REACTOME_DIGESTION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 PIR Pirin [1] -0.22[2] -0.46[3] -2.53[4] 0.24[5] -0.20[6] -1.57[7]
2 TREH Trehalase [8] -0.55[9] -0.21[10] -7.59[11] -5.21[12] [13] 0.33[14]
3 GUCA2B Guanylate cyclase activator 2B [15] -4.21[16] -4.59[17] [18] [19] [20] -0.59[21]
4 AMY2B Alpha-amylase 2B [22] -1.21[23] 0.62[24] -1.65[25] -0.89[26] 2.02[27] 3.29[28]
5 PNLIPRP2 Pancreatic lipase-related protein 2 [29] -1.17[30] 0.04[31] -6.97[32] -7.31[33] [34] -5.57[35]
6 MGAM Maltase-glucoamylase, intestinal [36] -1.76[37] 0.08[38] 2.93[39] -4.14[40] 1.70[41] 3.11[42]
7 CHIA Acidic mammalian chitinase [43] [44] [45] [46] [47] [48] [49]
8 CEL Bile salt-activated lipase [50] 5.50[51] 5.91[52] -1.13[53] 2.12[54] 3.72[55] -0.09[56]
9 GUCY2C Heat-stable enterotoxin receptor [57] 3.54[58] 2.87[59] 8.36[60] 1.65[61] 2.56[62] 2.90[63]
10 AMY2A Pancreatic alpha-amylase [64] -0.74[65] [66] -5.76[67] [68] [69] [70]
11 CLPS Colipase [71] [72] [73] [74] [75] -1.24[76] 0.49[77]
12 LCT Lactase-phlorizin hydrolase [78] [79] [80] [81] [82] [83] [84]
13 PNLIP Pancreatic triacylglycerol lipase [85] [86] [87] [88] [89] [90] [91]
14 CHIT1 Chitotriosidase-1 [92] [93] [94] [95] [96] [97] [98]
15 PNLIPRP3 Pancreatic lipase-related protein 3 [99] [100] [101] [102] [103] [104] [105]
16 AMY1A Alpha-amylase 1 [106] [107] [108] [109] [110] [111] [112]
17 GUCA2A Guanylin [113] [114] [115] [116] [117] [118] [119]
18 SI Sucrase-isomaltase, intestinal [120] [121] [122] [123] [124] [125] [126]
19 LIPF Gastric triacylglycerol lipase [127] [128] [129] [130] [131] [132] [133]
20 AMY1C [134] [135] [136] [137] [138] [139] [140]
21 AMY1B [141] [142] [143] [144] [145] [146] [147]
22 ALPI Intestinal-type alkaline phosphatase [148] [149] [150] [151] [152] [153] [154]
23 PNLIPRP1 Inactive pancreatic lipase-related protein 1 [155] [156] [157] [158] [159] [160] [161]
[1]
ref_hepatocyte PIR
Mean 13.5
Standard deviation 7.2
Values 10 12 5.7 25 15
[2]
HepG2 PIR
Mean 5.85
Standard deviation 1.9
Values 7.2 4.5
[3]
HepG2.C3A PIR
Mean 4.69
Standard deviation 1.4
Values 3.7 5.7
[4]
HuH.7 PIR
Mean 14
Standard deviation 1.9
Values 12 16 14
[5]
SNU475 PIR
Mean 11.8
Standard deviation 4.1
Values 15 9
[6]
THLE PIR
Mean 3.38
Standard deviation 0.35
Values 3.1 3.6
[7]
liver PIR
Mean 2.56
Standard deviation 2.2
Values 3.3 1.1 5.4 0.5
[8]
ref_hepatocyte TREH
Mean 0.836
Standard deviation 1.3
Values 0.064 0 0 1.1 3
[9]
HepG2 TREH
Mean 0.287
Standard deviation 0.049
Values 0.25 0.32
[10]
HepG2.C3A TREH
Mean 0.346
Standard deviation 0.034
Values 0.37 0.32
[11]
HuH.7 TREH
Mean 0.0259
Standard deviation 0.016
Values 0.0082 0.032 0.037
[12]
SNU475 TREH
Mean 0.0167
Standard deviation 0.0092
Values 0.023 0.01
[13]
THLE TREH
Mean 0
Standard deviation 0
Values 0 0
[14]
liver TREH
Mean 0.593
Standard deviation 0.24
Values 0.82 0.31 0.77 0.46
[15]
ref_hepatocyte GUCA2B
Mean 0.789
Standard deviation 0.74
Values 0 0.4 0.82 0.74 2
[16]
HepG2 GUCA2B
Mean 0.0215
Standard deviation 0.018
Values 0.034 0.0086
[17]
HepG2.C3A GUCA2B
Mean 0.0156
Standard deviation 0.0083
Values 0.0097 0.021
[18]
HuH.7 GUCA2B
Mean 0
Standard deviation 0
Values 0 0 0
[19]
SNU475 GUCA2B
Mean 0
Standard deviation 0
Values 0 0
[20]
THLE GUCA2B
Mean 0
Standard deviation 0
Values 0 0
[21]
liver GUCA2B
Mean 0.296
Standard deviation 0.36
Values 0.82 0.14 0.21 0.013
[22]
ref_hepatocyte AMY2B
Mean 0.651
Standard deviation 0.65
Values 0.76 0 0 1 1.5
[23]
HepG2 AMY2B
Mean 0.142
Standard deviation 0.054
Values 0.1 0.18
[24]
HepG2.C3A AMY2B
Mean 0.476
Standard deviation 0.097
Values 0.54 0.41
[25]
HuH.7 AMY2B
Mean 1.24
Standard deviation 0.095
Values 1.1 1.2 1.3
[26]
SNU475 AMY2B
Mean 0.261
Standard deviation 0.1
Values 0.33 0.19
[27]
THLE AMY2B
Mean 0.757
Standard deviation 0.47
Values 1.1 0.43
[28]
liver AMY2B
Mean 3.6
Standard deviation 1.7
Values 6.1 2.7 2.5 3.1
[29]
ref_hepatocyte PNLIPRP2
Mean 0.543
Standard deviation 1.2
Values 2.7 0 0 0 0
[30]
HepG2 PNLIPRP2
Mean 0.121
Standard deviation 0.017
Values 0.11 0.13
[31]
HepG2.C3A PNLIPRP2
Mean 0.267
Standard deviation 0.062
Values 0.22 0.31
[32]
HuH.7 PNLIPRP2
Mean 0.0258
Standard deviation 0.025
Values 0.049 0 0.028
[33]
SNU475 PNLIPRP2
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[34]
THLE PNLIPRP2
Mean 0
Standard deviation 0
Values 0 0
[35]
liver PNLIPRP2
Mean 0.00642
Standard deviation 0.013
Values 0 0 0.026 0
[36]
ref_hepatocyte MGAM
Mean 0.452
Standard deviation 0.68
Values 0.054 0.58 1.6 0.043 0
[37]
HepG2 MGAM
Mean 0.0673
Standard deviation 0.014
Values 0.057 0.077
[38]
HepG2.C3A MGAM
Mean 0.227
Standard deviation 0.088
Values 0.17 0.29
[39]
HuH.7 MGAM
Mean 20.5
Standard deviation 8.8
Values 17 31 14
[40]
SNU475 MGAM
Mean 0.019
Standard deviation 0.013
Values 0.028 0.01
[41]
THLE MGAM
Mean 0.421
Standard deviation 0.052
Values 0.38 0.46
[42]
liver MGAM
Mean 2.2
Standard deviation 2.8
Values 0.33 1.9 0.36 6.2
[43]
ref_hepatocyte CHIA
Mean 0.0658
Standard deviation 0.072
Values 0 0.17 0 0.1 0.057
[44]
HepG2 CHIA
Missing
[45]
HepG2.C3A CHIA
Missing
[46]
HuH.7 CHIA
Missing
[47]
SNU475 CHIA
Missing
[48]
THLE CHIA
Missing
[49]
liver CHIA
Missing
[50]
ref_hepatocyte CEL
Mean 0.0634
Standard deviation 0.059
Values 0.099 0 0 0.12 0.098
[51]
HepG2 CEL
Mean 1.45
Standard deviation 0.58
Values 1.9 1
[52]
HepG2.C3A CEL
Mean 1.82
Standard deviation 0.098
Values 1.7 1.9
[53]
HuH.7 CEL
Mean 0.173
Standard deviation 0.076
Values 0.16 0.1 0.25
[54]
SNU475 CEL
Mean 0.204
Standard deviation 0.02
Values 0.19 0.22
[55]
THLE CEL
Mean 0.239
Standard deviation 0.097
Values 0.31 0.17
[56]
liver CEL
Mean 0.0336
Standard deviation 0.05
Values 0 0.029 0 0.11
[57]
ref_hepatocyte GUCY2C
Mean 0.0318
Standard deviation 0.044
Values 0 0 0 0.078 0.081
[58]
HepG2 GUCY2C
Mean 0.185
Standard deviation 0.086
Values 0.25 0.12
[59]
HepG2.C3A GUCY2C
Mean 0.111
Standard deviation 0.036
Values 0.14 0.086
[60]
HuH.7 GUCY2C
Mean 62.1
Standard deviation 38
Values 38 1.1e+02 42
[61]
SNU475 GUCY2C
Mean 0.074
Standard deviation 0.033
Values 0.097 0.051
[62]
THLE GUCY2C
Mean 0.0538
Standard deviation 0.016
Values 0.065 0.043
[63]
liver GUCY2C
Mean 0.134
Standard deviation 0.15
Values 0.047 0.36 0.051 0.079
[64]
ref_hepatocyte AMY2A
Mean 0.0285
Standard deviation 0.064
Values 0 0.14 0 0 0
[65]
HepG2 AMY2A
Mean 0.00858
Standard deviation 0.012
Values 0 0.017
[66]
HepG2.C3A AMY2A
Mean 0
Standard deviation 0
Values 0 0
[67]
HuH.7 AMY2A
Mean 0.00312
Standard deviation 0.0054
Values 0 0 0.0094
[68]
SNU475 AMY2A
Mean 0
Standard deviation 0
Values 0 0
[69]
THLE AMY2A
Mean 0
Standard deviation 0
Values 0 0
[70]
liver AMY2A
Mean 0
Standard deviation 0
Values 0 0 0 0
[71]
ref_hepatocyte CLPS
Mean 0.0244
Standard deviation 0.055
Values 0 0 0 0 0.12
[72]
HepG2 CLPS
Mean 0
Standard deviation 0
Values 0 0
[73]
HepG2.C3A CLPS
Mean 0
Standard deviation 0
Values 0 0
[74]
HuH.7 CLPS
Mean 0
Standard deviation 0
Values 0 0 0
[75]
SNU475 CLPS
Mean 0
Standard deviation 0
Values 0 0
[76]
THLE CLPS
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[77]
liver CLPS
Mean 0.0193
Standard deviation 0.039
Values 0 0 0.077 0
[78]
ref_hepatocyte LCT
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[79]
HepG2 LCT
Mean 0.0122
Standard deviation 0.001
Values 0.011 0.013
[80]
HepG2.C3A LCT
Mean 0.00972
Standard deviation 0.014
Values 0.019 0
[81]
HuH.7 LCT
Mean 0.0351
Standard deviation 0.033
Values 0.041 0.064 0
[82]
SNU475 LCT
Mean 0.0226
Standard deviation 0.025
Values 0.0046 0.041
[83]
THLE LCT
Mean 0.0109
Standard deviation 0.0071
Values 0.0059 0.016
[84]
liver LCT
Mean 0.07
Standard deviation 0.082
Values 0.024 0.071 0 0.19
[85]
ref_hepatocyte PNLIP
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[86]
HepG2 PNLIP
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[87]
HepG2.C3A PNLIP
Mean 0
Standard deviation 0
Values 0 0
[88]
HuH.7 PNLIP
Mean 0
Standard deviation 0
Values 0 0 0
[89]
SNU475 PNLIP
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[90]
THLE PNLIP
Mean 0
Standard deviation 0
Values 0 0
[91]
liver PNLIP
Mean 0.0128
Standard deviation 0.026
Values 0 0 0.051 0
[92]
ref_hepatocyte CHIT1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[93]
HepG2 CHIT1
Mean 0
Standard deviation 0
Values 0 0
[94]
HepG2.C3A CHIT1
Mean 0
Standard deviation 0
Values 0 0
[95]
HuH.7 CHIT1
Mean 0
Standard deviation 0
Values 0 0 0
[96]
SNU475 CHIT1
Mean 0.134
Standard deviation 0.012
Values 0.13 0.14
[97]
THLE CHIT1
Mean 0
Standard deviation 0
Values 0 0
[98]
liver CHIT1
Mean 0.0406
Standard deviation 0.03
Values 0 0.071 0.051 0.04
[99]
ref_hepatocyte PNLIPRP3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[100]
HepG2 PNLIPRP3
Mean 0
Standard deviation 0
Values 0 0
[101]
HepG2.C3A PNLIPRP3
Mean 0
Standard deviation 0
Values 0 0
[102]
HuH.7 PNLIPRP3
Mean 0
Standard deviation 0
Values 0 0 0
[103]
SNU475 PNLIPRP3
Mean 0.0076
Standard deviation 0.011
Values 0 0.015
[104]
THLE PNLIPRP3
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[105]
liver PNLIPRP3
Mean 0
Standard deviation 0
Values 0 0 0 0
[106]
ref_hepatocyte AMY1A
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[107]
HepG2 AMY1A
Missing
[108]
HepG2.C3A AMY1A
Missing
[109]
HuH.7 AMY1A
Missing
[110]
SNU475 AMY1A
Missing
[111]
THLE AMY1A
Missing
[112]
liver AMY1A
Missing
[113]
ref_hepatocyte GUCA2A
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[114]
HepG2 GUCA2A
Mean 0.0801
Standard deviation 0.081
Values 0.023 0.14
[115]
HepG2.C3A GUCA2A
Mean 0.136
Standard deviation 0.11
Values 0.058 0.21
[116]
HuH.7 GUCA2A
Mean 0
Standard deviation 0
Values 0 0 0
[117]
SNU475 GUCA2A
Mean 0
Standard deviation 0
Values 0 0
[118]
THLE GUCA2A
Mean 0
Standard deviation 0
Values 0 0
[119]
liver GUCA2A
Mean 0.0118
Standard deviation 0.024
Values 0.047 0 0 0
[120]
ref_hepatocyte SI
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[121]
HepG2 SI
Mean 0.00573
Standard deviation 0.0081
Values 0.011 0
[122]
HepG2.C3A SI
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[123]
HuH.7 SI
Mean 2.83
Standard deviation 2
Values 1.9 5.1 1.5
[124]
SNU475 SI
Mean 0
Standard deviation 0
Values 0 0
[125]
THLE SI
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[126]
liver SI
Mean 0
Standard deviation 0
Values 0 0 0 0
[127]
ref_hepatocyte LIPF
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[128]
HepG2 LIPF
Mean 0
Standard deviation 0
Values 0 0
[129]
HepG2.C3A LIPF
Mean 0
Standard deviation 0
Values 0 0
[130]
HuH.7 LIPF
Mean 0
Standard deviation 0
Values 0 0 0
[131]
SNU475 LIPF
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[132]
THLE LIPF
Mean 0
Standard deviation 0
Values 0 0
[133]
liver LIPF
Mean 0
Standard deviation 0
Values 0 0 0 0
[134]
ref_hepatocyte AMY1C
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[135]
HepG2 AMY1C
Missing
[136]
HepG2.C3A AMY1C
Missing
[137]
HuH.7 AMY1C
Missing
[138]
SNU475 AMY1C
Missing
[139]
THLE AMY1C
Missing
[140]
liver AMY1C
Missing
[141]
ref_hepatocyte AMY1B
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[142]
HepG2 AMY1B
Missing
[143]
HepG2.C3A AMY1B
Missing
[144]
HuH.7 AMY1B
Missing
[145]
SNU475 AMY1B
Missing
[146]
THLE AMY1B
Missing
[147]
liver AMY1B
Missing
[148]
ref_hepatocyte ALPI
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[149]
HepG2 ALPI
Mean 0.318
Standard deviation 0.3
Values 0.53 0.1
[150]
HepG2.C3A ALPI
Mean 0.0107
Standard deviation 0.015
Values 0 0.021
[151]
HuH.7 ALPI
Mean 0.45
Standard deviation 0.1
Values 0.42 0.56 0.37
[152]
SNU475 ALPI
Mean 0
Standard deviation 0
Values 0 0
[153]
THLE ALPI
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[154]
liver ALPI
Mean 0
Standard deviation 0
Values 0 0 0 0
[155]
ref_hepatocyte PNLIPRP1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[156]
HepG2 PNLIPRP1
Mean 0
Standard deviation 0
Values 0 0
[157]
HepG2.C3A PNLIPRP1
Mean 0
Standard deviation 0
Values 0 0
[158]
HuH.7 PNLIPRP1
Mean 0
Standard deviation 0
Values 0 0 0
[159]
SNU475 PNLIPRP1
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[160]
THLE PNLIPRP1
Mean 0
Standard deviation 0
Values 0 0
[161]
liver PNLIPRP1
Mean 0
Standard deviation 0
Values 0 0 0 0