e+02
[9]
HepG2 RPS27A
Missing
[10]
HepG2.C3A RPS27A
Missing
[11]
HuH.7 RPS27A
Missing
[12]
SNU475 RPS27A
Missing
[13]
THLE RPS27A
Missing
[14]
liver RPS27A
Missing
[15]
ref_hepatocyte UBC
Mean 480
Standard deviation 2.8e+02
Values 1.8e+02 3.5e+02 9.1e+02 5.8e+02 3.8e+02
[16]
HepG2 UBC
Mean 314
Standard deviation 38
Values 3.4e+02 2.9e+02
[17]
HepG2.C3A UBC
Mean 302
Standard deviation 41
Values 3.3e+02 2.7e+02
[18]
HuH.7 UBC
Mean 246
Standard deviation 64
Values 2.4e+02 3.1e+02 1.9e+02
[19]
SNU475 UBC
Mean 232
Standard deviation 63
Values 2.8e+02 1.9e+02
[20]
THLE UBC
Mean 257
Standard deviation 41
Values 2.3e+02 2.9e+02
[21]
liver UBC
Mean 254
Standard deviation 78
Values 2.2e+02 3.1e+02 3.3e+02 1.6e+02
[22]
ref_hepatocyte UBA52
Mean 57.3
Standard deviation 43
Values 14 23 49 1.2e+02 81
[23]
HepG2 UBA52
Mean 203
Standard deviation 20
Values 2.2e+02 1.9e+02
[24]
HepG2.C3A UBA52
Mean 169
Standard deviation 3.3
Values 1.7e+02 1.7e+02
[25]
HuH.7 UBA52
Mean 334
Standard deviation 46
Values 3.4e+02 2.8e+02 3.7e+02
[26]
SNU475 UBA52
Mean 72.9
Standard deviation 11
Values 65 81
[27]
THLE UBA52
Mean 144
Standard deviation 15
Values 1.3e+02 1.5e+02
[28]
liver UBA52
Mean 51.7
Standard deviation 26
Values 79 32 68 28
[29]
ref_hepatocyte WWP1
Mean 10.8
Standard deviation 4.8
Values 11 10 4.9 9.3 18
[30]
HepG2 WWP1
Mean 23.9
Standard deviation 7.2
Values 19 29
[31]
HepG2.C3A WWP1
Mean 43.4
Standard deviation 0.75
Values 43 44
[32]
HuH.7 WWP1
Mean 54.2
Standard deviation 3.7
Values 56 57 50
[33]
SNU475 WWP1
Mean 17
Standard deviation 1.8
Values 18 16
[34]
THLE WWP1
Mean 14.4
Standard deviation 1.2
Values 15 14
[35]
liver WWP1
Mean 68.4
Standard deviation 21
Values 70 71 40 92
[36]
ref_hepatocyte ITCH
Mean 9.27
Standard deviation 3.5
Values 14 11 8.6 5.4 7.1
[37]
HepG2 ITCH
Mean 52.1
Standard deviation 13
Values 43 61
[38]
HepG2.C3A ITCH
Mean 67
Standard deviation 7.2
Values 62 72
[39]
HuH.7 ITCH
Mean 38.5
Standard deviation 9.8
Values 38 49 29
[40]
SNU475 ITCH
Mean 49.1
Standard deviation 6.1
Values 53 45
[41]
THLE ITCH
Mean 34.6
Standard deviation 1.8
Values 33 36
[42]
liver ITCH
Mean 59.2
Standard deviation 25
Values 43 75 34 85
[43]
ref_hepatocyte SRC
Mean 3.67
Standard deviation 3.6
Values 9.6 4.7 2.2 0.77 1.2
[44]
HepG2 SRC
Mean 66
Standard deviation 21
Values 81 51
[45]
HepG2.C3A SRC
Mean 58.1
Standard deviation 18
Values 71 45
[46]
HuH.7 SRC
Mean 27.9
Standard deviation 2
Values 28 29 26
[47]
SNU475 SRC
Mean 35.6
Standard deviation 3.5
Values 38 33
[48]
THLE SRC
Mean 22.5
Standard deviation 2.7
Values 21 24
[49]
liver SRC
Mean 2.9
Standard deviation 1
Values 4.1 2.5 1.7 3.2
[50]
ref_hepatocyte NEDD4
Mean 3.56
Standard deviation 2
Values 5.2 6.2 2.5 1.8 2
[51]
HepG2 NEDD4
Mean 5.71
Standard deviation 2.8
Values 3.8 7.7
[52]
HepG2.C3A NEDD4
Mean 21.4
Standard deviation 2.7
Values 19 23
[53]
HuH.7 NEDD4
Mean 22.7
Standard deviation 9.5
Values 20 33 15
[54]
SNU475 NEDD4
Mean 13.1
Standard deviation 0.04
Values 13 13
[55]
THLE NEDD4
Mean 17.6
Standard deviation 1.7
Values 19 16
[56]
liver NEDD4
Mean 23.2
Standard deviation 9.3
Values 22 37 18 16
[57]
ref_hepatocyte ERBB4
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[58]
HepG2 ERBB4
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[59]
HepG2.C3A ERBB4
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[60]
HuH.7 ERBB4
Mean 0.136
Standard deviation 0.15
Values 0.098 0.3 0.0094
[61]
SNU475 ERBB4
Mean 0.0217
Standard deviation 0.0021
Values 0.023 0.02
[62]
THLE ERBB4
Mean 0.0662
Standard deviation 0.027
Values 0.047 0.085
[63]
liver ERBB4
Mean 0.308
Standard deviation 0.33
Values 0.14 0.29 0.026 0.78