REACTOME_DISEASES_ASSOCIATED_WITH_GLYCOSYLATION_PRECURSOR_BIOSYNTHESIS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 PGM1 Phosphoglucomutase-1 [1] -1.43[2] -0.66[3] 0.20[4] -0.42[5] -0.72[6] 0.57[7]
2 DPM1 Dolichol-phosphate mannosyltransferase subunit 1 [8] -1.25[9] -0.65[10] -1.37[11] -0.96[12] -1.15[13] -2.46[14]
3 CTSA Lysosomal protective protein [15] 1.34[16] -0.04[17] -0.32[18] 1.31[19] 0.56[20] -0.13[21]
4 NEU1 Sialidase-1 [22] 0.90[23] 0.25[24] -0.75[25] -0.71[26] -0.58[27] -1.76[28]
5 DPM3 Dolichol-phosphate mannosyltransferase subunit 3 [29] -4.35[30] -3.15[31] -2.75[32] -3.09[33] -2.85[34] -3.15[35]
6 GALK1 Galactokinase [36] -1.23[37] -0.73[38] -0.59[39] -1.37[40] -1.69[41] -0.26[42]
7 GALE UDP-glucose 4-epimerase [43] -0.14[44] 1.14[45] -0.39[46] 0.52[47] -0.10[48] -0.78[49]
8 GALT Galactose-1-phosphate uridylyltransferase [50] -2.25[51] -1.69[52] -1.20[53] -2.52[54] -1.61[55] 0.48[56]
9 PMM2 Phosphomannomutase 2 [57] 0.04[58] -0.26[59] -0.04[60] -1.23[61] -0.87[62] -0.29[63]
10 GLB1 Beta-galactosidase [64] 0.64[65] 0.23[66] 1.61[67] 0.23[68] 1.26[69] -0.04[70]
11 GNE Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase -0.95[71] -0.21[72] 0.52[73] -0.49[74] 0.22[75] 2.25[76]
12 NUS1 Dehydrodolichyl diphosphate synthase complex subunit NUS1 [77] 0.98[78] 1.59[79] 0.69[80] 1.27[81] 1.98[82] 0.33[83]
13 GFPT1 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 [84] 1.40[85] 2.37[86] 2.51[87] 2.00[88] 2.07[89] 2.45[90]
14 DPM2 Dolichol phosphate-mannose biosynthesis regulatory protein [91] -0.19[92] -0.05[93] -0.10[94] 0.40[95] 0.84[96] -0.70[97]
15 MPI Mannose-6-phosphate isomerase [98] 0.52[99] 0.03[100] 1.27[101] 0.24[102] 0.68[103] -0.11[104]
16 DHDDS Dehydrodolichyl diphosphate synthase complex subunit DHDDS [105] -0.14[106] 0.56[107] 0.14[108] 1.12[109] 0.88[110] -0.69[111]
17 DOLK Dolichol kinase [112] -0.06[113] -0.51[114] 0.04[115] 0.35[116] 0.64[117] -0.01[118]
18 SRD5A3 Polyprenol reductase [119] 0.64[120] 0.21[121] 0.65[122] 0.71[123] 1.16[124] 0.28[125]
[1]
ref_hepatocyte PGM1
Mean 48.7
Standard deviation 37
Values 17 38 13 81 94
[2]
HepG2 PGM1
Mean 40.3
Standard deviation 11
Values 32 48
[3]
HepG2.C3A PGM1
Mean 63.1
Standard deviation 8.8
Values 69 57
[4]
HuH.7 PGM1
Mean 87
Standard deviation 8.2
Values 96 80 84
[5]
SNU475 PGM1
Mean 39.9
Standard deviation 9.8
Values 47 33
[6]
THLE PGM1
Mean 30.8
Standard deviation 0.38
Values 31 31
[7]
liver PGM1
Mean 114
Standard deviation 21
Values 1.3e+02 91 1.3e+02 1e+02
[8]
ref_hepatocyte DPM1
Mean 42.8
Standard deviation 19
Values 71 49 42 25 27
[9]
HepG2 DPM1
Mean 40.1
Standard deviation 7.2
Values 35 45
[10]
HepG2.C3A DPM1
Mean 55.9
Standard deviation 18
Values 43 69
[11]
HuH.7 DPM1
Mean 25.7
Standard deviation 5.6
Values 26 20 31
[12]
SNU475 DPM1
Mean 24.2
Standard deviation 4.2
Values 27 21
[13]
THLE DPM1
Mean 20
Standard deviation 1.6
Values 19 21
[14]
liver DPM1
Mean 12.3
Standard deviation 7.1
Values 20 6.9 16 5.8
[15]
ref_hepatocyte CTSA
Mean 38
Standard deviation 25
Values 77 17 14 45 37
[16]
HepG2 CTSA
Mean 215
Standard deviation 48
Values 1.8e+02 2.5e+02
[17]
HepG2.C3A CTSA
Mean 75.5
Standard deviation 5.5
Values 72 79
[18]
HuH.7 CTSA
Mean 47.1
Standard deviation 9.1
Values 51 37 53
[19]
SNU475 CTSA
Mean 103
Standard deviation 12
Values 1.1e+02 95
[20]
THLE CTSA
Mean 58.4
Standard deviation 14
Values 49 68
[21]
liver CTSA
Mean 54.8
Standard deviation 50
Values 1.1e+02 12 88 11
[22]
ref_hepatocyte NEU1
Mean 37.6
Standard deviation 42
Values 1.1e+02 16 16 24 19
[23]
HepG2 NEU1
Mean 157
Standard deviation 34
Values 1.3e+02 1.8e+02
[24]
HepG2.C3A NEU1
Mean 91.4
Standard deviation 4.1
Values 89 94
[25]
HuH.7 NEU1
Mean 34.6
Standard deviation 13
Values 24 49 32
[26]
SNU475 NEU1
Mean 25.2
Standard deviation 0.97
Values 26 25
[27]
THLE NEU1
Mean 26.2
Standard deviation 7.6
Values 21 32
[28]
liver NEU1
Mean 17.6
Standard deviation 6.7
Values 25 12 21 12
[29]
ref_hepatocyte DPM3
Mean 34.6
Standard deviation 36
Values 3.2 2.6 29 50 88
[30]
HepG2 DPM3
Mean 3.78
Standard deviation 0.79
Values 3.2 4.3
[31]
HepG2.C3A DPM3
Mean 7.98
Standard deviation 0.79
Values 8.5 7.4
[32]
HuH.7 DPM3
Mean 7.96
Standard deviation 2.8
Values 7 5.7 11
[33]
SNU475 DPM3
Mean 4.45
Standard deviation 1.1
Values 5.2 3.6
[34]
THLE DPM3
Mean 5
Standard deviation 0.46
Values 5.3 4.7
[35]
liver DPM3
Mean 6.18
Standard deviation 5.3
Values 11 1.7 11 1.5
[36]
ref_hepatocyte GALK1
Mean 31.3
Standard deviation 20
Values 23 18 10 57 48
[37]
HepG2 GALK1
Mean 29.8
Standard deviation 8.4
Values 36 24
[38]
HepG2.C3A GALK1
Mean 38.7
Standard deviation 11
Values 47 31
[39]
HuH.7 GALK1
Mean 32.4
Standard deviation 1.1
Values 32 31 34
[40]
SNU475 GALK1
Mean 13.3
Standard deviation 0.12
Values 13 13
[41]
THLE GALK1
Mean 10.1
Standard deviation 0.32
Values 9.9 10
[42]
liver GALK1
Mean 41.4
Standard deviation 44
Values 1.1e+02 8.8 25 25
[43]
ref_hepatocyte GALE
Mean 19.2
Standard deviation 3.1
Values 21 14 19 21 22
[44]
HepG2 GALE
Mean 38.9
Standard deviation 8.2
Values 45 33
[45]
HepG2.C3A GALE
Mean 86.4
Standard deviation 3.4
Values 89 84
[46]
HuH.7 GALE
Mean 22.6
Standard deviation 7.4
Values 20 17 31
[47]
SNU475 GALE
Mean 30.3
Standard deviation 2.2
Values 32 29
[48]
THLE GALE
Mean 18.7
Standard deviation 2.3
Values 17 20
[49]
liver GALE
Mean 17.7
Standard deviation 8.6
Values 25 12 25 9
[50]
ref_hepatocyte GALT
Mean 18.7
Standard deviation 18
Values 7.8 4.2 4.3 42 35
[51]
HepG2 GALT
Mean 8.81
Standard deviation 0.24
Values 8.6 9
[52]
HepG2.C3A GALT
Mean 11.9
Standard deviation 2.5
Values 14 10
[53]
HuH.7 GALT
Mean 12.6
Standard deviation 1.5
Values 11 12 14
[54]
SNU475 GALT
Mean 3.59
Standard deviation 0.62
Values 4 3.2
[55]
THLE GALT
Mean 6.37
Standard deviation 0.48
Values 6.7 6
[56]
liver GALT
Mean 41.3
Standard deviation 25
Values 74 19 47 26
[57]
ref_hepatocyte PMM2
Mean 16.4
Standard deviation 5.6
Values 14 15 25 19 9.9
[58]
HepG2 PMM2
Mean 37.8
Standard deviation 2.8
Values 36 40
[59]
HepG2.C3A PMM2
Mean 28
Standard deviation 0.27
Values 28 28
[60]
HuH.7 PMM2
Mean 24.8
Standard deviation 4.5
Values 24 21 30
[61]
SNU475 PMM2
Mean 7.66
Standard deviation 0.074
Values 7.6 7.7
[62]
THLE PMM2
Mean 9.35
Standard deviation 2.7
Values 7.5 11
[63]
liver PMM2
Mean 21.3
Standard deviation 9.8
Values 20 16 35 14
[64]
ref_hepatocyte GLB1
Mean 15.3
Standard deviation 5.7
Values 22 9.9 8.6 18 18
[65]
HepG2 GLB1
Mean 53.1
Standard deviation 4.7
Values 56 50
[66]
HepG2.C3A GLB1
Mean 36.7
Standard deviation 8.2
Values 42 31
[67]
HuH.7 GLB1
Mean 72.4
Standard deviation 9.9
Values 62 81 75
[68]
SNU475 GLB1
Mean 19.7
Standard deviation 1.4
Values 19 21
[69]
THLE GLB1
Mean 38.2
Standard deviation 4.9
Values 35 42
[70]
liver GLB1
Mean 23.6
Standard deviation 8.2
Values 23 20 35 16
[71]
ref_hepatocyte GNE
Mean 12.1
Standard deviation 8.9
Values 6.7 6.1 7.6 13 27
[72]
HepG2 GNE
Mean 14
Standard deviation 0.42
Values 14 14
[73]
HepG2.C3A GNE
Mean 21.4
Standard deviation 2.8
Values 23 19
[74]
HuH.7 GNE
Mean 27
Standard deviation 1.8
Values 29 27 25
[75]
SNU475 GNE
Mean 9.45
Standard deviation 1.4
Values 10 8.5
[76]
THLE GNE
Mean 14.7
Standard deviation 1.9
Values 13 16
[77]
liver GNE
Mean 91.4
Standard deviation 38
Values 72 1e+02 51 1.4e+02
[78]
ref_hepatocyte NUS1
Mean 12
Standard deviation 2.4
Values 15 11 14 11 9
[79]
HepG2 NUS1
Mean 52.9
Standard deviation 7
Values 48 58
[80]
HepG2.C3A NUS1
Mean 74.2
Standard deviation 1.1
Values 73 75
[81]
HuH.7 NUS1
Mean 30.1
Standard deviation 1
Values 29 30 31
[82]
SNU475 NUS1
Mean 31.7
Standard deviation 7.9
Values 37 26
[83]
THLE NUS1
Mean 49.4
Standard deviation 8
Values 44 55
[84]
liver NUS1
Mean 23.9
Standard deviation 2.2
Values 23 26 21 25
[85]
ref_hepatocyte GFPT1
Mean 8.56
Standard deviation 3.7
Values 15 6.9 8.2 6.5 6
[86]
HepG2 GFPT1
Mean 50.6
Standard deviation 7.7
Values 45 56
[87]
HepG2.C3A GFPT1
Mean 91
Standard deviation 30
Values 1.1e+02 70
[88]
HuH.7 GFPT1
Mean 75.6
Standard deviation 15
Values 77 89 60
[89]
SNU475 GFPT1
Mean 37.6
Standard deviation 4.4
Values 41 35
[90]
THLE GFPT1
Mean 37.5
Standard deviation 3
Values 40 35
[91]
liver GFPT1
Mean 74.1
Standard deviation 24
Values 40 96 84 77
[92]
ref_hepatocyte DPM2
Mean 7.81
Standard deviation 5.5
Values 1.1 3.2 14 12 9
[93]
HepG2 DPM2
Mean 15.3
Standard deviation 1.9
Values 17 14
[94]
HepG2.C3A DPM2
Mean 15.5
Standard deviation 0.53
Values 15 16
[95]
HuH.7 DPM2
Mean 11.3
Standard deviation 4.1
Values 12 7 15
[96]
SNU475 DPM2
Mean 11.3
Standard deviation 0.74
Values 11 12
[97]
THLE DPM2
Mean 14.6
Standard deviation 2.8
Values 13 17
[98]
liver DPM2
Mean 7.64
Standard deviation 7.2
Values 13 0.97 15 2
[99]
ref_hepatocyte MPI
Mean 7.78
Standard deviation 6.3
Values 2.4 2.1 5.5 16 13
[100]
HepG2 MPI
Mean 24.9
Standard deviation 2.9
Values 27 23
[101]
HepG2.C3A MPI
Mean 16.3
Standard deviation 1.6
Values 17 15
[102]
HuH.7 MPI
Mean 29.1
Standard deviation 4.8
Values 33 24 31
[103]
SNU475 MPI
Mean 10.1
Standard deviation 2.3
Values 12 8.5
[104]
THLE MPI
Mean 13
Standard deviation 0.58
Values 13 13
[105]
liver MPI
Mean 11.4
Standard deviation 5.1
Values 15 8.4 16 5.8
[106]
ref_hepatocyte DHDDS
Mean 7.73
Standard deviation 4.3
Values 5.5 14 11 5.2 3.5
[107]
HepG2 DHDDS
Mean 15.7
Standard deviation 1.1
Values 15 16
[108]
HepG2.C3A DHDDS
Mean 23.3
Standard deviation 2.3
Values 22 25
[109]
HuH.7 DHDDS
Mean 13.2
Standard deviation 2.5
Values 15 10 14
[110]
SNU475 DHDDS
Mean 18.5
Standard deviation 0.043
Values 18 18
[111]
THLE DHDDS
Mean 14.8
Standard deviation 0.9
Values 14 15
[112]
liver DHDDS
Mean 7.61
Standard deviation 3.2
Values 7.9 6.3 12 4.3
[113]
ref_hepatocyte DOLK
Mean 5.16
Standard deviation 2.4
Values 2.7 4.3 8.8 6.1 3.9
[114]
HepG2 DOLK
Mean 11.1
Standard deviation 0.45
Values 11 11
[115]
HepG2.C3A DOLK
Mean 7.4
Standard deviation 0.73
Values 6.9 7.9
[116]
HuH.7 DOLK
Mean 8.25
Standard deviation 2.2
Values 9.9 5.8 9.1
[117]
SNU475 DOLK
Mean 7.21
Standard deviation 0.042
Values 7.2 7.2
[118]
THLE DOLK
Mean 8.39
Standard deviation 3
Values 6.3 11
[119]
liver DOLK
Mean 8.09
Standard deviation 4.6
Values 9.2 3.9 14 5.3
[120]
ref_hepatocyte SRD5A3
Mean 2.79
Standard deviation 1.2
Values 3.1 2.9 1.4 2.1 4.5
[121]
HepG2 SRD5A3
Mean 9.75
Standard deviation 3.5
Values 7.3 12
[122]
HepG2.C3A SRD5A3
Mean 6.61
Standard deviation 1.4
Values 5.6 7.6
[123]
HuH.7 SRD5A3
Mean 6.78
Standard deviation 0.38
Values 7.1 6.8 6.4
[124]
SNU475 SRD5A3
Mean 5.03
Standard deviation 0.79
Values 5.6 4.5
[125]
THLE SRD5A3
Mean 6.51
Standard deviation 1.2
Values 5.7 7.4
[126]
liver SRD5A3
Mean 5.36
Standard deviation 1.4
Values 5.9 3.5 6.9 5.1