REACTOME_DISEASES_OF_MITOTIC_CELL_CYCLE | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | ANAPC11 | Anaphase-promoting complex subunit 11 | [1] | -2.58[2] | -1.92[3] | -2.36[4] | -2.72[5] | -2.52[6] | -1.19[7] |
2 | CDKN1A | Cyclin-dependent kinase inhibitor 1 | [8] | 0.09[9] | -1.08[10] | -3.79[11] | -2.39[12] | -0.01[13] | -1.62[14] |
3 | CDC26 | Anaphase-promoting complex subunit CDC26 | [15] | -3.52[16] | -2.83[17] | -2.88[18] | -3.43[19] | -2.71[20] | -2.00[21] |
4 | UBE2E1 | Ubiquitin-conjugating enzyme E2 E1 | [22] | -1.70[23] | -1.25[24] | -0.55[25] | -0.88[26] | -0.80[27] | -2.60[28] |
5 | CCND1 | G1/S-specific cyclin-D1 | [29] | 2.31[30] | 0.02[31] | 0.83[32] | 1.48[33] | -0.18[34] | 1.26[35] |
6 | CDK4 | Cyclin-dependent kinase 4 | [36] | 0.59[37] | 1.38[38] | 1.00[39] | -0.22[40] | 0.25[41] | -0.63[42] |
7 | ANAPC16 | Anaphase-promoting complex subunit 16 | [43] | -0.56[44] | 0.37[45] | -0.81[46] | -0.83[47] | -0.77[48] | 0.75[49] |
8 | ANAPC5 | Anaphase-promoting complex subunit 5 | [50] | 0.13[51] | 1.01[52] | 1.15[53] | -0.06[54] | 0.22[55] | 0.92[56] |
9 | DAXX | Death domain-associated protein 6 | [57] | -0.58[58] | -0.51[59] | -0.92[60] | -0.25[61] | -0.55[62] | -0.75[63] |
10 | TFDP1 | Transcription factor Dp-1 | [64] | -0.08[65] | -0.54[66] | -0.49[67] | 0.21[68] | 0.60[69] | -0.93[70] |
11 | CDKN1B | Cyclin-dependent kinase inhibitor 1B | [71] | -0.83[72] | -0.18[73] | 0.00[74] | -1.51[75] | -1.22[76] | -0.70[77] |
12 | CDC27 | Cell division cycle protein 27 homolog | [78] | -0.53[79] | 0.52[80] | -0.15[81] | 0.78[82] | 0.14[83] | 0.36[84] |
13 | CDC16 | Cell division cycle protein 16 homolog | [85] | -1.24[86] | -0.80[87] | -1.47[88] | -0.82[89] | -0.56[90] | 0.08[91] |
14 | CDK2 | Cyclin-dependent kinase 2 | [92] | -1.16[93] | -0.78[94] | -0.42[95] | -0.42[96] | -0.01[97] | -1.98[98] |
15 | UBE2C | Ubiquitin-conjugating enzyme E2 C | [99] | -0.98[100] | -0.39[101] | 0.36[102] | -0.27[103] | 0.44[104] | -3.59[105] |
16 | UBE2S | Ubiquitin-conjugating enzyme E2 S | [106] | -0.30[107] | -0.51[108] | 1.66[109] | 0.56[110] | 1.74[111] | -2.38[112] |
17 | CDC23 | Cell division cycle protein 23 homolog | [113] | -0.37[114] | 0.04[115] | 0.28[116] | 0.63[117] | 0.16[118] | 0.41[119] |
18 | FZR1 | Fizzy-related protein homolog | [120] | 0.00[121] | -0.14[122] | -0.07[123] | -0.36[124] | 0.05[125] | 0.83[126] |
19 | ANAPC7 | Anaphase-promoting complex subunit 7 | [127] | 0.26[128] | 0.87[129] | 0.32[130] | 0.50[131] | 0.58[132] | 0.40[133] |
20 | ANAPC2 | Anaphase-promoting complex subunit 2 | [134] | -0.14[135] | -0.49[136] | 0.11[137] | -0.36[138] | -0.58[139] | 0.26[140] |
21 | CDK6 | Cyclin-dependent kinase 6 | [141] | 1.30[142] | 2.21[143] | 0.60[144] | 0.52[145] | 1.14[146] | 2.28[147] |
22 | ANAPC1 | Anaphase-promoting complex subunit 1 | [148] | 1.66[149] | 2.06[150] | 1.93[151] | 1.52[152] | 1.36[153] | 1.66[154] |
23 | CCND3 | G1/S-specific cyclin-D3 | [155] | 0.21[156] | -0.64[157] | -2.29[158] | 3.27[159] | 2.26[160] | 0.86[161] |
24 | SKP2 | S-phase kinase-associated protein 2 | [162] | 0.57[163] | 1.24[164] | 2.36[165] | 0.86[166] | 0.77[167] | 1.29[168] |
25 | CCNE1 | G1/S-specific cyclin-E1 | [169] | 0.49[170] | 0.82[171] | -1.01[172] | -0.80[173] | -0.39[174] | -4.42[175] |
26 | RB1 | Retinoblastoma-associated protein | [176] | 0.47[177] | 1.19[178] | 1.73[179] | 1.88[180] | 2.02[181] | 1.69[182] |
27 | ANAPC4 | Anaphase-promoting complex subunit 4 | [183] | -0.55[184] | 0.59[185] | 0.90[186] | 0.79[187] | 0.08[188] | 1.19[189] |
28 | E2F1 | Transcription factor E2F1 | [190] | 1.20[191] | 1.27[192] | 1.38[193] | 1.47[194] | 1.73[195] | -3.41[196] |
29 | ATRX | Transcriptional regulator ATRX | [197] | -0.09[198] | 2.02[199] | 2.57[200] | 2.20[201] | 1.55[202] | 3.50[203] |
30 | UBE2D1 | Ubiquitin-conjugating enzyme E2 D1 | [204] | 0.05[205] | 1.13[206] | 1.46[207] | 1.12[208] | 0.70[209] | 0.71[210] |
31 | E2F3 | Transcription factor E2F3 | [211] | 0.97[212] | 1.01[213] | 0.25[214] | 2.23[215] | 1.50[216] | 0.04[217] |
32 | ANAPC10 | Anaphase-promoting complex subunit 10 | [218] | -0.98[219] | 0.12[220] | -0.51[221] | -0.62[222] | -0.02[223] | 0.33[224] |
33 | TFDP2 | Transcription factor Dp-2 | [225] | 1.16[226] | 2.07[227] | 2.06[228] | 1.99[229] | 2.03[230] | 2.56[231] |
34 | CCNE2 | G1/S-specific cyclin-E2 | [232] | -0.32[233] | 0.29[234] | -0.20[235] | 2.64[236] | 2.36[237] | -0.14[238] |
35 | CCND2 | G1/S-specific cyclin-D2 | [239] | 2.40[240] | 1.19[241] | -5.03[242] | -4.85[243] | -2.12[244] | 2.06[245] |
36 | CDKN1C | Cyclin-dependent kinase inhibitor 1C | [246] | [247] | -5.79[248] | 0.89[249] | 0.77[250] | -0.04[251] | 1.67[252] |
37 | E2F2 | Transcription factor E2F2 | [253] | 3.50[254] | 4.61[255] | 4.10[256] | 3.65[257] | 3.80[258] | 1.63[259] |
38 | ANAPC15 | Anaphase-promoting complex subunit 15 | [260] | [261] | [262] | [263] | [264] | [265] | [266] |