REACTOME_DNA_DAMAGE_RECOGNITION_IN_GG_NER | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | ACTB | Actin, cytoplasmic 1 | [1] | -0.02[2] | -0.51[3] | -0.27[4] | 0.37[5] | -0.02[6] | 0.22[7] |
2 | UBB | Polyubiquitin-B | [8] | -0.83[9] | -0.84[10] | -1.08[11] | -1.42[12] | -0.96[13] | -0.47[14] |
3 | RPS27A | Ubiquitin-40S ribosomal protein S27a | [15] | [16] | [17] | [18] | [19] | [20] | [21] |
4 | UBC | Polyubiquitin-C | [22] | -0.39[23] | -0.08[24] | -0.71[25] | -0.57[26] | -0.59[27] | -0.02[28] |
5 | UBA52 | Ubiquitin-60S ribosomal protein L40 | [29] | 2.05[30] | 2.15[31] | 2.80[32] | 0.83[33] | 1.64[34] | 0.75[35] |
6 | RBX1 | E3 ubiquitin-protein ligase RBX1 | [36] | -0.69[37] | -0.06[38] | -0.57[39] | -1.35[40] | -0.92[41] | -0.69[42] |
7 | CETN2 | Centrin-2 | [43] | -1.24[44] | -0.66[45] | -2.22[46] | -1.30[47] | -1.73[48] | -2.08[49] |
8 | COPS6 | COP9 signalosome complex subunit 6 | [50] | 0.15[51] | 0.17[52] | -0.23[53] | 0.25[54] | 0.52[55] | -0.04[56] |
9 | PARP1 | Poly [ADP-ribose] polymerase 1 | [57] | 1.49[58] | 1.44[59] | 1.79[60] | 1.89[61] | 1.40[62] | 1.00[63] |
10 | RAD23B | UV excision repair protein RAD23 homolog B | [64] | 1.98[65] | 2.03[66] | 1.94[67] | 1.93[68] | 2.42[69] | 1.43[70] |
11 | RAD23A | UV excision repair protein RAD23 homolog A | [71] | 0.96[72] | 1.08[73] | 1.75[74] | 0.42[75] | 1.36[76] | 0.97[77] |
12 | DDB1 | DNA damage-binding protein 1 | [78] | 2.98[79] | 2.54[80] | 3.29[81] | 2.20[82] | 2.23[83] | 2.01[84] |
13 | GPS1 | COP9 signalosome complex subunit 1 | [85] | 1.95[86] | 2.16[87] | 1.00[88] | 1.18[89] | 1.09[90] | 1.23[91] |
14 | COPS5 | COP9 signalosome complex subunit 5 | [92] | 0.09[93] | 1.12[94] | 0.95[95] | 1.20[96] | 0.75[97] | 0.92[98] |
15 | COPS3 | COP9 signalosome complex subunit 3 | [99] | 1.05[100] | 1.35[101] | 1.39[102] | 1.51[103] | 1.55[104] | 0.27[105] |
16 | COPS7A | COP9 signalosome complex subunit 7a | [106] | 0.90[107] | 1.53[108] | 0.97[109] | 0.64[110] | 0.98[111] | 0.99[112] |
17 | CUL4A | Cullin-4A | [113] | 1.60[114] | 2.08[115] | 0.99[116] | 1.29[117] | 1.10[118] | 1.99[119] |
18 | COPS2 | COP9 signalosome complex subunit 2 | [120] | 0.54[121] | 2.72[122] | 2.56[123] | 1.68[124] | 1.89[125] | 1.01[126] |
19 | RUVBL1 | RuvB-like 1 | [127] | 1.79[128] | 1.60[129] | 1.32[130] | 0.71[131] | 1.40[132] | -0.06[133] |
20 | INO80C | INO80 complex subunit C | [134] | -0.89[135] | -0.30[136] | -1.00[137] | -0.55[138] | -1.26[139] | -1.70[140] |
21 | YY1 | Transcriptional repressor protein YY1 | [141] | 1.39[142] | 1.59[143] | 1.09[144] | 2.06[145] | 1.60[146] | 1.42[147] |
22 | ACTL6A | Actin-like protein 6A | [148] | 1.66[149] | 1.97[150] | 1.64[151] | 1.57[152] | 1.80[153] | 0.25[154] |
23 | INO80E | INO80 complex subunit E | [155] | 0.66[156] | 0.74[157] | 0.21[158] | -0.58[159] | -0.10[160] | -1.53[161] |
24 | MCRS1 | Microspherule protein 1 | [162] | 1.69[163] | 2.75[164] | 1.77[165] | 1.46[166] | 1.44[167] | 1.19[168] |
25 | PARP2 | Poly [ADP-ribose] polymerase 2 | [169] | 1.29[170] | 1.12[171] | 1.48[172] | 1.08[173] | 1.86[174] | -0.07[175] |
26 | COPS4 | COP9 signalosome complex subunit 4 | [176] | 0.84[177] | 2.02[178] | 1.52[179] | 1.19[180] | 1.42[181] | 0.97[182] |
27 | COPS8 | COP9 signalosome complex subunit 8 | [183] | 2.06[184] | 2.19[185] | 1.15[186] | 2.36[187] | 3.33[188] | 1.33[189] |
28 | TFPT | TCF3 fusion partner | [190] | -0.77[191] | -0.95[192] | -0.52[193] | -0.70[194] | 0.42[195] | -1.92[196] |
29 | INO80B | INO80 complex subunit B | [197] | -4.08[198] | -3.44[199] | -4.20[200] | -4.38[201] | -4.47[202] | -4.39[203] |
30 | CUL4B | Cullin-4B | [204] | 1.27[205] | 2.85[206] | 3.94[207] | 3.67[208] | 4.61[209] | 2.28[210] |
31 | DDB2 | DNA damage-binding protein 2 | [211] | 2.45[212] | 2.17[213] | 0.47[214] | -0.25[215] | 0.33[216] | -0.11[217] |
32 | COPS7B | COP9 signalosome complex subunit 7b | [218] | 2.32[219] | 2.91[220] | 2.44[221] | 1.97[222] | 2.01[223] | 0.77[224] |
33 | XPC | DNA repair protein complementing XP-C cells | [225] | 2.27[226] | 2.24[227] | 2.73[228] | 1.80[229] | 2.05[230] | 2.65[231] |
34 | ACTR8 | Actin-related protein 8 | [232] | 2.31[233] | 2.69[234] | 1.21[235] | 1.71[236] | 2.56[237] | 2.39[238] |
35 | INO80 | DNA helicase INO80 | [239] | 2.68[240] | 3.19[241] | 2.77[242] | 3.12[243] | 2.88[244] | 3.26[245] |
36 | ACTR5 | Actin-related protein 5 | [246] | 2.56[247] | 2.38[248] | 1.46[249] | 1.71[250] | 0.90[251] | 1.63[252] |
37 | NFRKB | Nuclear factor related to kappa-B-binding protein | [253] | 4.24[254] | 4.30[255] | 3.86[256] | 3.83[257] | 3.42[258] | 3.71[259] |
38 | INO80D | INO80 complex subunit D | [260] | 3.51[261] | 5.56[262] | 5.63[263] | 3.92[264] | 4.16[265] | 6.17[266] |