REACTOME_DNA_DAMAGE_BYPASS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 UBB Polyubiquitin-B [1] -0.99[2] -1.23[3] -1.28[4] -1.38[5] -1.14[6] -0.56[7]
2 RPS27A Ubiquitin-40S ribosomal protein S27a [8] [9] [10] [11] [12] [13] [14]
3 UBC Polyubiquitin-C [15] -0.55[16] -0.48[17] -0.91[18] -0.53[19] -0.76[20] -0.11[21]
4 VCP Transitional endoplasmic reticulum ATPase [22] 1.44[23] 1.14[24] 0.87[25] 0.90[26] 1.25[27] 1.56[28]
5 UBA52 Ubiquitin-60S ribosomal protein L40 [29] 1.89[30] 1.75[31] 2.60[32] 0.87[33] 1.47[34] 0.66[35]
6 RBX1 E3 ubiquitin-protein ligase RBX1 [36] -0.85[37] -0.46[38] -0.77[39] -1.31[40] -1.09[41] -0.78[42]
7 ISG15 Ubiquitin-like protein ISG15 [43] -0.95[44] -0.74[45] -2.05[46] -1.90[47] -3.25[48] -1.08[49]
8 UBE2L6 Ubiquitin/ISG15-conjugating enzyme E2 L6 [50] -0.54[51] -3.07[52] -1.61[53] 0.34[54] -0.44[55] 0.63[56]
9 PCNA Proliferating cell nuclear antigen [57] 2.09[58] 2.04[59] 0.44[60] 1.18[61] 1.25[62] -1.76[63]
10 POLD2 DNA polymerase delta subunit 2 [64] 0.61[65] 0.74[66] 1.06[67] 0.53[68] 0.69[69] 1.19[70]
11 POLD4 DNA polymerase delta subunit 4 [71] -0.92[72] -1.31[73] 0.58[74] 2.84[75] -0.96[76] 0.84[77]
12 DDB1 DNA damage-binding protein 1 [78] 2.82[79] 2.14[80] 3.09[81] 2.24[82] 2.06[83] 1.92[84]
13 POLE3 DNA polymerase epsilon subunit 3 [85] 0.42[86] 0.24[87] 0.34[88] 0.34[89] 1.17[90] -0.25[91]
14 POLE4 DNA polymerase epsilon subunit 4 [92] 0.16[93] 0.86[94] -2.79[95] -0.23[96] -0.91[97] -0.49[98]
15 RPA2 Replication protein A 32 kDa subunit [99] -0.25[100] -0.22[101] 0.15[102] 0.65[103] 0.52[104] -1.08[105]
16 MAD2L2 Mitotic spindle assembly checkpoint protein MAD2B [106] -0.33[107] 1.05[108] -0.42[109] -0.27[110] -0.27[111] -0.10[112]
17 UBE2B Ubiquitin-conjugating enzyme E2 B [113] 0.73[114] 1.13[115] 0.18[116] 0.81[117] 0.90[118] 0.60[119]
18 CUL4A Cullin-4A [120] 1.44[121] 1.68[122] 0.79[123] 1.33[124] 0.92[125] 1.90[126]
19 NPLOC4 Nuclear protein localization protein 4 homolog [127] 2.96[128] 2.49[129] 2.14[130] 2.87[131] 2.87[132] 2.61[133]
20 RFC4 Replication factor C subunit 4 [134] 0.24[135] 0.83[136] 1.21[137] 0.43[138] 1.55[139] -1.44[140]
21 USP10 Ubiquitin carboxyl-terminal hydrolase 10 [141] 2.06[142] 2.02[143] 2.14[144] 2.05[145] 2.14[146] 2.25[147]
22 RFC1 Replication factor C subunit 1 [148] 1.35[149] 2.60[150] 2.79[151] 1.72[152] 2.35[153] 2.10[154]
23 RFC2 Replication factor C subunit 2 [155] 0.94[156] 0.76[157] 0.61[158] 1.58[159] 1.82[160] 0.54[161]
24 RPA1 Replication protein A 70 kDa DNA-binding subunit [162] 2.52[163] 2.22[164] 2.30[165] 3.25[166] 3.05[167] 1.32[168]
25 RPA3 Replication protein A 14 kDa subunit [169] 0.84[170] 1.60[171] 2.13[172] 0.49[173] 0.57[174] 0.63[175]
26 CUL4B Cullin-4B [176] 1.11[177] 2.46[178] 3.74[179] 3.71[180] 4.43[181] 2.19[182]
27 TRIM25 E3 ubiquitin/ISG15 ligase TRIM25 [183] 3.34[184] 2.94[185] 2.58[186] 2.28[187] 2.72[188] 3.13[189]
28 RFC5 Replication factor C subunit 5 [190] 1.34[191] 1.76[192] 1.76[193] 1.66[194] 1.98[195] 0.44[196]
29 USP1 Ubiquitin carboxyl-terminal hydrolase 1 [197] 1.74[198] 3.10[199] 3.02[200] 3.17[201] 3.32[202] 1.65[203]
30 WDR48 WD repeat-containing protein 48 [204] 2.25[205] 3.08[206] 3.08[207] 1.89[208] 2.27[209] 2.54[210]
31 RFC3 Replication factor C subunit 3 [211] 2.38[212] 3.21[213] 3.15[214] 2.65[215] 3.03[216] 0.45[217]
32 UBA7 Ubiquitin-like modifier-activating enzyme 7 [218] 0.97[219] 0.66[220] -4.30[221] 2.46[222] 1.81[223] 2.70[224]
33 RCHY1 RING finger and CHY zinc finger domain-containing protein 1 [225] 1.90[226] 2.41[227] 1.62[228] 1.63[229] 2.15[230] 2.97[231]
34 POLD1 DNA polymerase delta catalytic subunit [232] 3.06[233] 3.25[234] 3.88[235] 3.22[236] 3.77[237] 1.98[238]
35 REV1 DNA repair protein REV1 [239] 2.64[240] 3.81[241] 2.90[242] 3.23[243] 2.98[244] 3.13[245]
36 POLK DNA polymerase kappa [246] 0.36[247] 1.80[248] 1.86[249] 3.23[250] 2.75[251] 3.41[252]
37 POLH DNA polymerase eta [253] 3.32[254] 2.78[255] 1.15[256] 3.40[257] 2.98[258] 2.65[259]
38 POLD3 DNA polymerase delta subunit 3 [260] 2.38[261] 2.21[262] 2.99[263] 3.51[264] 3.79[265] 2.30[266]
39 POLE DNA polymerase epsilon catalytic subunit A [267] 4.25[268] 4.83[269] 4.69[270] 4.13[271] 4.93[272] 4.25[273]
40 USP43 Ubiquitin carboxyl-terminal hydrolase 43 [274] 0.16[275] 1.02[276] -3.84[277] 1.23[278] -2.32[279] 1.59[280]
41 DTL Denticleless protein homolog [281] 3.44[282] 3.19[283] 3.91[284] 4.54[285] 4.23[286] 0.02[287]
42 POLE2 DNA polymerase epsilon subunit 2 [288] 1.91[289] 2.67[290] 3.46[291] 2.55[292] 2.88[293] 0.16[294]
43 RAD18 E3 ubiquitin-protein ligase RAD18 [295] 2.36[296] 3.51[297] 4.50[298] 3.76[299] 4.12[300] 2.32[301]
44 REV3L DNA polymerase zeta catalytic subunit [302] 3.61[303] 5.14[304] 3.56[305] 4.40[306] 4.32[307] 5.78[308]
45 POLI DNA polymerase iota [309] 2.79[310] 4.13[311] 3.85[312] 3.67[313] 3.24[314] 4.20[315]
46 UFD1 Ubiquitin recognition factor in ER-associated degradation protein 1 [316] [317] [318] [319] [320] [321] [322]
47 SPRTN SprT-like domain-containing protein Spartan [323] [324] [325] [326] [327] [328] [329]
48 PCLAF PCNA-associated factor [330] [331] [332] [333] [334] [335] [336]
[1]
ref_hepatocyte UBB
Mean 764
Standard deviation 4.8e+02
Values 3.8e+02 3.5e+02 5.3e+02 1.2e+03 1.3e+03
[2]
HepG2 UBB
Mean 368
Standard deviation 39
Values 4e+02 3.4e+02
[3]
HepG2.C3A UBB
Mean 285
Standard deviation 14
Values 2.8e+02 3e+02
[4]
HuH.7 UBB
Mean 304
Standard deviation 40
Values 2.9e+02 2.7e+02 3.5e+02
[5]
SNU475 UBB
Mean 204
Standard deviation 3.3
Values 2.1e+02 2e+02
[6]
THLE UBB
Mean 315
Standard deviation 34
Values 2.9e+02 3.4e+02
[7]
liver UBB
Mean 296
Standard deviation 1.3e+02
Values 4.3e+02 2.1e+02 3.9e+02 1.5e+02
[8]
ref_hepatocyte RPS27A
Mean 499
Standard deviation 2.2e+02
Values 6.6e+02 6.1e+02 1.7e+02 6.8e+02 3.8e+02
[9]
HepG2 RPS27A
Missing
[10]
HepG2.C3A RPS27A
Missing
[11]
HuH.7 RPS27A
Missing
[12]
SNU475 RPS27A
Missing
[13]
THLE RPS27A
Missing
[14]
liver RPS27A
Missing
[15]
ref_hepatocyte UBC
Mean 480
Standard deviation 2.8e+02
Values 1.8e+02 3.5e+02 9.1e+02 5.8e+02 3.8e+02
[16]
HepG2 UBC
Mean 314
Standard deviation 38
Values 3.4e+02 2.9e+02
[17]
HepG2.C3A UBC
Mean 302
Standard deviation 41
Values 3.3e+02 2.7e+02
[18]
HuH.7 UBC
Mean 246
Standard deviation 64
Values 2.4e+02 3.1e+02 1.9e+02
[19]
SNU475 UBC
Mean 232
Standard deviation 63
Values 2.8e+02 1.9e+02
[20]
THLE UBC
Mean 257
Standard deviation 41
Values 2.3e+02 2.9e+02
[21]
liver UBC
Mean 254
Standard deviation 78
Values 2.2e+02 3.1e+02 3.3e+02 1.6e+02
[22]
ref_hepatocyte VCP
Mean 91.1
Standard deviation 42
Values 1.1e+02 1.5e+02 85 65 46
[23]
HepG2 VCP
Mean 237
Standard deviation 12
Values 2.3e+02 2.5e+02
[24]
HepG2.C3A VCP
Mean 176
Standard deviation 5.6
Values 1.7e+02 1.8e+02
[25]
HuH.7 VCP
Mean 161
Standard deviation 23
Values 1.8e+02 1.3e+02 1.7e+02
[26]
SNU475 VCP
Mean 118
Standard deviation 15
Values 1.3e+02 1.1e+02
[27]
THLE VCP
Mean 196
Standard deviation 45
Values 1.6e+02 2.3e+02
[28]
liver VCP
Mean 153
Standard deviation 36
Values 1e+02 1.6e+02 1.8e+02 1.7e+02
[29]
ref_hepatocyte UBA52
Mean 57.3
Standard deviation 43
Values 14 23 49 1.2e+02 81
[30]
HepG2 UBA52
Mean 203
Standard deviation 20
Values 2.2e+02 1.9e+02
[31]
HepG2.C3A UBA52
Mean 169
Standard deviation 3.3
Values 1.7e+02 1.7e+02
[32]
HuH.7 UBA52
Mean 334
Standard deviation 46
Values 3.4e+02 2.8e+02 3.7e+02
[33]
SNU475 UBA52
Mean 72.9
Standard deviation 11
Values 65 81
[34]
THLE UBA52
Mean 144
Standard deviation 15
Values 1.3e+02 1.5e+02
[35]
liver UBA52
Mean 51.7
Standard deviation 26
Values 79 32 68 28
[36]
ref_hepatocyte RBX1
Mean 54.3
Standard deviation 41
Values 88 1.1e+02 7.4 33 36
[37]
HepG2 RBX1
Mean 28.8
Standard deviation 5.7
Values 25 33
[38]
HepG2.C3A RBX1
Mean 34.6
Standard deviation 13
Values 26 44
[39]
HuH.7 RBX1
Mean 30.6
Standard deviation 15
Values 29 17 46
[40]
SNU475 RBX1
Mean 15.3
Standard deviation 1.3
Values 16 14
[41]
THLE RBX1
Mean 23
Standard deviation 3.5
Values 21 25
[42]
liver RBX1
Mean 18
Standard deviation 18
Values 36 2.5 32 1.8
[43]
ref_hepatocyte ISG15
Mean 44.3
Standard deviation 26
Values 26 83 60 25 28
[44]
HepG2 ISG15
Mean 21.9
Standard deviation 6.9
Values 27 17
[45]
HepG2.C3A ISG15
Mean 23.2
Standard deviation 4.5
Values 26 20
[46]
HuH.7 ISG15
Mean 10.3
Standard deviation 1.4
Values 8.7 11 11
[47]
SNU475 ISG15
Mean 8.25
Standard deviation 2
Values 9.7 6.8
[48]
THLE ISG15
Mean 4.21
Standard deviation 0.34
Values 4.4 4
[49]
liver ISG15
Mean 11.9
Standard deviation 11
Values 23 3.7 20 0.57
[50]
ref_hepatocyte UBE2L6
Mean 36.8
Standard deviation 28
Values 12 18 20 67 66
[51]
HepG2 UBE2L6
Mean 24.1
Standard deviation 5.2
Values 28 20
[52]
HepG2.C3A UBE2L6
Mean 3.83
Standard deviation 0.84
Values 4.4 3.2
[53]
HuH.7 UBE2L6
Mean 11.6
Standard deviation 3.5
Values 9.6 16 9.5
[54]
SNU475 UBE2L6
Mean 32.5
Standard deviation 9.5
Values 39 26
[55]
THLE UBE2L6
Mean 24.6
Standard deviation 1.3
Values 24 25
[56]
liver UBE2L6
Mean 32.4
Standard deviation 29
Values 52 11 63 4.3
[57]
ref_hepatocyte PCNA
Mean 36
Standard deviation 33
Values 92 37 14 19 17
[58]
HepG2 PCNA
Mean 147
Standard deviation 54
Values 1.1e+02 1.9e+02
[59]
HepG2.C3A PCNA
Mean 130
Standard deviation 86
Values 69 1.9e+02
[60]
HuH.7 PCNA
Mean 46.8
Standard deviation 33
Values 53 10 76
[61]
SNU475 PCNA
Mean 56.8
Standard deviation 7.7
Values 51 62
[62]
THLE PCNA
Mean 77.4
Standard deviation 13
Values 68 86
[63]
liver PCNA
Mean 6.07
Standard deviation 2.5
Values 7.3 5.2 8.8 3
[64]
ref_hepatocyte POLD2
Mean 32.3
Standard deviation 18
Values 10 23 30 58 40
[65]
HepG2 POLD2
Mean 47
Standard deviation 5.6
Values 51 43
[66]
HepG2.C3A POLD2
Mean 47.2
Standard deviation 5.4
Values 43 51
[67]
HuH.7 POLD2
Mean 64.5
Standard deviation 25
Values 79 36 79
[68]
SNU475 POLD2
Mean 32.5
Standard deviation 4.3
Values 29 35
[69]
THLE POLD2
Mean 47.1
Standard deviation 7.9
Values 41 53
[70]
liver POLD2
Mean 42.1
Standard deviation 24
Values 67 21 57 23
[71]
ref_hepatocyte POLD4
Mean 31.5
Standard deviation 27
Values 1.6 16 19 64 57
[72]
HepG2 POLD4
Mean 15.9
Standard deviation 3.9
Values 19 13
[73]
HepG2.C3A POLD4
Mean 11.1
Standard deviation 4
Values 14 8.3
[74]
HuH.7 POLD4
Mean 45.1
Standard deviation 6.1
Values 39 51 46
[75]
SNU475 POLD4
Mean 157
Standard deviation 53
Values 1.9e+02 1.2e+02
[76]
THLE POLD4
Mean 14.6
Standard deviation 1.8
Values 13 16
[77]
liver POLD4
Mean 32.1
Standard deviation 32
Values 48 6 69 5.3
[78]
ref_hepatocyte DDB1
Mean 30
Standard deviation 15
Values 53 38 23 21 16
[79]
HepG2 DDB1
Mean 203
Standard deviation 1.9
Values 2e+02 2e+02
[80]
HepG2.C3A DDB1
Mean 116
Standard deviation 17
Values 1.3e+02 1e+02
[81]
HuH.7 DDB1
Mean 245
Standard deviation 45
Values 2.9e+02 2e+02 2.5e+02
[82]
SNU475 DDB1
Mean 98.5
Standard deviation 13
Values 1.1e+02 89
[83]
THLE DDB1
Mean 113
Standard deviation 22
Values 97 1.3e+02
[84]
liver DDB1
Mean 64.5
Standard deviation 20
Values 37 78 64 79
[85]
ref_hepatocyte POLE3
Mean 29.6
Standard deviation 21
Values 23 62 36 15 11
[86]
HepG2 POLE3
Mean 37.9
Standard deviation 13
Values 29 47
[87]
HepG2.C3A POLE3
Mean 30.6
Standard deviation 16
Values 19 42
[88]
HuH.7 POLE3
Mean 36
Standard deviation 15
Values 40 20 48
[89]
SNU475 POLE3
Mean 26.1
Standard deviation 0.99
Values 25 27
[90]
THLE POLE3
Mean 60
Standard deviation 7.2
Values 55 65
[91]
liver POLE3
Mean 14.1
Standard deviation 6.6
Values 15 11 23 7.8
[92]
ref_hepatocyte POLE4
Mean 27.1
Standard deviation 15
Values 28 15 9.6 45 38
[93]
HepG2 POLE4
Mean 28.9
Standard deviation 4.6
Values 26 32
[94]
HepG2.C3A POLE4
Mean 43
Standard deviation 18
Values 30 56
[95]
HuH.7 POLE4
Mean 3.76
Standard deviation 1.5
Values 3.8 2.3 5.3
[96]
SNU475 POLE4
Mean 16.1
Standard deviation 1
Values 17 15
[97]
THLE POLE4
Mean 13
Standard deviation 1.2
Values 12 14
[98]
liver POLE4
Mean 11
Standard deviation 11
Values 24 1.7 18 1.1
[99]
ref_hepatocyte RPA2
Mean 23.6
Standard deviation 12
Values 23 41 28 15 11
[100]
HepG2 RPA2
Mean 19
Standard deviation 3.9
Values 16 22
[101]
HepG2.C3A RPA2
Mean 17.8
Standard deviation 8.2
Values 12 24
[102]
HuH.7 RPA2
Mean 25.2
Standard deviation 11
Values 27 14 35
[103]
SNU475 RPA2
Mean 25.9
Standard deviation 7.9
Values 20 31
[104]
THLE RPA2
Mean 30.6
Standard deviation 2.7
Values 29 33
[105]
liver RPA2
Mean 6.36
Standard deviation 3.6
Values 6.9 4.2 11 3.2
[106]
ref_hepatocyte MAD2L2
Mean 23.4
Standard deviation 6.1
Values 16 26 23 32 20
[107]
HepG2 MAD2L2
Mean 17.9
Standard deviation 0.58
Values 18 17
[108]
HepG2.C3A MAD2L2
Mean 42.5
Standard deviation 1.7
Values 41 44
[109]
HuH.7 MAD2L2
Mean 16.8
Standard deviation 3.2
Values 17 13 20
[110]
SNU475 MAD2L2
Mean 13.5
Standard deviation 1.8
Values 12 15
[111]
THLE MAD2L2
Mean 17.6
Standard deviation 0.71
Values 18 17
[112]
liver MAD2L2
Mean 12.4
Standard deviation 8.8
Values 20 5.2 20 4.5
[113]
ref_hepatocyte UBE2B
Mean 17.5
Standard deviation 8.3
Values 28 25 10 10 14
[114]
HepG2 UBE2B
Mean 27.8
Standard deviation 4.1
Values 25 31
[115]
HepG2.C3A UBE2B
Mean 33.5
Standard deviation 2.1
Values 32 35
[116]
HuH.7 UBE2B
Mean 19.1
Standard deviation 1.6
Values 18 18 21
[117]
SNU475 UBE2B
Mean 21.4
Standard deviation 0.14
Values 21 21
[118]
THLE UBE2B
Mean 29.6
Standard deviation 0.41
Values 30 29
[119]
liver UBE2B
Mean 15.2
Standard deviation 13
Values 29 4.6 23 4.3
[120]
ref_hepatocyte CUL4A
Mean 16
Standard deviation 6.9
Values 19 27 13 9.6 12
[121]
HepG2 CUL4A
Mean 41.5
Standard deviation 1.9
Values 43 40
[122]
HepG2.C3A CUL4A
Mean 44.9
Standard deviation 3.6
Values 47 42
[123]
HuH.7 CUL4A
Mean 26.5
Standard deviation 5
Values 28 21 30
[124]
SNU475 CUL4A
Mean 27.9
Standard deviation 6.1
Values 32 24
[125]
THLE CUL4A
Mean 27.4
Standard deviation 7
Values 22 32
[126]
liver CUL4A
Mean 33.9
Standard deviation 5.6
Values 27 39 38 32
[127]
ref_hepatocyte NPLOC4
Mean 12.5
Standard deviation 6.6
Values 10 11 24 9.9 7
[128]
HepG2 NPLOC4
Mean 92.6
Standard deviation 0.83
Values 92 93
[129]
HepG2.C3A NPLOC4
Mean 61.3
Standard deviation 0.57
Values 61 62
[130]
HuH.7 NPLOC4
Mean 52.7
Standard deviation 8.9
Values 62 45 51
[131]
SNU475 NPLOC4
Mean 63.4
Standard deviation 6
Values 68 59
[132]
THLE NPLOC4
Mean 82.7
Standard deviation 2.2
Values 81 84
[133]
liver NPLOC4
Mean 43.3
Standard deviation 2.6
Values 44 42 40 46
[134]
ref_hepatocyte RFC4
Mean 11
Standard deviation 7.9
Values 17 21 9.8 4.7 2.4
[135]
HepG2 RFC4
Mean 12.4
Standard deviation 2.7
Values 10 14
[136]
HepG2.C3A RFC4
Mean 17
Standard deviation 7.7
Values 12 22
[137]
HuH.7 RFC4
Mean 24.4
Standard deviation 12
Values 26 12 35
[138]
SNU475 RFC4
Mean 10.3
Standard deviation 3.5
Values 7.8 13
[139]
THLE RFC4
Mean 29.1
Standard deviation 0.079
Values 29 29
[140]
liver RFC4
Mean 2.31
Standard deviation 1.2
Values 2.3 1.9 4 1
[141]
ref_hepatocyte USP10
Mean 10.9
Standard deviation 1.3
Values 11 12 13 9.3 10
[142]
HepG2 USP10
Mean 43.4
Standard deviation 5.5
Values 39 47
[143]
HepG2.C3A USP10
Mean 38.5
Standard deviation 1.4
Values 38 40
[144]
HuH.7 USP10
Mean 46.1
Standard deviation 12
Values 58 35 46
[145]
SNU475 USP10
Mean 31.3
Standard deviation 1.3
Values 30 32
[146]
THLE USP10
Mean 43.4
Standard deviation 2.1
Values 42 45
[147]
liver USP10
Mean 29.5
Standard deviation 12
Values 36 21 43 19
[148]
ref_hepatocyte RFC1
Mean 9.26
Standard deviation 5.4
Values 15 15 7.1 4.1 5
[149]
HepG2 RFC1
Mean 22.5
Standard deviation 11
Values 15 30
[150]
HepG2.C3A RFC1
Mean 49.1
Standard deviation 4.6
Values 46 52
[151]
HuH.7 RFC1
Mean 61.4
Standard deviation 8.8
Values 66 67 51
[152]
SNU475 RFC1
Mean 21.2
Standard deviation 2
Values 20 23
[153]
THLE RFC1
Mean 42.7
Standard deviation 3.9
Values 45 40
[154]
liver RFC1
Mean 22.6
Standard deviation 3.4
Values 24 26 18 23
[155]
ref_hepatocyte RFC2
Mean 8.95
Standard deviation 3.2
Values 7.3 13 6.2 11 6.5
[156]
HepG2 RFC2
Mean 16.5
Standard deviation 2.8
Values 14 18
[157]
HepG2.C3A RFC2
Mean 13.3
Standard deviation 5.7
Values 9.3 17
[158]
HuH.7 RFC2
Mean 13.1
Standard deviation 6.2
Values 15 6.1 18
[159]
SNU475 RFC2
Mean 18.6
Standard deviation 4.4
Values 16 22
[160]
THLE RFC2
Mean 28.7
Standard deviation 3.4
Values 26 31
[161]
liver RFC2
Mean 7.44
Standard deviation 4.1
Values 10 4.9 11 3.1
[162]
ref_hepatocyte RPA1
Mean 8.25
Standard deviation 3.9
Values 9.2 15 5.5 5.3 6.7
[163]
HepG2 RPA1
Mean 45.3
Standard deviation 8.3
Values 39 51
[164]
HepG2.C3A RPA1
Mean 33.6
Standard deviation 11
Values 26 41
[165]
HuH.7 RPA1
Mean 39
Standard deviation 14
Values 47 23 48
[166]
SNU475 RPA1
Mean 54.6
Standard deviation 1
Values 55 54
[167]
THLE RPA1
Mean 62.1
Standard deviation 11
Values 54 70
[168]
liver RPA1
Mean 11.7
Standard deviation 1.8
Values 12 12 14 9.5
[169]
ref_hepatocyte RPA3
Mean 8.22
Standard deviation 4.8
Values 6.2 7.6 1.9 11 15
[170]
HepG2 RPA3
Mean 14.1
Standard deviation 4
Values 11 17
[171]
HepG2.C3A RPA3
Mean 21.8
Standard deviation 13
Values 13 31
[172]
HuH.7 RPA3
Mean 34.5
Standard deviation 16
Values 35 18 50
[173]
SNU475 RPA3
Mean 8.05
Standard deviation 1.5
Values 9.1 7
[174]
THLE RPA3
Mean 11
Standard deviation 2.9
Values 8.9 13
[175]
liver RPA3
Mean 7.22
Standard deviation 6.1
Values 13 2.4 12 1.4
[176]
ref_hepatocyte CUL4B
Mean 6.58
Standard deviation 3.6
Values 10 11 4.5 3.6 3.8
[177]
HepG2 CUL4B
Mean 13.6
Standard deviation 5.6
Values 9.6 18
[178]
HepG2.C3A CUL4B
Mean 31.7
Standard deviation 1.7
Values 30 33
[179]
HuH.7 CUL4B
Mean 84.7
Standard deviation 18
Values 81 1e+02 69
[180]
SNU475 CUL4B
Mean 59.9
Standard deviation 7.1
Values 65 55
[181]
THLE CUL4B
Mean 129
Standard deviation 4.1
Values 1.3e+02 1.3e+02
[182]
liver CUL4B
Mean 17.1
Standard deviation 4.3
Values 14 23 15 17
[183]
ref_hepatocyte TRIM25
Mean 6.54
Standard deviation 4.3
Values 10 11 7.2 2.2 1.9
[184]
HepG2 TRIM25
Mean 63.4
Standard deviation 2.6
Values 65 62
[185]
HepG2.C3A TRIM25
Mean 43.9
Standard deviation 3.5
Values 41 46
[186]
HuH.7 TRIM25
Mean 37.6
Standard deviation 5.8
Values 42 39 31
[187]
SNU475 TRIM25
Mean 22.1
Standard deviation 1.8
Values 23 21
[188]
THLE TRIM25
Mean 39
Standard deviation 5.5
Values 35 43
[189]
liver TRIM25
Mean 32.7
Standard deviation 17
Values 20 44 16 51
[190]
ref_hepatocyte RFC5
Mean 5.54
Standard deviation 4.9
Values 13 7.4 0.42 3.6 3.2
[191]
HepG2 RFC5
Mean 13.4
Standard deviation 5.4
Values 9.6 17
[192]
HepG2.C3A RFC5
Mean 16.4
Standard deviation 10
Values 9 24
[193]
HuH.7 RFC5
Mean 18.1
Standard deviation 6.8
Values 23 10 21
[194]
SNU475 RFC5
Mean 12.2
Standard deviation 2.4
Values 11 14
[195]
THLE RFC5
Mean 19.8
Standard deviation 2.4
Values 18 22
[196]
liver RFC5
Mean 4.29
Standard deviation 1.7
Values 4.9 3.5 6.3 2.5
[197]
ref_hepatocyte USP1
Mean 4.86
Standard deviation 3.9
Values 11 5.8 2.6 2.1 2.4
[198]
HepG2 USP1
Mean 15.6
Standard deviation 8.3
Values 9.7 21
[199]
HepG2.C3A USP1
Mean 36.5
Standard deviation 17
Values 25 48
[200]
HuH.7 USP1
Mean 38
Standard deviation 11
Values 46 26 42
[201]
SNU475 USP1
Mean 30.5
Standard deviation 6.2
Values 26 35
[202]
THLE USP1
Mean 44
Standard deviation 2.6
Values 46 42
[203]
liver USP1
Mean 8.7
Standard deviation 1.6
Values 10 9.6 8.4 6.5
[204]
ref_hepatocyte WDR48
Mean 3.72
Standard deviation 0.86
Values 4.8 3.8 4.3 2.9 2.9
[205]
HepG2 WDR48
Mean 17
Standard deviation 4.7
Values 14 20
[206]
HepG2.C3A WDR48
Mean 27.4
Standard deviation 4.4
Values 31 24
[207]
HuH.7 WDR48
Mean 30.1
Standard deviation 1.1
Values 31 30 29
[208]
SNU475 WDR48
Mean 9.62
Standard deviation 1.2
Values 10 8.8
[209]
THLE WDR48
Mean 16.2
Standard deviation 0.42
Values 16 17
[210]
liver WDR48
Mean 12.3
Standard deviation 2.1
Values 11 15 12 11
[211]
ref_hepatocyte RFC3
Mean 3.17
Standard deviation 3.1
Values 6.3 6.7 1.4 0.35 1.1
[212]
HepG2 RFC3
Mean 15.8
Standard deviation 7.8
Values 10 21
[213]
HepG2.C3A RFC3
Mean 25.6
Standard deviation 17
Values 14 37
[214]
HuH.7 RFC3
Mean 27.1
Standard deviation 12
Values 35 14 33
[215]
SNU475 RFC3
Mean 13.8
Standard deviation 3.5
Values 11 16
[216]
THLE RFC3
Mean 23.5
Standard deviation 5.4
Values 20 27
[217]
liver RFC3
Mean 2.46
Standard deviation 0.85
Values 2 2.9 3.4 1.5
[218]
ref_hepatocyte UBA7
Mean 2.86
Standard deviation 2.5
Values 0.39 0.77 2.1 5.2 5.8
[219]
HepG2 UBA7
Mean 5.36
Standard deviation 0.4
Values 5.1 5.6
[220]
HepG2.C3A UBA7
Mean 3.96
Standard deviation 2
Values 5.4 2.5
[221]
HuH.7 UBA7
Mean 0.14
Standard deviation 0.0083
Values 0.15 0.14 0.13
[222]
SNU475 UBA7
Mean 11
Standard deviation 6.3
Values 15 6.5
[223]
THLE UBA7
Mean 9.05
Standard deviation 0.65
Values 9.5 8.6
[224]
liver UBA7
Mean 10.6
Standard deviation 1.5
Values 9 10 11 12
[225]
ref_hepatocyte RCHY1
Mean 2.47
Standard deviation 1.3
Values 1.9 4.3 0.8 2.6 2.9
[226]
HepG2 RCHY1
Mean 8.81
Standard deviation 2.8
Values 6.9 11
[227]
HepG2.C3A RCHY1
Mean 11.5
Standard deviation 6.2
Values 7.1 16
[228]
HuH.7 RCHY1
Mean 7.32
Standard deviation 0.8
Values 7.8 6.4 7.7
[229]
SNU475 RCHY1
Mean 5.34
Standard deviation 0.092
Values 5.3 5.4
[230]
THLE RCHY1
Mean 9.95
Standard deviation 0.6
Values 10 9.5
[231]
liver RCHY1
Mean 11
Standard deviation 2.7
Values 14 9.4 13 8
[232]
ref_hepatocyte POLD1
Mean 2.41
Standard deviation 0.8
Values 2 3.5 2.7 2.4 1.4
[233]
HepG2 POLD1
Mean 19.3
Standard deviation 1.9
Values 21 18
[234]
HepG2.C3A POLD1
Mean 20.1
Standard deviation 2.3
Values 18 22
[235]
HuH.7 POLD1
Mean 34
Standard deviation 15
Values 42 16 44
[236]
SNU475 POLD1
Mean 15.6
Standard deviation 2.9
Values 14 18
[237]
THLE POLD1
Mean 29.7
Standard deviation 2.6
Values 28 32
[238]
liver POLD1
Mean 5.43
Standard deviation 0.68
Values 6.2 4.7 5.8 5.1
[239]
ref_hepatocyte REV1
Mean 2.22
Standard deviation 1.2
Values 4.1 2.1 0.84 2.2 1.9
[240]
HepG2 REV1
Mean 13.3
Standard deviation 2.7
Values 11 15
[241]
HepG2.C3A REV1
Mean 27.3
Standard deviation 3.9
Values 30 25
[242]
HuH.7 REV1
Mean 15.9
Standard deviation 2
Values 16 14 18
[243]
SNU475 REV1
Mean 14.5
Standard deviation 0.93
Values 15 14
[244]
THLE REV1
Mean 15.9
Standard deviation 0.38
Values 16 16
[245]
liver REV1
Mean 11.1
Standard deviation 2.7
Values 11 12 7.4 14
[246]
ref_hepatocyte POLK
Mean 2.2
Standard deviation 1.6
Values 1 4.7 2.2 0.59 2.5
[247]
HepG2 POLK
Mean 2.71
Standard deviation 0.4
Values 2.4 3
[248]
HepG2.C3A POLK
Mean 6.72
Standard deviation 1.5
Values 5.7 7.8
[249]
HuH.7 POLK
Mean 7.69
Standard deviation 1.2
Values 8.1 8.7 6.3
[250]
SNU475 POLK
Mean 14.4
Standard deviation 1
Values 15 14
[251]
THLE POLK
Mean 13.4
Standard deviation 2.8
Values 15 11
[252]
liver POLK
Mean 13.4
Standard deviation 3.4
Values 11 18 11 13
[253]
ref_hepatocyte POLH
Mean 2.19
Standard deviation 1.9
Values 3.7 4.8 0.8 0.88 0.81
[254]
HepG2 POLH
Mean 20.9
Standard deviation 1
Values 22 20
[255]
HepG2.C3A POLH
Mean 13.1
Standard deviation 4.8
Values 9.7 17
[256]
HuH.7 POLH
Mean 4.66
Standard deviation 0.78
Values 5.4 3.9 4.7
[257]
SNU475 POLH
Mean 16.1
Standard deviation 2.4
Values 18 14
[258]
THLE POLH
Mean 15.6
Standard deviation 0.66
Values 15 16
[259]
liver POLH
Mean 7.84
Standard deviation 1.4
Values 5.7 8.9 8.1 8.7
[260]
ref_hepatocyte POLD3
Mean 1.46
Standard deviation 0.56
Values 1.9 1.9 1 1.8 0.71
[261]
HepG2 POLD3
Mean 7.29
Standard deviation 0.95
Values 6.6 8
[262]
HepG2.C3A POLD3
Mean 5.94
Standard deviation 4
Values 3.1 8.8
[263]
HuH.7 POLD3
Mean 11.2
Standard deviation 6.1
Values 15 4.1 14
[264]
SNU475 POLD3
Mean 11.6
Standard deviation 3.7
Values 9 14
[265]
THLE POLD3
Mean 18.3
Standard deviation 1.6
Values 17 19
[266]
liver POLD3
Mean 4.11
Standard deviation 1.1
Values 3.6 4.3 5.6 3
[267]
ref_hepatocyte POLE
Mean 1.41
Standard deviation 0.61
Values 1.7 0.95 0.68 1.5 2.2
[268]
HepG2 POLE
Mean 25.6
Standard deviation 5.9
Values 22 30
[269]
HepG2.C3A POLE
Mean 35.2
Standard deviation 15
Values 24 46
[270]
HuH.7 POLE
Mean 35.1
Standard deviation 18
Values 50 15 40
[271]
SNU475 POLE
Mean 17.2
Standard deviation 0.14
Values 17 17
[272]
THLE POLE
Mean 39
Standard deviation 5
Values 35 43
[273]
liver POLE
Mean 15.3
Standard deviation 8.7
Values 11 19 6 25
[274]
ref_hepatocyte USP43
Mean 1.32
Standard deviation 0.96
Values 0.059 2 2.4 1.5 0.64
[275]
HepG2 USP43
Mean 1.42
Standard deviation 0.17
Values 1.3 1.5
[276]
HepG2.C3A USP43
Mean 2.36
Standard deviation 0.31
Values 2.1 2.6
[277]
HuH.7 USP43
Mean 0.0885
Standard deviation 0.038
Values 0.057 0.077 0.13
[278]
SNU475 USP43
Mean 2.16
Standard deviation 0.89
Values 2.8 1.5
[279]
THLE USP43
Mean 0.24
Standard deviation 0.054
Values 0.28 0.2
[280]
liver USP43
Mean 2.28
Standard deviation 1.8
Values 0.87 2.2 1.3 4.8
[281]
ref_hepatocyte DTL
Mean 1.28
Standard deviation 1.4
Values 3.6 1.7 0.28 0.51 0.25
[282]
HepG2 DTL
Mean 13.3
Standard deviation 6.2
Values 8.9 18
[283]
HepG2.C3A DTL
Mean 10.2
Standard deviation 6.7
Values 5.4 15
[284]
HuH.7 DTL
Mean 18.4
Standard deviation 11
Values 28 6.1 22
[285]
SNU475 DTL
Mean 20.7
Standard deviation 7
Values 16 26
[286]
THLE DTL
Mean 21.7
Standard deviation 2.1
Values 20 23
[287]
liver DTL
Mean 0.741
Standard deviation 0.61
Values 0.33 1 1.5 0.16
[288]
ref_hepatocyte POLE2
Mean 1.24
Standard deviation 0.85
Values 1.7 2.2 0.24 1.6 0.46
[289]
HepG2 POLE2
Mean 4.44
Standard deviation 2.1
Values 3 5.9
[290]
HepG2.C3A POLE2
Mean 6.88
Standard deviation 5.4
Values 3.1 11
[291]
HuH.7 POLE2
Mean 13.1
Standard deviation 7.8
Values 15 4.4 20
[292]
SNU475 POLE2
Mean 5.05
Standard deviation 2
Values 3.6 6.4
[293]
THLE POLE2
Mean 8.23
Standard deviation 0.9
Values 7.6 8.9
[294]
liver POLE2
Mean 0.788
Standard deviation 0.23
Values 0.68 1 0.9 0.53
[295]
ref_hepatocyte RAD18
Mean 0.959
Standard deviation 0.59
Values 1.1 1.9 0.76 0.63 0.4
[296]
HepG2 RAD18
Mean 4.69
Standard deviation 2
Values 3.3 6.1
[297]
HepG2.C3A RAD18
Mean 9.56
Standard deviation 5.6
Values 5.6 13
[298]
HuH.7 RAD18
Mean 20.9
Standard deviation 7.1
Values 28 13 22
[299]
SNU475 RAD18
Mean 9.06
Standard deviation 2.7
Values 7.2 11
[300]
THLE RAD18
Mean 15
Standard deviation 0.74
Values 15 16
[301]
liver RAD18
Mean 2.73
Standard deviation 0.4
Values 2.4 3.3 2.5 2.7
[302]
ref_hepatocyte REV3L
Mean 0.797
Standard deviation 0.43
Values 1.5 0.87 0.81 0.35 0.49
[303]
HepG2 REV3L
Mean 9.34
Standard deviation 3.8
Values 6.6 12
[304]
HepG2.C3A REV3L
Mean 24.6
Standard deviation 4.9
Values 21 28
[305]
HuH.7 REV3L
Mean 9.03
Standard deviation 2.1
Values 11 9.5 6.7
[306]
SNU475 REV3L
Mean 11.7
Standard deviation 0.59
Values 12 11
[307]
THLE REV3L
Mean 14.5
Standard deviation 4.7
Values 18 11
[308]
liver REV3L
Mean 25
Standard deviation 9.5
Values 21 36 14 28
[309]
ref_hepatocyte POLI
Mean 0.576
Standard deviation 0.41
Values 1.1 0.34 0.11 0.47 0.82
[310]
HepG2 POLI
Mean 3.8
Standard deviation 1.1
Values 3 4.6
[311]
HepG2.C3A POLI
Mean 8.84
Standard deviation 0.22
Values 9 8.7
[312]
HuH.7 POLI
Mean 7.98
Standard deviation 0.05
Values 8 8 7.9
[313]
SNU475 POLI
Mean 5.09
Standard deviation 1.6
Values 6.2 3.9
[314]
THLE POLI
Mean 4.92
Standard deviation 0.31
Values 5.1 4.7
[315]
liver POLI
Mean 6.01
Standard deviation 1.2
Values 6.9 6.8 6.1 4.2
[316]
ref_hepatocyte UFD1
Missing
[317]
HepG2 UFD1
Missing
[318]
HepG2.C3A UFD1
Missing
[319]
HuH.7 UFD1
Missing
[320]
SNU475 UFD1
Missing
[321]
THLE UFD1
Missing
[322]
liver UFD1
Missing
[323]
ref_hepatocyte SPRTN
Missing
[324]
HepG2 SPRTN
Mean 4.98
Standard deviation 0.34
Values 4.7 5.2
[325]
HepG2.C3A SPRTN
Mean 4.92
Standard deviation 1.9
Values 3.6 6.2
[326]
HuH.7 SPRTN
Mean 6.97
Standard deviation 1.2
Values 8.1 5.7 7.1
[327]
SNU475 SPRTN
Mean 9.18
Standard deviation 0.11
Values 9.3 9.1
[328]
THLE SPRTN
Mean 8.18
Standard deviation 0.24
Values 8 8.4
[329]
liver SPRTN
Mean 5.28
Standard deviation 0.37
Values 4.9 5.1 5.8 5.4
[330]
ref_hepatocyte PCLAF
Missing
[331]
HepG2 PCLAF
Missing
[332]
HepG2.C3A PCLAF
Missing
[333]
HuH.7 PCLAF
Missing
[334]
SNU475 PCLAF
Missing
[335]
THLE PCLAF
Missing
[336]
liver PCLAF
Missing