REACTOME_DNA_REPLICATION_INITIATION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 POLE3 DNA polymerase epsilon subunit 3 [1] -0.64[2] -1.18[3] -0.75[4] -0.90[5] -0.42[6] -0.65[7]
2 POLE4 DNA polymerase epsilon subunit 4 [8] -0.90[9] -0.57[10] -3.88[11] -1.48[12] -2.50[13] -0.88[14]
3 POLA2 DNA polymerase alpha subunit B [15] 0.78[16] 0.02[17] 0.72[18] 1.67[19] 1.42[20] 0.09[21]
4 PRIM1 DNA primase small subunit [22] 0.81[23] 1.74[24] 2.21[25] 1.31[26] 1.35[27] 0.01[28]
5 PRIM2 DNA primase large subunit [29] 1.42[30] 0.83[31] 0.58[32] 1.33[33] 1.03[34] -0.66[35]
6 POLE DNA polymerase epsilon catalytic subunit A [36] 3.18[37] 3.41[38] 3.60[39] 2.89[40] 3.35[41] 3.86[42]
7 POLE2 DNA polymerase epsilon subunit 2 [43] 0.84[44] 1.24[45] 2.37[46] 1.31[47] 1.29[48] -0.23[49]
8 POLA1 DNA polymerase alpha catalytic subunit [50] 2.15[51] 1.86[52] 2.56[53] 3.14[54] 2.55[55] 2.59[56]
[1]
ref_hepatocyte POLE3
Mean 29.6
Standard deviation 21
Values 23 62 36 15 11
[2]
HepG2 POLE3
Mean 37.9
Standard deviation 13
Values 29 47
[3]
HepG2.C3A POLE3
Mean 30.6
Standard deviation 16
Values 19 42
[4]
HuH.7 POLE3
Mean 36
Standard deviation 15
Values 40 20 48
[5]
SNU475 POLE3
Mean 26.1
Standard deviation 0.99
Values 25 27
[6]
THLE POLE3
Mean 60
Standard deviation 7.2
Values 55 65
[7]
liver POLE3
Mean 14.1
Standard deviation 6.6
Values 15 11 23 7.8
[8]
ref_hepatocyte POLE4
Mean 27.1
Standard deviation 15
Values 28 15 9.6 45 38
[9]
HepG2 POLE4
Mean 28.9
Standard deviation 4.6
Values 26 32
[10]
HepG2.C3A POLE4
Mean 43
Standard deviation 18
Values 30 56
[11]
HuH.7 POLE4
Mean 3.76
Standard deviation 1.5
Values 3.8 2.3 5.3
[12]
SNU475 POLE4
Mean 16.1
Standard deviation 1
Values 17 15
[13]
THLE POLE4
Mean 13
Standard deviation 1.2
Values 12 14
[14]
liver POLE4
Mean 11
Standard deviation 11
Values 24 1.7 18 1.1
[15]
ref_hepatocyte POLA2
Mean 2.46
Standard deviation 0.96
Values 1.8 2.8 3.9 2.3 1.5
[16]
HepG2 POLA2
Mean 8.49
Standard deviation 2.2
Values 6.9 10
[17]
HepG2.C3A POLA2
Mean 5.87
Standard deviation 3.6
Values 3.3 8.4
[18]
HuH.7 POLA2
Mean 8.32
Standard deviation 5.1
Values 11 2.5 11
[19]
SNU475 POLA2
Mean 12.9
Standard deviation 3.1
Values 11 15
[20]
THLE POLA2
Mean 17.9
Standard deviation 4
Values 15 21
[21]
liver POLA2
Mean 1.96
Standard deviation 0.6
Values 1.2 1.9 2.6 2.2
[22]
ref_hepatocyte PRIM1
Mean 2.43
Standard deviation 1.4
Values 4.4 2.6 0.57 2.6 1.9
[23]
HepG2 PRIM1
Mean 8.54
Standard deviation 0.87
Values 7.9 9.2
[24]
HepG2.C3A PRIM1
Mean 19.1
Standard deviation 8.1
Values 13 25
[25]
HuH.7 PRIM1
Mean 23.1
Standard deviation 6.2
Values 27 16 26
[26]
SNU475 PRIM1
Mean 9.98
Standard deviation 3.1
Values 7.8 12
[27]
THLE PRIM1
Mean 16.8
Standard deviation 2.1
Values 15 18
[28]
liver PRIM1
Mean 1.84
Standard deviation 0.34
Values 2.1 1.6 2.1 1.5
[29]
ref_hepatocyte PRIM2
Mean 2.32
Standard deviation 2.3
Values 6.1 2.9 0.46 1.4 0.78
[30]
HepG2 PRIM2
Mean 12.4
Standard deviation 3.6
Values 9.9 15
[31]
HepG2.C3A PRIM2
Mean 9.66
Standard deviation 4.4
Values 6.5 13
[32]
HuH.7 PRIM2
Mean 7.1
Standard deviation 1.5
Values 7.8 5.4 8.1
[33]
SNU475 PRIM2
Mean 9.65
Standard deviation 1.6
Values 8.5 11
[34]
THLE PRIM2
Mean 12.8
Standard deviation 1.5
Values 12 14
[35]
liver PRIM2
Mean 1.1
Standard deviation 0.41
Values 0.68 1.5 0.82 1.4
[36]
ref_hepatocyte POLE
Mean 1.41
Standard deviation 0.61
Values 1.7 0.95 0.68 1.5 2.2
[37]
HepG2 POLE
Mean 25.6
Standard deviation 5.9
Values 22 30
[38]
HepG2.C3A POLE
Mean 35.2
Standard deviation 15
Values 24 46
[39]
HuH.7 POLE
Mean 35.1
Standard deviation 18
Values 50 15 40
[40]
SNU475 POLE
Mean 17.2
Standard deviation 0.14
Values 17 17
[41]
THLE POLE
Mean 39
Standard deviation 5
Values 35 43
[42]
liver POLE
Mean 15.3
Standard deviation 8.7
Values 11 19 6 25
[43]
ref_hepatocyte POLE2
Mean 1.24
Standard deviation 0.85
Values 1.7 2.2 0.24 1.6 0.46
[44]
HepG2 POLE2
Mean 4.44
Standard deviation 2.1
Values 3 5.9
[45]
HepG2.C3A POLE2
Mean 6.88
Standard deviation 5.4
Values 3.1 11
[46]
HuH.7 POLE2
Mean 13.1
Standard deviation 7.8
Values 15 4.4 20
[47]
SNU475 POLE2
Mean 5.05
Standard deviation 2
Values 3.6 6.4
[48]
THLE POLE2
Mean 8.23
Standard deviation 0.9
Values 7.6 8.9
[49]
liver POLE2
Mean 0.788
Standard deviation 0.23
Values 0.68 1 0.9 0.53
[50]
ref_hepatocyte POLA1
Mean 0.985
Standard deviation 0.81
Values 1.8 2 0.27 0.52 0.41
[51]
HepG2 POLA1
Mean 8.75
Standard deviation 4.7
Values 5.4 12
[52]
HepG2.C3A POLA1
Mean 8.42
Standard deviation 3.5
Values 5.9 11
[53]
HuH.7 POLA1
Mean 11.9
Standard deviation 5.3
Values 17 6.3 13
[54]
SNU475 POLA1
Mean 14.3
Standard deviation 5.6
Values 10 18
[55]
THLE POLA1
Mean 15.7
Standard deviation 1.1
Values 15 17
[56]
liver POLA1
Mean 4.45
Standard deviation 2.4
Values 1.9 7.6 3.5 4.8