REACTOME_DISEASES_ASSOCIATED_WITH_N_GLYCOSYLATION_OF_PROTEINS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 MPDU1 Mannose-P-dolichol utilization defect 1 protein [1] -0.38[2] -0.19[3] -1.08[4] -0.39[5] -0.77[6] -0.68[7]
2 B4GALT1 Beta-1,4-galactosyltransferase 1 [8] -0.25[9] -0.29[10] 0.50[11] 0.36[12] 1.59[13] 0.43[14]
3 ALG3 Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase [15] -0.67[16] -0.91[17] -0.41[18] -1.39[19] -1.20[20] -0.33[21]
4 ALG8 Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase 0.23[22] -0.41[23] -0.02[24] -0.19[25] -0.88[26] -0.40[27]
5 MOGS Mannosyl-oligosaccharide glucosidase [28] 0.71[29] 0.97[30] 0.22[31] -0.02[32] -0.33[33] -0.01[34]
6 MGAT2 Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase -0.39[35] 0.20[36] 0.48[37] 0.03[38] -0.07[39] -0.01[40]
7 MAN1B1 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 0.66[41] 0.40[42] 0.56[43] 0.57[44] -0.25[45] -0.31[46]
8 ALG2 Alpha-1,3/1,6-mannosyltransferase ALG2 [47] -0.37[48] 0.43[49] -0.56[50] -0.32[51] -0.17[52] 0.20[53]
9 DPAGT1 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase 0.03[54] -0.37[55] -0.31[56] 0.45[57] -1.06[58] 0.09[59]
10 ALG14 UDP-N-acetylglucosamine transferase subunit ALG14 homolog [60] -1.79[61] -0.81[62] -1.74[63] -1.00[64] -2.19[65] -0.83[66]
11 ALG13 Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 -1.00[67] -0.06[68] 0.01[69] 0.46[70] -0.49[71] 0.52[72]
12 ALG12 Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase [73] -0.02[74] 0.12[75] 1.19[76] -0.34[77] -0.71[78] 0.67[79]
13 ALG11 GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase [80] -1.78[81] -0.96[82] -0.55[83] -1.50[84] -2.05[85] -0.89[86]
14 RFT1 Protein RFT1 homolog [87] 0.73[88] 0.38[89] -0.56[90] 0.00[91] 0.45[92] 0.08[93]
15 ALG1 Chitobiosyldiphosphodolichol beta-mannosyltransferase [94] 1.35[95] 0.03[96] -0.37[97] -0.10[98] -0.57[99] 0.37[100]
16 ALG9 Alpha-1,2-mannosyltransferase ALG9 [101] 1.87[102] 1.44[103] 0.74[104] 2.47[105] 1.22[106] 1.99[107]
17 ALG6 Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase [108] 0.35[109] 0.68[110] 1.32[111] 1.64[112] 1.41[113] 0.88[114]
[1]
ref_hepatocyte MPDU1
Mean 25.7
Standard deviation 22
Values 6.1 9.7 13 56 43
[2]
HepG2 MPDU1
Mean 47.6
Standard deviation 9.8
Values 41 54
[3]
HepG2.C3A MPDU1
Mean 45.7
Standard deviation 13
Values 36 55
[4]
HuH.7 MPDU1
Mean 26.5
Standard deviation 9
Values 31 16 32
[5]
SNU475 MPDU1
Mean 27
Standard deviation 3.6
Values 24 30
[6]
THLE MPDU1
Mean 34.7
Standard deviation 4.7
Values 31 38
[7]
liver MPDU1
Mean 26.4
Standard deviation 13
Values 36 18 39 12
[8]
ref_hepatocyte B4GALT1
Mean 24.8
Standard deviation 5.2
Values 17 26 28 31 23
[9]
HepG2 B4GALT1
Mean 50.3
Standard deviation 11
Values 58 42
[10]
HepG2.C3A B4GALT1
Mean 41.3
Standard deviation 12
Values 50 32
[11]
HuH.7 B4GALT1
Mean 76.8
Standard deviation 16
Values 83 90 58
[12]
SNU475 B4GALT1
Mean 44.1
Standard deviation 8.5
Values 50 38
[13]
THLE B4GALT1
Mean 172
Standard deviation 9.4
Values 1.7e+02 1.8e+02
[14]
liver B4GALT1
Mean 55
Standard deviation 12
Values 52 46 73 49
[15]
ref_hepatocyte ALG3
Mean 20.5
Standard deviation 15
Values 6.8 4.9 34 39 18
[16]
HepG2 ALG3
Mean 31.1
Standard deviation 5.8
Values 35 27
[17]
HepG2.C3A ALG3
Mean 22.1
Standard deviation 4.3
Values 25 19
[18]
HuH.7 ALG3
Mean 33.6
Standard deviation 8.9
Values 41 24 36
[19]
SNU475 ALG3
Mean 10.8
Standard deviation 3.4
Values 8.4 13
[20]
THLE ALG3
Mean 20.5
Standard deviation 0.85
Values 20 21
[21]
liver ALG3
Mean 26.9
Standard deviation 21
Values 39 7.1 51 11
[22]
ref_hepatocyte ALG8
Mean 14
Standard deviation 7.9
Values 15 11 2.6 24 18
[23]
HepG2 ALG8
Mean 39.7
Standard deviation 5.6
Values 36 44
[24]
HepG2.C3A ALG8
Mean 21.4
Standard deviation 5.9
Values 17 26
[25]
HuH.7 ALG8
Mean 30.2
Standard deviation 5.5
Values 34 24 32
[26]
SNU475 ALG8
Mean 17
Standard deviation 1.6
Values 16 18
[27]
THLE ALG8
Mean 17.5
Standard deviation 2.1
Values 16 19
[28]
liver ALG8
Mean 17.5
Standard deviation 10
Values 24 10 28 7.7
[29]
ref_hepatocyte MOGS
Mean 13.7
Standard deviation 7.1
Values 6.6 7.3 14 24 17
[30]
HepG2 MOGS
Mean 54.2
Standard deviation 3.8
Values 57 51
[31]
HepG2.C3A MOGS
Mean 54.5
Standard deviation 22
Values 70 39
[32]
HuH.7 MOGS
Mean 34.9
Standard deviation 4.8
Values 35 30 39
[33]
SNU475 MOGS
Mean 18.7
Standard deviation 0.31
Values 18 19
[34]
THLE MOGS
Mean 25.2
Standard deviation 2.4
Values 24 27
[35]
liver MOGS
Mean 22.5
Standard deviation 3.6
Values 20 19 24 27
[36]
ref_hepatocyte MGAT2
Mean 13.5
Standard deviation 4.1
Values 12 11 20 9 16
[37]
HepG2 MGAT2
Mean 24.8
Standard deviation 8
Values 19 30
[38]
HepG2.C3A MGAT2
Mean 31.4
Standard deviation 9
Values 25 38
[39]
HuH.7 MGAT2
Mean 41.1
Standard deviation 4
Values 42 37 45
[40]
SNU475 MGAT2
Mean 19
Standard deviation 2
Values 20 18
[41]
THLE MGAT2
Mean 29.5
Standard deviation 8.6
Values 23 36
[42]
liver MGAT2
Mean 22.1
Standard deviation 2.6
Values 22 25 19 22
[43]
ref_hepatocyte MAN1B1
Mean 12.6
Standard deviation 4
Values 10 18 7.3 15 13
[44]
HepG2 MAN1B1
Mean 48
Standard deviation 5.2
Values 52 44
[45]
HepG2.C3A MAN1B1
Mean 33.8
Standard deviation 8.4
Values 40 28
[46]
HuH.7 MAN1B1
Mean 40.7
Standard deviation 9.9
Values 44 30 48
[47]
SNU475 MAN1B1
Mean 25.9
Standard deviation 7
Values 31 21
[48]
THLE MAN1B1
Mean 24.4
Standard deviation 7.8
Values 19 30
[49]
liver MAN1B1
Mean 16.8
Standard deviation 4.7
Values 18 13 23 13
[50]
ref_hepatocyte ALG2
Mean 11.5
Standard deviation 4.1
Values 7.8 6.7 13 15 15
[51]
HepG2 ALG2
Mean 21.5
Standard deviation 6
Values 17 26
[52]
HepG2.C3A ALG2
Mean 31.5
Standard deviation 7.6
Values 37 26
[53]
HuH.7 ALG2
Mean 17
Standard deviation 2.1
Values 15 19 17
[54]
SNU475 ALG2
Mean 12.7
Standard deviation 0.3
Values 13 12
[55]
THLE ALG2
Mean 23.6
Standard deviation 2
Values 22 25
[56]
liver ALG2
Mean 21.7
Standard deviation 6.5
Values 20 19 31 17
[57]
ref_hepatocyte DPAGT1
Mean 11.1
Standard deviation 7.6
Values 5.3 6.2 10 24 9.5
[58]
HepG2 DPAGT1
Mean 27.3
Standard deviation 2.6
Values 29 26
[59]
HepG2.C3A DPAGT1
Mean 17.5
Standard deviation 2.1
Values 19 16
[60]
HuH.7 DPAGT1
Mean 19.7
Standard deviation 4.8
Values 23 14 22
[61]
SNU475 DPAGT1
Mean 21.1
Standard deviation 4
Values 18 24
[62]
THLE DPAGT1
Mean 12.3
Standard deviation 1.3
Values 11 13
[63]
liver DPAGT1
Mean 19.5
Standard deviation 16
Values 23 6.7 41 7.5
[64]
ref_hepatocyte ALG14
Mean 7.74
Standard deviation 4.9
Values 5.4 6.8 1.7 10 15
[65]
HepG2 ALG14
Mean 5.38
Standard deviation 1.6
Values 4.3 6.5
[66]
HepG2.C3A ALG14
Mean 8.98
Standard deviation 2.1
Values 7.5 10
[67]
HuH.7 ALG14
Mean 5.05
Standard deviation 1.1
Values 4.6 4.3 6.3
[68]
SNU475 ALG14
Mean 5.33
Standard deviation 2
Values 6.7 3.9
[69]
THLE ALG14
Mean 3.9
Standard deviation 0.82
Values 3.3 4.5
[70]
liver ALG14
Mean 7.17
Standard deviation 5.7
Values 14 2.5 9.8 2.5
[71]
ref_hepatocyte ALG13
Mean 5.8
Standard deviation 2.4
Values 4.8 9.8 4.4 3.7 6.3
[72]
HepG2 ALG13
Mean 6.98
Standard deviation 0.46
Values 6.7 7.3
[73]
HepG2.C3A ALG13
Mean 11.3
Standard deviation 2.3
Values 9.6 13
[74]
HuH.7 ALG13
Mean 12.8
Standard deviation 2.6
Values 14 9.7 14
[75]
SNU475 ALG13
Mean 11
Standard deviation 2.2
Values 13 9.5
[76]
THLE ALG13
Mean 9.49
Standard deviation 1.5
Values 11 8.4
[77]
liver ALG13
Mean 13.7
Standard deviation 4.1
Values 16 13 17 8
[78]
ref_hepatocyte ALG12
Mean 5.65
Standard deviation 3.4
Values 4.2 3.5 2.1 10 8
[79]
HepG2 ALG12
Mean 13.4
Standard deviation 0.054
Values 13 13
[80]
HepG2.C3A ALG12
Mean 12.5
Standard deviation 2.2
Values 14 11
[81]
HuH.7 ALG12
Mean 28.2
Standard deviation 3.2
Values 32 26 27
[82]
SNU475 ALG12
Mean 6.15
Standard deviation 1.7
Values 7.4 4.9
[83]
THLE ALG12
Mean 7.94
Standard deviation 1.7
Values 6.8 9.1
[84]
liver ALG12
Mean 14.8
Standard deviation 3.4
Values 15 11 19 14
[85]
ref_hepatocyte ALG11
Mean 5.43
Standard deviation 5.9
Values 11 12 1.6 1 0.85
[86]
HepG2 ALG11
Mean 3.82
Standard deviation 0.87
Values 3.2 4.4
[87]
HepG2.C3A ALG11
Mean 5.67
Standard deviation 1.2
Values 4.8 6.5
[88]
HuH.7 ALG11
Mean 8.09
Standard deviation 1.8
Values 7.6 10 6.6
[89]
SNU475 ALG11
Mean 2.64
Standard deviation 0.7
Values 3.1 2.1
[90]
THLE ALG11
Mean 3.02
Standard deviation 0.51
Values 2.7 3.4
[91]
liver ALG11
Mean 4.82
Standard deviation 0.63
Values 4.4 4.6 5.8 4.6
[92]
ref_hepatocyte RFT1
Mean 4.99
Standard deviation 2.2
Values 6.2 7.5 5.6 3.4 2.2
[93]
HepG2 RFT1
Mean 20
Standard deviation 2.6
Values 22 18
[94]
HepG2.C3A RFT1
Mean 13.2
Standard deviation 0.58
Values 13 14
[95]
HuH.7 RFT1
Mean 7.38
Standard deviation 2.1
Values 8.5 5 8.6
[96]
SNU475 RFT1
Mean 6.9
Standard deviation 0.4
Values 6.6 7.2
[97]
THLE RFT1
Mean 15.7
Standard deviation 2.9
Values 14 18
[98]
liver RFT1
Mean 8.7
Standard deviation 1.5
Values 6.8 8.6 10 9
[99]
ref_hepatocyte ALG1
Mean 4.94
Standard deviation 1.7
Values 6 4.7 3 7.3 3.7
[100]
HepG2 ALG1
Mean 30.4
Standard deviation 2
Values 29 32
[101]
HepG2.C3A ALG1
Mean 10.3
Standard deviation 0.12
Values 10 10
[102]
HuH.7 ALG1
Mean 8.37
Standard deviation 1.2
Values 9.2 7 8.9
[103]
SNU475 ALG1
Mean 6.4
Standard deviation 0.83
Values 5.8 7
[104]
THLE ALG1
Mean 7.67
Standard deviation 2.6
Values 5.9 9.5
[105]
liver ALG1
Mean 10.5
Standard deviation 3.5
Values 11 7.9 15 7.7
[106]
ref_hepatocyte ALG9
Mean 2.07
Standard deviation 0.52
Values 2.8 1.5 1.7 2.2 2.2
[107]
HepG2 ALG9
Mean 18.2
Standard deviation 0.053
Values 18 18
[108]
HepG2.C3A ALG9
Mean 11.4
Standard deviation 2.9
Values 13 9.3
[109]
HuH.7 ALG9
Mean 7.56
Standard deviation 1.3
Values 6.8 9 6.8
[110]
SNU475 ALG9
Mean 15.9
Standard deviation 3
Values 14 18
[111]
THLE ALG9
Mean 11.1
Standard deviation 1.6
Values 10 12
[112]
liver ALG9
Mean 13.6
Standard deviation 3.6
Values 8.8 16 13 17
[113]
ref_hepatocyte ALG6
Mean 1.27
Standard deviation 0.59
Values 1 0.45 1.3 1.5 2
[114]
HepG2 ALG6
Mean 3.91
Standard deviation 1.1
Values 3.1 4.7
[115]
HepG2.C3A ALG6
Mean 4.13
Standard deviation 1.4
Values 3.1 5.1
[116]
HuH.7 ALG6
Mean 6.94
Standard deviation 2
Values 8.8 4.8 7.2
[117]
SNU475 ALG6
Mean 5.49
Standard deviation 0.73
Values 6 5
[118]
THLE ALG6
Mean 7.76
Standard deviation 0.76
Values 7.2 8.3
[119]
liver ALG6
Mean 3.87
Standard deviation 1.2
Values 3.7 3.6 5.6 2.6