REACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS |
Return to index |
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Order |
Gene |
Description |
ref_hepatocyte |
HepG2 |
HepG2.C3A |
HuH.7 |
SNU475 |
THLE |
liver |
1 |
FGG |
Fibrinogen gamma chain |
[1] |
-5.10[2] |
-4.04[3] |
-3.87[4] |
-11.56[5] |
-13.44[6] |
-0.45[7] |
2 |
FGA |
Fibrinogen alpha chain |
[8] |
-4.76[9] |
-4.28[10] |
-3.77[11] |
-10.77[12] |
-13.46[13] |
0.22[14] |
3 |
FGB |
Fibrinogen beta chain |
[15] |
-5.97[16] |
-5.06[17] |
-2.78[18] |
-8.90[19] |
-12.09[20] |
1.01[21] |
4 |
ACTB |
Actin, cytoplasmic 1 |
[22] |
0.11[23] |
-0.48[24] |
0.04[25] |
0.73[26] |
0.35[27] |
-1.07[28] |
5 |
RPS6 |
40S ribosomal protein S6 |
[29] |
[30] |
[31] |
[32] |
[33] |
[34] |
[35] |
6 |
UBB |
Polyubiquitin-B |
[36] |
-0.70[37] |
-0.81[38] |
-0.76[39] |
-1.06[40] |
-0.59[41] |
-1.76[42] |
7 |
NPM1 |
Nucleophosmin |
[43] |
-0.39[44] |
0.56[45] |
1.15[46] |
-0.75[47] |
-0.72[48] |
-3.83[49] |
8 |
ACTG1 |
Actin, cytoplasmic 2 |
[50] |
1.39[51] |
0.16[52] |
0.16[53] |
0.54[54] |
0.94[55] |
-1.82[56] |
9 |
PEBP1 |
Phosphatidylethanolamine-binding protein 1 |
[57] |
-0.35[58] |
0.10[59] |
-1.01[60] |
-3.07[61] |
-2.48[62] |
-0.61[63] |
10 |
SQSTM1 |
Sequestosome-1 |
[64] |
-0.26[65] |
-1.22[66] |
-0.77[67] |
0.55[68] |
0.47[69] |
-1.68[70] |
11 |
RPS27A |
Ubiquitin-40S ribosomal protein S27a |
[71] |
[72] |
[73] |
[74] |
[75] |
[76] |
[77] |
12 |
UBC |
Polyubiquitin-C |
[78] |
-0.26[79] |
-0.06[80] |
-0.39[81] |
-0.20[82] |
-0.21[83] |
-1.31[84] |
13 |
EEF1G |
Elongation factor 1-gamma |
[85] |
1.31[86] |
1.66[87] |
1.98[88] |
0.31[89] |
0.58[90] |
-2.22[91] |
14 |
HSP90AA1 |
Heat shock protein HSP 90-alpha |
[92] |
0.85[93] |
1.91[94] |
1.05[95] |
1.81[96] |
1.51[97] |
-1.14[98] |
15 |
PSME1 |
Proteasome activator complex subunit 1 |
[99] |
-0.03[100] |
-1.65[101] |
-1.37[102] |
-0.92[103] |
-1.43[104] |
-2.26[105] |
16 |
FN1 |
Fibronectin |
[106] |
4.99[107] |
4.56[108] |
4.35[109] |
4.64[110] |
4.85[111] |
2.41[112] |
17 |
TPM4 |
Tropomyosin alpha-4 chain |
[113] |
1.34[114] |
0.65[115] |
0.62[116] |
1.57[117] |
2.19[118] |
-2.80[119] |
18 |
PSME2 |
Proteasome activator complex subunit 2 |
[120] |
0.15[121] |
-1.27[122] |
-1.45[123] |
-0.71[124] |
-0.97[125] |
-1.89[126] |
19 |
PSMA7 |
Proteasome subunit alpha type-7 |
[127] |
1.11[128] |
1.20[129] |
-0.21[130] |
0.92[131] |
0.50[132] |
-0.86[133] |
20 |
PSMB1 |
Proteasome subunit beta type-1 |
[134] |
0.66[135] |
0.75[136] |
-0.40[137] |
-0.33[138] |
0.46[139] |
-1.03[140] |
21 |
PSMB3 |
Proteasome subunit beta type-3 |
[141] |
0.17[142] |
-0.63[143] |
0.32[144] |
-0.35[145] |
-0.44[146] |
-1.32[147] |
22 |
RAP1B |
Ras-related protein Rap-1b |
[148] |
-0.81[149] |
-0.10[150] |
-0.42[151] |
1.20[152] |
0.96[153] |
-1.78[154] |
23 |
PSMB4 |
Proteasome subunit beta type-4 |
[155] |
0.42[156] |
0.57[157] |
0.62[158] |
1.08[159] |
1.10[160] |
-1.65[161] |
24 |
PSMB7 |
Proteasome subunit beta type-7 |
[162] |
-0.53[163] |
-0.53[164] |
-0.48[165] |
-0.69[166] |
-0.22[167] |
-2.09[168] |
25 |
PSMB5 |
Proteasome subunit beta type-5 |
[169] |
1.87[170] |
0.43[171] |
0.28[172] |
0.03[173] |
0.34[174] |
-1.62[175] |
26 |
MSN |
Moesin |
[176] |
-6.59[177] |
-8.80[178] |
-7.59[179] |
2.72[180] |
1.74[181] |
-1.16[182] |
27 |
VCP |
Transitional endoplasmic reticulum ATPase |
[183] |
1.73[184] |
1.56[185] |
1.39[186] |
1.22[187] |
1.79[188] |
0.36[189] |
28 |
MYH9 |
Myosin-9 |
[190] |
2.92[191] |
1.45[192] |
1.32[193] |
2.94[194] |
2.84[195] |
0.51[196] |
29 |
TPM3 |
Tropomyosin alpha-3 chain |
[197] |
1.32[198] |
1.09[199] |
1.67[200] |
2.16[201] |
1.77[202] |
-0.78[203] |
30 |
PSMA6 |
Proteasome subunit alpha type-6 |
[204] |
2.00[205] |
0.71[206] |
0.56[207] |
0.56[208] |
0.60[209] |
-1.53[210] |
31 |
OS9 |
Protein OS-9 |
[211] |
0.74[212] |
1.24[213] |
0.89[214] |
0.11[215] |
0.36[216] |
0.08[217] |
32 |
LMNA |
Prelamin-A/C |
[218] |
1.36[219] |
0.90[220] |
-0.58[221] |
2.24[222] |
1.48[223] |
-0.85[224] |
33 |
FKBP1A |
Peptidyl-prolyl cis-trans isomerase FKBP1A |
[225] |
1.38[226] |
1.07[227] |
-0.59[228] |
1.46[229] |
1.06[230] |
-1.26[231] |
34 |
PSMA4 |
Proteasome subunit alpha type-4 |
[232] |
0.07[233] |
0.72[234] |
0.44[235] |
0.86[236] |
0.72[237] |
-1.61[238] |
35 |
SKP1 |
S-phase kinase-associated protein 1 |
[239] |
0.52[240] |
1.00[241] |
0.03[242] |
1.22[243] |
1.45[244] |
-0.58[245] |
36 |
PSMC3 |
26S proteasome regulatory subunit 6A |
[246] |
0.04[247] |
-0.04[248] |
0.50[249] |
-0.34[250] |
-0.11[251] |
-1.14[252] |
37 |
PSMA3 |
Proteasome subunit alpha type-3 |
[253] |
-0.55[254] |
0.44[255] |
-0.31[256] |
0.41[257] |
-0.01[258] |
-1.36[259] |
38 |
PSMB6 |
Proteasome subunit beta type-6 |
[260] |
0.00[261] |
0.14[262] |
0.20[263] |
-0.14[264] |
-0.37[265] |
-1.21[266] |
39 |
CDC37 |
Hsp90 co-chaperone Cdc37 |
[267] |
0.74[268] |
0.18[269] |
0.45[270] |
-0.08[271] |
0.50[272] |
-1.87[273] |
40 |
PSMA2 |
Proteasome subunit alpha type-2 |
[274] |
-0.09[275] |
0.86[276] |
1.12[277] |
0.36[278] |
0.76[279] |
-0.98[280] |
41 |
PHB |
Prohibitin |
[281] |
1.58[282] |
1.56[283] |
0.89[284] |
0.47[285] |
0.49[286] |
-0.89[287] |
42 |
PSMD4 |
26S proteasome non-ATPase regulatory subunit 4 |
[288] |
0.43[289] |
0.44[290] |
0.56[291] |
1.06[292] |
0.56[293] |
-1.31[294] |
43 |
PSMD7 |
26S proteasome non-ATPase regulatory subunit 7 |
[295] |
0.35[296] |
0.71[297] |
0.49[298] |
-0.03[299] |
0.48[300] |
-1.48[301] |
44 |
PSMD8 |
26S proteasome non-ATPase regulatory subunit 8 |
[302] |
0.52[303] |
0.75[304] |
0.81[305] |
0.25[306] |
1.04[307] |
-1.46[308] |
45 |
POLR2L |
DNA-directed RNA polymerases I, II, and III subunit RPABC5 |
[309] |
-0.98[310] |
-0.89[311] |
-1.23[312] |
-0.47[313] |
-0.53[314] |
-1.22[315] |
46 |
PSMD2 |
26S proteasome non-ATPase regulatory subunit 2 |
[316] |
2.05[317] |
1.22[318] |
1.21[319] |
1.36[320] |
2.69[321] |
-0.42[322] |
47 |
PSMC1 |
26S proteasome regulatory subunit 4 |
[323] |
0.37[324] |
0.43[325] |
-0.30[326] |
1.54[327] |
1.10[328] |
-1.26[329] |
48 |
PSMA1 |
Proteasome subunit alpha type-1 |
[330] |
0.55[331] |
0.94[332] |
0.92[333] |
1.12[334] |
0.65[335] |
-0.77[336] |
49 |
UBA52 |
Ubiquitin-60S ribosomal protein L40 |
[337] |
2.18[338] |
2.18[339] |
3.12[340] |
1.19[341] |
2.02[342] |
-0.54[343] |
50 |
PSMC5 |
26S proteasome regulatory subunit 8 |
[344] |
0.87[345] |
0.76[346] |
0.76[347] |
0.53[348] |
0.97[349] |
-1.00[350] |
51 |
RBX1 |
E3 ubiquitin-protein ligase RBX1 |
[351] |
-0.56[352] |
-0.04[353] |
-0.25[354] |
-0.98[355] |
-0.55[356] |
-1.98[357] |
52 |
RAC1 |
Ras-related C3 botulinum toxin substrate 1 |
[358] |
1.10[359] |
0.87[360] |
1.48[361] |
1.74[362] |
1.73[363] |
-0.85[364] |
53 |
PRKAR1A |
cAMP-dependent protein kinase type I-alpha regulatory subunit |
[365] |
1.57[366] |
1.79[367] |
1.84[368] |
1.63[369] |
1.54[370] |
0.71[371] |
54 |
PSMD3 |
26S proteasome non-ATPase regulatory subunit 3 |
[372] |
1.27[373] |
0.75[374] |
1.27[375] |
1.06[376] |
1.31[377] |
-1.29[378] |
55 |
PSMB8 |
Proteasome subunit beta type-8 |
[379] |
-1.13[380] |
-1.73[381] |
-9.02[382] |
1.03[383] |
-0.24[384] |
-1.98[385] |
56 |
PSMD14 |
26S proteasome non-ATPase regulatory subunit 14 |
[386] |
0.45[387] |
1.04[388] |
1.22[389] |
0.92[390] |
0.99[391] |
-1.43[392] |
57 |
PSMC4 |
26S proteasome regulatory subunit 6B |
[393] |
0.87[394] |
0.89[395] |
0.75[396] |
0.55[397] |
0.70[398] |
-0.95[399] |
58 |
PSMD6 |
26S proteasome non-ATPase regulatory subunit 6 |
[400] |
-0.28[401] |
0.19[402] |
-0.97[403] |
-0.07[404] |
0.77[405] |
-1.54[406] |
59 |
RRBP1 |
Ribosome-binding protein 1 |
[407] |
1.92[408] |
2.41[409] |
2.61[410] |
1.40[411] |
1.19[412] |
0.87[413] |
60 |
YWHAB |
14-3-3 protein beta/alpha |
[414] |
2.53[415] |
2.34[416] |
1.52[417] |
3.02[418] |
2.47[419] |
0.02[420] |
61 |
TFG |
Protein TFG |
[421] |
0.50[422] |
0.51[423] |
1.16[424] |
1.13[425] |
1.00[426] |
-0.48[427] |
62 |
PSMD13 |
26S proteasome non-ATPase regulatory subunit 13 |
[428] |
0.92[429] |
1.02[430] |
1.44[431] |
0.98[432] |
0.53[433] |
-1.36[434] |
63 |
CDKN1A |
Cyclin-dependent kinase inhibitor 1 |
[435] |
2.34[436] |
1.04[437] |
-1.75[438] |
-0.26[439] |
2.30[440] |
-1.72[441] |
64 |
PSMD12 |
26S proteasome non-ATPase regulatory subunit 12 |
[442] |
0.10[443] |
0.17[444] |
-0.22[445] |
0.60[446] |
0.70[447] |
-1.44[448] |
65 |
SND1 |
Staphylococcal nuclease domain-containing protein 1 |
[449] |
2.37[450] |
2.55[451] |
3.00[452] |
2.01[453] |
1.59[454] |
1.15[455] |
66 |
JUNB |
Transcription factor jun-B |
[456] |
-0.46[457] |
-1.23[458] |
-0.62[459] |
-0.44[460] |
0.41[461] |
-1.27[462] |
67 |
AKT1 |
RAC-alpha serine/threonine-protein kinase |
[463] |
1.58[464] |
1.44[465] |
0.26[466] |
1.67[467] |
1.70[468] |
-0.13[469] |
68 |
POLR2J |
DNA-directed RNA polymerase II subunit RPB11-a |
[470] |
-1.67[471] |
-1.29[472] |
-1.11[473] |
-1.70[474] |
-1.36[475] |
-2.97[476] |
69 |
CEBPB |
CCAAT/enhancer-binding protein beta |
[477] |
0.32[478] |
-0.22[479] |
-0.29[480] |
0.31[481] |
1.25[482] |
-1.56[483] |
70 |
CTNNB1 |
Catenin beta-1 |
[484] |
3.12[485] |
2.70[486] |
3.49[487] |
2.48[488] |
2.71[489] |
1.22[490] |
71 |
PSMC6 |
26S proteasome regulatory subunit 10B |
[491] |
0.39[492] |
1.96[493] |
0.70[494] |
0.96[495] |
0.93[496] |
-0.78[497] |
72 |
PSMD11 |
26S proteasome non-ATPase regulatory subunit 11 |
[498] |
1.27[499] |
0.88[500] |
1.39[501] |
1.37[502] |
1.56[503] |
0.04[504] |
73 |
APH1A |
Gamma-secretase subunit APH-1A |
[505] |
1.43[506] |
1.80[507] |
1.92[508] |
1.46[509] |
1.36[510] |
-0.90[511] |
74 |
PPP1CB |
Serine/threonine-protein phosphatase PP1-beta catalytic subunit |
[512] |
1.26[513] |
1.91[514] |
1.91[515] |
2.48[516] |
2.31[517] |
0.61[518] |
75 |
PSMC2 |
26S proteasome regulatory subunit 7 |
[519] |
1.03[520] |
1.42[521] |
1.12[522] |
1.76[523] |
1.63[524] |
0.10[525] |
76 |
STAT3 |
Signal transducer and activator of transcription 3 |
[526] |
2.05[527] |
0.64[528] |
1.28[529] |
1.96[530] |
1.25[531] |
2.52[532] |
77 |
CLTC |
Clathrin heavy chain 1 |
[533] |
3.11[534] |
3.30[535] |
3.38[536] |
3.40[537] |
3.55[538] |
2.57[539] |
78 |
MYC |
Myc proto-oncogene protein |
[540] |
1.93[541] |
1.68[542] |
-0.45[543] |
-1.07[544] |
1.31[545] |
-1.88[546] |
79 |
CALM1 |
Calmodulin-1 |
[547] |
1.57[548] |
1.70[549] |
2.06[550] |
3.31[551] |
2.59[552] |
1.73[553] |
80 |
MAP2K1 |
Dual specificity mitogen-activated protein kinase kinase 1 |
[554] |
0.57[555] |
0.33[556] |
0.81[557] |
1.18[558] |
1.70[559] |
-1.08[560] |
81 |
PPP2R1A |
Serine/threonine-protein phosphatase
2A 65 kDa regulatory subunit A alpha isoform |
2.30[561] |
2.21[562] |
2.04[563] |
2.93[564] |
2.27[565] |
0.26[566] |
82 |
POLR2E |
DNA-directed RNA polymerases I, II, and III subunit RPABC1 |
[567] |
2.10[568] |
2.15[569] |
2.14[570] |
1.16[571] |
2.03[572] |
0.60[573] |
83 |
DERL2 |
Derlin-2 |
[574] |
-0.73[575] |
0.01[576] |
-0.61[577] |
0.02[578] |
-0.23[579] |
-1.06[580] |
84 |
MAP2K2 |
Dual specificity mitogen-activated protein kinase kinase 2 |
[581] |
1.55[582] |
1.32[583] |
2.09[584] |
0.88[585] |
1.38[586] |
-1.59[587] |
85 |
PSME3 |
Proteasome activator complex subunit 3 |
[588] |
2.26[589] |
1.97[590] |
1.57[591] |
1.79[592] |
2.09[593] |
-0.34[594] |
86 |
POLR2H |
DNA-directed RNA polymerases I, II, and III subunit RPABC3 |
[595] |
-0.08[596] |
0.64[597] |
0.51[598] |
-0.95[599] |
-0.25[600] |
-1.84[601] |
87 |
PPP2CA |
Serine/threonine-protein phosphatase
2A catalytic subunit alpha isoform |
1.77[602] |
1.95[603] |
1.22[604] |
2.46[605] |
2.59[606] |
0.01[607] |
88 |
CCNC |
Cyclin-C |
[608] |
0.57[609] |
2.05[610] |
1.46[611] |
0.64[612] |
0.88[613] |
0.01[614] |
89 |
PPP1CC |
Serine/threonine-protein phosphatase
PP1-gamma catalytic subunit |
2.17[615] |
3.05[616] |
3.17[617] |
1.96[618] |
2.07[619] |
-0.96[620] |
90 |
PSENEN |
Gamma-secretase subunit PEN-2 |
[621] |
-0.57[622] |
-0.46[623] |
-0.09[624] |
-0.16[625] |
-0.57[626] |
-1.95[627] |
91 |
BCL2L1 |
Bcl-2-like protein 1 |
[628] |
3.64[629] |
3.12[630] |
3.98[631] |
1.11[632] |
1.50[633] |
-0.70[634] |
92 |
SPTBN1 |
Spectrin beta chain, non-erythrocytic 1 |
[635] |
4.25[636] |
3.88[637] |
4.18[638] |
3.13[639] |
3.48[640] |
3.07[641] |
93 |
PPP2CB |
Serine/threonine-protein phosphatase
2A catalytic subunit beta isoform |
1.10[642] |
0.85[643] |
0.83[644] |
1.27[645] |
1.17[646] |
-0.87[647] |
94 |
SNW1 |
SNW domain-containing protein 1 |
[648] |
0.50[649] |
0.76[650] |
0.68[651] |
1.59[652] |
1.35[653] |
-1.52[654] |
95 |
ATIC |
Bifunctional purine biosynthesis protein PURH |
[655] |
2.64[656] |
2.58[657] |
2.43[658] |
1.35[659] |
1.68[660] |
-1.15[661] |
96 |
POLR2F |
DNA-directed RNA polymerases I, II, and III subunit RPABC2 |
[662] |
0.23[663] |
0.56[664] |
-0.36[665] |
-0.88[666] |
-0.13[667] |
-0.95[668] |
97 |
POLR2K |
DNA-directed RNA polymerases I, II, and III subunit RPABC4 |
[669] |
-0.09[670] |
0.85[671] |
0.65[672] |
0.77[673] |
0.69[674] |
-1.16[675] |
98 |
POLR2G |
DNA-directed RNA polymerase II subunit RPB7 |
[676] |
0.33[677] |
0.71[678] |
0.10[679] |
0.57[680] |
0.45[681] |
-1.71[682] |
99 |
PSMD1 |
26S proteasome non-ATPase regulatory subunit 1 |
[683] |
2.02[684] |
2.33[685] |
2.13[686] |
2.59[687] |
2.64[688] |
0.85[689] |
100 |
GTF2F2 |
General transcription factor IIF subunit 2 |
[690] |
-0.45[691] |
0.28[692] |
0.49[693] |
-0.40[694] |
-0.16[695] |
-2.47[696] |
101 |
PTPN11 |
Tyrosine-protein phosphatase non-receptor type 11 |
[697] |
1.94[698] |
2.47[699] |
2.32[700] |
2.61[701] |
3.25[702] |
1.37[703] |
102 |
PSMB10 |
Proteasome subunit beta type-10 |
[704] |
-0.71[705] |
-0.12[706] |
-2.09[707] |
0.38[708] |
-0.75[709] |
-1.30[710] |
103 |
NCBP2 |
Nuclear cap-binding protein subunit 2 |
[711] |
1.03[712] |
1.59[713] |
1.57[714] |
0.85[715] |
1.12[716] |
-1.22[717] |
104 |
HDAC1 |
Histone deacetylase 1 |
[718] |
2.00[719] |
2.11[720] |
2.70[721] |
2.37[722] |
2.16[723] |
-0.35[724] |
105 |
CTBP1 |
C-terminal-binding protein 1 |
[725] |
1.55[726] |
1.75[727] |
1.93[728] |
2.13[729] |
1.19[730] |
-0.15[731] |
106 |
CSNK1A1 |
Casein kinase I isoform alpha |
[732] |
1.84[733] |
1.92[734] |
1.59[735] |
2.56[736] |
2.66[737] |
0.81[738] |
107 |
GRB2 |
Growth factor receptor-bound protein 2 |
[739] |
2.69[740] |
2.62[741] |
2.64[742] |
2.28[743] |
2.20[744] |
0.41[745] |
108 |
YES1 |
Tyrosine-protein kinase Yes |
[746] |
0.64[747] |
2.22[748] |
2.34[749] |
2.17[750] |
1.64[751] |
0.24[752] |
109 |
STAT1 |
Signal transducer and activator of transcription 1-alpha/beta |
[753] |
1.42[754] |
0.60[755] |
1.61[756] |
4.25[757] |
2.00[758] |
1.07[759] |
110 |
SYVN1 |
E3 ubiquitin-protein ligase synoviolin |
[760] |
0.53[761] |
0.95[762] |
0.45[763] |
0.32[764] |
0.46[765] |
0.53[766] |
111 |
PSMA5 |
Proteasome subunit alpha type-5 |
[767] |
2.35[768] |
2.76[769] |
2.25[770] |
2.65[771] |
2.24[772] |
0.69[773] |
112 |
PSMF1 |
Proteasome inhibitor PI31 subunit |
[774] |
2.72[775] |
2.76[776] |
1.49[777] |
1.66[778] |
1.45[779] |
0.63[780] |
113 |
LRRFIP1 |
Leucine-rich repeat flightless-interacting protein 1 |
[781] |
0.84[782] |
1.44[783] |
0.63[784] |
1.37[785] |
1.98[786] |
0.80[787] |
114 |
MAPKAP1 |
Target of rapamycin complex 2 subunit MAPKAP1 |
[788] |
1.49[789] |
1.33[790] |
1.45[791] |
1.80[792] |
2.00[793] |
-0.07[794] |
115 |
SEC31A |
Protein transport protein Sec31A |
[795] |
3.28[796] |
3.36[797] |
3.34[798] |
2.75[799] |
2.71[800] |
1.78[801] |
116 |
POLR2C |
DNA-directed RNA polymerase II subunit RPB3 |
[802] |
2.32[803] |
2.52[804] |
1.91[805] |
1.48[806] |
1.73[807] |
-0.34[808] |
117 |
PPM1B |
Protein phosphatase 1B |
[809] |
-0.12[810] |
0.67[811] |
0.54[812] |
0.23[813] |
0.59[814] |
-0.01[815] |
118 |
ERLEC1 |
Endoplasmic reticulum lectin 1 |
[816] |
1.25[817] |
2.88[818] |
2.41[819] |
1.57[820] |
1.46[821] |
0.08[822] |
119 |
RAP1A |
Ras-related protein Rap-1A |
[823] |
0.45[824] |
0.48[825] |
1.22[826] |
1.51[827] |
1.28[828] |
-1.18[829] |
120 |
RPS6KB2 |
Ribosomal protein S6 kinase beta-2 |
[830] |
[831] |
[832] |
[833] |
[834] |
[835] |
[836] |
121 |
BAD |
Bcl2-associated agonist of cell death |
[837] |
-0.17[838] |
0.05[839] |
-1.00[840] |
0.66[841] |
1.07[842] |
-1.31[843] |
122 |
SHC1 |
SHC-transforming protein 1 |
[844] |
2.66[845] |
2.97[846] |
2.95[847] |
4.37[848] |
3.87[849] |
0.89[850] |
123 |
PSMB2 |
Proteasome subunit beta type-2 |
[851] |
2.50[852] |
2.23[853] |
2.54[854] |
2.95[855] |
2.97[856] |
1.17[857] |
124 |
AKT1S1 |
Proline-rich AKT1 substrate 1 |
[858] |
1.03[859] |
0.97[860] |
1.22[861] |
0.97[862] |
1.60[863] |
-1.08[864] |
125 |
NCSTN |
Nicastrin |
[865] |
2.85[866] |
2.09[867] |
2.15[868] |
2.81[869] |
2.70[870] |
0.51[871] |
126 |
RAF1 |
RAF proto-oncogene serine/threonine-protein kinase |
[872] |
1.43[873] |
1.93[874] |
3.10[875] |
1.54[876] |
2.41[877] |
1.21[878] |
127 |
DUSP6 |
Dual specificity protein phosphatase 6 |
[879] |
1.01[880] |
3.18[881] |
2.36[882] |
-2.19[883] |
1.61[884] |
0.37[885] |
128 |
SEL1L |
Protein sel-1 homolog 1 |
[886] |
1.82[887] |
2.35[888] |
2.17[889] |
2.69[890] |
2.39[891] |
2.94[892] |
129 |
FGFR4 |
Fibroblast growth factor receptor 4 |
[893] |
3.45[894] |
3.89[895] |
4.37[896] |
-2.51[897] |
-2.63[898] |
0.61[899] |
130 |
PSMB9 |
Proteasome subunit beta type-9 |
[900] |
-1.50[901] |
-4.13[902] |
-6.52[903] |
2.20[904] |
-0.03[905] |
-1.72[906] |
131 |
POLR2I |
DNA-directed RNA polymerase II subunit RPB9 |
[907] |
-0.09[908] |
0.13[909] |
-0.05[910] |
-0.55[911] |
-0.46[912] |
-0.91[913] |
132 |
DCTN1 |
Dynactin subunit 1 |
[914] |
3.36[915] |
2.61[916] |
1.86[917] |
3.15[918] |
3.17[919] |
0.67[920] |
133 |
KLC1 |
Kinesin light chain 1 |
[921] |
1.73[922] |
1.18[923] |
1.04[924] |
2.40[925] |
2.27[926] |
0.03[927] |
134 |
PSMD9 |
26S proteasome non-ATPase regulatory subunit 9 |
[928] |
0.88[929] |
1.36[930] |
0.30[931] |
0.83[932] |
1.30[933] |
-0.50[934] |
135 |
NRAS |
GTPase NRas |
[935] |
2.13[936] |
2.65[937] |
2.96[938] |
2.72[939] |
2.30[940] |
-0.14[941] |
136 |
CUL1 |
Cullin-1 |
[942] |
1.11[943] |
1.88[944] |
1.33[945] |
2.31[946] |
1.97[947] |
0.86[948] |
137 |
GTF2F1 |
General transcription factor IIF subunit 1 |
[949] |
1.89[950] |
1.57[951] |
2.94[952] |
1.33[953] |
1.85[954] |
-1.15[955] |
138 |
PPP2R5A |
Serine/threonine-protein phosphatase
2A 56 kDa regulatory subunit alpha isoform |
0.37[956] |
1.36[957] |
1.98[958] |
1.47[959] |
0.36[960] |
0.75[961] |
139 |
LMO7 |
LIM domain only protein 7 |
[962] |
1.60[963] |
2.73[964] |
2.21[965] |
0.10[966] |
0.81[967] |
0.64[968] |
140 |
PPP2R5C |
Serine/threonine-protein phosphatase
2A 56 kDa regulatory subunit gamma isoform |
1.19[969] |
2.16[970] |
1.76[971] |
2.66[972] |
2.48[973] |
-0.08[974] |
141 |
CDKN1B |
Cyclin-dependent kinase inhibitor 1B |
[975] |
1.41[976] |
1.95[977] |
2.04[978] |
0.61[979] |
1.09[980] |
-0.79[981] |
142 |
KIF5B |
Kinesin-1 heavy chain |
[982] |
1.91[983] |
3.98[984] |
3.64[985] |
4.57[986] |
3.66[987] |
1.44[988] |
143 |
PIK3AP1 |
Phosphoinositide 3-kinase adapter protein 1 |
[989] |
-1.29[990] |
1.17[991] |
1.69[992] |
-1.21[993] |
-6.03[994] |
2.61[995] |
144 |
MET |
Hepatocyte growth factor receptor |
[996] |
1.58[997] |
1.70[998] |
2.23[999] |
3.26[1000] |
1.99[1001] |
1.08[1002] |
145 |
GOLGA4 |
Golgin subfamily A member 4 |
[1003] |
0.50[1004] |
3.22[1005] |
3.58[1006] |
1.70[1007] |
1.97[1008] |
2.51[1009] |
146 |
HDAC3 |
Histone deacetylase 3 |
[1010] |
1.98[1011] |
2.12[1012] |
1.83[1013] |
1.67[1014] |
1.84[1015] |
-0.29[1016] |
147 |
ARAF |
Serine/threonine-protein kinase A-Raf |
[1017] |
1.04[1018] |
0.83[1019] |
1.00[1020] |
1.63[1021] |
1.67[1022] |
0.99[1023] |
148 |
PPP2R1B |
Serine/threonine-protein phosphatase
2A 65 kDa regulatory subunit A beta isoform |
1.95[1024] |
1.52[1025] |
1.83[1026] |
1.99[1027] |
1.79[1028] |
3.05[1029] |
149 |
TLN1 |
Talin-1 |
[1030] |
4.49[1031] |
3.21[1032] |
3.89[1033] |
4.83[1034] |
4.86[1035] |
3.47[1036] |
150 |
VCL |
Vinculin |
[1037] |
2.27[1038] |
2.08[1039] |
2.11[1040] |
4.55[1041] |
3.66[1042] |
0.92[1043] |
151 |
PAPSS1 |
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 |
[1044] |
2.22[1045] |
2.78[1046] |
1.95[1047] |
1.92[1048] |
2.01[1049] |
-1.38[1050] |
152 |
HRAS |
GTPase HRas |
[1051] |
0.49[1052] |
-0.12[1053] |
-1.02[1054] |
0.77[1055] |
0.57[1056] |
-2.55[1057] |
153 |
APBB1IP |
Amyloid beta A4 precursor
protein-binding family B member 1-interacting protein |
-7.04[1058] |
[1059] |
-5.12[1060] |
-1.57[1061] |
-4.33[1062] |
-0.42[1063] |
154 |
LRP5 |
Low-density lipoprotein receptor-related protein 5 |
[1064] |
3.61[1065] |
3.41[1066] |
3.94[1067] |
3.46[1068] |
2.01[1069] |
2.27[1070] |
155 |
POLR2B |
DNA-directed RNA polymerase II subunit RPB2 |
[1071] |
2.72[1072] |
3.19[1073] |
3.02[1074] |
2.83[1075] |
3.54[1076] |
1.07[1077] |
156 |
TGFBR2 |
TGF-beta receptor type-2 |
[1078] |
4.31[1079] |
3.87[1080] |
3.43[1081] |
2.79[1082] |
4.51[1083] |
1.62[1084] |
157 |
FIP1L1 |
Pre-mRNA 3'-end-processing factor FIP1 |
[1085] |
0.76[1086] |
1.16[1087] |
1.19[1088] |
1.79[1089] |
1.57[1090] |
-0.75[1091] |
158 |
MAP3K11 |
Mitogen-activated protein kinase kinase kinase 11 |
[1092] |
2.58[1093] |
2.62[1094] |
2.14[1095] |
1.87[1096] |
1.74[1097] |
0.57[1098] |
159 |
MAPK1 |
Mitogen-activated protein kinase 1 |
[1099] |
3.21[1100] |
3.44[1101] |
3.16[1102] |
3.57[1103] |
3.23[1104] |
1.89[1105] |
160 |
AKT2 |
RAC-beta serine/threonine-protein kinase |
[1106] |
2.46[1107] |
2.82[1108] |
2.85[1109] |
2.58[1110] |
2.38[1111] |
1.25[1112] |
161 |
CSK |
Tyrosine-protein kinase CSK |
[1113] |
1.87[1114] |
1.46[1115] |
1.73[1116] |
1.71[1117] |
1.31[1118] |
-0.75[1119] |
162 |
POLR2D |
DNA-directed RNA polymerase II subunit RPB4 |
[1120] |
1.75[1121] |
1.97[1122] |
1.17[1123] |
1.32[1124] |
1.55[1125] |
-0.32[1126] |
163 |
TRIM24 |
Transcription intermediary factor 1-alpha |
[1127] |
3.33[1128] |
2.54[1129] |
2.55[1130] |
0.02[1131] |
0.30[1132] |
0.00[1133] |
164 |
MLST8 |
Target of rapamycin complex subunit LST8 |
[1134] |
1.32[1135] |
1.74[1136] |
2.02[1137] |
0.75[1138] |
1.10[1139] |
-0.45[1140] |
165 |
KLB |
Beta-klotho |
[1141] |
2.09[1142] |
2.02[1143] |
3.37[1144] |
-4.24[1145] |
-4.87[1146] |
1.66[1147] |
166 |
PIM1 |
Serine/threonine-protein kinase pim-1 |
[1148] |
1.69[1149] |
1.55[1150] |
0.82[1151] |
2.11[1152] |
1.10[1153] |
-1.01[1154] |
167 |
PSMD10 |
26S proteasome non-ATPase regulatory subunit 10 |
[1155] |
1.44[1156] |
1.75[1157] |
1.69[1158] |
2.50[1159] |
1.85[1160] |
-0.51[1161] |
168 |
FGFR1OP2 |
FGFR1 oncogene partner 2 |
[1162] |
0.16[1163] |
1.37[1164] |
1.33[1165] |
0.37[1166] |
1.13[1167] |
-0.20[1168] |
169 |
GSK3A |
Glycogen synthase kinase-3 alpha |
[1169] |
2.12[1170] |
1.95[1171] |
1.95[1172] |
1.80[1173] |
2.57[1174] |
-1.72[1175] |
170 |
AGTRAP |
Type-1 angiotensin II receptor-associated protein |
[1176] |
1.66[1177] |
2.12[1178] |
0.92[1179] |
2.01[1180] |
2.06[1181] |
-1.41[1182] |
171 |
PTPN12 |
Tyrosine-protein phosphatase non-receptor type 12 |
[1183] |
2.28[1184] |
2.75[1185] |
1.62[1186] |
3.48[1187] |
2.57[1188] |
-0.34[1189] |
172 |
KRAS |
GTPase KRas |
[1190] |
0.98[1191] |
1.05[1192] |
2.55[1193] |
2.52[1194] |
2.19[1195] |
0.79[1196] |
173 |
MARK3 |
MAP/microtubule affinity-regulating kinase 3 |
[1197] |
1.42[1198] |
1.78[1199] |
1.66[1200] |
2.86[1201] |
2.55[1202] |
0.39[1203] |
174 |
ADAM10 |
Disintegrin and metalloproteinase domain-containing protein 10 |
[1204] |
2.48[1205] |
3.05[1206] |
2.98[1207] |
3.00[1208] |
3.42[1209] |
0.91[1210] |
175 |
DUSP9 |
Dual specificity protein phosphatase 9 |
[1211] |
4.95[1212] |
5.40[1213] |
3.78[1214] |
-3.29[1215] |
-3.44[1216] |
-4.16[1217] |
176 |
KANK1 |
KN motif and ankyrin repeat domain-containing protein 1 |
[1218] |
3.51[1219] |
3.74[1220] |
3.09[1221] |
0.87[1222] |
0.62[1223] |
2.74[1224] |
177 |
ERBB3 |
Receptor tyrosine-protein kinase erbB-3 |
[1225] |
3.50[1226] |
4.97[1227] |
3.92[1228] |
-4.15[1229] |
-3.89[1230] |
2.42[1231] |
178 |
ERLIN2 |
Erlin-2 |
[1232] |
2.29[1233] |
2.52[1234] |
3.39[1235] |
1.97[1236] |
1.90[1237] |
0.83[1238] |
179 |
PSME4 |
Proteasome activator complex subunit 4 |
[1239] |
2.96[1240] |
3.87[1241] |
3.79[1242] |
3.06[1243] |
3.05[1244] |
1.76[1245] |
180 |
POLR2A |
DNA-directed RNA polymerase II subunit RPB1 |
[1246] |
4.23[1247] |
2.86[1248] |
3.75[1249] |
3.88[1250] |
4.28[1251] |
1.91[1252] |
181 |
PPP2R5D |
Serine/threonine-protein phosphatase
2A 56 kDa regulatory subunit delta isoform |
2.75[1253] |
2.60[1254] |
2.06[1255] |
3.01[1256] |
2.91[1257] |
-0.15[1258] |
182 |
DUSP16 |
Dual specificity protein phosphatase 16 |
[1259] |
3.06[1260] |
3.17[1261] |
2.81[1262] |
0.32[1263] |
1.23[1264] |
1.56[1265] |
183 |
ARRB2 |
Beta-arrestin-2 |
[1266] |
1.66[1267] |
2.14[1268] |
2.00[1269] |
0.41[1270] |
1.22[1271] |
-0.76[1272] |
184 |
FGFR3 |
Fibroblast growth factor receptor 3 |
[1273] |
4.22[1274] |
4.23[1275] |
4.46[1276] |
-1.57[1277] |
-0.21[1278] |
0.56[1279] |
185 |
RHOG |
Rho-related GTP-binding protein RhoG |
[1280] |
1.77[1281] |
0.67[1282] |
0.51[1283] |
1.75[1284] |
1.33[1285] |
-0.59[1286] |
186 |
PIK3R1 |
Phosphatidylinositol 3-kinase regulatory subunit alpha |
[1287] |
1.02[1288] |
1.23[1289] |
2.23[1290] |
3.79[1291] |
3.30[1292] |
3.12[1293] |
187 |
DUSP10 |
Dual specificity protein phosphatase 10 |
[1294] |
-1.50[1295] |
-2.16[1296] |
-0.81[1297] |
0.93[1298] |
-0.05[1299] |
0.12[1300] |
188 |
PRR5 |
Proline-rich protein 5 |
[1301] |
0.91[1302] |
1.06[1303] |
0.04[1304] |
-0.56[1305] |
-3.35[1306] |
-0.66[1307] |
189 |
SHOC2 |
Leucine-rich repeat protein SHOC-2 |
[1308] |
0.74[1309] |
2.20[1310] |
1.70[1311] |
1.85[1312] |
2.14[1313] |
0.81[1314] |
190 |
AP3B1 |
AP-3 complex subunit beta-1 |
[1315] |
2.24[1316] |
2.91[1317] |
2.72[1318] |
2.93[1319] |
2.81[1320] |
0.72[1321] |
191 |
EML4 |
Echinoderm microtubule-associated protein-like 4 |
[1322] |
4.59[1323] |
5.78[1324] |
4.22[1325] |
3.82[1326] |
2.31[1327] |
2.24[1328] |
192 |
FXR1 |
Fragile X mental retardation syndrome-related protein 1 |
[1329] |
2.83[1330] |
4.11[1331] |
4.43[1332] |
3.57[1333] |
3.84[1334] |
0.93[1335] |
193 |
HES1 |
Transcription factor HES-1 |
[1336] |
1.06[1337] |
-1.34[1338] |
0.81[1339] |
0.45[1340] |
-0.37[1341] |
-1.28[1342] |
194 |
NCOR1 |
Nuclear receptor corepressor 1 |
[1343] |
2.58[1344] |
3.17[1345] |
3.72[1346] |
3.29[1347] |
3.34[1348] |
2.91[1349] |
195 |
MYO18A |
Unconventional myosin-XVIIIa |
[1350] |
2.57[1351] |
2.95[1352] |
3.75[1353] |
2.75[1354] |
1.78[1355] |
2.73[1356] |
196 |
SOS1 |
Son of sevenless homolog 1 |
[1357] |
1.40[1358] |
3.02[1359] |
2.43[1360] |
2.57[1361] |
1.81[1362] |
0.65[1363] |
197 |
HDAC2 |
Histone deacetylase 2 |
[1364] |
3.22[1365] |
4.64[1366] |
3.91[1367] |
3.88[1368] |
4.03[1369] |
0.31[1370] |
198 |
PSEN1 |
Presenilin-1 |
[1371] |
2.55[1372] |
2.86[1373] |
2.33[1374] |
2.98[1375] |
2.86[1376] |
1.11[1377] |
199 |
HDAC6 |
Histone deacetylase 6 |
[1378] |
2.15[1379] |
3.19[1380] |
3.18[1381] |
2.00[1382] |
1.49[1383] |
2.27[1384] |
200 |
HDAC8 |
Histone deacetylase 8 |
[1385] |
0.52[1386] |
0.41[1387] |
0.59[1388] |
0.95[1389] |
1.19[1390] |
-0.24[1391] |
201 |
PTEN |
Phosphatidylinositol
3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN |
0.96[1392] |
2.44[1393] |
2.54[1394] |
1.16[1395] |
2.42[1396] |
2.59[1397] |
202 |
ERBB2 |
Receptor tyrosine-protein kinase erbB-2 |
[1398] |
3.87[1399] |
2.78[1400] |
3.85[1401] |
2.98[1402] |
2.59[1403] |
0.27[1404] |
203 |
MDM2 |
E3 ubiquitin-protein ligase Mdm2 |
[1405] |
3.61[1406] |
5.12[1407] |
2.26[1408] |
2.23[1409] |
3.12[1410] |
2.28[1411] |
204 |
RANBP2 |
E3 SUMO-protein ligase RanBP2 |
[1412] |
1.97[1413] |
3.75[1414] |
3.39[1415] |
3.26[1416] |
3.42[1417] |
3.06[1418] |
205 |
PSMD5 |
26S proteasome non-ATPase regulatory subunit 5 |
[1419] |
1.86[1420] |
1.40[1421] |
2.88[1422] |
2.89[1423] |
3.00[1424] |
0.94[1425] |
206 |
CAMK2D |
Calcium/calmodulin-dependent protein kinase type II subunit delta |
[1426] |
1.63[1427] |
2.03[1428] |
3.45[1429] |
2.40[1430] |
1.60[1431] |
1.53[1432] |
207 |
FZD5 |
Frizzled-5 |
[1433] |
2.47[1434] |
3.43[1435] |
4.32[1436] |
0.59[1437] |
-0.71[1438] |
2.70[1439] |
208 |
SMAD3 |
Mothers against decapentaplegic homolog 3 |
[1440] |
3.43[1441] |
2.91[1442] |
3.04[1443] |
3.52[1444] |
4.41[1445] |
0.33[1446] |
209 |
ZC3HAV1 |
Zinc finger CCCH-type antiviral protein 1 |
[1447] |
1.95[1448] |
1.67[1449] |
2.29[1450] |
3.25[1451] |
2.66[1452] |
2.01[1453] |
210 |
CUX1 |
Homeobox protein cut-like 1 |
[1454] |
3.03[1455] |
2.26[1456] |
2.79[1457] |
3.35[1458] |
3.77[1459] |
1.60[1460] |
211 |
BCL2A1 |
Bcl-2-related protein A1 |
[1461] |
-3.27[1462] |
-5.01[1463] |
-9.51[1464] |
-7.54[1465] |
-3.99[1466] |
-4.78[1467] |
212 |
PPP2R5E |
Serine/threonine-protein phosphatase
2A 56 kDa regulatory subunit epsilon isoform |
1.61[1468] |
1.88[1469] |
1.31[1470] |
2.58[1471] |
2.38[1472] |
0.31[1473] |
213 |
EGFR |
Epidermal growth factor receptor |
[1474] |
0.80[1475] |
0.52[1476] |
3.30[1477] |
2.16[1478] |
2.78[1479] |
2.77[1480] |
214 |
ZC3HC1 |
Nuclear-interacting partner of ALK |
[1481] |
1.61[1482] |
1.52[1483] |
1.86[1484] |
2.22[1485] |
1.75[1486] |
-0.26[1487] |
215 |
TPR |
Nucleoprotein TPR |
[1488] |
2.13[1489] |
4.09[1490] |
4.30[1491] |
4.27[1492] |
4.50[1493] |
2.71[1494] |
216 |
LYN |
Tyrosine-protein kinase Lyn |
[1495] |
0.64[1496] |
0.55[1497] |
0.98[1498] |
2.78[1499] |
1.55[1500] |
0.13[1501] |
217 |
PIK3R2 |
Phosphatidylinositol 3-kinase regulatory subunit beta |
[1502] |
3.37[1503] |
3.69[1504] |
4.20[1505] |
2.43[1506] |
3.00[1507] |
-0.18[1508] |
218 |
AREG |
Amphiregulin |
[1509] |
-1.36[1510] |
-4.51[1511] |
-6.37[1512] |
-7.97[1513] |
2.34[1514] |
-10.19[1515] |
219 |
AGGF1 |
Angiogenic factor with G patch and FHA domains 1 |
[1516] |
0.98[1517] |
2.14[1518] |
2.23[1519] |
2.48[1520] |
2.22[1521] |
1.34[1522] |
220 |
NCBP1 |
Nuclear cap-binding protein subunit 1 |
[1523] |
2.75[1524] |
3.06[1525] |
2.78[1526] |
3.48[1527] |
4.03[1528] |
1.35[1529] |
221 |
CPSF6 |
Cleavage and polyadenylation specificity factor subunit 6 |
[1530] |
2.95[1531] |
3.68[1532] |
3.77[1533] |
3.62[1534] |
3.44[1535] |
1.90[1536] |
222 |
CDK8 |
Cyclin-dependent kinase 8 |
[1537] |
0.65[1538] |
1.29[1539] |
0.26[1540] |
1.22[1541] |
0.84[1542] |
-1.64[1543] |
223 |
ADAM17 |
Disintegrin and metalloproteinase domain-containing protein 17 |
[1544] |
2.17[1545] |
2.15[1546] |
1.79[1547] |
3.46[1548] |
2.61[1549] |
0.19[1550] |
224 |
KAT2A |
Histone acetyltransferase KAT2A |
[1551] |
3.53[1552] |
3.48[1553] |
2.49[1554] |
2.85[1555] |
2.71[1556] |
0.40[1557] |
225 |
AXIN1 |
Axin-1 |
[1558] |
2.85[1559] |
3.26[1560] |
1.60[1561] |
-6.97[1562] |
1.88[1563] |
-0.54[1564] |
226 |
IQGAP1 |
Ras GTPase-activating-like protein IQGAP1 |
[1565] |
3.35[1566] |
2.99[1567] |
3.30[1568] |
5.69[1569] |
5.54[1570] |
2.14[1571] |
227 |
TGFBR1 |
TGF-beta receptor type-1 |
[1572] |
1.83[1573] |
2.14[1574] |
1.55[1575] |
2.07[1576] |
3.18[1577] |
1.45[1578] |
228 |
MECP2 |
Methyl-CpG-binding protein 2 |
[1579] |
2.22[1580] |
2.60[1581] |
2.71[1582] |
3.31[1583] |
3.42[1584] |
0.94[1585] |
229 |
TBL1XR1 |
F-box-like/WD repeat-containing protein TBL1XR1 |
[1586] |
2.58[1587] |
3.21[1588] |
3.75[1589] |
4.13[1590] |
3.70[1591] |
2.99[1592] |
230 |
QKI |
Protein quaking |
[1593] |
3.58[1594] |
3.98[1595] |
3.73[1596] |
4.00[1597] |
4.24[1598] |
2.81[1599] |
231 |
PSEN2 |
Presenilin-2 |
[1600] |
0.81[1601] |
0.04[1602] |
-3.87[1603] |
1.80[1604] |
0.44[1605] |
0.02[1606] |
232 |
TBL1X |
F-box-like/WD repeat-containing protein TBL1X |
[1607] |
2.84[1608] |
3.33[1609] |
4.79[1610] |
-2.68[1611] |
2.82[1612] |
1.86[1613] |
233 |
MAPK3 |
Mitogen-activated protein kinase 3 |
[1614] |
3.35[1615] |
3.48[1616] |
3.43[1617] |
2.15[1618] |
2.18[1619] |
-0.93[1620] |
234 |
GSK3B |
Glycogen synthase kinase-3 beta |
[1621] |
2.76[1622] |
2.49[1623] |
2.96[1624] |
3.54[1625] |
3.37[1626] |
1.28[1627] |
235 |
FAM114A2 |
Protein FAM114A2 |
[1628] |
1.13[1629] |
1.26[1630] |
1.31[1631] |
2.01[1632] |
1.83[1633] |
0.63[1634] |
236 |
FGF2 |
Fibroblast growth factor 2 |
[1635] |
-5.19[1636] |
-4.84[1637] |
-0.79[1638] |
2.66[1639] |
4.25[1640] |
-1.55[1641] |
237 |
STAT5B |
Signal transducer and activator of transcription 5B |
[1642] |
2.85[1643] |
2.57[1644] |
3.17[1645] |
3.27[1646] |
2.42[1647] |
1.74[1648] |
238 |
MPRIP |
Myosin phosphatase Rho-interacting protein |
[1649] |
3.68[1650] |
3.55[1651] |
3.83[1652] |
5.24[1653] |
5.47[1654] |
2.33[1655] |
239 |
CHUK |
Inhibitor of nuclear factor kappa-B kinase subunit alpha |
[1656] |
2.40[1657] |
3.71[1658] |
3.57[1659] |
2.37[1660] |
3.19[1661] |
1.63[1662] |
240 |
GOLGB1 |
Golgin subfamily B member 1 |
[1663] |
2.08[1664] |
4.37[1665] |
4.52[1666] |
3.71[1667] |
3.85[1668] |
4.12[1669] |
241 |
RNF43 |
E3 ubiquitin-protein ligase RNF43 |
[1670] |
4.58[1671] |
3.78[1672] |
2.67[1673] |
0.19[1674] |
1.37[1675] |
0.27[1676] |
242 |
WDR48 |
WD repeat-containing protein 48 |
[1677] |
2.54[1678] |
3.50[1679] |
3.59[1680] |
2.22[1681] |
2.82[1682] |
1.34[1683] |
243 |
RAC2 |
Ras-related C3 botulinum toxin substrate 2 |
[1684] |
-0.21[1685] |
-6.11[1686] |
-6.82[1687] |
0.33[1688] |
4.15[1689] |
-1.12[1690] |
244 |
BCR |
Breakpoint cluster region protein |
[1691] |
3.72[1692] |
3.06[1693] |
3.22[1694] |
2.74[1695] |
3.13[1696] |
1.81[1697] |
245 |
SRC |
Proto-oncogene tyrosine-protein kinase Src |
[1698] |
4.52[1699] |
4.60[1700] |
3.50[1701] |
4.12[1702] |
3.31[1703] |
-0.74[1704] |
246 |
MIB2 |
E3 ubiquitin-protein ligase MIB2 |
[1705] |
2.61[1706] |
3.15[1707] |
2.42[1708] |
2.09[1709] |
2.40[1710] |
0.23[1711] |
247 |
PDPK1 |
3-phosphoinositide-dependent protein kinase 1 |
[1712] |
3.83[1713] |
5.11[1714] |
3.72[1715] |
3.16[1716] |
3.56[1717] |
2.62[1718] |
248 |
PLCG1 |
1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase gamma-1 |
4.99[1719] |
4.70[1720] |
3.93[1721] |
4.54[1722] |
4.05[1723] |
0.46[1724] |
249 |
RBPJ |
Recombining binding protein suppressor of hairless |
[1725] |
2.84[1726] |
3.50[1727] |
4.41[1728] |
3.74[1729] |
3.68[1730] |
1.97[1731] |
250 |
FBXW7 |
F-box/WD repeat-containing protein 7 |
[1732] |
0.76[1733] |
1.53[1734] |
1.41[1735] |
0.82[1736] |
1.85[1737] |
1.26[1738] |
251 |
TNKS2 |
Tankyrase-2 |
[1739] |
3.21[1740] |
4.38[1741] |
4.74[1742] |
3.85[1743] |
4.04[1744] |
2.53[1745] |
252 |
MTOR |
Serine/threonine-protein kinase mTOR |
[1746] |
4.03[1747] |
5.14[1748] |
4.60[1749] |
4.41[1750] |
4.49[1751] |
3.56[1752] |
253 |
BAG4 |
BAG family molecular chaperone regulator 4 |
[1753] |
1.85[1754] |
2.90[1755] |
4.09[1756] |
1.66[1757] |
1.89[1758] |
1.93[1759] |
254 |
EIF2AK3 |
Eukaryotic translation initiation factor 2-alpha kinase 3 |
[1760] |
2.04[1761] |
2.95[1762] |
3.02[1763] |
1.91[1764] |
2.45[1765] |
1.87[1766] |
255 |
MRAS |
Ras-related protein M-Ras |
[1767] |
3.25[1768] |
-2.33[1769] |
-1.26[1770] |
2.18[1771] |
2.50[1772] |
-1.55[1773] |
256 |
BRAP |
BRCA1-associated protein |
[1774] |
1.85[1775] |
2.15[1776] |
2.13[1777] |
2.60[1778] |
2.73[1779] |
0.86[1780] |
257 |
TSC2 |
Tuberin |
[1781] |
3.31[1782] |
2.93[1783] |
3.52[1784] |
2.92[1785] |
3.46[1786] |
2.20[1787] |
258 |
PIK3CB |
Phosphatidylinositol
4,5-bisphosphate 3-kinase catalytic subunit beta isoform |
2.71[1788] |
3.31[1789] |
3.37[1790] |
2.77[1791] |
2.94[1792] |
1.27[1793] |
259 |
SMAD4 |
Mothers against decapentaplegic homolog 4 |
[1794] |
2.89[1795] |
3.61[1796] |
3.48[1797] |
3.63[1798] |
4.01[1799] |
2.91[1800] |
260 |
PPFIBP1 |
Liprin-beta-1 |
[1801] |
2.64[1802] |
2.62[1803] |
3.32[1804] |
4.17[1805] |
4.14[1806] |
2.52[1807] |
261 |
AGK |
Acylglycerol kinase, mitochondrial |
[1808] |
2.73[1809] |
2.90[1810] |
2.48[1811] |
2.68[1812] |
2.67[1813] |
0.82[1814] |
262 |
HDAC10 |
Histone deacetylase 10 |
[1815] |
1.60[1816] |
2.27[1817] |
2.97[1818] |
1.44[1819] |
1.09[1820] |
0.29[1821] |
263 |
IRS1 |
Insulin receptor substrate 1 |
[1822] |
3.59[1823] |
3.12[1824] |
4.45[1825] |
3.43[1826] |
3.02[1827] |
2.23[1828] |
264 |
MIB1 |
E3 ubiquitin-protein ligase MIB1 |
[1829] |
2.99[1830] |
4.30[1831] |
4.42[1832] |
4.64[1833] |
3.70[1834] |
2.81[1835] |
265 |
KAT2B |
Histone acetyltransferase KAT2B |
[1836] |
-0.55[1837] |
-1.58[1838] |
0.69[1839] |
1.66[1840] |
2.09[1841] |
1.90[1842] |
266 |
CAMK2G |
Calcium/calmodulin-dependent protein
kinase type II subunit gamma |
2.27[1843] |
3.58[1844] |
3.09[1845] |
3.41[1846] |
2.98[1847] |
1.07[1848] |
267 |
TRAK1 |
Trafficking kinesin-binding protein 1 |
[1849] |
3.83[1850] |
3.59[1851] |
3.37[1852] |
3.13[1853] |
3.07[1854] |
1.57[1855] |
268 |
RNF213 |
E3 ubiquitin-protein ligase RNF213 |
[1856] |
5.50[1857] |
3.89[1858] |
5.61[1859] |
6.07[1860] |
5.17[1861] |
5.20[1862] |
269 |
GCC2 |
GRIP and coiled-coil domain-containing protein 2 |
[1863] |
1.61[1864] |
4.14[1865] |
3.27[1866] |
2.83[1867] |
2.99[1868] |
2.57[1869] |
270 |
FOXO3 |
Forkhead box protein O3 |
[1870] |
1.95[1871] |
2.13[1872] |
2.67[1873] |
2.12[1874] |
3.37[1875] |
2.45[1876] |
271 |
TRIP11 |
Thyroid receptor-interacting protein 11 |
[1877] |
0.97[1878] |
3.37[1879] |
3.04[1880] |
3.62[1881] |
3.16[1882] |
3.21[1883] |
272 |
SPRED2 |
Sprouty-related, EVH1 domain-containing protein 2 |
[1884] |
3.58[1885] |
3.92[1886] |
3.59[1887] |
2.87[1888] |
3.28[1889] |
1.03[1890] |
273 |
FZD4 |
Frizzled-4 |
[1891] |
5.58[1892] |
4.62[1893] |
3.55[1894] |
2.42[1895] |
1.76[1896] |
3.06[1897] |
274 |
JAG1 |
Protein jagged-1 |
[1898] |
6.27[1899] |
4.95[1900] |
4.32[1901] |
3.24[1902] |
1.89[1903] |
1.16[1904] |
275 |
CASP9 |
Caspase-9 |
[1905] |
1.65[1906] |
2.70[1907] |
1.73[1908] |
1.97[1909] |
1.29[1910] |
-0.42[1911] |
276 |
NCOR2 |
Nuclear receptor corepressor 2 |
[1912] |
4.84[1913] |
3.33[1914] |
3.33[1915] |
5.87[1916] |
5.38[1917] |
2.00[1918] |
277 |
SMAD2 |
Mothers against decapentaplegic homolog 2 |
[1919] |
3.52[1920] |
3.87[1921] |
3.27[1922] |
4.11[1923] |
4.30[1924] |
2.68[1925] |
278 |
EP300 |
Histone acetyltransferase p300 |
[1926] |
4.22[1927] |
3.90[1928] |
4.70[1929] |
4.29[1930] |
4.35[1931] |
2.87[1932] |
279 |
HDAC5 |
Histone deacetylase 5 |
[1933] |
4.18[1934] |
5.10[1935] |
4.36[1936] |
3.38[1937] |
2.78[1938] |
1.31[1939] |
280 |
STAT5A |
Signal transducer and activator of transcription 5A |
[1940] |
-0.45[1941] |
0.82[1942] |
-0.22[1943] |
0.88[1944] |
1.64[1945] |
0.35[1946] |
281 |
TCF7L2 |
Transcription factor 7-like 2 |
[1947] |
2.36[1948] |
3.22[1949] |
3.32[1950] |
2.42[1951] |
2.41[1952] |
1.84[1953] |
282 |
TGFB1 |
Transforming growth factor beta-1 |
[1954] |
4.97[1955] |
4.02[1956] |
1.18[1957] |
5.56[1958] |
4.80[1959] |
-1.11[1960] |
283 |
MAML1 |
Mastermind-like protein 1 |
[1961] |
3.61[1962] |
3.67[1963] |
4.11[1964] |
3.97[1965] |
4.11[1966] |
1.20[1967] |
284 |
AKAP9 |
A-kinase anchor protein 9 |
[1968] |
1.52[1969] |
4.32[1970] |
4.41[1971] |
3.52[1972] |
3.65[1973] |
5.19[1974] |
285 |
ZMYM2 |
Zinc finger MYM-type protein 2 |
[1975] |
3.13[1976] |
4.35[1977] |
3.77[1978] |
4.69[1979] |
4.23[1980] |
3.39[1981] |
286 |
IRS2 |
Insulin receptor substrate 2 |
[1982] |
-4.15[1983] |
[1984] |
-1.31[1985] |
1.06[1986] |
4.89[1987] |
2.50[1988] |
287 |
PPP2R5B |
Serine/threonine-protein phosphatase
2A 56 kDa regulatory subunit beta isoform |
2.27[1989] |
2.13[1990] |
1.39[1991] |
2.01[1992] |
3.19[1993] |
0.21[1994] |
288 |
FYN |
Tyrosine-protein kinase Fyn |
[1995] |
2.44[1996] |
-6.07[1997] |
2.40[1998] |
3.19[1999] |
4.73[2000] |
1.08[2001] |
289 |
KREMEN1 |
Kremen protein 1 |
[2002] |
4.52[2003] |
3.40[2004] |
3.38[2005] |
3.29[2006] |
3.08[2007] |
0.46[2008] |
290 |
DKK1 |
Dickkopf-related protein 1 |
[2009] |
6.78[2010] |
3.22[2011] |
3.58[2012] |
3.06[2013] |
5.83[2014] |
-5.32[2015] |
291 |
TGFA |
Protransforming growth factor alpha |
[2016] |
3.29[2017] |
4.44[2018] |
-6.70[2019] |
0.76[2020] |
-0.45[2021] |
-0.28[2022] |
292 |
ATG7 |
Ubiquitin-like modifier-activating enzyme ATG7 |
[2023] |
2.49[2024] |
2.09[2025] |
2.73[2026] |
2.40[2027] |
3.27[2028] |
1.87[2029] |
293 |
BIRC6 |
Baculoviral IAP repeat-containing protein 6 |
[2030] |
4.45[2031] |
5.41[2032] |
5.25[2033] |
5.71[2034] |
5.06[2035] |
5.67[2036] |
294 |
ZFYVE9 |
Zinc finger FYVE domain-containing protein 9 |
[2037] |
3.14[2038] |
3.47[2039] |
3.32[2040] |
3.33[2041] |
3.79[2042] |
2.32[2043] |
295 |
LRP6 |
Low-density lipoprotein receptor-related protein 6 |
[2044] |
3.32[2045] |
4.08[2046] |
5.33[2047] |
3.58[2048] |
4.14[2049] |
4.90[2050] |
296 |
CLCN6 |
Chloride transport protein 6 |
[2051] |
2.20[2052] |
4.86[2053] |
3.20[2054] |
3.13[2055] |
1.94[2056] |
1.53[2057] |
297 |
PIK3CA |
Phosphatidylinositol
4,5-bisphosphate 3-kinase catalytic subunit alpha isoform |
1.12[2058] |
2.85[2059] |
2.94[2060] |
2.85[2061] |
3.06[2062] |
2.03[2063] |
298 |
PIK3CD |
Phosphatidylinositol
4,5-bisphosphate 3-kinase catalytic subunit delta isoform |
3.38[2064] |
4.56[2065] |
0.65[2066] |
2.00[2067] |
2.78[2068] |
0.41[2069] |
299 |
HIP1 |
Huntingtin-interacting protein 1 |
[2070] |
3.07[2071] |
3.24[2072] |
3.86[2073] |
4.72[2074] |
4.10[2075] |
2.68[2076] |
300 |
HBEGF |
Proheparin-binding EGF-like growth factor |
[2077] |
0.51[2078] |
-0.21[2079] |
-1.38[2080] |
2.03[2081] |
1.72[2082] |
-2.32[2083] |
301 |
CREB1 |
Cyclic AMP-responsive element-binding protein 1 |
[2084] |
3.22[2085] |
4.47[2086] |
4.86[2087] |
4.26[2088] |
4.22[2089] |
2.46[2090] |
302 |
CREBBP |
CREB-binding protein |
[2091] |
4.40[2092] |
3.70[2093] |
4.21[2094] |
4.48[2095] |
4.50[2096] |
3.35[2097] |
303 |
FOXO1 |
Forkhead box protein O1 |
[2098] |
3.19[2099] |
2.95[2100] |
2.99[2101] |
2.90[2102] |
4.92[2103] |
3.20[2104] |
304 |
NF1 |
Neurofibromin |
[2105] |
3.96[2106] |
4.38[2107] |
5.10[2108] |
5.69[2109] |
5.14[2110] |
4.22[2111] |
305 |
FLT3LG |
Fms-related tyrosine kinase 3 ligand |
[2112] |
-0.76[2113] |
-0.57[2114] |
-0.21[2115] |
-0.61[2116] |
0.48[2117] |
-2.04[2118] |
306 |
PDGFA |
Platelet-derived growth factor subunit A |
[2119] |
0.49[2120] |
0.80[2121] |
2.78[2122] |
1.38[2123] |
0.48[2124] |
-0.64[2125] |
307 |
RICTOR |
Rapamycin-insensitive companion of mTOR |
[2126] |
2.22[2127] |
4.40[2128] |
4.97[2129] |
4.08[2130] |
4.29[2131] |
3.63[2132] |
308 |
DUSP8 |
Dual specificity protein phosphatase 8 |
[2133] |
2.64[2134] |
2.17[2135] |
1.25[2136] |
0.30[2137] |
0.88[2138] |
-3.71[2139] |
309 |
GAB2 |
GRB2-associated-binding protein 2 |
[2140] |
3.06[2141] |
2.94[2142] |
3.09[2143] |
2.65[2144] |
2.74[2145] |
0.66[2146] |
310 |
BCL2L11 |
Bcl-2-like protein 11 |
[2147] |
3.00[2148] |
3.10[2149] |
3.33[2150] |
3.59[2151] |
2.57[2152] |
2.10[2153] |
311 |
FOXO4 |
Forkhead box protein O4 |
[2154] |
2.23[2155] |
2.72[2156] |
2.45[2157] |
1.89[2158] |
2.11[2159] |
-0.58[2160] |
312 |
ESR1 |
Estrogen receptor |
[2161] |
-5.81[2162] |
[2163] |
-4.30[2164] |
-2.45[2165] |
-4.70[2166] |
2.51[2167] |
313 |
HDAC7 |
Histone deacetylase 7 |
[2168] |
3.88[2169] |
3.33[2170] |
2.92[2171] |
4.82[2172] |
5.15[2173] |
1.09[2174] |
314 |
TNKS |
Tankyrase-1 |
[2175] |
4.23[2176] |
4.65[2177] |
5.52[2178] |
3.33[2179] |
4.37[2180] |
3.32[2181] |
315 |
FGFR2 |
Fibroblast growth factor receptor 2 |
[2182] |
-1.01[2183] |
0.29[2184] |
4.13[2185] |
3.18[2186] |
-1.65[2187] |
3.54[2188] |
316 |
FZD6 |
Frizzled-6 |
[2189] |
3.28[2190] |
4.20[2191] |
1.59[2192] |
6.46[2193] |
5.23[2194] |
1.23[2195] |
317 |
ETV6 |
Transcription factor ETV6 |
[2196] |
1.83[2197] |
1.97[2198] |
2.01[2199] |
3.39[2200] |
2.99[2201] |
1.71[2202] |
318 |
HDAC11 |
Histone deacetylase 11 |
[2203] |
4.06[2204] |
4.81[2205] |
3.55[2206] |
3.10[2207] |
2.51[2208] |
-0.11[2209] |
319 |
DUSP7 |
Dual specificity protein phosphatase 7 |
[2210] |
3.05[2211] |
2.23[2212] |
3.38[2213] |
1.30[2214] |
3.69[2215] |
0.14[2216] |
320 |
CTBP2 |
C-terminal-binding protein 2 |
[2217] |
-0.57[2218] |
-0.04[2219] |
3.59[2220] |
5.00[2221] |
5.30[2222] |
1.66[2223] |
321 |
NRG1 |
Pro-neuregulin-1, membrane-bound isoform |
[2224] |
1.83[2225] |
-4.21[2226] |
-1.42[2227] |
3.77[2228] |
-3.69[2229] |
0.88[2230] |
322 |
SHH |
Sonic hedgehog protein |
[2231] |
1.88[2232] |
1.82[2233] |
1.80[2234] |
-5.46[2235] |
-5.59[2236] |
0.24[2237] |
323 |
FRS2 |
Fibroblast growth factor receptor substrate 2 |
[2238] |
2.78[2239] |
3.97[2240] |
4.37[2241] |
4.63[2242] |
4.26[2243] |
3.46[2244] |
324 |
APC |
Adenomatous polyposis coli protein |
[2245] |
2.07[2246] |
3.83[2247] |
3.57[2248] |
3.95[2249] |
4.59[2250] |
3.85[2251] |
325 |
STRN |
Striatin |
[2252] |
3.46[2253] |
4.52[2254] |
4.04[2255] |
5.05[2256] |
4.95[2257] |
3.01[2258] |
326 |
ITGB3 |
Integrin beta-3 |
[2259] |
-0.14[2260] |
-2.75[2261] |
0.67[2262] |
4.57[2263] |
4.25[2264] |
1.44[2265] |
327 |
BRAF |
Serine/threonine-protein kinase B-raf |
[2266] |
1.74[2267] |
1.57[2268] |
3.50[2269] |
2.46[2270] |
2.17[2271] |
1.97[2272] |
328 |
NR4A1 |
Nuclear receptor subfamily 4 group A member 1 |
[2273] |
2.71[2274] |
3.35[2275] |
3.39[2276] |
1.87[2277] |
2.97[2278] |
0.64[2279] |
329 |
FZD8 |
Frizzled-8 |
[2280] |
-1.63[2281] |
-6.87[2282] |
0.40[2283] |
-1.24[2284] |
-0.02[2285] |
-0.08[2286] |
330 |
BTC |
Probetacellulin |
[2287] |
-6.64[2288] |
-6.94[2289] |
-2.82[2290] |
-1.15[2291] |
-1.17[2292] |
-2.80[2293] |
331 |
HHAT |
Protein-cysteine N-palmitoyltransferase HHAT |
[2294] |
2.53[2295] |
1.30[2296] |
-0.42[2297] |
3.11[2298] |
0.39[2299] |
0.52[2300] |
332 |
FRS3 |
Fibroblast growth factor receptor substrate 3 |
[2301] |
2.12[2302] |
2.05[2303] |
0.93[2304] |
2.02[2305] |
1.68[2306] |
-0.79[2307] |
333 |
MAMLD1 |
Mastermind-like domain-containing protein 1 |
[2308] |
-0.40[2309] |
-6.81[2310] |
-0.65[2311] |
2.78[2312] |
2.61[2313] |
-0.22[2314] |
334 |
FGFR1 |
Fibroblast growth factor receptor 1 |
[2315] |
6.07[2316] |
4.48[2317] |
6.03[2318] |
6.78[2319] |
6.06[2320] |
1.78[2321] |
335 |
GAB1 |
GRB2-associated-binding protein 1 |
[2322] |
2.80[2323] |
3.98[2324] |
4.00[2325] |
3.66[2326] |
3.53[2327] |
2.99[2328] |
336 |
HEY1 |
Hairy/enhancer-of-split related with YRPW motif protein 1 |
[2329] |
3.14[2330] |
1.68[2331] |
1.66[2332] |
1.23[2333] |
0.04[2334] |
0.17[2335] |
337 |
JAK2 |
Tyrosine-protein kinase JAK2 |
[2336] |
1.72[2337] |
1.81[2338] |
1.27[2339] |
2.49[2340] |
3.09[2341] |
2.82[2342] |
338 |
APH1B |
Gamma-secretase subunit APH-1B |
[2343] |
1.26[2344] |
2.16[2345] |
5.19[2346] |
4.82[2347] |
3.87[2348] |
1.34[2349] |
339 |
PDGFB |
Platelet-derived growth factor subunit B |
[2350] |
4.55[2351] |
4.51[2352] |
1.60[2353] |
1.79[2354] |
1.37[2355] |
0.49[2356] |
340 |
SPRED1 |
Sprouty-related, EVH1 domain-containing protein 1 |
[2357] |
3.91[2358] |
4.51[2359] |
4.33[2360] |
5.70[2361] |
6.20[2362] |
2.90[2363] |
341 |
NOTCH1 |
Neurogenic locus notch homolog protein 1 |
[2364] |
3.40[2365] |
2.33[2366] |
3.57[2367] |
4.31[2368] |
4.67[2369] |
4.75[2370] |
342 |
ARRB1 |
Beta-arrestin-1 |
[2371] |
5.08[2372] |
4.98[2373] |
4.17[2374] |
3.87[2375] |
3.69[2376] |
3.39[2377] |
343 |
CAMK2B |
Calcium/calmodulin-dependent protein kinase type II subunit beta |
[2378] |
-1.04[2379] |
-2.27[2380] |
-5.33[2381] |
-1.14[2382] |
-0.49[2383] |
1.26[2384] |
344 |
NRG4 |
Pro-neuregulin-4, membrane-bound isoform |
[2385] |
-2.60[2386] |
0.37[2387] |
0.22[2388] |
2.01[2389] |
-0.18[2390] |
-0.82[2391] |
345 |
CNTRL |
Centriolin |
[2392] |
2.50[2393] |
4.84[2394] |
5.58[2395] |
4.48[2396] |
4.19[2397] |
2.69[2398] |
346 |
BIN2 |
Bridging integrator 2 |
[2399] |
-4.69[2400] |
-4.37[2401] |
-7.59[2402] |
-4.56[2403] |
-6.01[2404] |
1.54[2405] |
347 |
FGF7 |
Fibroblast growth factor 7 |
[2406] |
-7.80[2407] |
-4.01[2408] |
[2409] |
-3.65[2410] |
0.63[2411] |
-1.33[2412] |
348 |
HEY2 |
Hairy/enhancer-of-split related with YRPW motif protein 2 |
[2413] |
-2.23[2414] |
-3.93[2415] |
-4.13[2416] |
-2.14[2417] |
-4.96[2418] |
0.87[2419] |
349 |
CBL |
E3 ubiquitin-protein ligase CBL |
[2420] |
5.95[2421] |
4.98[2422] |
5.10[2423] |
6.86[2424] |
6.35[2425] |
3.87[2426] |
350 |
PORCN |
Protein-serine O-palmitoleoyltransferase porcupine |
[2427] |
3.41[2428] |
1.99[2429] |
2.96[2430] |
4.08[2431] |
5.05[2432] |
0.64[2433] |
351 |
PDGFRA |
Platelet-derived growth factor receptor alpha |
[2434] |
-2.12[2435] |
-3.01[2436] |
4.52[2437] |
2.25[2438] |
6.93[2439] |
5.44[2440] |
352 |
PDGFRB |
Platelet-derived growth factor receptor beta |
[2441] |
2.80[2442] |
3.29[2443] |
0.73[2444] |
3.58[2445] |
4.15[2446] |
3.53[2447] |
353 |
HDAC4 |
Histone deacetylase 4 |
[2448] |
4.96[2449] |
4.89[2450] |
4.56[2451] |
4.42[2452] |
4.75[2453] |
3.50[2454] |
354 |
VAV1 |
Proto-oncogene vav |
[2455] |
-7.00[2456] |
-2.08[2457] |
-3.89[2458] |
-4.36[2459] |
-5.62[2460] |
1.30[2461] |
355 |
CNKSR1 |
Connector enhancer of kinase suppressor of ras 1 |
[2462] |
3.76[2463] |
5.33[2464] |
1.12[2465] |
0.52[2466] |
-0.02[2467] |
0.51[2468] |
356 |
MAML3 |
Mastermind-like protein 3 |
[2469] |
1.12[2470] |
1.95[2471] |
4.88[2472] |
3.13[2473] |
1.75[2474] |
3.61[2475] |
357 |
PIK3R3 |
Phosphatidylinositol 3-kinase regulatory subunit gamma |
[2476] |
3.22[2477] |
3.32[2478] |
4.07[2479] |
4.89[2480] |
3.92[2481] |
2.79[2482] |
358 |
CD86 |
T-lymphocyte activation antigen CD86 |
[2483] |
[2484] |
[2485] |
-3.22[2486] |
-2.37[2487] |
-4.39[2488] |
1.46[2489] |
359 |
KSR1 |
Kinase suppressor of Ras 1 |
[2490] |
4.76[2491] |
4.55[2492] |
1.37[2493] |
3.77[2494] |
4.28[2495] |
0.85[2496] |
360 |
AKT3 |
RAC-gamma serine/threonine-protein kinase |
[2497] |
-0.35[2498] |
-2.81[2499] |
-2.22[2500] |
7.56[2501] |
6.53[2502] |
3.72[2503] |
361 |
KDR |
Vascular endothelial growth factor receptor 2 |
[2504] |
-4.13[2505] |
-5.69[2506] |
-5.08[2507] |
-0.02[2508] |
6.46[2509] |
6.41[2510] |
362 |
LCK |
Tyrosine-protein kinase Lck |
[2511] |
4.27[2512] |
4.45[2513] |
-5.65[2514] |
-3.36[2515] |
-3.55[2516] |
1.35[2517] |
363 |
KL |
Klotho |
[2518] |
-4.56[2519] |
[2520] |
[2521] |
0.33[2522] |
-4.91[2523] |
0.36[2524] |
364 |
FGF5 |
Fibroblast growth factor 5 |
[2525] |
0.51[2526] |
1.92[2527] |
1.75[2528] |
3.21[2529] |
2.90[2530] |
3.25[2531] |
365 |
EREG |
Proepiregulin |
[2532] |
3.25[2533] |
3.27[2534] |
-1.25[2535] |
0.16[2536] |
5.41[2537] |
-1.36[2538] |
366 |
ESRP1 |
Epithelial splicing regulatory protein 1 |
[2539] |
-0.43[2540] |
5.04[2541] |
2.79[2542] |
-1.33[2543] |
-1.79[2544] |
0.21[2545] |
367 |
MAML2 |
Mastermind-like protein 2 |
[2546] |
4.98[2547] |
5.70[2548] |
-0.97[2549] |
6.50[2550] |
5.38[2551] |
2.48[2552] |
368 |
DKK4 |
Dickkopf-related protein 4 |
[2553] |
3.06[2554] |
3.27[2555] |
[2556] |
[2557] |
-5.46[2558] |
-3.07[2559] |
369 |
DLL4 |
Delta-like protein 4 |
[2560] |
2.24[2561] |
3.05[2562] |
1.71[2563] |
-1.41[2564] |
-0.11[2565] |
3.31[2566] |
370 |
IHH |
Indian hedgehog protein |
[2567] |
2.55[2568] |
0.69[2569] |
6.41[2570] |
-2.57[2571] |
-3.43[2572] |
0.21[2573] |
371 |
KIAA1549 |
UPF0606 protein KIAA1549 |
[2574] |
5.75[2575] |
4.88[2576] |
5.11[2577] |
7.26[2578] |
5.43[2579] |
2.08[2580] |
372 |
CNKSR2 |
Connector enhancer of kinase suppressor of ras 2 |
[2581] |
-2.30[2582] |
-2.23[2583] |
7.30[2584] |
5.42[2585] |
3.58[2586] |
3.24[2587] |
373 |
HDAC9 |
Histone deacetylase 9 |
[2588] |
1.81[2589] |
-0.99[2590] |
3.51[2591] |
7.32[2592] |
5.43[2593] |
2.97[2594] |
374 |
DLL1 |
Delta-like protein 1 |
[2595] |
-2.86[2596] |
-1.57[2597] |
-1.60[2598] |
-5.06[2599] |
2.04[2600] |
2.62[2601] |
375 |
VWF |
von Willebrand factor |
[2602] |
2.47[2603] |
0.40[2604] |
-2.08[2605] |
1.88[2606] |
-0.70[2607] |
5.83[2608] |
376 |
FGF1 |
Fibroblast growth factor 1 |
[2609] |
-1.27[2610] |
-0.39[2611] |
-4.95[2612] |
2.31[2613] |
3.90[2614] |
0.16[2615] |
377 |
NOX4 |
NADPH oxidase 4 |
[2616] |
-1.74[2617] |
1.13[2618] |
1.23[2619] |
-0.87[2620] |
0.37[2621] |
2.21[2622] |
378 |
FGF19 |
Fibroblast growth factor 19 |
[2623] |
-0.56[2624] |
0.68[2625] |
7.32[2626] |
2.55[2627] |
-0.91[2628] |
[2629] |
379 |
JAG2 |
Protein jagged-2 |
[2630] |
4.94[2631] |
1.09[2632] |
5.03[2633] |
7.57[2634] |
4.75[2635] |
2.02[2636] |
380 |
KITLG |
Kit ligand |
[2637] |
6.94[2638] |
3.25[2639] |
8.88[2640] |
8.45[2641] |
6.65[2642] |
3.15[2643] |
381 |
CD28 |
T-cell-specific surface glycoprotein CD28 |
[2644] |
-2.50[2645] |
-1.54[2646] |
-1.61[2647] |
-0.62[2648] |
-0.67[2649] |
1.23[2650] |
382 |
KIT |
Mast/stem cell growth factor receptor Kit |
[2651] |
-1.49[2652] |
-3.28[2653] |
[2654] |
4.22[2655] |
-1.30[2656] |
3.75[2657] |
383 |
NEURL1B |
E3 ubiquitin-protein ligase NEURL1B |
[2658] |
4.60[2659] |
0.80[2660] |
2.78[2661] |
6.61[2662] |
7.47[2663] |
6.64[2664] |
384 |
CD19 |
B-lymphocyte antigen CD19 |
[2665] |
3.61[2666] |
5.39[2667] |
0.46[2668] |
0.26[2669] |
[2670] |
1.18[2671] |
385 |
SPRED3 |
Sprouty-related, EVH1 domain-containing protein 3 |
[2672] |
5.18[2673] |
3.68[2674] |
4.03[2675] |
4.31[2676] |
6.23[2677] |
-0.31[2678] |
386 |
CD80 |
T-lymphocyte activation antigen CD80 |
[2679] |
[2680] |
[2681] |
-3.77[2682] |
0.57[2683] |
-0.49[2684] |
2.74[2685] |
387 |
FLT3 |
Receptor-type tyrosine-protein kinase FLT3 |
[2686] |
[2687] |
[2688] |
-2.01[2689] |
-1.07[2690] |
[2691] |
3.03[2692] |
388 |
ITGA2B |
Integrin alpha-IIb |
[2693] |
5.10[2694] |
5.48[2695] |
5.38[2696] |
4.74[2697] |
3.11[2698] |
2.73[2699] |
389 |
ESR2 |
Estrogen receptor beta |
[2700] |
0.93[2701] |
1.40[2702] |
1.32[2703] |
2.36[2704] |
2.46[2705] |
2.64[2706] |
390 |
TRAT1 |
T-cell receptor-associated transmembrane adapter 1 |
[2707] |
[2708] |
[2709] |
[2710] |
[2711] |
[2712] |
2.90[2713] |
391 |
ICOS |
Inducible T-cell costimulator |
[2714] |
[2715] |
-1.78[2716] |
[2717] |
[2718] |
[2719] |
-0.44[2720] |
392 |
KSR2 |
Kinase suppressor of Ras 2 |
[2721] |
1.73[2722] |
0.81[2723] |
[2724] |
0.46[2725] |
[2726] |
1.43[2727] |
393 |
BCL11A |
B-cell lymphoma/leukemia 11A |
[2728] |
0.88[2729] |
[2730] |
0.78[2731] |
5.07[2732] |
[2733] |
2.42[2734] |
394 |
HGF |
Hepatocyte growth factor |
[2735] |
[2736] |
[2737] |
-0.16[2738] |
6.32[2739] |
3.36[2740] |
9.01[2741] |
395 |
HES5 |
Transcription factor HES-5 |
[2742] |
4.73[2743] |
0.60[2744] |
[2745] |
[2746] |
-0.63[2747] |
0.49[2748] |
396 |
FGF8 |
Fibroblast growth factor 8 |
[2749] |
-1.83[2750] |
-1.39[2751] |
3.00[2752] |
-0.19[2753] |
[2754] |
2.81[2755] |
397 |
FAM131B |
Protein FAM131B |
[2756] |
-2.15[2757] |
[2758] |
-2.35[2759] |
5.57[2760] |
4.54[2761] |
1.07[2762] |
398 |
FGF18 |
Fibroblast growth factor 18 |
[2763] |
3.28[2764] |
-0.75[2765] |
1.32[2766] |
2.34[2767] |
2.94[2768] |
0.70[2769] |
399 |
HEYL |
Hairy/enhancer-of-split related with YRPW motif-like protein |
[2770] |
3.74[2771] |
2.66[2772] |
4.50[2773] |
7.47[2774] |
4.59[2775] |
6.24[2776] |
400 |
KREMEN2 |
Kremen protein 2 |
[2777] |
9.39[2778] |
8.52[2779] |
8.63[2780] |
4.73[2781] |
7.04[2782] |
-0.69[2783] |
401 |
FGF9 |
Fibroblast growth factor 9 |
[2784] |
3.75[2785] |
0.19[2786] |
[2787] |
4.51[2788] |
-0.60[2789] |
0.22[2790] |
402 |
EGF |
Pro-epidermal growth factor |
[2791] |
3.46[2792] |
5.34[2793] |
8.86[2794] |
10.75[2795] |
8.18[2796] |
1.69[2797] |
403 |
CARS1 |
|
[2798] |
[2799] |
[2800] |
[2801] |
[2802] |
[2803] |
[2804] |
404 |
PSMA8 |
Proteasome subunit alpha type-7-like |
[2805] |
[2806] |
[2807] |
[2808] |
[2809] |
[2810] |
[2811] |
405 |
ERBB4 |
Receptor tyrosine-protein kinase erbB-4 |
[2812] |
[2813] |
[2814] |
[2815] |
[2816] |
[2817] |
[2818] |
406 |
FGF16 |
Fibroblast growth factor 16 |
[2819] |
[2820] |
[2821] |
[2822] |
[2823] |
[2824] |
[2825] |
407 |
FGF4 |
Fibroblast growth factor 4 |
[2826] |
[2827] |
[2828] |
[2829] |
[2830] |
[2831] |
[2832] |
408 |
WDCP |
WD repeat and coiled-coil-containing protein |
[2833] |
[2834] |
[2835] |
[2836] |
[2837] |
[2838] |
[2839] |
409 |
ERBIN |
Erbin |
[2840] |
[2841] |
[2842] |
[2843] |
[2844] |
[2845] |
[2846] |
410 |
TENT4A |
|
[2847] |
[2848] |
[2849] |
[2850] |
[2851] |
[2852] |
[2853] |
411 |
NRG3 |
Pro-neuregulin-3, membrane-bound isoform |
[2854] |
[2855] |
[2856] |
[2857] |
[2858] |
[2859] |
[2860] |
412 |
WNT3A |
Protein Wnt-3a |
[2861] |
[2862] |
[2863] |
[2864] |
[2865] |
[2866] |
[2867] |
413 |
FGF17 |
Fibroblast growth factor 17 |
[2868] |
[2869] |
[2870] |
[2871] |
[2872] |
[2873] |
[2874] |
414 |
CEP43 |
|
[2875] |
[2876] |
[2877] |
[2878] |
[2879] |
[2880] |
[2881] |
415 |
FGF10 |
Fibroblast growth factor 10 |
[2882] |
[2883] |
[2884] |
[2885] |
[2886] |
[2887] |
[2888] |
416 |
FGF22 |
Fibroblast growth factor 22 |
[2889] |
[2890] |
[2891] |
[2892] |
[2893] |
[2894] |
[2895] |
417 |
SEM1 |
Putative protein SEM1, isoform 2 |
[2896] |
[2897] |
[2898] |
[2899] |
[2900] |
[2901] |
[2902] |
418 |
FGF23 |
Fibroblast growth factor 23 |
[2903] |
[2904] |
[2905] |
[2906] |
[2907] |
[2908] |
[2909] |
419 |
FGF20 |
Fibroblast growth factor 20 |
[2910] |
[2911] |
[2912] |
[2913] |
[2914] |
[2915] |
[2916] |
420 |
FGF3 |
Fibroblast growth factor 3 |
[2917] |
[2918] |
[2919] |
[2920] |
[2921] |
[2922] |
[2923] |
421 |
NEURL1 |
E3 ubiquitin-protein ligase NEURL1 |
[2924] |
[2925] |
[2926] |
[2927] |
[2928] |
[2929] |
[2930] |
422 |
DKK2 |
Dickkopf-related protein 2 |
[2931] |
[2932] |
[2933] |
[2934] |
[2935] |
[2936] |
[2937] |
423 |
AMER1 |
APC membrane recruitment protein 1 |
[2938] |
[2939] |
[2940] |
[2941] |
[2942] |
[2943] |
[2944] |
424 |
FOXO6 |
Forkhead box protein O6 |
[2945] |
[2946] |
[2947] |
[2948] |
[2949] |
[2950] |
[2951] |
425 |
CAMK2A |
Calcium/calmodulin-dependent protein kinase type II subunit alpha |
[2952] |
[2953] |
[2954] |
[2955] |
[2956] |
[2957] |
[2958] |
426 |
NRG2 |
Pro-neuregulin-2, membrane-bound isoform |
[2959] |
[2960] |
[2961] |
[2962] |
[2963] |
[2964] |
[2965] |
427 |
FGF6 |
Fibroblast growth factor 6 |
[2966] |
[2967] |
[2968] |
[2969] |
[2970] |
[2971] |
[2972] |
428 |
PSMB11 |
Proteasome subunit beta type-11 |
[2973] |
[2974] |
[2975] |
[2976] |
[2977] |
[2978] |
[2979] |
429 |
ALK |
ALK tyrosine kinase receptor |
[2980] |
[2981] |
[2982] |
[2983] |
[2984] |
[2985] |
[2986] |
430 |
DHH |
Desert hedgehog protein |
[2987] |
[2988] |
[2989] |
[2990] |
[2991] |
[2992] |
[2993] |
431 |
KDM7A |
Lysine-specific demethylase 7A |
[2994] |
[2995] |
[2996] |
[2997] |
[2998] |
[2999] |
[3000] |
432 |
EPGN |
Epigen |
[3001] |
[3002] |
[3003] |
[3004] |
[3005] |
[3006] |
[3007] |
|
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|
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