REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 VAMP2 Vesicle-associated membrane protein 2 [1] -1.86[2] -1.76[3] -2.33[4] -2.41[5] -1.50[6] -1.67[7]
2 LIN7A Protein lin-7 homolog A [8] -2.04[9] -2.03[10] -2.19[11] -6.70[12] -5.90[13] -2.28[14]
3 LIN7C Protein lin-7 homolog C [15] -0.89[16] 0.00[17] 0.41[18] -2.11[19] -0.91[20] 1.08[21]
4 PPFIA1 Liprin-alpha-1 [22] 1.09[23] 0.59[24] 0.51[25] 2.24[26] 1.07[27] 0.35[28]
5 UNC13B Protein unc-13 homolog B [29] 1.26[30] 1.11[31] 0.84[32] -1.57[33] 0.13[34] 1.09[35]
6 CASK Peripheral plasma membrane protein CASK [36] 1.29[37] 0.93[38] 1.55[39] 0.97[40] 1.38[41] -0.22[42]
7 APBA1 Amyloid-beta A4 precursor protein-binding family A member 1 [43] -7.93[44] -8.43[45] -0.31[46] -4.04[47] -3.53[48] 0.87[49]
8 LIN7B Protein lin-7 homolog B [50] -1.11[51] -0.78[52] -2.31[53] -2.70[54] -1.99[55] -3.16[56]
9 RAB3A Ras-related protein Rab-3A [57] -0.59[58] -1.91[59] -0.71[60] -2.75[61] -1.45[62] -2.70[63]
10 SLC18A2 Synaptic vesicular amine transporter [64] -1.54[65] 0.54[66] -0.02[67] -2.17[68] -0.34[69] 1.81[70]
11 SYN1 Synapsin-1 [71] -2.75[72] -0.65[73] [74] -5.51[75] -0.46[76] -2.26[77]
12 STX1A Syntaxin-1A [78] 0.43[79] 0.14[80] -2.28[81] 0.65[82] 0.76[83] -2.64[84]
13 STXBP1 Syntaxin-binding protein 1 [85] 1.22[86] 1.37[87] 0.87[88] 2.25[89] 3.21[90] -0.64[91]
14 CPLX1 Complexin-1 [92] -1.43[93] -2.75[94] 1.16[95] -4.84[96] -3.77[97] -1.28[98]
15 PPFIA3 Liprin-alpha-3 [99] 2.21[100] 2.37[101] 1.43[102] -1.05[103] -0.36[104] -1.40[105]
16 SNAP25 Synaptosomal-associated protein 25 [106] -4.01[107] -4.07[108] 0.67[109] 0.51[110] 3.67[111] -0.44[112]
17 SYN3 Synapsin-3 [113] 2.69[114] 4.24[115] -0.18[116] [117] -5.15[118] -1.87[119]
18 SYT1 Synaptotagmin-1 [120] -2.61[121] -3.62[122] 4.09[123] 5.24[124] 2.53[125] 2.74[126]
19 SYN2 Synapsin-2 [127] -0.95[128] -1.29[129] -2.75[130] 1.41[131] 3.18[132] 0.32[133]
20 PPFIA2 Liprin-alpha-2 [134] 3.68[135] 6.34[136] 4.74[137] -1.22[138] 0.31[139] 5.42[140]
21 PPFIA4 Liprin-alpha-4 [141] [142] [143] [144] [145] [146] [147]
22 TSPOAP1 Peripheral-type benzodiazepine receptor-associated protein 1 [148] [149] [150] [151] [152] [153] [154]
23 RIMS1 Regulating synaptic membrane exocytosis protein 1 [155] [156] [157] [158] [159] [160] [161]
[1]
ref_hepatocyte VAMP2
Mean 7.38
Standard deviation 2
Values 9.9 5.1 8 8.2 5.7
[2]
HepG2 VAMP2
Mean 6.41
Standard deviation 1.5
Values 7.4 5.4
[3]
HepG2.C3A VAMP2
Mean 7.34
Standard deviation 3
Values 9.5 5.2
[4]
HuH.7 VAMP2
Mean 8.97
Standard deviation 0.78
Values 8.3 8.8 9.8
[5]
SNU475 VAMP2
Mean 9.81
Standard deviation 1.6
Values 11 8.7
[6]
THLE VAMP2
Mean 9.61
Standard deviation 0.14
Values 9.5 9.7
[7]
liver VAMP2
Mean 9.18
Standard deviation 10
Values 22 1 11 1.9
[8]
ref_hepatocyte LIN7A
Mean 6.49
Standard deviation 1.9
Values 4 6.3 9 7.3 5.8
[9]
HepG2 LIN7A
Mean 4.95
Standard deviation 1.2
Values 4.1 5.8
[10]
HepG2.C3A LIN7A
Mean 5.33
Standard deviation 1.4
Values 4.3 6.3
[11]
HuH.7 LIN7A
Mean 8.72
Standard deviation 3
Values 9.5 11 5.4
[12]
SNU475 LIN7A
Mean 0.44
Standard deviation 0.058
Values 0.4 0.48
[13]
THLE LIN7A
Mean 0.4
Standard deviation 0.097
Values 0.33 0.47
[14]
liver LIN7A
Mean 5.27
Standard deviation 1.6
Values 3.5 7.3 5.1 5.1
[15]
ref_hepatocyte LIN7C
Mean 4.95
Standard deviation 2.8
Values 8 4.1 2.2 2.6 7.8
[16]
HepG2 LIN7C
Mean 8.39
Standard deviation 2.3
Values 6.8 10
[17]
HepG2.C3A LIN7C
Mean 16.7
Standard deviation 0.28
Values 17 16
[18]
HuH.7 LIN7C
Mean 40.4
Standard deviation 3.9
Values 43 36 43
[19]
SNU475 LIN7C
Mean 8.08
Standard deviation 1.4
Values 9.1 7.1
[20]
THLE LIN7C
Mean 9.66
Standard deviation 0.22
Values 9.8 9.5
[21]
liver LIN7C
Mean 41.4
Standard deviation 6
Values 33 43 47 43
[22]
ref_hepatocyte PPFIA1
Mean 4.38
Standard deviation 1.7
Values 4 5.6 6.7 2.7 2.9
[23]
HepG2 PPFIA1
Mean 29.4
Standard deviation 3.9
Values 27 32
[24]
HepG2.C3A PPFIA1
Mean 22.1
Standard deviation 1.5
Values 23 21
[25]
HuH.7 PPFIA1
Mean 38.2
Standard deviation 5.1
Values 38 43 33
[26]
SNU475 PPFIA1
Mean 146
Standard deviation 15
Values 1.6e+02 1.4e+02
[27]
THLE PPFIA1
Mean 33.9
Standard deviation 4
Values 31 37
[28]
liver PPFIA1
Mean 22.1
Standard deviation 4.2
Values 21 25 16 25
[29]
ref_hepatocyte UNC13B
Mean 3.23
Standard deviation 1.4
Values 2.5 5.5 2.6 3.4 2.1
[30]
HepG2 UNC13B
Mean 24.3
Standard deviation 2.4
Values 23 26
[31]
HepG2.C3A UNC13B
Mean 23.4
Standard deviation 3.3
Values 26 21
[32]
HuH.7 UNC13B
Mean 35.5
Standard deviation 5.6
Values 40 37 29
[33]
SNU475 UNC13B
Mean 7.69
Standard deviation 1.6
Values 8.8 6.5
[34]
THLE UNC13B
Mean 13
Standard deviation 0.26
Values 13 13
[35]
liver UNC13B
Mean 27.3
Standard deviation 11
Values 17 41 19 33
[36]
ref_hepatocyte CASK
Mean 2.05
Standard deviation 0.81
Values 3 2.8 1.7 1.1 1.6
[37]
HepG2 CASK
Mean 15.8
Standard deviation 1
Values 17 15
[38]
HepG2.C3A CASK
Mean 13.2
Standard deviation 2
Values 15 12
[39]
HuH.7 CASK
Mean 36.8
Standard deviation 5.1
Values 36 42 32
[40]
SNU475 CASK
Mean 28.4
Standard deviation 8.4
Values 34 22
[41]
THLE CASK
Mean 19.6
Standard deviation 2.8
Values 22 18
[42]
liver CASK
Mean 6.96
Standard deviation 3
Values 6.1 8.6 3.2 9.9
[43]
ref_hepatocyte APBA1
Mean 1.5
Standard deviation 1.6
Values 0 3.6 2.7 0.47 0.71
[44]
HepG2 APBA1
Mean 0.0193
Standard deviation 0.003
Values 0.017 0.021
[45]
HepG2.C3A APBA1
Mean 0.0146
Standard deviation 0.021
Values 0.029 0
[46]
HuH.7 APBA1
Mean 7.4
Standard deviation 0.94
Values 8.5 7 6.7
[47]
SNU475 APBA1
Mean 0.641
Standard deviation 0.11
Values 0.72 0.56
[48]
THLE APBA1
Mean 0.474
Standard deviation 0.19
Values 0.34 0.61
[49]
liver APBA1
Mean 10.8
Standard deviation 5.3
Values 8.8 10 6 18
[50]
ref_hepatocyte LIN7B
Mean 0.899
Standard deviation 0.89
Values 1.6 0 0 1.9 0.98
[51]
HepG2 LIN7B
Mean 1.31
Standard deviation 0.28
Values 1.5 1.1
[52]
HepG2.C3A LIN7B
Mean 1.76
Standard deviation 0.76
Values 2.3 1.2
[53]
HuH.7 LIN7B
Mean 1.11
Standard deviation 0.26
Values 0.93 0.99 1.4
[54]
SNU475 LIN7B
Mean 0.98
Standard deviation 0.19
Values 1.1 0.85
[55]
THLE LIN7B
Mean 0.834
Standard deviation 0.13
Values 0.92 0.74
[56]
liver LIN7B
Mean 0.398
Standard deviation 0.34
Values 0.85 0.11 0.49 0.15
[57]
ref_hepatocyte RAB3A
Mean 0.786
Standard deviation 0.29
Values 0.95 0.55 0.49 0.76 1.2
[58]
HepG2 RAB3A
Mean 1.64
Standard deviation 0.46
Values 2 1.3
[59]
HepG2.C3A RAB3A
Mean 0.703
Standard deviation 0.33
Values 0.93 0.47
[60]
HuH.7 RAB3A
Mean 2.95
Standard deviation 0.48
Values 3.5 2.5 2.8
[61]
SNU475 RAB3A
Mean 0.823
Standard deviation 0.069
Values 0.77 0.87
[62]
THLE RAB3A
Mean 1.06
Standard deviation 0.15
Values 1.2 0.95
[63]
liver RAB3A
Mean 0.48
Standard deviation 0.46
Values 0.47 0.19 1.1 0.13
[64]
ref_hepatocyte SLC18A2
Mean 0.784
Standard deviation 0.93
Values 0 0 0.35 1.9 1.7
[65]
HepG2 SLC18A2
Mean 0.848
Standard deviation 0.11
Values 0.93 0.77
[66]
HepG2.C3A SLC18A2
Mean 3.83
Standard deviation 2.4
Values 5.5 2.2
[67]
HuH.7 SLC18A2
Mean 4.73
Standard deviation 0.58
Values 4.1 5.2 5
[68]
SNU475 SLC18A2
Mean 1.23
Standard deviation 0.21
Values 1.1 1.4
[69]
THLE SLC18A2
Mean 2.27
Standard deviation 1.1
Values 3 1.5
[70]
liver SLC18A2
Mean 10.9
Standard deviation 2.2
Values 14 9.4 9.1 11
[71]
ref_hepatocyte SYN1
Mean 0.678
Standard deviation 0.79
Values 0.038 0.036 0.98 1.9 0.43
[72]
HepG2 SYN1
Mean 0.317
Standard deviation 0.35
Values 0.56 0.073
[73]
HepG2.C3A SYN1
Mean 1.45
Standard deviation 0.014
Values 1.4 1.5
[74]
HuH.7 SYN1
Mean 0
Standard deviation 0
Values 0 0 0
[75]
SNU475 SYN1
Mean 0.105
Standard deviation 0.031
Values 0.083 0.13
[76]
THLE SYN1
Mean 1.81
Standard deviation 0.5
Values 2.2 1.5
[77]
liver SYN1
Mean 0.561
Standard deviation 0.32
Values 0.96 0.43 0.64 0.21
[78]
ref_hepatocyte STX1A
Mean 0.672
Standard deviation 0.98
Values 0.23 0.39 2.4 0.095 0.24
[79]
HepG2 STX1A
Mean 2.85
Standard deviation 0.85
Values 3.4 2.2
[80]
HepG2.C3A STX1A
Mean 2.48
Standard deviation 0.71
Values 3 2
[81]
HuH.7 STX1A
Mean 0.845
Standard deviation 0.25
Values 0.57 0.91 1.1
[82]
SNU475 STX1A
Mean 7.45
Standard deviation 3.6
Values 4.9 10
[83]
THLE STX1A
Mean 4.19
Standard deviation 1.3
Values 5.1 3.3
[84]
liver STX1A
Mean 0.426
Standard deviation 0.18
Values 0.35 0.31 0.69 0.34
[85]
ref_hepatocyte STXBP1
Mean 0.658
Standard deviation 0.63
Values 1.7 0.64 0.69 0.22 0.065
[86]
HepG2 STXBP1
Mean 4.83
Standard deviation 0.73
Values 5.4 4.3
[87]
HepG2.C3A STXBP1
Mean 5.71
Standard deviation 0.79
Values 6.3 5.1
[88]
HuH.7 STXBP1
Mean 7.36
Standard deviation 1.4
Values 8.9 6.5 6.7
[89]
SNU475 STXBP1
Mean 22.1
Standard deviation 0.72
Values 23 22
[90]
THLE STXBP1
Mean 22.4
Standard deviation 6
Values 18 27
[91]
liver STXBP1
Mean 1.67
Standard deviation 0.8
Values 2 1.1 2.6 0.91
[92]
ref_hepatocyte CPLX1
Mean 0.58
Standard deviation 0.61
Values 0.11 0 0.34 1.1 1.4
[93]
HepG2 CPLX1
Mean 0.678
Standard deviation 0.18
Values 0.8 0.55
[94]
HepG2.C3A CPLX1
Mean 0.29
Standard deviation 0.016
Values 0.3 0.28
[95]
HuH.7 CPLX1
Mean 7.91
Standard deviation 0.96
Values 9 7.3 7.4
[96]
SNU475 CPLX1
Mean 0.143
Standard deviation 0.012
Values 0.13 0.15
[97]
THLE CPLX1
Mean 0.156
Standard deviation 0.063
Values 0.2 0.11
[98]
liver CPLX1
Mean 0.943
Standard deviation 0.4
Values 0.73 1.3 0.49 1.3
[99]
ref_hepatocyte PPFIA3
Mean 0.55
Standard deviation 0.41
Values 1.1 0 0.71 0.53 0.39
[100]
HepG2 PPFIA3
Mean 8
Standard deviation 2.9
Values 10 6
[101]
HepG2.C3A PPFIA3
Mean 9.56
Standard deviation 2.5
Values 11 7.8
[102]
HuH.7 PPFIA3
Mean 9.06
Standard deviation 0.25
Values 9.3 9 8.8
[103]
SNU475 PPFIA3
Mean 1.88
Standard deviation 0.44
Values 1.6 2.2
[104]
THLE PPFIA3
Mean 1.58
Standard deviation 0.29
Values 1.8 1.4
[105]
liver PPFIA3
Mean 0.826
Standard deviation 0.32
Values 1 0.4 1.1 0.77
[106]
ref_hepatocyte SNAP25
Mean 0.146
Standard deviation 0.17
Values 0 0 0.3 0.069 0.36
[107]
HepG2 SNAP25
Mean 0.0286
Standard deviation 0.032
Values 0.0057 0.051
[108]
HepG2.C3A SNAP25
Mean 0.0292
Standard deviation 0.041
Values 0.058 0
[109]
HuH.7 SNAP25
Mean 1.43
Standard deviation 0.14
Values 1.4 1.3 1.6
[110]
SNU475 SNAP25
Mean 1.47
Standard deviation 0.63
Values 1 1.9
[111]
THLE SNAP25
Mean 6.82
Standard deviation 0.47
Values 7.1 6.5
[112]
liver SNAP25
Mean 0.427
Standard deviation 0.11
Values 0.42 0.34 0.36 0.58
[113]
ref_hepatocyte SYN3
Mean 0.0513
Standard deviation 0.11
Values 0.26 0 0 0 0
[114]
HepG2 SYN3
Mean 1.04
Standard deviation 0.36
Values 0.79 1.3
[115]
HepG2.C3A SYN3
Mean 3.25
Standard deviation 0.096
Values 3.2 3.3
[116]
HuH.7 SYN3
Mean 0.276
Standard deviation 0.078
Values 0.28 0.35 0.2
[117]
SNU475 SYN3
Mean 0
Standard deviation 0
Values 0 0
[118]
THLE SYN3
Mean 0.00532
Standard deviation 0.0075
Values 0 0.011
[119]
liver SYN3
Mean 0.0555
Standard deviation 0.034
Values 0.024 0.043 0.1 0.053
[120]
ref_hepatocyte SYT1
Mean 0.0375
Standard deviation 0.071
Values 0 0 0.16 0 0.024
[121]
HepG2 SYT1
Mean 0.0193
Standard deviation 0.021
Values 0.034 0.0043
[122]
HepG2.C3A SYT1
Mean 0.0102
Standard deviation 0.00071
Values 0.0097 0.011
[123]
HuH.7 SYT1
Mean 3.9
Standard deviation 1.6
Values 3.6 5.6 2.5
[124]
SNU475 SYT1
Mean 10
Standard deviation 0.7
Values 9.5 11
[125]
THLE SYT1
Mean 0.793
Standard deviation 0.075
Values 0.85 0.74
[126]
liver SYT1
Mean 0.992
Standard deviation 0.082
Values 0.94 1.1 0.98 0.94
[127]
ref_hepatocyte SYN2
Mean 0.00706
Standard deviation 0.016
Values 0.035 0 0 0 0
[128]
HepG2 SYN2
Mean 0.0115
Standard deviation 0.016
Values 0.023 0
[129]
HepG2.C3A SYN2
Mean 0.00972
Standard deviation 0.014
Values 0.019 0
[130]
HuH.7 SYN2
Mean 0.00642
Standard deviation 0.011
Values 0 0.019 0
[131]
SNU475 SYN2
Mean 0.133
Standard deviation 0.07
Values 0.083 0.18
[132]
THLE SYN2
Mean 0.235
Standard deviation 0.061
Values 0.28 0.19
[133]
liver SYN2
Mean 0.0349
Standard deviation 0.046
Values 0.024 0 0.1 0.013
[134]
ref_hepatocyte PPFIA2
Mean 0.00488
Standard deviation 0.011
Values 0 0 0 0 0.024
[135]
HepG2 PPFIA2
Mean 0.196
Standard deviation 0.026
Values 0.18 0.21
[136]
HepG2.C3A PPFIA2
Mean 1.33
Standard deviation 0.86
Values 1.9 0.72
[137]
HuH.7 PPFIA2
Mean 0.797
Standard deviation 0.16
Values 0.71 0.98 0.7
[138]
SNU475 PPFIA2
Mean 0.0148
Standard deviation 0.0078
Values 0.0093 0.02
[139]
THLE PPFIA2
Mean 0.0222
Standard deviation 0.0063
Values 0.018 0.027
[140]
liver PPFIA2
Mean 0.827
Standard deviation 0.62
Values 0.54 0.87 0.23 1.7
[141]
ref_hepatocyte PPFIA4
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[142]
HepG2 PPFIA4
Mean 1.54
Standard deviation 0.4
Values 1.3 1.8
[143]
HepG2.C3A PPFIA4
Mean 1.94
Standard deviation 0.4
Values 1.7 2.2
[144]
HuH.7 PPFIA4
Mean 3.04
Standard deviation 1.1
Values 2.1 4.2 2.9
[145]
SNU475 PPFIA4
Mean 5.33
Standard deviation 1.6
Values 6.5 4.2
[146]
THLE PPFIA4
Mean 2.71
Standard deviation 1.5
Values 3.8 1.6
[147]
liver PPFIA4
Mean 0.136
Standard deviation 0.079
Values 0.19 0.2 0.13 0.026
[148]
ref_hepatocyte TSPOAP1
Missing
[149]
HepG2 TSPOAP1
Missing
[150]
HepG2.C3A TSPOAP1
Missing
[151]
HuH.7 TSPOAP1
Missing
[152]
SNU475 TSPOAP1
Missing
[153]
THLE TSPOAP1
Missing
[154]
liver TSPOAP1
Missing
[155]
ref_hepatocyte RIMS1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[156]
HepG2 RIMS1
Mean 0
Standard deviation 0
Values 0 0
[157]
HepG2.C3A RIMS1
Mean 0
Standard deviation 0
Values 0 0
[158]
HuH.7 RIMS1
Mean 0
Standard deviation 0
Values 0 0 0
[159]
SNU475 RIMS1
Mean 0.0774
Standard deviation 0.002
Values 0.079 0.076
[160]
THLE RIMS1
Mean 0.0387
Standard deviation 0.013
Values 0.03 0.048
[161]
liver RIMS1
Mean 0.0607
Standard deviation 0.064
Values 0 0.071 0.026 0.15