REACTOME_DIGESTION_AND_ABSORPTION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 SLC2A2 Solute carrier family 2, facilitated glucose transporter member 2 [1] -0.90[2] -0.87[3] -1.81[4] -3.89[5] -6.78[6] 0.33[7]
2 PIR Pirin [8] -0.05[9] -0.95[10] -0.91[11] 1.82[12] 1.32[13] -4.43[14]
3 NPC1L1 Niemann-Pick C1-like protein 1 [15] 2.15[16] 2.37[17] 0.14[18] -4.84[19] -2.62[20] 0.43[21]
4 RSC1A1 Regulatory solute carrier protein family 1 member 1 [22] 1.43[23] 2.19[24] 0.35[25] 2.42[26] 3.36[27] -0.44[28]
5 TREH Trehalase [29] -0.38[30] -0.69[31] -5.97[32] -3.63[33] [34] -2.52[35]
6 GUCA2B Guanylate cyclase activator 2B [36] -4.04[37] -5.08[38] [39] [40] [41] -3.44[42]
7 AMY2B Alpha-amylase 2B [43] -1.04[44] 0.13[45] -0.03[46] 0.69[47] 3.54[48] 0.44[49]
8 PNLIPRP2 Pancreatic lipase-related protein 2 [50] -1.01[51] -0.44[52] -5.36[53] -5.73[54] [55] -8.43[56]
9 MGAM Maltase-glucoamylase, intestinal [57] -1.59[58] -0.41[59] 4.54[60] -2.56[61] 3.22[62] 0.26[63]
10 SLC2A5 Solute carrier family 2, facilitated glucose transporter member 5 [64] 3.89[65] 0.86[66] -3.99[67] 6.94[68] 5.78[69] -3.36[70]
11 CHIA Acidic mammalian chitinase [71] [72] [73] [74] [75] [76] [77]
12 CEL Bile salt-activated lipase [78] 5.67[79] 5.42[80] 0.49[81] 3.70[82] 5.24[83] -2.94[84]
13 GUCY2C Heat-stable enterotoxin receptor [85] 3.70[86] 2.39[87] 9.97[88] 3.23[89] 4.08[90] 0.05[91]
14 SLC5A1 Sodium/glucose cotransporter 1 [92] [93] [94] [95] 0.84[96] [97] 4.81[98]
15 AMY2A Pancreatic alpha-amylase [99] -0.57[100] [101] -4.15[102] [103] [104] [105]
16 CLPS Colipase [106] [107] [108] [109] [110] 0.28[111] -2.37[112]
17 LIPF Gastric triacylglycerol lipase [113] [114] [115] [116] [117] [118] [119]
18 AMY1C [120] [121] [122] [123] [124] [125] [126]
19 PNLIPRP1 Inactive pancreatic lipase-related protein 1 [127] [128] [129] [130] [131] [132] [133]
20 ALPI Intestinal-type alkaline phosphatase [134] [135] [136] [137] [138] [139] [140]
21 AMY1B [141] [142] [143] [144] [145] [146] [147]
22 SI Sucrase-isomaltase, intestinal [148] [149] [150] [151] [152] [153] [154]
23 PNLIPRP3 Pancreatic lipase-related protein 3 [155] [156] [157] [158] [159] [160] [161]
24 GUCA2A Guanylin [162] [163] [164] [165] [166] [167] [168]
25 AMY1A Alpha-amylase 1 [169] [170] [171] [172] [173] [174] [175]
26 PNLIP Pancreatic triacylglycerol lipase [176] [177] [178] [179] [180] [181] [182]
27 LCT Lactase-phlorizin hydrolase [183] [184] [185] [186] [187] [188] [189]
28 CHIT1 Chitotriosidase-1 [190] [191] [192] [193] [194] [195] [196]
[1]
ref_hepatocyte SLC2A2
Mean 50.4
Standard deviation 77
Values 3.6 23 0.5 39 1.9e+02
[2]
HepG2 SLC2A2
Mean 12.1
Standard deviation 6.3
Values 7.6 17
[3]
HepG2.C3A SLC2A2
Mean 18.4
Standard deviation 9.8
Values 11 25
[4]
HuH.7 SLC2A2
Mean 27.9
Standard deviation 5.4
Values 29 32 22
[5]
SNU475 SLC2A2
Mean 0.843
Standard deviation 0.21
Values 0.99 0.69
[6]
THLE SLC2A2
Mean 0.0458
Standard deviation 0.027
Values 0.065 0.027
[7]
liver SLC2A2
Mean 257
Standard deviation 32
Values 2.5e+02 2.6e+02 2.2e+02 2.9e+02
[8]
ref_hepatocyte PIR
Mean 13.5
Standard deviation 7.2
Values 10 12 5.7 25 15
[9]
HepG2 PIR
Mean 5.85
Standard deviation 1.9
Values 7.2 4.5
[10]
HepG2.C3A PIR
Mean 4.69
Standard deviation 1.4
Values 3.7 5.7
[11]
HuH.7 PIR
Mean 14
Standard deviation 1.9
Values 12 16 14
[12]
SNU475 PIR
Mean 11.8
Standard deviation 4.1
Values 15 9
[13]
THLE PIR
Mean 3.38
Standard deviation 0.35
Values 3.1 3.6
[14]
liver PIR
Mean 2.56
Standard deviation 2.2
Values 3.3 1.1 5.4 0.5
[15]
ref_hepatocyte NPC1L1
Mean 4.95
Standard deviation 3.9
Values 0.66 0.91 6.7 7.1 9.4
[16]
HepG2 NPC1L1
Mean 9.84
Standard deviation 3.5
Values 7.4 12
[17]
HepG2.C3A NPC1L1
Mean 17.1
Standard deviation 8.1
Values 23 11
[18]
HuH.7 NPC1L1
Mean 10.6
Standard deviation 1.7
Values 12 11 8.7
[19]
SNU475 NPC1L1
Mean 0.0428
Standard deviation 0.025
Values 0.06 0.025
[20]
THLE NPC1L1
Mean 0.0804
Standard deviation 0.054
Values 0.12 0.043
[21]
liver NPC1L1
Mean 27.2
Standard deviation 16
Values 32 12 47 17
[22]
ref_hepatocyte RSC1A1
Mean 1.96
Standard deviation 1.4
Values 1.1 0 3.6 2.6 2.6
[23]
HepG2 RSC1A1
Mean 2.37
Standard deviation 0.87
Values 1.8 3
[24]
HepG2.C3A RSC1A1
Mean 5.98
Standard deviation 2
Values 4.5 7.4
[25]
HuH.7 RSC1A1
Mean 4.87
Standard deviation 1.6
Values 6.2 5.3 3.1
[26]
SNU475 RSC1A1
Mean 2.59
Standard deviation 0.029
Values 2.6 2.6
[27]
THLE RSC1A1
Mean 2.01
Standard deviation 0.54
Values 1.6 2.4
[28]
liver RSC1A1
Mean 5.87
Standard deviation 4
Values 2.3 9 2.5 9.7
[29]
ref_hepatocyte TREH
Mean 0.836
Standard deviation 1.3
Values 0.064 0 0 1.1 3
[30]
HepG2 TREH
Mean 0.287
Standard deviation 0.049
Values 0.25 0.32
[31]
HepG2.C3A TREH
Mean 0.346
Standard deviation 0.034
Values 0.37 0.32
[32]
HuH.7 TREH
Mean 0.0259
Standard deviation 0.016
Values 0.0082 0.032 0.037
[33]
SNU475 TREH
Mean 0.0167
Standard deviation 0.0092
Values 0.023 0.01
[34]
THLE TREH
Mean 0
Standard deviation 0
Values 0 0
[35]
liver TREH
Mean 0.593
Standard deviation 0.24
Values 0.82 0.31 0.77 0.46
[36]
ref_hepatocyte GUCA2B
Mean 0.789
Standard deviation 0.74
Values 0 0.4 0.82 0.74 2
[37]
HepG2 GUCA2B
Mean 0.0215
Standard deviation 0.018
Values 0.034 0.0086
[38]
HepG2.C3A GUCA2B
Mean 0.0156
Standard deviation 0.0083
Values 0.0097 0.021
[39]
HuH.7 GUCA2B
Mean 0
Standard deviation 0
Values 0 0 0
[40]
SNU475 GUCA2B
Mean 0
Standard deviation 0
Values 0 0
[41]
THLE GUCA2B
Mean 0
Standard deviation 0
Values 0 0
[42]
liver GUCA2B
Mean 0.296
Standard deviation 0.36
Values 0.82 0.14 0.21 0.013
[43]
ref_hepatocyte AMY2B
Mean 0.651
Standard deviation 0.65
Values 0.76 0 0 1 1.5
[44]
HepG2 AMY2B
Mean 0.142
Standard deviation 0.054
Values 0.1 0.18
[45]
HepG2.C3A AMY2B
Mean 0.476
Standard deviation 0.097
Values 0.54 0.41
[46]
HuH.7 AMY2B
Mean 1.24
Standard deviation 0.095
Values 1.1 1.2 1.3
[47]
SNU475 AMY2B
Mean 0.261
Standard deviation 0.1
Values 0.33 0.19
[48]
THLE AMY2B
Mean 0.757
Standard deviation 0.47
Values 1.1 0.43
[49]
liver AMY2B
Mean 3.6
Standard deviation 1.7
Values 6.1 2.7 2.5 3.1
[50]
ref_hepatocyte PNLIPRP2
Mean 0.543
Standard deviation 1.2
Values 2.7 0 0 0 0
[51]
HepG2 PNLIPRP2
Mean 0.121
Standard deviation 0.017
Values 0.11 0.13
[52]
HepG2.C3A PNLIPRP2
Mean 0.267
Standard deviation 0.062
Values 0.22 0.31
[53]
HuH.7 PNLIPRP2
Mean 0.0258
Standard deviation 0.025
Values 0.049 0 0.028
[54]
SNU475 PNLIPRP2
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[55]
THLE PNLIPRP2
Mean 0
Standard deviation 0
Values 0 0
[56]
liver PNLIPRP2
Mean 0.00642
Standard deviation 0.013
Values 0 0 0.026 0
[57]
ref_hepatocyte MGAM
Mean 0.452
Standard deviation 0.68
Values 0.054 0.58 1.6 0.043 0
[58]
HepG2 MGAM
Mean 0.0673
Standard deviation 0.014
Values 0.057 0.077
[59]
HepG2.C3A MGAM
Mean 0.227
Standard deviation 0.088
Values 0.17 0.29
[60]
HuH.7 MGAM
Mean 20.5
Standard deviation 8.8
Values 17 31 14
[61]
SNU475 MGAM
Mean 0.019
Standard deviation 0.013
Values 0.028 0.01
[62]
THLE MGAM
Mean 0.421
Standard deviation 0.052
Values 0.38 0.46
[63]
liver MGAM
Mean 2.2
Standard deviation 2.8
Values 0.33 1.9 0.36 6.2
[64]
ref_hepatocyte SLC2A5
Mean 0.0767
Standard deviation 0.084
Values 0.19 0 0 0.06 0.13
[65]
HepG2 SLC2A5
Mean 0.51
Standard deviation 0.24
Values 0.68 0.34
[66]
HepG2.C3A SLC2A5
Mean 0.093
Standard deviation 0.035
Values 0.068 0.12
[67]
HuH.7 SLC2A5
Mean 0.00937
Standard deviation 0.016
Values 0 0 0.028
[68]
SNU475 SLC2A5
Mean 2.34
Standard deviation 0.73
Values 2.9 1.8
[69]
THLE SLC2A5
Mean 0.422
Standard deviation 0.19
Values 0.29 0.55
[70]
liver SLC2A5
Mean 0.0304
Standard deviation 0.043
Values 0.094 0.014 0 0.013
[71]
ref_hepatocyte CHIA
Mean 0.0658
Standard deviation 0.072
Values 0 0.17 0 0.1 0.057
[72]
HepG2 CHIA
Missing
[73]
HepG2.C3A CHIA
Missing
[74]
HuH.7 CHIA
Missing
[75]
SNU475 CHIA
Missing
[76]
THLE CHIA
Missing
[77]
liver CHIA
Missing
[78]
ref_hepatocyte CEL
Mean 0.0634
Standard deviation 0.059
Values 0.099 0 0 0.12 0.098
[79]
HepG2 CEL
Mean 1.45
Standard deviation 0.58
Values 1.9 1
[80]
HepG2.C3A CEL
Mean 1.82
Standard deviation 0.098
Values 1.7 1.9
[81]
HuH.7 CEL
Mean 0.173
Standard deviation 0.076
Values 0.16 0.1 0.25
[82]
SNU475 CEL
Mean 0.204
Standard deviation 0.02
Values 0.19 0.22
[83]
THLE CEL
Mean 0.239
Standard deviation 0.097
Values 0.31 0.17
[84]
liver CEL
Mean 0.0336
Standard deviation 0.05
Values 0 0.029 0 0.11
[85]
ref_hepatocyte GUCY2C
Mean 0.0318
Standard deviation 0.044
Values 0 0 0 0.078 0.081
[86]
HepG2 GUCY2C
Mean 0.185
Standard deviation 0.086
Values 0.25 0.12
[87]
HepG2.C3A GUCY2C
Mean 0.111
Standard deviation 0.036
Values 0.14 0.086
[88]
HuH.7 GUCY2C
Mean 62.1
Standard deviation 38
Values 38 1.1e+02 42
[89]
SNU475 GUCY2C
Mean 0.074
Standard deviation 0.033
Values 0.097 0.051
[90]
THLE GUCY2C
Mean 0.0538
Standard deviation 0.016
Values 0.065 0.043
[91]
liver GUCY2C
Mean 0.134
Standard deviation 0.15
Values 0.047 0.36 0.051 0.079
[92]
ref_hepatocyte SLC5A1
Mean 0.0286
Standard deviation 0.041
Values 0 0 0 0.086 0.057
[93]
HepG2 SLC5A1
Mean 0
Standard deviation 0
Values 0 0
[94]
HepG2.C3A SLC5A1
Mean 0
Standard deviation 0
Values 0 0
[95]
HuH.7 SLC5A1
Mean 0
Standard deviation 0
Values 0 0 0
[96]
SNU475 SLC5A1
Mean 0.0127
Standard deviation 0.018
Values 0 0.025
[97]
THLE SLC5A1
Mean 0
Standard deviation 0
Values 0 0
[98]
liver SLC5A1
Mean 3.28
Standard deviation 2
Values 5.7 1.4 1.8 4.2
[99]
ref_hepatocyte AMY2A
Mean 0.0285
Standard deviation 0.064
Values 0 0.14 0 0 0
[100]
HepG2 AMY2A
Mean 0.00858
Standard deviation 0.012
Values 0 0.017
[101]
HepG2.C3A AMY2A
Mean 0
Standard deviation 0
Values 0 0
[102]
HuH.7 AMY2A
Mean 0.00312
Standard deviation 0.0054
Values 0 0 0.0094
[103]
SNU475 AMY2A
Mean 0
Standard deviation 0
Values 0 0
[104]
THLE AMY2A
Mean 0
Standard deviation 0
Values 0 0
[105]
liver AMY2A
Mean 0
Standard deviation 0
Values 0 0 0 0
[106]
ref_hepatocyte CLPS
Mean 0.0244
Standard deviation 0.055
Values 0 0 0 0 0.12
[107]
HepG2 CLPS
Mean 0
Standard deviation 0
Values 0 0
[108]
HepG2.C3A CLPS
Mean 0
Standard deviation 0
Values 0 0
[109]
HuH.7 CLPS
Mean 0
Standard deviation 0
Values 0 0 0
[110]
SNU475 CLPS
Mean 0
Standard deviation 0
Values 0 0
[111]
THLE CLPS
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[112]
liver CLPS
Mean 0.0193
Standard deviation 0.039
Values 0 0 0.077 0
[113]
ref_hepatocyte LIPF
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[114]
HepG2 LIPF
Mean 0
Standard deviation 0
Values 0 0
[115]
HepG2.C3A LIPF
Mean 0
Standard deviation 0
Values 0 0
[116]
HuH.7 LIPF
Mean 0
Standard deviation 0
Values 0 0 0
[117]
SNU475 LIPF
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[118]
THLE LIPF
Mean 0
Standard deviation 0
Values 0 0
[119]
liver LIPF
Mean 0
Standard deviation 0
Values 0 0 0 0
[120]
ref_hepatocyte AMY1C
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[121]
HepG2 AMY1C
Missing
[122]
HepG2.C3A AMY1C
Missing
[123]
HuH.7 AMY1C
Missing
[124]
SNU475 AMY1C
Missing
[125]
THLE AMY1C
Missing
[126]
liver AMY1C
Missing
[127]
ref_hepatocyte PNLIPRP1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[128]
HepG2 PNLIPRP1
Mean 0
Standard deviation 0
Values 0 0
[129]
HepG2.C3A PNLIPRP1
Mean 0
Standard deviation 0
Values 0 0
[130]
HuH.7 PNLIPRP1
Mean 0
Standard deviation 0
Values 0 0 0
[131]
SNU475 PNLIPRP1
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[132]
THLE PNLIPRP1
Mean 0
Standard deviation 0
Values 0 0
[133]
liver PNLIPRP1
Mean 0
Standard deviation 0
Values 0 0 0 0
[134]
ref_hepatocyte ALPI
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[135]
HepG2 ALPI
Mean 0.318
Standard deviation 0.3
Values 0.53 0.1
[136]
HepG2.C3A ALPI
Mean 0.0107
Standard deviation 0.015
Values 0 0.021
[137]
HuH.7 ALPI
Mean 0.45
Standard deviation 0.1
Values 0.42 0.56 0.37
[138]
SNU475 ALPI
Mean 0
Standard deviation 0
Values 0 0
[139]
THLE ALPI
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[140]
liver ALPI
Mean 0
Standard deviation 0
Values 0 0 0 0
[141]
ref_hepatocyte AMY1B
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[142]
HepG2 AMY1B
Missing
[143]
HepG2.C3A AMY1B
Missing
[144]
HuH.7 AMY1B
Missing
[145]
SNU475 AMY1B
Missing
[146]
THLE AMY1B
Missing
[147]
liver AMY1B
Missing
[148]
ref_hepatocyte SI
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[149]
HepG2 SI
Mean 0.00573
Standard deviation 0.0081
Values 0.011 0
[150]
HepG2.C3A SI
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[151]
HuH.7 SI
Mean 2.83
Standard deviation 2
Values 1.9 5.1 1.5
[152]
SNU475 SI
Mean 0
Standard deviation 0
Values 0 0
[153]
THLE SI
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[154]
liver SI
Mean 0
Standard deviation 0
Values 0 0 0 0
[155]
ref_hepatocyte PNLIPRP3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[156]
HepG2 PNLIPRP3
Mean 0
Standard deviation 0
Values 0 0
[157]
HepG2.C3A PNLIPRP3
Mean 0
Standard deviation 0
Values 0 0
[158]
HuH.7 PNLIPRP3
Mean 0
Standard deviation 0
Values 0 0 0
[159]
SNU475 PNLIPRP3
Mean 0.0076
Standard deviation 0.011
Values 0 0.015
[160]
THLE PNLIPRP3
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[161]
liver PNLIPRP3
Mean 0
Standard deviation 0
Values 0 0 0 0
[162]
ref_hepatocyte GUCA2A
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[163]
HepG2 GUCA2A
Mean 0.0801
Standard deviation 0.081
Values 0.023 0.14
[164]
HepG2.C3A GUCA2A
Mean 0.136
Standard deviation 0.11
Values 0.058 0.21
[165]
HuH.7 GUCA2A
Mean 0
Standard deviation 0
Values 0 0 0
[166]
SNU475 GUCA2A
Mean 0
Standard deviation 0
Values 0 0
[167]
THLE GUCA2A
Mean 0
Standard deviation 0
Values 0 0
[168]
liver GUCA2A
Mean 0.0118
Standard deviation 0.024
Values 0.047 0 0 0
[169]
ref_hepatocyte AMY1A
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[170]
HepG2 AMY1A
Missing
[171]
HepG2.C3A AMY1A
Missing
[172]
HuH.7 AMY1A
Missing
[173]
SNU475 AMY1A
Missing
[174]
THLE AMY1A
Missing
[175]
liver AMY1A
Missing
[176]
ref_hepatocyte PNLIP
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[177]
HepG2 PNLIP
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[178]
HepG2.C3A PNLIP
Mean 0
Standard deviation 0
Values 0 0
[179]
HuH.7 PNLIP
Mean 0
Standard deviation 0
Values 0 0 0
[180]
SNU475 PNLIP
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[181]
THLE PNLIP
Mean 0
Standard deviation 0
Values 0 0
[182]
liver PNLIP
Mean 0.0128
Standard deviation 0.026
Values 0 0 0.051 0
[183]
ref_hepatocyte LCT
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[184]
HepG2 LCT
Mean 0.0122
Standard deviation 0.001
Values 0.011 0.013
[185]
HepG2.C3A LCT
Mean 0.00972
Standard deviation 0.014
Values 0.019 0
[186]
HuH.7 LCT
Mean 0.0351
Standard deviation 0.033
Values 0.041 0.064 0
[187]
SNU475 LCT
Mean 0.0226
Standard deviation 0.025
Values 0.0046 0.041
[188]
THLE LCT
Mean 0.0109
Standard deviation 0.0071
Values 0.0059 0.016
[189]
liver LCT
Mean 0.07
Standard deviation 0.082
Values 0.024 0.071 0 0.19
[190]
ref_hepatocyte CHIT1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[191]
HepG2 CHIT1
Mean 0
Standard deviation 0
Values 0 0
[192]
HepG2.C3A CHIT1
Mean 0
Standard deviation 0
Values 0 0
[193]
HuH.7 CHIT1
Mean 0
Standard deviation 0
Values 0 0 0
[194]
SNU475 CHIT1
Mean 0.134
Standard deviation 0.012
Values 0.13 0.14
[195]
THLE CHIT1
Mean 0
Standard deviation 0
Values 0 0
[196]
liver CHIT1
Mean 0.0406
Standard deviation 0.03
Values 0 0.071 0.051 0.04