REACTOME_DISPLACEMENT_OF_DNA_GLYCOSYLASE_BY_APEX1 Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 APEX1 DNA-(apurinic or apyrimidinic site) lyase [1] 0.25[2] -0.23[3] 0.36[4] -0.10[5] -0.40[6] -0.76[7]
2 MPG DNA-3-methyladenine glycosylase [8] -0.52[9] 0.08[10] -1.34[11] -1.62[12] -1.02[13] -0.59[14]
3 NTHL1 Endonuclease III-like protein 1 [15] -1.05[16] -0.77[17] -1.84[18] -1.56[19] -1.72[20] 0.49[21]
4 UNG Uracil-DNA glycosylase [22] 0.67[23] 0.49[24] 0.60[25] -0.40[26] 0.40[27] -0.18[28]
5 SMUG1 Single-strand selective monofunctional uracil DNA glycosylase [29] -0.62[30] -0.52[31] -0.80[32] 0.13[33] -0.29[34] 0.31[35]
6 MBD4 Methyl-CpG-binding domain protein 4 [36] -0.54[37] 0.05[38] 0.15[39] 1.08[40] 1.89[41] 1.68[42]
7 TDG G/T mismatch-specific thymine DNA glycosylase [43] -0.16[44] 0.73[45] 0.14[46] 2.23[47] 1.64[48] 0.83[49]
8 OGG1 N-glycosylase/DNA lyase [50] 0.58[51] 0.55[52] 0.33[53] 0.12[54] 0.03[55] 0.19[56]
9 MUTYH Adenine DNA glycosylase [57] 0.44[58] 1.34[59] 1.88[60] 0.63[61] 0.85[62] 0.85[63]
[1]
ref_hepatocyte APEX1
Mean 47.5
Standard deviation 8.3
Values 54 48 56 42 37
[2]
HepG2 APEX1
Mean 112
Standard deviation 14
Values 1.2e+02 1e+02
[3]
HepG2.C3A APEX1
Mean 78.4
Standard deviation 5.9
Values 83 74
[4]
HuH.7 APEX1
Mean 142
Standard deviation 16
Values 1.4e+02 1.3e+02 1.6e+02
[5]
SNU475 APEX1
Mean 49.7
Standard deviation 2
Values 48 51
[6]
THLE APEX1
Mean 43.8
Standard deviation 9.3
Values 37 50
[7]
liver APEX1
Mean 21.1
Standard deviation 12
Values 32 12 31 9.4
[8]
ref_hepatocyte MPG
Mean 22.1
Standard deviation 13
Values 8.3 7.8 30 34 30
[9]
HepG2 MPG
Mean 30.5
Standard deviation 3.2
Values 33 28
[10]
HepG2.C3A MPG
Mean 45.2
Standard deviation 11
Values 53 37
[11]
HuH.7 MPG
Mean 20.3
Standard deviation 5.2
Values 17 18 26
[12]
SNU475 MPG
Mean 8.08
Standard deviation 2.7
Values 10 6.2
[13]
THLE MPG
Mean 13.3
Standard deviation 0.76
Values 13 14
[14]
liver MPG
Mean 11
Standard deviation 7.1
Values 17 4.8 18 4.9
[15]
ref_hepatocyte NTHL1
Mean 14.1
Standard deviation 13
Values 7.6 7.2 3.3 16 36
[16]
HepG2 NTHL1
Mean 13.5
Standard deviation 2.5
Values 15 12
[17]
HepG2.C3A NTHL1
Mean 15.9
Standard deviation 2.4
Values 18 14
[18]
HuH.7 NTHL1
Mean 9.15
Standard deviation 4.4
Values 10 4.4 13
[19]
SNU475 NTHL1
Mean 5.36
Standard deviation 0.58
Values 5.8 4.9
[20]
THLE NTHL1
Mean 5.19
Standard deviation 0.11
Values 5.3 5.1
[21]
liver NTHL1
Mean 14.8
Standard deviation 17
Values 38 1.7 18 1.5
[22]
ref_hepatocyte UNG
Mean 14
Standard deviation 7.2
Values 24 18 6.5 10 10
[23]
HepG2 UNG
Mean 43.9
Standard deviation 13
Values 35 53
[24]
HepG2.C3A UNG
Mean 38
Standard deviation 15
Values 27 49
[25]
HuH.7 UNG
Mean 49.1
Standard deviation 30
Values 63 15 70
[26]
SNU475 UNG
Mean 11.9
Standard deviation 0.64
Values 11 12
[27]
THLE UNG
Mean 22.5
Standard deviation 6.3
Values 18 27
[28]
liver UNG
Mean 9.31
Standard deviation 5.9
Values 14 5.1 15 3.5
[29]
ref_hepatocyte SMUG1
Mean 12
Standard deviation 10
Values 2.5 5.4 6.3 21 25
[30]
HepG2 SMUG1
Mean 15.4
Standard deviation 0.94
Values 16 15
[31]
HepG2.C3A SMUG1
Mean 16.1
Standard deviation 4.9
Values 13 20
[32]
HuH.7 SMUG1
Mean 16
Standard deviation 4.3
Values 17 11 20
[33]
SNU475 SMUG1
Mean 14.7
Standard deviation 0.46
Values 15 14
[34]
THLE SMUG1
Mean 11.9
Standard deviation 0.94
Values 11 13
[35]
liver SMUG1
Mean 11.2
Standard deviation 6.4
Values 17 6.2 17 5
[36]
ref_hepatocyte MBD4
Mean 5.95
Standard deviation 2
Values 3.1 6.1 6.5 8.7 5.4
[37]
HepG2 MBD4
Mean 8.07
Standard deviation 3.5
Values 5.6 11
[38]
HepG2.C3A MBD4
Mean 11.9
Standard deviation 2
Values 11 13
[39]
HuH.7 MBD4
Mean 15.4
Standard deviation 2.9
Values 15 13 18
[40]
SNU475 MBD4
Mean 14.1
Standard deviation 2.2
Values 13 16
[41]
THLE MBD4
Mean 26.9
Standard deviation 3
Values 29 25
[42]
liver MBD4
Mean 14.4
Standard deviation 6.2
Values 19 12 19 6.4
[43]
ref_hepatocyte TDG
Mean 5.86
Standard deviation 3.8
Values 8 11 4.6 3.2 2.1
[44]
HepG2 TDG
Mean 10.4
Standard deviation 2.7
Values 8.5 12
[45]
HepG2.C3A TDG
Mean 18.9
Standard deviation 2.3
Values 17 20
[46]
HuH.7 TDG
Mean 15.1
Standard deviation 1.1
Values 15 14 16
[47]
SNU475 TDG
Mean 30.9
Standard deviation 3.6
Values 33 28
[48]
THLE TDG
Mean 22.3
Standard deviation 2.4
Values 21 24
[49]
liver TDG
Mean 7.85
Standard deviation 2.4
Values 9.6 6 10 5.6
[50]
ref_hepatocyte OGG1
Mean 5.01
Standard deviation 2.4
Values 4.1 2.4 6.9 8.1 3.6
[51]
HepG2 OGG1
Mean 14.8
Standard deviation 0.85
Values 14 15
[52]
HepG2.C3A OGG1
Mean 14.2
Standard deviation 2.8
Values 12 16
[53]
HuH.7 OGG1
Mean 14.7
Standard deviation 4.7
Values 17 9.2 18
[54]
SNU475 OGG1
Mean 6.11
Standard deviation 0.72
Values 5.6 6.6
[55]
THLE OGG1
Mean 6.23
Standard deviation 1.1
Values 5.5 7
[56]
liver OGG1
Mean 4.3
Standard deviation 1.9
Values 7.1 3.7 3.8 2.6
[57]
ref_hepatocyte MUTYH
Mean 1.95
Standard deviation 0.95
Values 0.9 1.1 2.9 2.8 2.1
[58]
HepG2 MUTYH
Mean 5.23
Standard deviation 0.6
Values 5.7 4.8
[59]
HepG2.C3A MUTYH
Mean 9.52
Standard deviation 1.5
Values 11 8.5
[60]
HuH.7 MUTYH
Mean 16.7
Standard deviation 4.8
Values 16 12 22
[61]
SNU475 MUTYH
Mean 3.39
Standard deviation 1.2
Values 2.6 4.2
[62]
THLE MUTYH
Mean 4.29
Standard deviation 0.4
Values 4.6 4
[63]
liver MUTYH
Mean 2.66
Standard deviation 1.1
Values 3.8 1.7 3.4 1.8